900 16 amale spermato - Rutgers...
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Page 1 Meetings 01-02: Introduction to Animal Reproduction (2) Meetings 03-04: Reproductive Structures and their Functions (2) Meetings 05-07: The HPG axis and its Liposoluble and Watersoluble Hormones (3) Meetings 08-09: The Neuroendocrine Control of Male and Female Puberty Onset (2) Meetings 10-11: REVIEW AND TEST #1 Meetings 12-17: Female and Male Reproduction and Techniques for their Control (6) Meetings 18-19: REVIEW AND TEST #2 Meetings 20-21: Reproductive Behavior and the Spermatozoa in the Female Tract (2) Meetings 22-23: Embryogenesis, Placentation, Parturition and Lactation (3) Meetings 24-25: Puerperium, Lactation and Reproductive Ageing (2) Meeting 26 Reproductive Pathology and Case Studies (1) Meetings 27-28: REVIEW AND TEST #3 AND TEST #4 Animal Reproduction 16 • JP Advis DVM, Ph.D. Bartlett Hall, Animal Sciences, Cook, (732) 932 - 9240, [email protected] • Course website: rci.rutgers.edu/~advis • Material to be covered: • About lecture slides: • There are not intended to be the sole source for studying the course material !!!!!!!!!!!!!!!! • Slides are good to review the course material after you have study your course textbook • Slides are a good indicator of the relative importance of lecture topics (see slide # per topic) • Group slides by titles when using them to review course material. Match lectures and text. Male Reproduction # lectures for cumulative test # 02 book 12 Reproductive cyclicity: terminology and basic concepts 1 - 9 13 Reproductive cyclicity: the follicular phase 1 - 9 14 Reproductive cyclicity: the luteal phase 1 - 9 15 Reproductive cyclicity: techniques for controlling female reproductive processes 1 - 9 16 Endocrinology of the male and the spermatogenesis process 1 - 10 17 Endocrinology of the male and techniques to control male reproductive processes 1 - 10 18 REVIEW – material from lecture # 12 through lecture # 17 1 - 10 19 EXAM # 02 - material from lecture # 01 through lecture # 18 1 - 10
Transcript of 900 16 amale spermato - Rutgers...
Page 1
Meetings 01-02: Introduction to Animal Reproduction (2) Meetings 03-04: Reproductive Structures and their Functions (2)
Meetings 05-07: The HPG axis and its Liposoluble and Watersoluble Hormones (3) Meetings 08-09: The Neuroendocrine Control of Male and Female Puberty Onset (2)
Meetings 10-11: REVIEW AND TEST #1 Meetings 12-17: Female and Male Reproduction and Techniques for their Control (6) Meetings 18-19: REVIEW AND TEST #2
Meetings 20-21: Reproductive Behavior and the Spermatozoa in the Female Tract (2) Meetings 22-23: Embryogenesis, Placentation, Parturition and Lactation (3)
Meetings 24-25: Puerperium, Lactation and Reproductive Ageing (2) Meeting 26 Reproductive Pathology and Case Studies (1) Meetings 27-28: REVIEW AND TEST #3 AND TEST #4
Animal Reproduction 16
• JP Advis DVM, Ph.D.
Bartlett Hall, Animal Sciences, Cook,
(732) 932 - 9240, [email protected]
• Course website: rci.rutgers.edu/~advis
• Material to
be covered:
• About
lecture
slides: • There are not intended to be the sole source for studying the course material !!!!!!!!!!!!!!!!
• Slides are good to review the course material after you have study your course textbook
• Slides are a good indicator of the relative importance of lecture topics (see slide # per topic)
• Group slides by titles when using them to review course material. Match lectures and text.
Male Reproduction
# lectures for cumulative test # 02 book
12 Reproductive cyclicity: terminology and basic concepts 1 - 9
13 Reproductive cyclicity: the follicular phase 1 - 9
14 Reproductive cyclicity: the luteal phase 1 - 9
15 Reproductive cyclicity: techniques for controlling female reproductive processes
1 - 9
16 Endocrinology of the male and the spermatogenesis process 1 - 10
17 Endocrinology of the male and techniques to control male reproductive processes
1 - 10
18 REVIEW – material from lecture # 12 through lecture # 17 1 - 10
19 EXAM # 02 - material from lecture # 01 through lecture # 18 1 - 10
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LECTURE #16
The male HPG axis continuous (non-cyclic) function, pulsatile LH, Leydig and Sertoli cells, hypothalamus and anterior pituitary, sexual accesory organs
Spermatogenesis
seminiferous tubules and their proliferation, meiotic and differentiation phases
The spermatozoon
anatomy, structure / function,
energy sources, abnormalities
Neuroendocrine control
HPG axis & photoperiodic cues
Male Reproduction
The anatomy of the male’s reproductive tract.
