ICBZM 2015August 13-14, 2015 University of Washington, Seattle, USA

2nd International Conference on Bioinspired and Zwitterionic Materials

www.icbzm2015.com

SHORT PROGRAM

CONFERENCE INFORMATION AND SCHEDULE�

2nd International Conference for Bioinspired and Zwitterionic Materials August 13 — 14th, 2015

CHAIR: Shaoyi Jiang CO-CHAIR: Kazuhiko Ishihara CO-CHAIR: Jian JiLOCATION South Ballroom 211N Husky Union Building (HUB) University of Washington 4001 East Stevens Way NE, Seattle, WA

SPEAKERS AND POSTER PRESENTATIONS Invited talks: 15 minute talk plus 5 minutes for questions Short talks: 5 minute talk plus 3 minutes for questions Poster dimensions: 4’ x 3’ maximum

Thursday, August 13th7:15 AM Registration and light breakfast

8:00 — 8:10 AM Opening remarks

8:10 — 8:40 AM FEATURED TALK: Allan Hoffman with introduction by Buddy Ratner

8:20 — 10:00 AM INVITED TALKS SESSION 1 (CHAIR: Jian Ji) — Kazuhiko Ishihara, Xi Zhang, Matteo Santin & Lei Jiang

10:00 — 10:40 AM Coffee break, group photo, and poster set up

10:40 — 12:20 PM INVITED TALKS SESSION 2 (CHAIR: Kazuhiko Ishihara) Matt Tirrell, Ben Zhong Tang, Harm-Anton Klok, William Wagner & Tom Webster

12:20 — 1:30 PM Lunch (provided by the conference)

1:30 — 2:30 PM INVITED TALKS SESSION 3 (CHAIR: Joe Schlenoff) — Stuart Cooper, Keith Johnston & Yasuhiko Iwasaki

2:30 — 3:10 PM SHORT ORAL TALKS SESSION 1 (CHAIR: Joe Schlenoff) Jie Zheng, Dan Ratner, Gang Cheng, Andrew White & Mehmet Sarikaya

3:10 — 3:50 PM Coffee break and poster session

3:50 — 5:30 PM INVITED TALKS SESSION 4 (CHAIR: Dan Ratner) Curtis Frank, Jian Ji, Shengfu Chen, Joe Schlenoff & Shaoyi Jiang

6:00 PM Conference dinner at the University of Washington Club DINNER TALK: Buddy Ratner with introduction by Allan Hoffman

Friday, August 14th7:45 AM Light breakfast

8:20 — 9:20 AM INVITED TALKS SESSION 5 (CHAIR: Greg Tew) — Todd Emrick, Xuesi Chen & Julius Vancso

9:20 — 10:00 AM SHORT ORAL TALKS SESSION 2 (CHAIR: Greg Tew) Lingyun Liu, Cole DeForest, Weibor Tsai, Sarah Perry & Zhiqiang Cao

10:00 — 10:40 AM Coffee break and poster session

10:40 — 12:20 PM INVITED TALKS SESSION 6 (CHAIR: Cole DeForest) Linqui Shi, Tomohiro Konno, Yung Chang, Jan Genzer & Shin-ichi Yusa

12:20 — 1:30 PM Lunch (provided by the conference)

1:30 — 2:50 PM SHORT ORAL TALKS SESSION 3 (CHAIR: Zhan Chen) — Matt Bernards, Yapei Wang, Chun-Jen Huang, Yongsheng Leng, Lei Zhang, Jian Zhou, Kagya Amoako, Anjie Dong, Yong-Kuan Gong & Xiaoyan Yuan

2:50 — 3:30 PM Coffee break and poster session

3:30 — 5:10 PM INVITED TALKS SESSION 7 (CHAIR: Matt Bernards) — Zhan Chen, Tatsuro Goda, Greg Tew, Ji-Hun Seo & Tom Horbett

5:10 — 5:30 PM Student poster awards presented (Jian Ji) Announcement of 3rd ICBZM meeting (Kazuhiko Ishihara); Closing remarks

MAPS�

Overview map of campus vicinity

For walking directions between hotels and UW HUB, please visit the website, or scan the code the right.

