850 intelligent-ion-chromatography by Metrohm
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Transcript of 850 intelligent-ion-chromatography by Metrohm
850 Professional IC872 Extension Module858 Professional Sample Processor
Intelligent Ion Chromatography
02
Professional ion chromatography
Metrohm ion chromatography
Metrohm guarantees optimal solutions in ion chroma-
tography based on innovative and creative solutions
through out the last twenty years – with high-tech, many
years of application know-how, Swiss quality standards
and a reasonable pricing policy, both in acquisition and
running costs. Metrohm 850 Professional IC, 872 Exten-
sion Module and 858 Professional Sample Processor are
Swiss Engineered and Swiss Made.
Built-in intelligence
Metrohm IC is ion chromatography from the technology
leader. The 850 Professional IC is the first professional ion
chromatography system with intelligent system compo-
nents:
• Intelligence in the hardware of the 850 Professional IC,
• Intelligence in the MagIC NetTM software,
• Intelligence in the Metrosep iColumns.
Professional IC guarantees excellent results, gapless sys-
tem monitoring, complete traceability of all actions and
the simple operation of even complex procedures.
The 850 Professional IC is an extremely compact system
with all the flexibility of modular design. It adapts itself to
the particular application and is equipped for all future
tasks. Any existing 850 Professional IC system can be
further expanded with 872 Extension Modules. Pro fes-
sional IC also stands for a robust system setup using
high-end components. A long working life with low run-
ning costs is guaranteed.
03
• Highly compact modular system • MagIC NetTM software for intuitive and simple operation
• Comprehensive monitoring and control functions
• Complies with GLP and FDA requirements
• Flexible assembly and extension: from isocratic cation system up to quaternary high-pressure gradient system for anion analysis
• Combined third-generation anion-cation systems
• MISP – Metrohm Inline Sample Preparation – patented and unique sample preparation • Intelligent system components: iPump, iDetector, iColumn, intelligent Dosing Units
• Professional Sample Processor for any required volumes and extensive liquid handling operations
• High-precision Dosino technology
• Broad range of detection possibilities
• Swiss Engineered – Swiss Made
Highlights
Flow path features
The flow path of the 850 Professional IC is metal-free
and biocompatible. Most applications permit Green Che-
mis try without toxic solvents, corrosive eluents or even
cartridges that have to be disposed of as hazardous
waste. Nevertheless the system is 100% solvent-resistant
and withstands even rough surroundings. Eluents are
automatically degassed inline and the MagIC NetTM soft-
ware ensures that they are always fresh.
Automated eluent preparation
The time-consuming manual preparation of the eluents
can be automated. One of the options offered by
Metrohm to realize this is the 845 Eluent Synthesizer,
which prepares eluents from up to four freely selectable
concentrates and one main component. Compared to
the traditional manual eluent preparation, the fully auto-
mated system guarantees precise mixtures and excellent
batch-to-batch reproducibility by simple mouse-click in
the «Mix Control» program.
04 Another option is preparing the eluent directly inline. This
is done by connecting the 849 Level Control and the 800
Dosino to the 850 Professional IC system. Controlled by
MagIC NetTM, the 849 Level Control monitors the eluent
level while the Dosino carries out all the required dosing
and liquid-handling operations. In this case, eluent pre-
paration runs parallel to the determination. The system
allows continuous ion chromatographic analyses over a
month without any manual eluent preparation being
required.
The error-prone and time-consuming eluent pre-
paration can be automated at small additional
cost.
05
Gradients – if necessary
High-pressure or low-pressure gradients are used only
where they are really needed. Gradient form and mixing
are freely selectable: step, linear, convex and concave
gradient functions are available and can be combined.
The 850 Professional IC system is available as a high-
pressure or low-pressure gradient version. Moreover, all
850 Professional IC systems can be operated with the
Dosino Gradient as well.
The high-pressure gradient system can be expanded to
a quaternary gradient system with the 872 Extension
Mo dule.
The low-pressure gradient version is the economic alter-
native to the powerful high-pressure gradient system.
The low-pressure gradient module can also be used for
method development or as eluent selector for the auto-
matic switchover from one application to another.
The gradient systems are available with chemical suppres-
sion, with sequential suppression or without suppres sion,
depending on the requirements. They can be combined
with a broad range of detectors and are suitable for hy -
dro xide as well as carbonate gradients. When working
with sequential suppression and conductivity detection,
the flexibility of the carbonate/hydrogencarbonate elu-
ents can be combined with the low background conduc-
tivity of an hydroxide eluent by the CO2 suppression
app lied after the chemical suppressor.