LECTURE #16
The male HPG axis continuous (non-cyclic) function, pulsatile LH, Leydig and Sertoli cells, hypothalamus and anterior pituitary, sexual accesory organs
Spermatogenesis
seminiferous tubules and their proliferation, meiotic and differentiation phases
The spermatozoon
anatomy, structure / function,
energy sources, abnormalities
Neuroendocrine control
HPG axis & photoperiodic cues
Male Reproduction
The physiology of the male’s reproductive tract.
Page 3
LECTURE #16
The male HPG axis continuous (non-cyclic) function, pulsatile LH, Leydig and Sertoli cells, hypothalamus and anterior pituitary, sexual accesory organs
Spermatogenesis
seminiferous tubules and their proliferation, meiotic and differentiation phases
The spermatozoon
anatomy, structure / function,
energy sources, abnormalities
Neuroendocrine control
HPG axis & photoperiodic cues
Male Reproduction
The endocrinology of the male’s reproductive tract.
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LECTURE #16
The male HPG axis continuous (non-cyclic) function, pulsatile LH, Leydig and Sertoli cells, hypothalamus and anterior pituitary, sexual accesory organs
Spermatogenesis
seminiferous tubules and their proliferation, meiotic and differentiation phases
The spermatozoon
anatomy, structure / function,
energy sources, abnormalities
Neuroendocrine control
HPG axis & photoperiodic cues
Male Reproduction
The spermatogenesis in the male’s reproductive tract.
Male Reproduction
The reflex path for erection of the male’s reproductive tract.
LECTURE #16
The male HPG axis continuous (non-cyclic) function, pulsatile LH, Leydig and Sertoli cells, hypothalamus and anterior pituitary, sexual accesory organs
Spermatogenesis
seminiferous tubules and their proliferation, meiotic and differentiation phases
The spermatozoon
anatomy, structure / function,
energy sources, abnormalities
Neuroendocrine control
HPG axis & photoperiodic cues
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LECTURE #16
The male HPG axis continuous (non-cyclic) function, pulsatile LH, Leydig and Sertoli cells, hypothalamus and anterior pituitary, sexual accesory organs
Spermatogenesis
seminiferous tubules and their proliferation, meiotic and differentiation phases
The spermatozoon
anatomy, structure / function,
energy sources, abnormalities
Neuroendocrine control
HPG axis & photoperiodic cues
Male Reproduction
The hypothalamic–pituitary–gonadal axis in males & females.
LECTURE #16
The male HPG axis continuous (non-cyclic) function, pulsatile LH, Leydig and Sertoli cells, hypothalamus and anterior pituitary, sexual accesory organs
Spermatogenesis
seminiferous tubules and their proliferation, meiotic and differentiation phases
The spermatozoon
anatomy, structure / function,
energy sources, abnormalities
Neuroendocrine control
HPG axis & photoperiodic cues
Male Reproduction
Action of testosterone.
Testosterone (T) enters target cell and binds to its nuclear
androgen receptor (AR) either directly or after it is converted
to 5 -dihydrotestosterone (DHT). The thickness of the
arrows reflects the quantitative importance of each reaction.
The hormone–receptor complex binds DNA along with a variety
of cell-specific nuclear regulatory proteins to induce
formation of the RNA that encodes the proteins that
express effects of the hormone.
Not shown: T may also bind to membrane receptors & initiate
rapid ionic changes that may reinforce its genomic effects.
T may also produce rapid changes in cAMP production
through binding of the sex hormone binding globulin
(SHBG) to surface receptors.
The main steroids and their mechanism of action in males
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LECTURE #16
The male HPG axis continuous (non-cyclic) function, pulsatile LH, Leydig and Sertoli cells, hypothalamus and anterior pituitary, sexual accesory organs
Spermatogenesis
seminiferous tubules and their proliferation, meiotic and differentiation phases
The spermatozoon
anatomy, structure / function,
energy sources, abnormalities
Neuroendocrine control
HPG axis & photoperiodic cues
Male Reproduction
The main link between GnRH and gonadotropin secretion.