MAPS�

University of Washington — central campus

ORAL PRESENTATIONS Thursday, August 13th Morning sessions �

— Coffee break — Group photo and poster set up

— Lunch —

INVITED TALKS SESSION 1 CHAIR: Jian Ji 8:40 — 10:00 AM

Photochemical Preparation of Phosphorylcholine Group Immobilized-Polymer Surface Kazuhiko Ishihara University of Tokyo

Supra-Amphiphiles from Molecular Architecture to Functional Assembly Xi Zhang Tsinghua University

Synthetic Extracellular Matrix Analogues for Cadaveric Pancreatic Beta-Cells Transplantation Matteo Santin University of Brighton

Bio-Inspired Interfacial Materials With Super-WettabilityLei Jiang

Institute of Chemistry Chinese Academy of Sciences

FEATURED TALK 8:10 — 8:40 AM INTRODUCED BY: Buddy Ratner

The Early History and Evolution of Non-Fouling, Protein-Repellant Surfaces

Allan Hoffman University of Washington

INVITED TALKS SESSION 2 CHAIR: Kazuhiko Ishihara 10:40 AM — 12:20 PM

Polyelectrolytes in Multivalent Ionic Media: New Physics and New Materials Matthew Tirrell University of Chicago

Biomedical Materials Based on AIE Luminogens Ben Zhong Tang Hong Kong Univ. of Science and Technology

Mechanochemistry of Surface-Grafted Polymers Harm-Anton Klok École Polytechnique Fédérale de Lausanne

Zwitterionic Materials for Reduced Thrombogenicity in Medical Devices William Wagner University of Pittsburgh

Biomedical Applications of Zwitterionic Materials Tom Webster Northeastern University

ORAL PRESENTATIONS Thursday, August 13th Afternoon sessions �

— Coffee break and poster session —

INVITED TALKS SESSION 3 CHAIR: Joseph Schlenoff 1:30 — 2:30 PM

Synthesis and Properties of Polyurethane Ionomers and Zwitterionomers Stuart Cooper Ohio State University

Zwitterions to Weaken Adsorption With Organic and Inorganic Surfaces Keith Johnston University of Texas

Photo Irradiation-Assisted Preparation of Biointeractive PC Surfaces Yasuhiko Iwasaki Kansai University

SHORT ORAL TALKS SESSION 1 CHAIR: Joseph Schlenoff 2:30 — 3:10 PM

Molecular Engineering of Functional Soft Materials at Biointerfaces Jie Zheng University of Akron

Employing Zwitterionic Chemistries to Enable Silicon Photonics for Clinical Applications Daniel Ratner University of Washington

Design and Development of Zwitterionic Conjugated Polyelectrolyte Platform as Next-Generation Biomaterials

Gang Cheng University of Akron

Methods for Combining Chemical Simulations and Experiments Andrew White University of Rochester

Molecular Biomimetics: Peptide-Enabled Surface & Interface Engineering in Technology and Medicine

Mehmet Sarikaya University of Washington

DINNER TALK 7:30 PM INTRODUCED BY: Allan Hoffman Reception at 6:00 PM in the UW Club

Converting Biomaterials Challenges to Opportunities: Optimism and Pessimism

Buddy Ratner University of Washington

INVITED TALKS SESSION 4 CHAIR: Daniel Ratner 3:50 — 5:30 PM

Self-Assembly of Cholesterol Tethered Within Hydrogel Networks Curtis Frank Stanford University

Bionanointerface: From Cell Membrane Mimic to Protein Mimic Jian Ji Zhejiang University

Zwitterionic Materials and Their Applications Shengfu Chen Zhejiang University

Zwitterion Interface from Polyelectrolyte Multilayers Joseph Schlenoff Florida State University

