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John A.Moran Eye Center

65 Mario Capecchi Drive

Salt Lake City, UT 84132

801-581-2352

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FOCUS 2014 John A. Moran Eye Center University of Utah Health Care

Visionary

M o r a n a d v i s o r y c o u n c i l2

014

Wayne ImbrescIa John A. Moran Eye Center

claudIa s luttrell Salt Lake City, Utah

John a moran Palm Beach, Florida

randall J olson, md John A. Moran Eye Center

chase n Peterson, md Park City, Utah

lynn Ward John A. Moran Eye Center

steve Wynn Las Vegas, Nevada

norm a ZabrIskIe, md John A. Moran Eye Center

robert F bennett Falls Church, Virginia

John bloomberg La Jolla, California

reed brInton Salt Lake City, Utah

alan s crandall, md John A. Moran Eye Center

Ian cummIng Jackson Hole, Wyoming

steve deZII Las Vegas, Nevada

sPencer F eccles Salt Lake City, Utah

alan J hIrschFIeld Jackson, Wyoming

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2 Message from the Chair Visionaries Pushing Boundaries

4 Proctor Medal-Winning Visionary

8 Kayser International Award Winner

12 Passionate Ambassador of Pediatric Ophthalmology

14 A Remarkable Man Honored with a Remarkable Gift

16 Moran Around the World

18 Physician Spotlight

20 Hope in Sight

22 The Art of the Eye, The Eye as Art

24 Highlights

26 Awards

28 My Life Has Made Me an Expert on Blindness

29 Idiopathic Intracranial Hypertension: Relief in Sight

30 Judith Warner, MD, Shaping Future Ophthalmologists of the World

31 Cornea Fellowship: Valli Muthappan, MD

32 Residents and Fellows 2014-2015

34 Ophthalmologists 2014

39 Optometrists 2014

40 Research Team 2014

43 Community Clinics 2014

45 Donors 2013

51 Industry Leadership and Service 2013

54 Awards, Honors, and Appointments 2013-2014

56 Clinical Trials 2013

58 Technology Commercialization and Intellectual Property/Patents 2013-2014

60 Grand Rounds 2013

62 Published Research 2013

66 Research Grants and Contracts 2013-2014

72 National and International Presentations 2013

Official Publication of the John A. Moran Eye Center University of Utah Health Care, Salt Lake City, Utah 84132

John A. Moran Eye Center 65 Mario Capecchi Drive Salt Lake City, UT 84132 801-581-2352

EDITOR Steve Brown, Communications Manager

ExTERNAL RELATIONS TEAM/CONTRIBuTORS Linda Bult, Editor, Writer Tawnja Carballo, Development Specialist Deedra Lambert, Development Specialist Kirsten Mallik, Director of Development Shawn Nelson, Marketing Manager Esther Pomeroy, Communications Specialist Heidi Reid, Major Gifts Officer Lynn Ward, Executive Director, External Relations

OuTREACH DIVISION Joshua Cooper, Office Assistant Julie Crandall, Project Coordinator Tara Kisow, Program Coordinator Michael Yei, Manager

CONSuLTANTS Carolyn Hoffman, Writer Virginia Rainey, Editor, Writer Gordon Vetas, Intern

GRAPHIC DESIGN Spatafore Design

PHOTOGRAPHy Michael Schoenfeld, cover and major portrait photography

Jeff Allred Steve Brown James Gilman, CRA, FOPS Matthew Hepworth Carolyn Hoffman Bryan W. Jones, PhD Ace Kvale John McCarthy Timmy O’Neill Patrick Reddish

PRINTING Printers Inc. Salt Lake City, Utah

A special thanks to the many hard working Moran Eye Center employees, management, health care workers, physicians, patients, and researchers who generously contributed their time and talent to make this publication possible. Special thanks also to Kay Spatafore and Lori Garfield, designers.

For more information about the Moran Eye Center, visit us online at moraneyecenter.org. Follow us on Facebook at Moran Eye Center and on Twitter @MoranEyeCenter. Requests for additional copies of this publication may be sent to the following: Communications Manager, Moran Eye Center, 65 Mario Capecchi Drive, Salt Lake City, Utah 84132.

©2014 John A. Moran Eye Center. All rights reserved. The Moran Eye Center does not assume responsibility for any representation therein, nor the quality or deliverability of the product themselves. Reproductions of articles or photographs, in whole or in part, contained herein are prohibited without express written consent of the publisher, unless otherwise stated.