Page 7
LECTURE #16
The male HPG axis continuous (non-cyclic) function, pulsatile LH, Leydig and Sertoli cells, hypothalamus and anterior pituitary, sexual accesory organs
Spermatogenesis
seminiferous tubules and their proliferation, meiotic and differentiation phases
The spermatozoon
anatomy, structure / function,
energy sources, abnormalities
Neuroendocrine control
HPG axis & photoperiodic cues
Male Reproduction
The main link between LH and testosterone secretion.
LECTURE #16
The male HPG axis continuous (non-cyclic) function, pulsatile LH, Leydig and Sertoli cells, hypothalamus and anterior pituitary, sexual accesory organs
Spermatogenesis
seminiferous tubules and their proliferation, meiotic and differentiation phases
The spermatozoon
anatomy, structure / function,
energy sources, abnormalities
Neuroendocrine control
HPG axis & photoperiodic cues
Male Reproduction
Interrelationship among hormones produced by Sertoli and
Leydig cells, hypothalamus and anterior pituitary in males.
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LECTURE #16
The male HPG axis continuous (non-cyclic) function, pulsatile LH, Leydig and Sertoli cells, hypothalamus and anterior pituitary, sexual accesory organs
Spermatogenesis
seminiferous tubules and their proliferation, meiotic and differentiation phases
The spermatozoon
anatomy, structure / function,
energy sources, abnormalities
Neuroendocrine control
HPG axis & photoperiodic cues
Male Reproduction
Ilustration of the scrotum, the connective tissue supporting
structures and the tubular pathway in mammalian testis.
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LECTURE #16
The male HPG axis continuous (non-cyclic) function, pulsatile LH, Leydig and Sertoli cells, hypothalamus and anterior pituitary, sexual accesory organs
Spermatogenesis
seminiferous tubules and their proliferation, meiotic and differentiation phases
The spermatozoon
anatomy, structure / function,
energy sources, abnormalities
Neuroendocrine control
HPG axis & photoperiodic cues
Male Reproduction
Typical sequence of spermatogenesis in mammalian testis.
Spermatid Differentiation
LECTURE #16
The male HPG axis continuous (non-cyclic) function, pulsatile LH, Leydig and Sertoli cells, hypothalamus and anterior pituitary, sexual accesory organs
Spermatogenesis
seminiferous tubules and their proliferation, meiotic and differentiation phases
The spermatozoon
anatomy, structure / function,
energy sources, abnormalities
Neuroendocrine control
HPG axis & photoperiodic cues
Male Reproduction
Relationship of germ cells to adjacent Sertoli cells.
Spermatid
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LECTURE #16
The male HPG axis continuous (non-cyclic) function, pulsatile LH, Leydig and Sertoli cells, hypothalamus and anterior pituitary, sexual accesory organs
Spermatogenesis
seminiferous tubules and their proliferation, meiotic and differentiation phases
The spermatozoon
anatomy, structure / function,
energy sources, abnormalities
Neuroendocrine control
HPG axis & photoperiodic cues
Male Reproduction
The Golgi phase of spermatid differentiation.
Spermatid
LECTURE #16
The male HPG axis continuous (non-cyclic) function, pulsatile LH, Leydig and Sertoli cells, hypothalamus and anterior pituitary, sexual accesory organs
Spermatogenesis
seminiferous tubules and their proliferation, meiotic and differentiation phases
The spermatozoon
anatomy, structure / function,
energy sources, abnormalities
Neuroendocrine control
HPG axis & photoperiodic cues
Male Reproduction
The Cap, Acrosomal, and Maturation phases of
spermatid differentiation.
The Cap
phase
The Acrosomal
phase
The Maturation
phase
Spermatid
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LECTURE #16
The male HPG axis continuous (non-cyclic) function, pulsatile LH, Leydig and Sertoli cells, hypothalamus and anterior pituitary, sexual accesory organs
Spermatogenesis
seminiferous tubules and their proliferation, meiotic and differentiation phases
The spermatozoon
anatomy, structure / function,
energy sources, abnormalities
Neuroendocrine control
HPG axis & photoperiodic cues
Male Reproduction
The Cap phase of spermatid differentiation.
The Cap
phase Spermatid
LECTURE #16
The male HPG axis continuous (non-cyclic) function, pulsatile LH, Leydig and Sertoli cells, hypothalamus and anterior pituitary, sexual accesory organs
Spermatogenesis
seminiferous tubules and their proliferation, meiotic and differentiation phases
The spermatozoon
anatomy, structure / function,
energy sources, abnormalities
Neuroendocrine control
HPG axis & photoperiodic cues
Male Reproduction
The Acrosomal phase of spermatid differentiation.
