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2014 State of the Science Congress on Nursing ResearchSeptember 18-20, 2014

Amanda L Greene, PhD, MPH, RNSenior Program Officer, Research Integration & Evaluation

Opportunities for Nurse Researchers

About PCORI

An independent research institute authorized by Congress through the Patient Protection and Affordable Care Act.

Funds comparative clinical effectiveness research (CER) that engages patients and other stakeholders throughout the research process.

Seeks answers to real-world questions about what works best for patients based on their circumstances and concerns.

Our Strategic Goals

Influence Research Funded by Others

Speed the Implementation and Use of Evidence

Increase Quantity, Quality and Timeliness of Research Information

Our Funded Research

Studies the benefits and harms of interventions and strategies delivered in real-world settings

Compares at least two alternative approaches

Adheres to PCORI’s Methodology Standards

Is based on health outcomes that are meaningful to the patient population

Engages patients and other stakeholders at every stage

Is likely to improve current clinical practices

We Pay Particular Attention to…

Conditions that heavily burden patients, families and/or the health care system

Chronic or multiple chronic conditions

Rare and understudied conditions

Conditions for which outcomes vary across subpopulations

Our National Priorities for Research

Assessment of Prevention, Diagnosis, and Treatment Options

Improving Healthcare Systems

Communication & Dissemination

Research

Addressing Disparities

Accelerating PCOR and Methodological

Research

How Are Applications Reviewed?

Impact of the condition on the health of individuals/populations

Potential for the study to improve healthcare and outcomes

Technical merit

Patient-centeredness

Patient and stakeholder engagement

Applications are reviewed against five criteria:

Applications are reviewed by a panel of two scientists, one patient, and one other stakeholder.

PCORI’s Board of Governors makes funding decisions based on merit review and staff recommendations.

Research Must Engage Stakeholders at Every Step

Planning the studyConducting the studyDisseminating study resultsPCORI Engagement Principles

PCORIEngagement Rubric

A four-part rubric developed to help guide applicants, reviewers, awardees, and program officers on ways to engage patients andfamilies in conducting research

Formulating Research Questions

Patient-Centeredness

Data Integrity and Rigorous Analyses

Preventing/Handling Missing Data

Heterogeneity of Treatment Effects

We Work to Improve Research Methodology

In any study, methods matter. That’s why we’ve developed methodology standards that all research

should follow, at a minimum

Data Networks

Data Registries

Adaptive and Bayesian Trial Designs

Causal Inference

Studies of Diagnostic Tests

Systematic Reviews

Methodology Standards: 11 Broad Categories

Eugene Washington PCORI Engagement Awards

Provide “wrap-around” support and enhance impact of PCORI’s research initiativesThree award types: Knowledge, Training and Development, Dissemination and ImplementationAwards of up to $250,000

Objectives Engage new groups not

previously involved with PCORI Develop new mechanisms for

disseminating research findings Promote “research done

differently” by supporting engagement and partnering in conduct and use of CER

Evaluation

ENGAGEMENT

Additional Ways to Get Involved

Proposal Review; Design and Conduct of Research

Topic Selection and Research Prioritization

Dissemination and Implementation of Results

Find Us Online

www.pcori.org

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Amanda L Greene, PhD, MPH, RNSenior Program Officer, Research Integration & Evaluationagreene@pcori.org

Thank You