J O H N A . M O R A N E y E C E N T E R

ContentsFOCUS 2014

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“I am button-busting proud!” As Chairman of the John A. Moran Eye Center, I’ve always known that we employ some of the best people in the business. Over the years, it’s been rewarding and humbling to work alongside such a dedicated team of professionals and to share in their successes.

Lately, it seems the rest of the world is impressed by them, too. As you’ll see in the following pages, our work is being recognized nationally and internationally as our faculty are winning some of the most prestigious awards in ophthalmology. I am button-busting proud!

This has been a year of unprecedented honors for the Moran Eye Center. Wolfgang Baehr, PhD and Robert Marc, PhD—two visionaries who pushed the boundaries of what was thought possible in eye research—recently received two of the very highest awards in vision science, the Proctor Medal and the Paul Kayser International Award in Retina Research respectively.

Our leadership in eye research is being recognized in other ways as well. Gregory Hageman, PhD, Executive Director of the Moran Center for Translational Medicine, recently signed a collaborative agreement with Allergan, Inc. to help bring new therapies for age-related macular degeneration (AMD) to market. A partnership like this is unheard of in vision research and is a huge validation of the potential that Dr. Hageman’s work has in helping those with AMD.

This kind of recognition confirms that the Moran Eye Center is on the right track. It tells us that our peers worldwide recognize the contributions we are making to advance science and cure blindness. But we aren’t about to rest on our laurels—the incredible effort that has brought us to this level is only the beginning of our journey as we work to ensure that no person facing a blinding eye condition is without hope, understanding, or treatment.

Isaac Newton wisely said, “If I have seen further, it is by standing on the shoulders of giants.” In my 35-year tenure, the brilliance, heart, and commitment of the faculty and staff at Moran have propelled me to transform a one-person division of ophthalmology into an internationally recognized center of research, education, outreach, and patient care. I am proud to dedicate this issue of FOCUS to our faculty and staff and to thank them for all that they have achieved.

Sincerely,

Randall J Olson, MD Professor and Chair, Department of Ophthalmology and Visual Sciences; CEO, John A. Moran Eye Center, University of Utah

message from the chair

Visionaries Pushing Boundaries

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“Until we understand a process, we don’t even know what it is we don’t know. We don’t know what is really broken until we know what works. Wolfgang is one of the top researchers getting at those core processes,” notes Moran CEO Dr. Randall J Olson. “I was so pleased to hear that he was given this honor, and in my mind, it was about time!”

Among his many discoveries, Baehr is known for identifying the second and third components of the phototransduction “signaling” cascade: transducin, cGMP phospho-diesterase and guanylate cyclase-activating proteins. His was the first breakthrough since the light-sensing pigment, rhodopsin, was identified 100 years earlier. “We were convinced that the signal the photoreceptors used was the ion calcium, and there were meetings on it—international meetings—and we were all wrong! Wolfgang’s work was a big piece of the core body of knowledge that is our current understanding of photoreceptor function,” says Robert E. Marc, PhD, Director of Research at the Moran Eye Center.

In 1992, Baehr generated the first transgenic mouse model based on the first rhodopsin mutation linked to dominant retinitis pigmentosa (RP). When research uncovers a disease-causing mutation, the next step is up to Baehr as he and his team think of ways to delay or cure the disease. He genetically engineers mice to simulate the human retina disease in order to study the disease’s progression. “A ‘knockout’ gene prevents the gene from expressing its protein, so you destroy the gene by deleting an essential part of it,” he explains. “This helps one to understand the function of the normal gene product.”

“Loss of sight is a devastating problem for so many people. if we can

come up with an understanding of how an eye disease develops and

then discover methods to either ameliorate the progress of that disease

or finally to cure it, that would be my mission,” says renowned biochemist

Dr. Wolfgang B. Baehr, PhD, recipient of the prestigious 2014 Proctor

Medal. the Proctor, given by the Association for Research in Vision and

ophthalmology, is an international award recognizing contributions to vision

research in the basic or clinical sciences as applied to ophthalmology.

the Proctor Medal honors Baehr for a lifetime of achievement for his many

significant scientific discoveries regarding retina disease.

Proctor Medal-Winning Visionary, Wolfgang Baehr

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A Call from Robert MarcBorn in born Mannheim, Germany, Baehr studied organic chemistry at the University of Heidelberg. His retinal research career was launched in the Department of Biochemistry, Princeton University, in 1976. At the Cullen Eye Institute at Baylor College of Medicine, he was a Jules and Doris Stein Research to Prevent Blindness Professor from 1987-1994. While at Cullen, Baehr got a call from Robert Marc who said, “Wolfgang, I have a job for you—will you come?”