Molecular Understanding, Design, and Development of Ultra-Low Fouling Zwitterionic Functional Materials

Shaoyi Jiang University of Washington

ORAL PRESENTATIONS Friday, August 14th Morning sessions �

— Coffee break and poster session —

— Lunch —

INVITED TALKS SESSION 5 CHAIR: Gregory Tew 8:20 — 9:20 AM

New Synthetic Polymer Zwitterions as Interlays in Solar Cells Todd Emrick University of Massachusetts, Amherst

Nanogel-Incorporated Physical and Chemical Gels for Highly Effective Chemo-Protein Combination Therapy

Xuesi Chen Changchun Institute of Applied Chemistry

Chinese Academy of Sciences

Polymer Thin Films for Marine Biofouling Prevention: Effects of Surface Polarity and Charge

Julius Vansco University of Twente

SHORT ORAL TALKS SESSION 2 CHAIR: Gregory Tew 9:20 — 10:00 AM

Amino Acid-Based Zwitterionic Antifouling Polymers: Development, Biofouling Properties, and Applications

Lingyun Liu University of Akron

Photopatterning Hydrogel Biomaterials With Site-Specifically Modified Proteins Cole DeForest University of Washington

Conjugations of Anti-Fouling Materials on Functional CVD Poly-p-xylene Substrates Wei-Bor Tsai National Taiwan University

Effects of Polymer Architecture and Zwitterionic Moieties on Complex Coacervation

Sarah Perry University of Massachusetts, Amherst

Zwitterionic Materials and Translational Medicine Zhiqiang Cao Wayne State University

INVITED TALKS SESSION 6 CHAIR: Cole DeForest 10:40 AM — 12:20 PM

Regulation of Protein Folding by Artificial Chaperones Linqi Shi Nankai University

Cytocompatible and Reversible Phospholipid Polymer Hydrogels for Advanced Cell Engineering

Tomohiro Konno University of Tokyo

Zwitterionic Membranes: Design, Development, and Applications Yung Chang Chung Yuan Christian University

Swelling of Polyelectrolyte and Zwitterion Brushes by Humid Vapors Jan Genzer North Carolina State University

Polyion Complex Aggregates With Phosphobetaine Surfaces Shin-ichi Yusa University of Hyogo

ORAL PRESENTATIONS Friday, August 14th Afternoon sessions �

— Coffee break and poster session —

— Awards, announcement and closing remarks —

INVITED TALKS SESSION 7 CHAIR: Matt Bernards 3:30 — 5:10 PM

Molecular-Level Studies on Zwitterionic Polymer Surface Hydration in situ Zhan Chen University of Michigan

MPC as a Synthetic Ligand in C-Reactive Protein Biosensing Tatsuro Goda Tokyo Medical and Dental University

Zwitterions from Norborene-Based Monomers Gregory Tew University of Massachusetts, Amherst

Phosphorylcholine Group-Containing Surface Anchoring System: Useful Tool for Developing Cell Culture Devices

Ji-Hun Seo Korea University

Adsorption and Bioactivity of Adhesion Proteins Thomas Horbett University of Washington

SHORT ORAL TALKS SESSION 3 CHAIR: Zhan Chen 1:30 — 2:50 PM

Polyampholyte Polymers as a Versatile Biomaterial Platform Matt Bernards University of Missouri

An Ultra-Thermal-Sensitive Fluid for Flexible and Self-Healing Sensors Yapei Wang Renmin University of China

Novel Molecular Building Blocks for Anti-Biofouling Properties Chun-Jen Huang National Central University

Computational Modeling of Surface and Interfacial Phenomena: Membrane-Foulant Interaction, Metal-Organic Binding, and Nanoconfined Fluids

Yongshen Leng George Washington University

Biomedical Applications of Zwitterionic Particles Lei Zhang Tianjin University

Antimicrobial and Nonfouling Properties of Mixed-Charge Self-Assembled Monolayers: A Molecular Simulation Study