For gradient applications we recommend the high-ca pa-
city Metrohm Suppressor Module «MSM-HC» to be used
for chemical suppression.
06 Self-monitoring for zero fault tolerance
The intelligent system components monitor and optimize
all functions, which are, if required, documented in an
FDA-com p liant form. The configuration of the system is
as simple as can be imagined, as the components log
themselves in automatically and provide the MagIC NetTM
software with all the relevant information. The way from
the sample to a precise result has become quicker as
even complex sample preparation steps are now carried
out inline and automatically. If necessary, the system will
also automatically optimize sample preconcentration or
sample dilution. The optimal operation of the 850 Pro-
fessional IC and the results are monitored. If a parameter
leaves the predefined range then the user is infor med by
E-Mail or SMS.
Intelligent system
850 Professional IC is a system composed of discrete,
intelligent modules that are optimally matched to one
another. The way from the sample to a precise result has
now become easier, as the system thinks for itself and
makes logical decisions. This prevents operating errors
and improves reliability of results.
The 850 Professional IC is a complex and very efficient
system that can still be operated simply and intuitively
with the MagIC NetTM software. This applies for both
power users with complex applications and complicated
calculations and users who value «one-button opera-
tion». Any user level is possible. Innovation, flexibility and
extremely simple operation result from the intelligence of
the 850 Professional IC, the 872 Extension Module, the
858 Professional Sample Processor and the MagIC NetTM
software.
Intelligent components for an intelligent system
07
The 850 Professional IC system is highly flexible. The prin-
ciple of discrete modules combined into a system means
that users are perfectly prepared to meet ever new and
more demanding challenges. Read more about new
options with the 872 Extension Modules from page 22
on. Moreover, all 850 Professional IC systems can be
com bined with Metrohm’s unique Inline Sample Pre pa-
ra tion techniques (page 13). They provide for a fully
auto mated and reliable analysis of liquid, solid and even
gaseous samples in a single run.
Flexibility in the use of the detection method
Conductivity detection is the most frequently used detec-
tion method in ion chromatography. Metrohm’s iDetec-
tor is a state-of-the-art, powerful and intelligent detec-
tor. If your sam ples require a different detection method,
you can use UV/VIS detection, electrochemical methods
or mass spectroscopic methods as well.
Flexibility in the choice of the separation coulumn
We offer you a wide range of different columns. Depen d-
ing on your application you can choose columns with
various base materials, selectivity, capacity and dimen-
sions. Be sides columns with an inner diameter of
4 mm we can even offer you 2 mm columns to reduce
eluent consump tion. For these «microbore columns» we
have deve loped our new chemical suppressor «MSM-LC».
Superior flexibility
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850 Professional IC system at a glance
091 Housing
All components of the 850 Professional IC are easily
accessible and well laid out. Extensions can be made
at any time – the system grows to meet your require-
ments. The flow path for the application is metal-free
and already preinstalled. The transparent door allows
visual monitoring during the analysis.
2 Eluent transfer
The iPump is a central element of the 850 Professional
IC. Its extremely low pulsation translates into low noise
and consequently in to highest sensitivity of the ana-
lytical system. The iPump optimizes its flow rate on its
own; its memory chip stores all the important infor-
mation.
3 iColumns
The iColumn, the analytical separating column, is the
heart of any application. Thanks to the iColumn tech-
nology, the optimal chromatographic conditions are
stored on a chip, which prevents damage due to ope-
ra tional errors. Moreover, if the iColumn is used on a
different Professional IC system no information is lost
which means that the analytical process is traceable
without any gaps.
4 Column thermostat – hot or cold?
Any temperature between 0 °C and 80 °C is possible.
The analytical columns and the applications determine
how hot or cold the column thermostat has to be. It
can contain up to two iColumns, a further column can
be operated externally at room temperature.
5 Suppression
Sequential or chemical suppression – both allow highly
sensitive analyses due to very low background conduc-
tivity. The 850 Professional IC is now available not only
with the «MSM II» chemical suppressor but also with
the high-capacity «MSM-HC» suppressor or with the
low-capacity «MSM-LC» suppressor. With 0.2 nS/cm
these suppressors have the lowest noise of all suppres-
sors. Metrohm suppressors are extremely robust and
resistant to both solvents and pressure; the reason why
they come with a 10-year warranty.
6 Detection
After their separation on the iColumn the ions pass,
e.g., the intelligent conductivity detector of the 850
Professional IC. The detector transfers the digitized
signal directly to the MagIC NetTM software. Outstanding
temperature stability, a Faraday cage and the latest
generation of DSP – Digital Signal Processing – guaran-
tee highest pre cision. The wide measuring range of the
iDetector of 0...15 000 μS/cm ensures accurate and
precise re sults from traces to percentage – in one
determination.
