Pedro Ruiz Gallo

Lambayeque, October 2012

NATIONAL UNIVERSITY

HUMAN MEDICINE SCHOOL

NATIONAL UNIVERSITY

HUMAN MEDICINE SCHOOL

Pedro Ruiz Gallo

TEAM:

STUDENTS:

Nº 03

TEACHER:

Dra. Rosa Gonzales

Llontop

Carlos Elera Gustavo

Adolfo

Farroñay Antón Iván

Guerrero Jaramillo

Sergio Daniel

Hinostroza Huamán

Adler

Llanos Tenorio Edgar

Jhasler

Quesquén Neciosup

Víctor

CURSE:Medical English

FIVE NEW GENES LINKED

ALZHEIMER´S

INTRODUCTION

Genes gateway understanding

Alzheimer’s

are a to

Researchers have grown the list of

known genes associated with the most

common form of the condition, which

affects memory and brain function the

elderly

How do these

discoveries

help patients?

Introduction

THE FINDING

There were five accepted late-onset genes

Now there are five

more

MS4A,

ABCA7,

CD33,

EPHA1 and

CD2AP

EVIDENCES

People with high

cholesterol are more

likely to get the

disease.

Evidences of five new genes linked Alzheimer’s

The discoveries double the

number of known genes to be

involved in Alzheimer's, to 10

from 5

Evidences of five new genes linked Alzheimer’s

In contrast, each of the new genes increases risk by no more than 10 to 15 percent.

Evidences of five new genes linked Alzheimer’s

CAUSES OF ALZHEIMER´S DISEASE

CAUSES

GENETIC FACTOR

lot of mutations in the

gene of amiloide's

precursive protein

FAMILY HISTORY

A variant of the

pathology that is

transmitted

genetically

VASCULAR DISEASE

The lifestyle factors and

conditions associated

with vascular disease

can increase the risk

AGE

mainly affect

60-65's elders

years

How do these discoveries help

patients?

With the discovery of these new

genes

which further confirms that

accelerated biological pathways

suspected Alzheimer's disease.

-Inflammation

-Cholesterol

-Cell transport

systems

The findings uncover brand new targets for

potential treatments for the disease,

whether they may be drugs, behavioral

changes or other therapies.