4.2 Overview of Photosynthesis•Set up Cornell Notes on pg. 61

•Topic: 5.3 Regulation of the Cell Cycle

•Essential Question:

1. How do cancer cells differ from healthy cells?

2.1 Atoms, Ions, and Molecules

5.3 Regulation of the Cell Cycle

1. How do cancer cells differ from healthy cells?

Key concept: Cell Cycle regulation is necessary for healthy growth

4.2 Overview of Photosynthesis

Pg. 60 Cancer Circle Map

Cancer

Cancer Multi-Flow Map

5.3 Regulation of the Cell Cycle

KEY CONCEPTCell cycle regulation is necessary for healthy growth.

5.3 Regulation of the Cell Cycle

• Please create a circle map identifying anything you know about cancer, types of cancer, treatments, causes of cancer

Cancer

5.3 Regulation of the Cell Cycle

Cancer

Lung cancer

Smoking

drinking

Chewing tobacco

Sun exposureRadiation exposure

CAUSES

TYPES

Breast cancer

Skin cancer

Liver cancerleukemia

WHAT I KNOW

Can be deadlySome are curable

Some can be prevented

Thyroid cancer

5.3 Regulation of the Cell Cycle

Discussion Question…

• Have you ever watched a movie in which people play with the elements of nature? These movies are usually “scary” and

involve things getting “out of control”.

• List a few movies where this occurs:

– Tell me the name of the movie

– What happens?

5.3 Regulation of the Cell Cycle

“OUT OF CONTROL”

5.3 Regulation of the Cell Cycle

• Growth factors are proteins that stimulate cell division.

– Most mammal cells form a single layer in a culture dish and stop dividing once they touch other cells.

5.3 Regulation of the Cell Cycle

– a normal feature of healthy organisms– caused by a cell’s production of self-destructive

enzymes– occurs in

developmentof infants

webbed fingers

• Apoptosis is programmed cell death.

5.3 Regulation of the Cell Cycle

• Cancer is the common name for a class of diseases characterized by uncontrolled cell division.– Arises when regulation of the cell cycle breaks down– Continue to divide, may lead to uncontrolled growth

5.3 Regulation of the Cell Cycle

• Cancer cells do not carry out necessary functions.

• Cancer cells come from normal cells with damage to genes involved in cell-cycle regulation.

5.3 Regulation of the Cell Cycle

• Cancer cells form disorganized clumps called tumors.

cancer cellbloodstream

normal cell

– Benign tumors remain clustered and can be removed.– Malignant tumors metastasize, or break away, and can

form more tumors.

5.3 Regulation of the Cell Cycle

• Carcinogens are substances known to promote cancer.– Ex: cigarettes, formaldehyde, pesticides, smog, etc….

5.3 Regulation of the Cell Cycle

• Standard cancer treatments typically kill both cancerous and healthy cells.

5.3 Regulation of the Cell Cycle

Cancer treatments

Radiation therapy

chemotherapy

Surgery to remove the cancer

5.3 Regulation of the Cell Cycle

• Please add new information to your circle map

Cancer

5.3 Regulation of the Cell Cycle

Homework/Classwork: Multi-Flow Map of Cancer

Cancer

Causes Effects, outcome