Jian Zhou South China University of Technology

Multimodal, Surface-Focused Anticoagulation Kagya Amoako University of New Haven

Integrin-Targeted Zwitterionic Polymeric Nanoparticles with pH and Reduction-Responsive Properties for Enhanced Drug Accumulation and Release in Tumor

Anjie Dong Tianjin University

Mussel-Inspired Substrate-Independent Surface Coating of Functionalized Polyzwitterions Yong-Kuan Gong Northwest University

Fluorosilicone Block Copolymers Xiaoyan Yuan Tianjin University

POSTER PRESENTATIONS Competition Posters Students and Postdocs �

No. Title Presenter

C1 A Facile Way Towards Multifunctional Membranes with Improved Antifouling and Anticoagulant Property

Tao Xiang Sichuan University

C2 Amino Acid-Based Zwitterionic Antifouling Polymers: Development, Biofouling Properties and Applications

Wenchen Li University of Akron

C3 Chain Flexibility in Self-Assembled Monolayers Affects Protein Adsorption and Chain Hydration

Wesley Beckner University of Washington

C4 Design and Construction of Peptide-Based Self-Assembling Nano-Beacons for Tumor Site Detection and Imaging

Xinpei Mao John Hopkins University

C5 Design of Zwitterionic Oligopeptide for Catch-And-Release of Target Cells Junko Enomoto Yokohama National University

C6 Engineering of Liver-Like Tissues Using Cell Adhesive Zwitterionic Oligopeptide Tatsuya Osaki University of Tsukuba

C7 Integrated Antimicrobial and Nonfouling Properties of Zwitterionic Polymers and Their Derivatives

Luo Mi Univ. of California, Los Angeles

C8 Mechanically Strong Agar/Pam Hybrid Double Network Hydrogels with Excellent Antifouling Properties

Hong Chen University of Akron

C9 Molecular Biomimetics: Peptide-Enabled Surface and Interface Engineering in Technology and Medicine

David Starkebaum University of Washington

C10 Molecular Design and Understanding of Zwitterionic Materials Qing Shao North Carolina State University

C11 Molecular Dynamics Simulations of Polyamide Membranes, Calcium Alginate Gel, and Their Interactions in Aqueous Solution

Yuan Xiang George Washington University

C12 Mussel-Inspired Polydopamine Coated 3D Polycaprolactone Scaffold Grafted with Bmp-2 for Bone Tissue Regeneration

Sang Jin Lee Korea Institute of Mach. & Mat.

C13 Nonfouling Polyampholyte Hydrogels as Drug Delivery Scaffolds Marcos Barcellona University of Missouri, Columbia

C14 Obtaining Thermodynamic and Structural Information of Surface-Bound Biomolecules from Biased Simulations

Kayla Sprenger University of Washington

C15 Photoreactive MPC Polymers for Effective Surface Modification of Versatile Biomedical Devices

Xiaojie Lin University of Tokyo

C16 Polyampholyte Copolymers with Well-Defined Charge Bias in Human Blood for Hemocompatibility

Chih-Chen Yeh Chung Yuan Christian University

C17 Preparation of Aqueous Two-Phase Systems Composed of Two pH-Response Polymers and Liquid-Liquid Extraction of Antibodies

Jialing Chen East China Univ. of Sci. and Tech.