The Acrosomal
phase Spermatid
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LECTURE #16
The male HPG axis continuous (non-cyclic) function, pulsatile LH, Leydig and Sertoli cells, hypothalamus and anterior pituitary, sexual accesory organs
Spermatogenesis
seminiferous tubules and their proliferation, meiotic and differentiation phases
The spermatozoon
anatomy, structure / function,
energy sources, abnormalities
Neuroendocrine control
HPG axis & photoperiodic cues
Male Reproduction
The Maturation phase of spermatid differentiation.
The Maturation
phase Spermatid
LECTURE #16
The male HPG axis continuous (non-cyclic) function, pulsatile LH, Leydig and Sertoli cells, hypothalamus and anterior pituitary, sexual accesory organs
Spermatogenesis
seminiferous tubules and their proliferation, meiotic and differentiation phases
The spermatozoon
anatomy, structure / function,
energy sources, abnormalities
Neuroendocrine control
HPG axis & photoperiodic cues
Male Reproduction
Associations of developing germ cells that represent
various stages of the cycle of the seminiferous epithelium.
Spermatid
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Male Reproduction
Associations of developing germ cells that represent
various stages of the cycle of the seminiferous epithelium.
LECTURE #16
The male HPG axis continuous (non-cyclic) function, pulsatile LH, Leydig and Sertoli cells, hypothalamus and anterior pituitary, sexual accesory organs
Spermatogenesis
seminiferous tubules and their proliferation, meiotic and differentiation phases
The spermatozoon
anatomy, structure / function,
energy sources, abnormalities
Neuroendocrine control
HPG axis & photoperiodic cues
Spermatid
LECTURE #16
The male HPG axis continuous (non-cyclic) function, pulsatile LH, Leydig and Sertoli cells, hypothalamus and anterior pituitary, sexual accesory organs
Spermatogenesis
seminiferous tubules and their proliferation, meiotic and differentiation phases
The spermatozoon
anatomy, structure / function,
energy sources, abnormalities
Neuroendocrine control
HPG axis & photoperiodic cues
Male Reproduction
Associations of developing germ cells that represent
various stages of the cycle of the seminiferous epithelium.
Spermatid
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LECTURE #16
The male HPG axis continuous (non-cyclic) function, pulsatile LH, Leydig and Sertoli cells, hypothalamus and anterior pituitary, sexual accesory organs
Spermatogenesis
seminiferous tubules and their proliferation, meiotic and differentiation phases
The spermatozoon
anatomy, structure / function,
energy sources, abnormalities
Neuroendocrine control
HPG axis & photoperiodic cues
Male Reproduction
The head of the bovine spermatozoon.
The
spermatozoon’s
head
LECTURE #16
The male HPG axis continuous (non-cyclic) function, pulsatile LH, Leydig and Sertoli cells, hypothalamus and anterior pituitary, sexual accesory organs
Spermatogenesis
seminiferous tubules and their proliferation, meiotic and differentiation phases
The spermatozoon
anatomy, structure / function,
energy sources, abnormalities
Neuroendocrine control
HPG axis & photoperiodic cues
Male Reproduction
The tail of the bovine spermatozoon.
The
spermatozoon’s
tail
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LECTURE #16
The male HPG axis continuous (non-cyclic) function, pulsatile LH, Leydig and Sertoli cells, hypothalamus and anterior pituitary, sexual accesory organs
Spermatogenesis
seminiferous tubules and their proliferation, meiotic and differentiation phases
The spermatozoon
anatomy, structure / function,
energy sources, abnormalities
Neuroendocrine control
HPG axis & photoperiodic cues
Male Reproduction
The HPG axis in males and females..
LECTURE #16
The male HPG axis continuous (non-cyclic) function, pulsatile LH, Leydig and Sertoli cells, hypothalamus and anterior pituitary, sexual accesory organs
Spermatogenesis
seminiferous tubules and their proliferation, meiotic and differentiation phases
The spermatozoon
anatomy, structure / function,
energy sources, abnormalities
Neuroendocrine control
HPG axis & photoperiodic cues
Male Reproduction
The HPG axis in males and females is affected by
photoperiodic cues, as you will learn in the last lectures.
SCN-CG
SCN-CCG
SCN
Q7
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Comments on your weekly questions
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