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K 812

04 Sept 07

Cardiac Ultrastructure

4 Sept 07 2

K 812 Website

www.sfu.ca/~tibbits/courses/K812

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E-C coupling in mammalian heart

4 Sept 07 7

Cardiac Structure•Gross structure

•MRI, Echocardiography, PET etc

•Ultrastructure•Electron microscopy

•Transmission (TEM)

•Scanning (SEM)

•Tomography

•Light microscopy

•Wide field

•Confocal

4 Sept 07 8

Cardiac Ultrastructure

Electron microscopy

Advantages:

High resolution (sub m)

Disadvantages:

Tissues fixed – non living

Labour and skill intensive preparation

Expensive equipment

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