C18 Quantification of the Fouling Resistance of Zwitterionic and Amphiphilic CVD Thin Films Utilizing Molecular Force Probe

Minghui Wang MIT

C19 Shell Sheddable Zwitterionic Nanoparticles Constructed from Bioreducible Raft-Rop Double Head Agent for Integrin-Targeted Drug Delivery

Pingsheng Huang Univ. of Massachusetts, Amherst

C20 Surface-Attached Orthogonal Gradient Networks for Medical Applications Pandiyarajan Cinnayan Kannan North Carolina State University

C21 Ultra-low Fouling Zwitterionic Hydrogels in Biomedical Applications Tao Bai University of Washington

C22 Ultra-Stable Nanoparticles Protected by Zwitterionic Polymers Yang Lu Wayne State University

C23 Understanding Charge Density in Polyelectrolyte Multilayers and Its Influence on Cell Adhesion

Carlos Arias Florida State University

C24 Zwitterionic polymer conjugation protects against antibody generation while maintaining enzymatic activity and prolonging circulation time

Susan Liu University of Washington

C25 Zwitterionic Surface Modification of Surface-Enhanced Raman Scattering Substrates for Sensitive and Accurate Detection in Protein Solutions

Fang Sun University of Washington

POSTER PRESENTATIONS Regular Posters

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No. Title Presenter

R1 A Facile Strategy to Create Zwitterionic Film on Silicon-Based Biosensor with Natural Amino Acid

Fang Chen Dailan University of Technology

R2 An Ultra-Thermal-Sensitive Fluid for Flexible and Self-Healing Sensors Yapei Wang Renmin University of China

R3 Antimicrobial and Nonfouling Property of Mixed Charged Self-Assembled Monolayer: a Molecular Simulation Study

Jian Zhou South China Univ. of Technology

R4 Biomedical Applications of Zwitterionic Particles Lei Zhang Tianjin University

R5 Biomimetic Design of Antithrombotic Peptides Lin Zhang Tianjin University

R6 Doxorubicin Conjugated Phospholipid Prodrugs as Smart Nanomedicine Platform for Cancer Therapy

Qiao Jin Zhejiang University

R7 Effects of Polymer Architecture and Zwitterionic Moieties on Complex Coacervation Sarah Perry University of Massachusetts, Amherst

R8 Effects of the Incorporation of a Zwitterionic Block into a Polycation on the DNA Condensation Properties: Microscopic Insight into Their Interaction Processes

Xia Han East China University of Science and

Technology

R9 Erasable Microporous Polyelectrolyte Multilayer Films as Delivery Platform for Hydrophobic Drugs

Kefeng Ren Zhejiang University

R10 Fluorosilicone Block Copolymers Tethering Quaternary Ammonium Salt Groups for Antimicrobial Purposes

Xiaoyan Yuan Tianjin University

R11 Integrin-Targeted Zwitterionic Polymeric Nanoparticles with pH and Reduction-Responsive Property for Enhanced Drug Accumulation and Release in Tumor

Anjie Dong Tianjin University

R12 Improving the Fouling-Resistance and Fouling-Release of Polyethersulfone Ultrafiltration Membranes Modified with Amphiphilic Random Copolymer Additive

Guangfa Zhang Zhejiang University

R13 Mussel-Inspired Substrate-Independent Surface Coating of Functionalized Polyzwitterions

Yong-Kuan Gong Northwest University

R14 Novel Molecular Building Blocks for Anti-Biofouling Properties Chun-Jen Huang National Central University

R15 Polyampholyte Polymers as a Versatile Biomaterial Platform Matthew Bernards University of Missouri, Columbia

R16 Protein And Bacteria Resistant of Novel Poly(Dimethylsiloxane) Based Polyurethane Elastomers Tethered with Zwitterionic Carboxybetaine

Qinghua Zhang Zhejiang University

R17 Supramolecular Interaction between Insulin and Cp1-11 Peptide and Their Assembly as Rapid-Acting Formulation

Yantao Chen Shenzhen University

R18 Tailoring the pH-Induced Aggregation Behaviors of Mixed-Charge Gold Nanoparticles for Photothermal Therapy

Huan Li Zhejiang University

R19 Zwitterionic Functional Materials: From a Fundamental Understanding to True Biocompatibility

Andrew Sinclair University of Washington

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PROGRAMS • Biomaterials • Interfacial Processes and

Thermodynamics • Biomedical Engineering

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