7 Automation
The 858 Professional Sample Processor is more than
just a sample changer. Equipped with pumps, injection
valve and Dosinos it makes an integral contribution to
Inline Sample Preparation and Liquid Handling. More
than 30 different sample racks are recognized auto-
matically, which means that with respect to their form
and volume very individual sample vessels can be used.
The standard version accommodates 148 samples.
8 Software
Clear symbols, well-laid-out presentation, intuitive ope-
ra tion, «one-button IC»: that‘s MagIC NetTM. Com plete
system monitoring, control cards, comfortable da tabase
functions are additional features of MagIC NetTM, the
intelligent software for con troll ing the 850 Professional
IC and evaluating the data. All 850 Pro fessional IC
instruments, all intelligent Compact IC ins truments,
872 Extension Modules, 858 Pro fess io nal Sample
Processors, 800 Dosinos and iCo lumns are automati-
cally recognized, monitored and controlled.
Suppression
Ion chromatographic analysis, especially that of anions,
uses chemical as well as sequential suppression to reduce
background conductivity and increase sensitivity. Chemical
suppression is based on salts of weakly dissociated acids
(e.g., NaHCO3 / Na2CO3), which produce carbonic acid
sub sequent to cation exchange. The chemical suppres-
sion improves the sensitivity by a factor of 2 to 5.
Sequential suppression
Sequential suppression combines chemical suppression
with Metrohm CO2 Suppression (MCS). «MCS» removes
any carbonate and the CO2 that is produced by the sup-
pressor reaction. This allows the determination of anions
with the flexibility of carbonate/bicarbonate elu ents while
benefitting from a low background conductivity corre-
sponding to that of hydroxide eluents. More over, the
in terference by the carbonate peak during the quantita-
tion of analyte ions is completely eliminated.
Additionally, sequential suppression improves detection
limits and produces a remarkably smaller injection peak,
which in turn improves the determination of the fast-
eluting ions such as fluoride.
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Separation column Metrosep A Supp 5 - 100/4.0 Eluent 3.2 mmol/L Na2CO3/1.0 mmol/L NaHCO3
Flow rate 0.4 mL/min
Nr. Ion Conc. (mg/L) 1 Injection peak – 2 Fluoride 0.04 3 Chloride 7.79 4 Carbonate – 5 Bromide 0.004 6 Nitrate 7.82 7 Sulfate 5.20
Drinking water of Herisau (Switzerland): comparison of chemical (black) and sequential suppression (red)
«MSM II», «MSM-HC» and «MSM-LC»
With the chemical suppressors «MSM II», «MSM-HC» and
«MSM-LC» you can choose exactly the right suppressor
for your application. The «MSM II» is our standard supp-
ressor. The «MSM-HC» was developed for gradient app-
li cations, but can also be used for isocratic applications
with columns with very high capacity. The low capa-
city «MSM-LC» was developed to be used with 2 mm
columns. The very low noise of less than 0.2 nS/cm for
all three suppressors guarantees an extremely high sensi-
tivity of the 850 Professional IC system. The robustness
and resistance against solvents and pressure allows
Metrohm to grant a unique 10-year warranty for these
suppressors.
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Reproducibility of suppression
The state-of-the-art tri-chamber suppressor technology
provides a fresh suppressor chamber for each measure-
ment. The complete regeneration of the chamber after
each sample ensures highly efficient cation exchange –
today, tomorrow and even after years of continuous
operation.
The chromatograms shown below demonstrate the
excellent reproducibility of the measurements with the
Metrohm Suppressor Module:
Ion Fluoride Chloride Nitrite Bromide Nitrate Phosphate Sulfate
Concentration in mg/L 0.25 0.25 0.25 0.25 0.25 0.25 0.25
Relative standard deviation
in % (n = 30) 0.17 0.16 0.38 0.31 0.18 0.46 0.25
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4 5 76
30 injections, separation of the standard anions on the Metrosep A Supp 5 - 100/4.0, eluent 3.2 mmol/L Na2CO3/1.0 mmol/L NaHCO3, fl ow 0.7 mL/min, loop 20 μL, 45 °C, sequential suppression
1 fl uoride, 2 chloride, 3 nitrite, 4 bromide, 5 nitrate, 6 phosphate, 7 sulfate
12
Automation
Automation in ion chromatography not only ensures
opti mal use of the working hours but also improves the
reproducibility of the results. There is no more reason to
waste time on routine tasks such as manual sample in-
troduction or sample preparation. The sample changer
takes over all these functions. We offer you five different
sample changers: The 858 Pro fessional Sample Processor,
the 863 Compact IC Auto sampler, the 889 IC Sample
Center, the 814 USB Sample Processor and the 815
Robotic USB Sample Processor XL.
