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Name of

Drug

Action Indication Contraindication Adverse Reaction Nursing

responsibilities

Generic

name:

Oxacillin

Dosage:

500mg tiv

Bactericidal:

inhibits cell

wall synthesis

of sensitive

organisms

causing cell

death

Infections due to

penicillinase-

producing

staphylococci; may

be used to initiate

treatment when a

staphylococci

infection is

suspected

Contraindicatedwith allergies to

penicillins,

cephalosporins, or

other allergens.

Use cautiously with

renal disorders,

pregnancy,

lactation

Lethargy Seizures Stomatitis nausea,

vomiting,

diarrhea, abdominal pain, anemia fever, wheezing,

anaphylaxis

pain, phlebitis,thrombosis at

injection site

Side effectsmay be

experienced,

such as: upset

stomach,

nausea,

diarrhea (small

frequent

meals), mouth

sores (performfrequent

mouth care)

and pain at

injection site.

Reportdifficulty of

breathing,

rashes, severediarrhea,

severe pain at

injection site,

mouth sores.

Finish entirecourse of

therapy as

prescribed.

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Name of

Drug

Action Indication Contraindication Adverse Reaction Nursing

responsibilities

Generic

name:

Paracetamol

Brand name:

Biogesic

Dosage: 500

mg PO

Decreases

fever by a

hypothalamic

effect leading

to sweating

and

vasodilation

Inhibits

pyrogen

effect on the

hypothalamic-heat-

regulating

centers

Inhibits CNS

prostaglandin

synthesis with

minimal

effects on

peripheral

prostaglandin

synthesis.

For fever RenalInsufficiency

Anemia Minimal GI upset. Hemolytic Anemia Neutropenia Thrombocytopenia Pancytopenia Jaundice Glissitis Drowsiness Liver Damage

Monitor CBC,liver and renal

functions.

Assess for fecaloccult blood and

nephritis.

Avoid using OTCdrugs with

Acetaminophen.

Take with food ormilk to minimize

GI upset.

Report N&V.cyanosis,

shortness of

breath and

abdominal pain

as these are signs

of toxicity.

Report abdominalpain, jaundice,

dark urine,

itchiness or clay-

colored stools.

Phenmacetin maycause urine to

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become dark

brown or wine-

colored..

This drug is notfor regular use

with any form

of liver disease.

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Name of Drug Action Indication Contraindication Adverse Reaction Nursing

responsibilities

Generic

name:

Ceftriaxone

Brand name:

Rocephin

Dosage:2gm

TIV OD

Inhibits

bacterial cell

wall

synthesis,

rendering cell

wall

osmotically

unstable,

leading to cell

death

Treatment of LRIT

(e.g. bronchitis,

pneumonia,

bronchopneumonia,

emphysema, lung

abscess), skin and

soft tissue

infections

Contraindicated to

patient with

hypersensitivity to the

drug.

Phlebitis Rash diarrhea, Vomiting Pain Elevated

temperature

Use cautiouslyin client with a

history of

sensitivity to

penicillin.

Obtain aspecimen for

culture and

sensitivity test

before first

dose. Therapymay begin

pending result.

Teach client toreport sore

throat, bruising,

bleeding and

joint pain.

Advice client towatch out forperineal itching,

fever, malaise,

redness, pain,

swelling, rash

diarrhea.

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Name of Drug Action Indication Contraindication Adverse Reaction Nursing

responsibilities

Generic

name:Omeprazole

Brand

name:prilosec

Dosage: 40mg +

PNSS OD

Omeprazole,

like other

proton-pump

inhibitors,

blocks the

enzyme in the

wall of the

stomach that

produces

acid. By

blocking the

enzyme, the

production of

acid is

decreased,

and thisallows the

stomach and

esophagus to

heal.

*Severe erosive

esophagitis

*poorly responsive

gastroesophageal

reflux disease.

*GI Upset

Contraindicated to

patient with

hypersensitivity to the

drug.

diarrhea nausea Vomiting Headaches Rashes Dizziness Weakness leg cramps Water retention

occurs

infrequently.

Asses patients

condition before

starting the therapy.

*Be alert to adverse

reaction.

*If GI reaction occur

monitor patients

hydration

*Give 30 minutes

before meals

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Name of

Drug

Action Indication Contraindication Adverse Reaction Nursing responsibilities

Generic

name:

Lactulose

Brand

name:

Constulose

Dosage:

30ml OD

Produces an

osmotic effect

in the colon

resulting

distention

promotes

peristalsis. Also

decrease blood

ammonia,

probably as a

result of

bacterial

degradation,

which

decreases the

pH of colon

contents.

constipation Contraindicated in

patients on low

galactose diet.

Abdominalcramps

Nausea Vomiting Diarrhea Flatulence

To minimize sweet

taste, dilute with water

or fruit juice or give

with food.

Monitor serumsodium level for

possible

hypernatremia,

especially when

giving a higher

dose to treat

hepaticencephalopathy.

inform clientabout adverse

reactions and

tell her to notify

doctor if they

become

bothersome or

if diarrhrea

occur.

store at roomtemperature,

preferably

below 89o F or

30O C. dont

freeze.

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Name of

Drug

Action Indication Contraindication Adverse Reaction Nursing

responsibilities

Generic

Name:

Mannitol

Brand Name:

Osmitrol

Increases

osmotic

pressure of

plasma in

glomerular

filtrate,

inhibiting

tubular

reabsorption

of water

andelectrolytes

(including

sodium and

potassium).These actions

enhance water

flow from

various

tissuesand

ultimately

Test dose for marked

oliguria or suspected

inadequate renal

function, prevent

acute renal failure

during

cardiovascular and

other surgeries, acute

renal failure, to

reduce intracranial

pressure and brain

mass,reduce

intraocular pressure,

to promote dieresis indrug toxicity,

irrigation during

transurethralresection

of prostate.

progressiveheart failure

pulmonarycongestion,

renal damage,

or renaldysfunction

severepulmonary

congestion or

pulmonary

edema

and severedehydration.

dizziness,headache

seizures chest pain hypotension,

hypertension,tachycardia,

thrombophlebiti

s,

blurred vision rhinitis nausea

vomiting,

diarrhea

dry mouth polyuria, urinary

retention,

Assess skinturgor,

mucous

membranes

and mental

status before

administration

of drug.

Assess signsfor electrolyte

imbalance.

Monitor Vitalsigns including

central venous

pressure and

output.

Store at roomtemperature.

Be alert foradverse

reactions and

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decrease

intracranial

and intraocular

pressures.

drug

interactions.

Monitor IV sitecarefully toavoid

extravasations

and tissue

necrosis

Do not add toother IV

solutions or

mix with other

medications

Watch forexcessive fluid

loss and signs

and symptoms

of

hypovolemia

and

dehydration.