3D Mammography
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Transcript of 3D Mammography
3D Mammography3D Mammography
Ernesto Coto Sören Grimm Ernesto Coto Sören Grimm Stefan Bruckner M. Eduard GröllerStefan Bruckner M. Eduard Gröller
Institute of Computer Graphics and AlgorithmsInstitute of Computer Graphics and AlgorithmsVienna University of TechnologyVienna University of Technology
TU WienInstitute of Computer Graphics and Algorithms3D Mammography
MotivationMotivation Breast cancer is the second leading cause of
cancer deaths in women today X-Ray Mammography is currently the primary
method of early detection Interpretation of Mammograms is difficult Radiologists often use CAD for prompting
X-Ray Mammography
TU WienInstitute of Computer Graphics and Algorithms3D Mammography
MotivationMotivation Capability of X-ray mammography is limited by its
2D representation Other imaging modalities can obtain a full 3D
representation of the breastRendering of MRI Mammographyshowing cancer
TU WienInstitute of Computer Graphics and Algorithms3D Mammography
IntroductionIntroduction CancerCancer is a disease that causes cells in the body is a disease that causes cells in the body
to divide and reproduce abnormally without controlto divide and reproduce abnormally without control
Breast cancerBreast cancer refers to a malignant tumor that refers to a malignant tumor that has developed from breast cellshas developed from breast cells
TU WienInstitute of Computer Graphics and Algorithms3D Mammography
Breast AnatomyBreast Anatomy The breast has two main components: glandular The breast has two main components: glandular
tissue and connective tissuetissue and connective tissue
TU WienInstitute of Computer Graphics and Algorithms3D Mammography
Suspicious Regions Suspicious Regions CalcificationsCalcifications are tiny calcium deposits within the are tiny calcium deposits within the
breast tissuebreast tissue MicrocalcificationsMicrocalcifications MacrocalcificationsMacrocalcifications
MassesMasses SolidSolid Liquid (Cyst)Liquid (Cyst)
TU WienInstitute of Computer Graphics and Algorithms3D Mammography
Doctors QuestionsDoctors Questions Is there a tumor in the breast?Is there a tumor in the breast? Is the tumor benign or malignant?Is the tumor benign or malignant? Is it a mass, a cyst or a microcalcification cluster?Is it a mass, a cyst or a microcalcification cluster? What’s the location of the tumor?What’s the location of the tumor? What’s the size of the tumor?What’s the size of the tumor? How dense is the breast?How dense is the breast? What’s the extension of the cancer?What’s the extension of the cancer?
TU WienInstitute of Computer Graphics and Algorithms3D Mammography
Imaging TechnologiesImaging Technologies X-Ray MammographyX-Ray Mammography Magnetic Resonance Imaging (MRI)Magnetic Resonance Imaging (MRI) Full-Field Digital MammographyFull-Field Digital Mammography Nuclear ImagingNuclear Imaging TomosynthesisTomosynthesis UltrasoundUltrasound
X-Ray MRI
Ultrasound
TU WienInstitute of Computer Graphics and Algorithms3D Mammography
Dynamic Contrast Enhanced MRIDynamic Contrast Enhanced MRI A tumor is usually well vascularized due to its A tumor is usually well vascularized due to its
strong growthstrong growth
The absorption of contrast-medium in suspicious The absorption of contrast-medium in suspicious regions is perceptibleregions is perceptible
Without contrast
With contrast
Intravenous catheter
TU WienInstitute of Computer Graphics and Algorithms3D Mammography
Study of contrast agent’s flowStudy of contrast agent’s flow Type I: steady enhancement (straight or curved) Type II: plateau of signal intensity Type III: washout of signal
Possible malignancy
Benign lesion
Strongly suggest malignancy
TU WienInstitute of Computer Graphics and Algorithms3D Mammography
Answers using DCE-MRIAnswers using DCE-MRI Is there a tumor in the breast?Is there a tumor in the breast?
Segment the contrast agentSegment the contrast agent Is the tumor benign or malignant?Is the tumor benign or malignant?
Study of contrast agent’s flowStudy of contrast agent’s flow Extract features and use them to classify the Extract features and use them to classify the
tumorstumors Is it a mass, a cyst or a microcalcification cluster?Is it a mass, a cyst or a microcalcification cluster?
Quantify segmented region(s)Quantify segmented region(s) What’s the location of the tumor?What’s the location of the tumor?
Estimate position of tumor’s centerEstimate position of tumor’s center
TU WienInstitute of Computer Graphics and Algorithms3D Mammography
Answers using DCE-MRIAnswers using DCE-MRI What’s the size of the tumor?What’s the size of the tumor?
Calculate largest tumor diameterCalculate largest tumor diameter Calculate volume based on segmented voxelsCalculate volume based on segmented voxels
How dense is the breast?How dense is the breast? Segment glandular tissue + quantificationSegment glandular tissue + quantification
TU WienInstitute of Computer Graphics and Algorithms3D Mammography
Answers using DCE-MRIAnswers using DCE-MRI What’s the extension of the cancer?What’s the extension of the cancer?
Classify as invasive or non-invasiveClassify as invasive or non-invasive
Non-invasive Invasive
TU WienInstitute of Computer Graphics and Algorithms3D Mammography
CAD for DCE-MRICAD for DCE-MRI
“Interactive Detection and Visualization of Breast Lesions Using Dynamic Contrast Enhanced (DCE) MRI Volumes“, Computerized Medical Imaging and Graphics, Elsevier, July 2004.
TU WienInstitute of Computer Graphics and Algorithms3D Mammography
QuestionsQuestions
TU WienInstitute of Computer Graphics and Algorithms3D Mammography
SuggestionsSuggestions How can me make this better???How can me make this better???