858 Professional Sample Processor – the perfect
match for the 850 Professional IC
The 858 Professional Sample Processor is more than a
simple sample changer. Equipped with pumps, injection
valve and Dosinos, it can be an integral part of Inline
Sample Preparation and Liquid Handling. More than 30
different sample racks are automatically recognized,
allowing the use of sample vessels that are different in
shape and volume. The standard version of the 858 Pro-
fessional Sample Pro cessor accommodates 148 samples.
The 858 Professional Sample Processor can access up to
999 sample positions. It is also possible to use an external
position for performing tasks such as dilutions or rinsing
the needle.
The 858 Professional Sample Processor handles sample
volumes ranging from 500 μL to 500 mL. Sample trans fer
is carried out by a peristaltic pump or a Dosino. De pend-
ing on the version of the 858 Professional Sample Pro-
cessor, an additional six-port injection valve is available
for sample preparation.
13Metrohm Inline Sample Preparation (MISP)
Crystal clear, clinically pure, no bacteria and no particles:
this would be an ideal sample for ion chromatography.
Unfortunately, apart from the ions to be determined, the
samples often contain large amounts of interfering sub-
stances that make the analysis difficult if not impossible.
Critical samples such as milk, chocolate, caustic soda so -
lutions, biodiesel or strongly loaded waste waters re quire
sample preparation before they can be analyzed by IC.
However, manual sample preparation is time-consuming
and in many cases results in poor reproducibility, in ac cu-
rate results and high costs.
With Metrohm Inline Sample Preparation «MISP», many
of these steps can be automated, significantly increasing
the quality of the results and drastically reducing costs. In
these systems, sample preparation is integrated between
the sample changer and the IC system.
Combined with the 858 Professional Sample Processor,
the 850 Professional IC offers a variety of fully automated
inline sample preparation steps such as Ultrafiltration,
Dia lysis, Preconcentration, Matrix Elimination, Neu trali-
zation, Inline Calibration, intelligent Partial Loop Injection
Technique and Sample Dilution.
Metrohm’s powerful MagIC NetTM chromatography soft-
ware further expands the application range and provides
the ability to make logical decisions such as applying the
automatically calculated dilution factors.
Metrohm Inline Sample Preparation (MISP): These techniques are the key to complete automation of your analyses. Samples are introduced by means of a Sample Processor. Sub -sequently, they are subjected to one of Metrohm’s Inline Sample Preparation techniques. Finally, they are directly injected into an ion chromatograph. This fully automated sequence is the common principle of all MISP techniques.
ProfIC – automated Professional IC systems
Be it the determination of anions at high sample through-
put in analytical service labs or the detection of cations
in ultratrace levels as required in nuclear power plants –
the ProfIC systems offer custom solutions for any IC
application. The website www.professional-ic.com
des cribes more than 20 different system.
Combined with the analytical separation column and the
software, Metrohm ProfIC systems will solve even the
most complex application problems. The three systems
presented here as examples per form the following tasks:
• Routine analysis of particle-containing samples
(ProfIC 2)
• Trace determination of anions in complex matrices
(ProfIC 9) and
• Parallel and independent determination of anions and
cations with intelligent Partial Loop Injection Technique
(ProfIC 15)
For additional information please consult your Metrohm
distributor or the Metrohm website.
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«ProfIC 2» – Professional IC system with Ultrafiltration
Professional IC system for the fully automatic determina-
tion of anions or cations or both with Metrohm Inline
Ultrafiltration. «ProfIC 2» safely masters all routine tasks
in ion chromatography. It is easy to use and extremely
reliable. The system’s components guarantee very high
sensitivity and reproducible results. Particular attention
has been given to long service intervals; these can be
monitored by the intelligent MagIC NetTM software.
«ProfIC 2» is equipped with Metrohm Inline Ultrafiltration,
which reliably removes particles from the sample. This
signi ficantly increases the working life of the column. The
ultrafiltration cell is equipped with a membrane filter with
a pore size of 0.2 μm as standard and is suitable for
samples with a light to medium particle load. Inline Ultra-
filtration works fully automatically saving, for example,
the time-consuming and expensive use of syringe filters.
The ultrafiltration cell is mounted directly on the 858
Professional Sample Processor. The sample is continuously
delivered at a high flow rate. This delays the formation of
a filter cake and increases the working life of the mem-
brane. Crossover is kept below 0.1%. Numerous sample
racks for volumes 0.5...500 mL are available for the 858
Professional Sample Processor. Ultrafiltration requires at
least 5 mL of sample. «ProfIC 2» features in tel li gent sys-
tem components such as iPump and iDe tector and acco-
modates up to three iColumns.
