3d-Human Digestive System 2009

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    Human Digestive

    System

    Chapter 10.2

    Ms. Ho

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    Ingestion

    Digestion Absorption

    Excretion

    Functions of the Digestive

    System

    *Note: alternate terms for the Digestive Tract are GI

    (gastrointestinal) Tract & Alimentary Canal

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    Mouth and Oral Cavity

    Mouth opens to the

    Oral Cavity

    Teeth

    Salivary Glands

    Tongue

    Other Structures:

    uvula, soft palate,

    hard palate, tonsils

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    Teeth Structure & Function

    Mechanical digestion

    OR breakdown of food

    Incisors: bite & cut

    Canines: tearing &

    shreading

    Bicuspids/Premolars:

    pierce & tear Molars: crush & grind

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    How are teeth modified in

    organisms?

    Carnivore Herbivore Omnivore

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    Salivary Glands

    Food is mixed with saliva that is produced by

    3 pairs of salivary glands

    Parotid (largest)

    Sublingual (smallest)

    Submandibular

    Uses ducts (tubular

    canals) to transportsecretions to mouth

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    Saliva

    Presence of food triggers nervous reflex insalivary glands release saliva via ducts

    Saliva is 99% water, mucus (glycoprotein)& enzymes (i.e. salivary amylase)

    Function:

    protects lining of oral cavity from abrasion &lubricates food for easier swallowing

    chemical digestion: amylase breaks downpolysaccharide (amylose maltose)

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    Functions of the Tongue

    Helps mix saliva &food together

    Positions food on

    molars for chewing Moves food around

    until it forms a bolus(food ball) & pushes

    it back to pharynx Primary organ for

    taste

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    Tongue & Taste Buds

    Muscle containing

    papillae pimple-like

    structure on upper

    surface of tongue thathouses the taste buds

    4 sensory tastes:

    Sweet

    Salty Sour

    Bitter

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    Location of Taste Buds

    Q: Are you a

    Super-taster?

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    Other Oral Cavity structures

    Uvula: flap of tissue covering nasal cavity

    when swallowing food

    Tonsils: lymphoid tissue on either side of

    uvula in back of throat that produces

    antibodies

    Hard Palate: roof of mouth, hard ridges

    Soft Palate: further back in mouth endingin the uvula

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    Pharynx Common passageway for

    food, liquids, and air

    Pharynx muscles assist in

    swallowing of bolus

    Region connecting oralcavity & pharynx is the

    Oropharynx

    Epiglottis: flap of tissue

    that covers over openingof trachea (glottis)

    prevents food from

    entering airway

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    Swallowing

    Food

    Trachea moves up

    against epiglottis to

    close the opening

    & prevent food from

    entering the trachea

    Mucin is secretedby back of throat &

    esophagus wall

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    Structure of the Esophagus

    Muscular, flexible

    tube, ~25cm long

    3 layers:

    Mucosa (inner): lining

    covered in mucus

    Submucosa (middle):

    nerves, blood & lymph

    vesselsMuscularis (outer):

    circular & longitudinal

    muscle

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    Function of the Esophagus

    Cross-sectional

    View

    To conduct food from the pharynx to the stomach

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    Peristalsis

    A series of

    wave-like

    contractions

    that propelsfood along the

    digestive tract

    Q: What is it

    called when

    food moves

    upwards?

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    Structure of the Stomach

    J-shaped muscular sac, stretches with food

    3 layers of muscles: Longitudinal (outside), Circular

    (middle) & Oblique (inner folds)

    Inner lining is folded into accordion-like ridges called

    rugae inc SA

    Ridges contain gastric glands that produce gastric

    juice (enzymes, mucus, HCl) for chemical digestion

    Cardiac sphincter: ring of muscle controlling

    entrance into stomach

    Pyloric sphincter: ring of muscle controlling exit out

    of stomach

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    Stomach

    Q: How many litres

    of food can the

    stomach hold when

    fully expanded?

    Q: How long does

    it take your stomach

    to empty after ameal?

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    Bulk storage of undigested food

    Mechanical breakdown of food via

    rhythmic contractions (mixing of fluids)

    Chemical Digestion: breaks chemical

    bonds via hydrochloric acid (pH 2) and

    enzymes (pepsin & lipase)

    End product is chyme partially digestedfood in a semi-liquid state

    Functions of the stomach

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    Stomach Lining

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    Mixing & Rhythmic Contractions

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    Consist of a series of loops loosely attachedto the back of the abdomen

    Name is from small diameter (approx. 2.5 to

    3cm diameter, 7m in length) Mesentery: layer of connective tissue that

    holds small intestine together to prevententangling of intestine in abdominal cavity

    Ileocecal valve: ring of muscles (sphincter)that controls movement of material fromsmall intestine to large intestine

    Structure of the Small Intestine

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    3 Sub-regions of Small Intestine

    Duodenum

    Jejunum

    Ileum

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    Function of the Small Intestine

    Most of the chemicaldigestion ofmacromolecules &absorption ofnutrients occurs here

    90% of products areabsorbed in smallintestines

    Other 10% absorptionoccurs in stomach &large intestines

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    Structure of Intestinal Wall