The anion system is additionally equipped with sequen-
tial suppression. This unique combination of chemical and
downstream CO2 suppression allows to achieve very low
detection limits. The flexibility of the carbonate eluent is
complemented by the low background conductivity.
The «ProfIC 2» system is your reliable partner, both in
routine operation and in R&D.
Applications
• Determination of cations or anions or combined
determination of anions and cations
• Routine applications
• Analysis of samples containing interfering particles,
algae or bacteria, for example:
- Drinking water
- Process water
- Waste water
- Extracts
- Digestion solutions
- Diluted fruit and vegetable juice
17
Flowsheet ProfIC 2 Anion
ProfIC 2 Anion
Schematic of ultrafi ltration cell
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«ProfIC 9» – Professional IC system for trace analysis with Inline Calibration, Sample Preconcentration and Matrix Elimination
Professional IC system for ultratrace analysis of anions or
cations in complex matrices. «ProfIC 9» with Metrohm
Inline Sample Preconcentration and Matrix Elimination
allows chromatography unaffected by matrix influences
and guarantees that the analytical column has a long
working life. Metrohm Inline Calibration permits very low
concentrations – in the ppt range (ng/L) – to be reliably
calibrated using a single standard of higher concentra-
tion – in the ppb range (μg/L).
The sample is transferred to the preconcentration col-
umn fully automatically and with high precision by the
intelligent 800 Dosino. The anions or cations are retained.
The matrix can be removed in a rinsing step. The clean
sample is then transferred to the IC system.
The 850 Professional IC – Prep 2 is equipped with an
additional valve for liquid handling. The peristaltic pump
transfers the standard. The intelligent MagIC NetTM soft-
ware controls and monitors the system.
Applications
• Ultratrace analysis for anions and cations in
- Nuclear power plants
- Conventional power plants
- Semiconductor industry
• Trace analysis in organic solvents
• Quality control of fine chemicals
Calibration and calculation of the results as a function of
preconcentration volume is also carried out by the MagIC
NetTM software. Even if complex procedures are involved,
operating the system remains perfectly easy.
The anion system is additionally equipped with sequen-
tial suppression. Very high sensitivity is achieved by this
unique combination of chemical and downstream CO2
suppression. The flexibility of the carbonate eluent is
complemented by the low background conductivity.
Elimination of the carbonate interference is a particular
benefit when using the preconcentration technique.
The 858 Professional Sample Processor provides for
sample delivery. Numerous sample racks for volumes
0.5...500 mL are available. Typical preconcentration
vo lumes are between 0.5 and 100 mL.
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ProfIC 9 Anion
Flowsheet ProfIC 9 Anion
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«ProfIC 15» – Professional IC system for intelligent Partial Loop Injection Technique
Professional IC system for the fully automated determina-
tion of anions, cations or anions and cations with Metrohm
intelligent Partial Loop Injection Technique «MiPT».
Metrohm intelligent Partial Loop Injection Technique allows
the injection of variable sample volumes. This en ables the
injection of concentrated samples without pre vious dilu-
tion as well as multipoint calibration using a single stand-
ard solution. «ProfIC 15» safely masters all routine tasks
in ion chromatography.
With this system, samples of widely different concentra-
tions such as ultrapure water and drinking water can
be injected. «MiPT» ensures that the injected volume is
app ro priate to the sample concentration. The efficient
rinsing procedure ensures that the carryover from sample
to sample is practically zero. The system is easy to operate
and highly reliable.
The system components guarantee very high sensitivity
and reproducibility of the results. Particular attention has
been given to long service intervals, which can be moni-
tored by the MagIC NetTM software.
The anion system is equipped with sequential suppres-
sion. The unique combination of chemical and down-
stream CO2 suppression results in very low detection
limits and allows to benefit from the flexibility of carbon-
ate eluents and a low background conductivity corres-
ponding to that of hydroxide eluents.
Sample transfer is carried out by the 800 Dosino. The
high-precision liquid handling enables simple and highly
reproducible Partial Loop Injections. This translates into
extremely accurate results and an excellent linearity. An
automated calibration covering a concentration ratio of
1:10’000 can easily be carried out with just one standard.
Numerous sample racks for volumes 0.5...500 mL are
available for the 858 Professional Sample Processor. Due
to its flexibility, the «ProfIC 15» system is your reliable
partner, both in routine operation and in R&D.
Applikations
• Determination of anions, cations or combined
determination of anions and cations
• Routine applications
• R&D
• Trace analysis
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Flowsheet ProfIC 15 AnCat – the ideal system for the parallel analysis of anions and cations
ProfIC 15 AnCat
22
872 Extension Module
872 Extension Module IC Pump
The 872 Extension Module IC Pump combines an IC high-
pressure pump «iPump» with an eluent degasser, a purge
valve, an inline filter and a pulsation absorber.
With the 872 Extension Module IC Pump, an isocratic
Professional IC system can be expanded up to a quater-
nary high pressure gradient system.
872 Extension Module Sample Prep
The 872 Extension Module Sample Prep comprises a
dual-channel peristaltic pump for transferring any type of
liquid in the low-pressure range and a six-port injection
valve that can be used both in the high-pressure and in
the low-pressure range of the Professional IC system.
The 872 Extension Module Sample Prep expands the
possi bilities of Inline Sample Preparation and Liquid Hand-
ling. Additional flexibility results from implementing column
selection systems, cutting techniques or multi di men sional
IC applications.
The 872 Extension Modules enhance the capabilities of
the 850 Professional IC family.
The flexibility of the 850 Professional IC allows to tailor
the system to the application according to your needs.
Determination of anions and cations in parallel for one
application and a quaternary gradient for another appli-
cation are all simple tasks.
Up to three 872 Extension Modules can be connected to
an 850 Professional IC instrument. The 872 Extension
Modules are controlled by the user-friendly MagIC NetTM
software, whose intelligence and ease of method con-
figuration greatly contribute to the flexibility of the over-
all system.
872 Extension Module Liquid Handling
The 872 Extension Module Liquid Handling features a
dual channel peristaltic pump for transferring all kinds of
liquids in the low-pressure range, a six-port injection valve
and a ten-port selection valve.
The 872 Extension Module Liquid Handling extends the
capabilities of Inline Sample Preparation and Liquid Hand-
ling thus extending the field of possible applications. For
example, the 872 Extension Module Liquid Handling can
be used to mix solutions, set the pH value of a sample or
carry out pre-column derivatization reactions.
Moreover, the ten-port valve can be used as a selection
valve for the automated supply of all kinds of liquid samples.
23
872 Extension Module IC Module
The 872 Extension Module IC Module enables the instal-
lation of an additional IC high-pressure pump «iPump»
with eluent degasser, purge valve, inline filter, pulsation
absorber and six-port injection valve in an 850 Professional
IC system.
Due to the 872 Extension Moudle IC Module, the 850
Professional IC can be equipped with an additional analy-
tical channel. Thus, applications like parallel analysis of
anions and cations using a low pressure gradient or Inline
Neutralization become feasible. Moreover, an additional
analytical channel equipped with an alternative detector,
e.g., a UV/VIS detector or an amperormetric detector,
be comes also possible.
872 Extension Module Supperssion
The 872 Extension Module Suppression is equipped with a
dual-channel peristaltic pump and a Metrohm Supp ressor
Module. Any of the three suppressor rotors «MSM II»,
«MSM-HC» or «MSM-LC» can be chosen, depending on
the requirements.
Toghether with one of the mentioned suppressor rotors,
the 872 Extension Module Suppression enables the in s-
tallation of an additional chemical suppressor in an 850
Professional IC system. Thus, systems with two chemi cally
suppressed analytical channels become feasible.
The 872 Extension Module Suppression can also be
equip p ed with a Sample Preparation Module «SPM»-rotor
permitting the combination of Inline Neutrali zations with
various configurations of 850 Systems.
872 Extension Module Suppression – MCS
Besides a dual-channel persistaltic pump and a Metrohm
Suppressor Module, the 872 Extension Module Supp-
ression – MCS features a CO2 Suppressor «MCS». Any of
the three suppressor rotors «MSM II», «MSM-HC» or
«MSM-LC» may be chosen, depending on the requirements.
The 872 Extension Module Suppression – MCS enables
the installation of an additional sequential suppressor in
an 850 Professional IC system. Thus, systems with two
complete anion channels can be configured.