    Lining has folded finger-like projections

    called villi increase SA

    Each villus has many microscopic foldscalled microvilli further increase SA

    to maximize absorption

    Network ofcapillaries & tiny lymph vessel

    called lacteal extend into hollow core ofeach villus

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    The Intestinal Wall

    *Note: only 2 layers of muscles (circular & longitudinal muscle)

    instead of 3 like the stomach (no oblique muscle)

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    Cross-section of Small Intestines

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    Surface of Intestinal Wall

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    Cross-section of Villus

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    Absorption within Small Intestines

    Nutrients are absorbed

    across Intestinal cells

    (Villus) either via the:

    Blood Capillaries amino acids &

    monosaccharides

    Lacteal glycerol &

    fatty acids

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    Functions within each Region

    Duodenum: (first 25cm, U-shaped)chemical digestion occurs here, chymemixes w/ digestive juices from pancreas,

    liver, gall bladder & intestinal wall Jejunum: (~3m long) most absorption of

    nutrients occur here, highly folded innerlining contains lots villi & intestinal glands

    Ileum: (~4m long) contains fewer & smallervilli, absorb nutrients & push undigestedmaterial into large intestine

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    Intestinal Movements

    Peristalsis: series of

    wave-like muscular

    contractions &

    relaxations Rhythmical

    Segmentation:

    mixing contractions

    that knead materialback and forth without

    propelling it forward at

    a very fast rate

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    Structure of the Large Intestine

    Large upside-down U-shaped organ

    Approx. 1.5m in length & 8cm in diameter

    Three main sections: ascending colon,transverse colon & descending colon

    Chyme enters caecum a small pouchconnected to ascending colon host to

    large # of bacteria that breakdowncellulose

    Appendix a finger-like projection at the tipof caecum function is still a mystery

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    3 sections of the Large Intestine

    Ascending

    Transverse

    Descending

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    Complete absorption of nutrients

    Reabsorb water, minerals & other useable

    materials prevents dehydration

    Absorb vitamins K & B (biotin, folic acid)

    produced by bacteria (E. coli)

    Form, compact & store fecal matter (waste &

    undigested material) prior to defecation

    *Note: movement of material via peristalsis

    Functions of the Large Intestine

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    Structure of the Large Intestines

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    Last portion of the digestive tract:

    Rectum: where feces are stored until

    eliminated

    Anal Canal: between rectum & anus

    passageway for feces, ends in Internal

    (involuntary) and External (voluntary) anal

    sphincters allows body to control timingof elimination

    Rectum & Anal Canal

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    Digestive Questions

    How long does it take to

    digest a meal?

    How is gas produced

    within along thedigestive tract (2 ways)?

    How does one get

    diarrhea & how does it

    happen?

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    Accessory Organs

    Pancreas, Liver &

    Gall Bladder

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    Accessory Organs

    Large organs outside the digestive tract

    that aids in chemical digestion

    Chemical secretions are carried by ducts

    that empties into the digestive tract

    3 Main Accessory Organs:

    Liver

    Gall Bladder

    Pancreas

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    Liver, Gall Bladder & Pancreas

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    Structure of the Liver

    Largest internal organ, brownish-red in colour,divided into 2 large lobes (L & R)

    Located just beneath the diaphragm

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    Function of the Liver

    Liver performs over 500 functions:

    Produces bile (greenish-yellow liquid) that

    contains bile salts from cholesterol that helps to

    emulsify large fat globules into smaller fatdroplets (easier fat digestion & lipase action)

    Emulsification: is a process that involves

    molecules attracted to water at one end and fats

    at the other end creating a suspension of smallfat dropletsstable emulsion

    Bile released via hepatic duct

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    Functions of the Liver

    Plays major role in metabolism (set ofchemical reactions that maintains life):

    Demolition: breaks down old RBC

    Recycler: parts of decomposed Hb arerecycled to make bile salts

    Storehouse: collects excess chemical inblood (i.e. fat soluble vitamins, glucose

    glycogen)Detoxification centre: detoxifies poisons

    ingested in food & water (i.e. alcohol)

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    Hollow, pear-shaped organ on the

    underside of the liver

    Not involved in enzyme production

    Storage warehouse for bile, release is

    triggered by hormone via cystic duct

    Gall Bladder

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    Gall Bladder

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    Structure of the Pancreas

    Leaf-shaped gland, ~20cm in length

    Located close to curve of stomach,

    attached to the duodenum

    Pancreatic juice enters duodenum via

    pancreatic duct

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    The Pancreas

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    Produces over28 digestive enzymes thatbreaks down lipids (lipase), carbohydrates(amylase) & proteins (trypsin, peptidase)

    Produces pancreatic juice, alkalinesubstance (NaHCO3) that neutralizesacidic chyme, so other enzymes canfunction

    Produces insulin (hormone that regulatesblood glucose levels), allows glucose toenter cells

    Pancreas

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    Pancreas & Diabetes Hypoglycemic: abnormally low-levels of

    glucose in blood (pancreas sends out too

    much insulin to break down sugar)

    Hyperglycemic: extremely high glucoselevels or diabetes (pancreas cant make

    enough insulin or body cant use insulin)

    Type 1: insulin dependent

    Type 2: non-insulin dependent

    Type 3: gestinational diabetes

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    AccessoryOrgans &

    their ducts

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    Summary of the Digestive System