24
Technical information
General Professional ion chromatography system
• Compact modular system
• Intelligent system components
• Integral Metrohm Inline Sample Preparation «MISP»
• Metal-free flow path
• 3-year warranty
Intelligent system Intelligent technology is incorporated in the following system components,
components among others:
• iPump • iDetector
• iColumn • 800 Dosino
Metrohm Inline Sample The following optional components can be integrated:
Preparation «MISP» • Ultrafiltration • Neutralization
• Dialysis • Matrix Elimination
• Dilution • Calibration
• Preconcentration • Partial Loop Injection Technique
Eluent and sample Organic modifier 0...100% (no PFCs [perfluoro carbon compounds])
degassing Material Teflon AFTM
High-pressure pump Serial dual-piston pump with two valves and flow-range-optimized intelligent pump
heads
Flow rate 0.001...20 mL/min
Reproducibility <0.1% deviation from the set value
Pulsation <1% (typically)
Injection valve Injection volume:
Internal loop 0.25, 1 μL
External sample loop 1.5, 5, 10, 20, 100, 250, 1000 μL
Column thermostat Temperature range 0...80 °C (ambient temperature -20...+50 °C)
Stability <0.05 °C
Suppressors «MSM II», «MSM-HC» or «MSM-LC» Metrohm Suppressor Modules for chemical
suppression
Type «Micro Packed Bed» suppressor
Design 3 cartridges in a rotor
Regeneration 100 mmol/L H2SO4
Rinsing demineralized water
Transport of solutions Peristaltic pump or 800 Dosino
Organic modifier 0...100%
Warranty 10 years
«MCS» Metrohm CO2 Suppressor
Type CO2 removal with Teflon AFTM technology
Organic modifier 0...100% (no PFCs [perfluoro carbon compounds])
25 Conductivity detector Conductivity detector Intelligent high-performance conductivity detector
Measuring principle DSP – Digital Signal Processing
Measuring range 0...15 000 μS/cm – without range switching
Max. back pressure 5 MPa
Temperature 20...50 °C in steps of 5 °C
Temperature stability <0.001 °C
Cell volume 0.8 μL
Cell constant 16.7/cm (nominal), calibrated value is stored in
iDetector, can be recalibrated
Measuring frequency 10 Hz
Resolution 4.7 pS/cm
Electronic noise <0.1 nS/cm (at 1 μS/cm)
Baseline noise <0.2 nS/cm (e.g. A Supp 5, standard conditions)
Peristaltic pumps Speed 0...42 rpm in steps of 6 rpm
Direction clockwise and counter-clockwise
Gradients Type high-pressure: binary, ternary, quaternary
low-pressure: binary, ternary
Dosino: binary, ternary, quaternary, quinary
Form step, linear, convex*, concave* (*...for high- and low-pressure gradients)
Professional Sample Processor
Racks Automatic sample rack recognition (individual adaptations of the sample rack
to accommodate specific vessel forms and sizes are possible)
Sample volume 0.5...500 mL (standard volume: 11 mL)
Positions 999 rack positions and four external positions are accessible
Control Metrodata MagIC NetTM
Connections 850 Professional IC 858 Professional Sample Processor
Leak sensor 1 USB upstream 3 (hub)
Detectors 2 USB downstream 1 (PC)
USB upstream 2 (hub) MSB (Metrohm Serial Bus) 3
USB downstream 1 (PC) Membrane pumps 2
MSB (Metrohm Serial Bus) 2 Swing Head 1
Connection of peripheral instruments: 858 Professional Sample Processor via USB;
800 Dosino, 801 Magnetic Stirrer, 6.2148.010 Remote Box, etc. via MSB
Dimensions in mm (W/H/D) 850 Professional IC 858 Professional Sample Processor
365/642/380 280/730/500
872 Extension Module
365/131/380
26
Ordering information
ProfIC systemsProfessional IC system for automated ion chromatography (ProfIC 1 – Anion, ProfIC 1 – Cation and ProfIC 1 – AnCat)Professional IC system with Inline Ultrafiltration (ProfIC 2 – Anion, ProfIC 2 – Cation and ProfIC 2 – AnCat)Professional IC system with Inline Dialysis (ProfIC 3 – Anion and ProfIC 3 – Cation)Professional IC system with Inline Dilution (ProfIC 4 – Anion and ProfIC 4 – Cation)Professional IC system with Inline Preconcentration (ProfIC 5 – Anion and ProfIC 5 – Cation)Professional IC system with Inline Dilution and Ultrafiltration (ProfIC 6 – Anion and ProfIC 6 – Cation)Professional IC system with Inline Dilution and Dialysis (ProfIC 7 – Anion and ProfIC 7 – Cation)Professional IC system with Inline Preconcentration and Matrix Elimination (ProfIC 8 – Anion and ProfIC 8 – Cation)Professional IC system for trace analysis with Inline Calibration, Preconcentration and Matrix Elimination (ProfIC 9 – Anion und ProfIC 9 – Cation)Professional IC system with Inline Preconcentration, Matrix Elimination and Neutralization (ProfIC 10 – Anion) Professional IC system for trace analysis with Inline Calibration, Preconcentration, Matrix Elimination and Neutralization (ProfIC 11 – Anion) Professional IC Gradient System (ProfIC 12 – Anion) Professional IC system for intelligent Partial Loop Injection Technique (ProfIC 15 – Anion, ProfIC 15 – Cation and ProfIC 15 – AnCat)
Software MagIC NetTM
6.6059.222 MagIC NetTM 2.2 Professional6.6059.208 MagIC NetTM 2.X Professional upgrade to Multi – 3 licenses6.6059.223 MagIC NetTM 2.2 Multi – 3 licenses6.6059.001 MagIC NetTM Multi – 1 additional license6.6059.002 MagIC NetTM Multi – 5 additional licenses6.6059.003 MagIC NetTM Multi – 10 additional licenses
850 Professional IC instruments2.850.1010 850 Professional IC Cation2.850.1030 850 Professional IC Cation – Prep 12.850.1050 850 Professional IC Cation – Prep 22.850.1210 850 Professional IC Cation – LP Gradient2.850.1220 850 Professional IC Cation – Gradient2.850.2010 850 Professional IC Anion*2.850.2030 850 Professional IC Anion – MCS*2.850.2050 850 Professional IC Anion – MSM-HC*2.850.2070 850 Professional IC Anion – MSM-HC – MCS*2.850.2110 850 Professional IC Anion – MCS – Prep 1*2.850.2120 850 Professional IC Anion – MSM-HC – MCS – Prep 1*2.850.2140 850 Professional IC Anion – MSM-HC – MCS – Prep 2*2.850.2150 850 Professional IC Anion – MCS – Prep 2*2.850.2180 850 Professional IC Anion – MSM-HC – MCS – Prep 3*2.850.2190 850 Professional IC Anion – MCS – Prep 3*2.850.2210 850 Professional IC Anion – MCS – LP Gradient*2.850.2220 850 Professional IC Anion – MCS – Gradient*2.850.2230 850 Professional IC Anion – MSM-HC – MCS – LP Gradient*
272.850.2240 850 Professional IC Anion – MSM-HC – MCS – Gradient*2.850.2250 850 Professional IC Anion – MSM-HC – LP Gradient*2.850.2260 850 Professional IC Anion – MSM-HC – Gradient*2.850.3000 850 Professional IC AnCat – non-suppressed2.850.3010 850 Professional IC AnCat 2.850.3030 850 Professional IC AnCat – MCS2.850.3040 850 Professional IC AnCat – MSM-HC – MCS
* ... 850 Professional IC instruments for anion analysis can also be used for cation analyis.
872 Extension Module 2.872.0010 872 Extension Module IC Pump2.872.0030 872 Extension Module IC Module 2.872.0050 872 Extension Module Sample Prep2.872.0060 872 Extension Module Liquid Handling2.872.0110 872 Extension Module Suppression2.872.0120 872 Extension Module Suppression – MCS
850 Professional IC – detectors (to be ordered separately)2.850.9010 850 Professional IC Detector «iDetector»2.887.0010 887 Professional UV/VIS Detector
850 Professional IC – accessories6.5330.000 IC equipment for Dialysis6.5330.010 IC equipment for Ultrafiltration6.5330.020 IC equipment for Sample Dilution6.5330.040 IC equipment for Liquid Handling with the Dosino6.5330.050 IC equipment for Dosino Gradient6.5334.000 4-port-stator and 0.25-μL-rotor equipment6.5334.010 4-port-stator and 1.0-μL-rotor equipment
Automation2.858.0010 858 Professional Sample Processor 2.858.0020 858 Professional Sample Processor – Pump2.858.0030 858 Professional Sample Processor – Pump – Injector2.863.0010 863 Compact IC Autosampler2.889.0010 889 IC Sample Center2.889.0020 889 IC Sample Center – cool
858 Professional Sample Processor – accessories6.2041.440 Standard sample rack 148 x 11 mL + 3 x 300 mL6.2041.760 Sample rack 54 x 11 mL + 1 x 300 mL6.2041.390 Sample rack 16 x 120 mL6.2041.480 Sample rack 159 x 2 mL + 3 x 300 mL6.2743.050 PP sample vessels (11 mL); 2000 pieces6.2743.040 PP sample vessels (2.5 mL); 2000 pieces6.2743.070 PP stopper with perforation for sealing the sample vessels; 2000 pieces6.5330.030 IC equipment rinsing station for 858 Sample Processor
Liquid Handling2.800.0010 800 Dosino 2.801.0010 801 Magnetic Stirrer2.849.1030 849 Level Control for Inline Eluent Preparation6.3032.210 Dosing Unit 10 mL6.2070.000 Footprint Extension to 801 Stirrer
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