Baehr joined the Moran Eye Center in 1995. He is the Ralph and Mary Tuck Professor of Ophthalmology and Visual Sciences with adjunct appointments in the Department of Neurobiology and Anatomy and the Department of Biology.

Today, Baehr heads the Moran Eye Center’s lead team in discovering the mechanisms underlying incurable retinal diseases using techniques from molecular biology, biochemistry, and neurobiology. His lab is exploring the role of protein trafficking and ciliogenesis in photoreceptor function—how cargo (protein) is assembled, targeted, and transported through cilia to the destination where it performs its function. Cilia are critical in sensing developmental signals of cells. Nonfunctioning cilia cause genetic diseases, such as RP, in which the rods of the peripheral retina degenerate and may progress to blindness. Baehr is also the recipient of a 2013 ALCON Award and a 2014 Nelson Trust Award for Retinitis Pigmentosa from Research to Prevent Blindness, Inc.

Scientist with a Nurturing NatureThis soft-spoken biochemist with traces of a lyrical German accent is a dedicated researcher-professor-mentor who is also a father, gardener, biker, and mountain man. Inspired by biological systems everywhere, he often trucks his family to the nearby Uintah Mountains to picnic and chop fallen wood, “to get them away from the computer,” he says. And at his hillside home, he has tirelessly chiseled away rock and brush to create a terraced mountain garden retreat with grapevines, daffodils, iris, allium, and sage.

Cecilia Gerstner and Dr. Wolfgang B. Baehr, Baehr Lab

“When you do an experiment, you never know the outcome— that’s always the fascination.” —Wolfgang Baehr, PhD

Dr. Baehr with sons Hans and Steph

Jeanne M. Frederick, PhD, retinal cell and molecular biologist, is married to Dr. Baehr, and the two often collaborate

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RobeRt MARC oN WolfgANg bAehR:

“Wolfgang is simply the finest, purest scientist I know. If you

map out his scientific history, you’ll discover that he has been

at the fore of every major movement in biological science, from

DNA sequencing, to protein assemblies, to gene therapies and

supramolecular trafficking. I find the scope breathtaking and

the depth, technical prowess, and insight simply amazing. He is

also one of the finest mentors I’ve been privileged to know.”

Photo: Bryan W. Jones, PhD—The intricate structure of blood vessels that supply a healthy retina

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Marc’s life work is mapping the infinitely complex circuitry of the retina, a monu-mental task he says is “a challenge that spans many lifetimes and many individuals, so I’ve been privileged to make some headway—with the help of a lot of mentors. The Kayser Award is a very big deal for me. So many people who I admire tremendously have won in the past, and to be put on the same list with them is pretty challenging. It also means that the body of work I’ve done impacts our understanding of vision in ways I didn’t antici-pate it would.”

Marc joined the Moran Eye Center in 1993, arriving by way of the University of Texas Houston where he held an endowed chair and was widely known for his discoveries in color vision. The first of his many notable achievements was mapping the color receptors of the retina. Together with his graduate mentor, Harry Sperling, he produced the first complete color maps of retinal cone arrays. Postdoctoral work with William Stell at UCLA launched a career-long interest in tracing neural pathways with molecular markers and electron microscopy, providing the first frameworks for neurochemically defined feedback systems in the retina.

Visualizing ChangeA decade ago, the Marc Lab at Moran demonstrated that diseases such as age-related macular degeneration and retinitis pigmentosa began by rewiring the neural circuits in the eye, but no one had a complete idea what that circuitry looked like or how it worked. To begin to understand those diseases, he and his team needed to create what was then a “dream” of a photo map, called a connectome. It would be the first complete interactive digital image of the network of nerves and neurons that make up the retina—a map so dense it could zoom down to the level of an individual synapse and track exactly how it sparked with the others—and then zoom out to larger patterns made by thousands of synapses together.

renaissance man: geeking out and digging in

Robert E. Marc, PhD, Director of Research, John A. Moran Eye Center, is a

Distinguished Professor of ophthalmology and holds the Calvin and JeNeal

hatch Presidential Chair in ophthalmology at the University of Utah. he has

been named by the international society of Eye Research as the recipient of

the houston, texas-based Retina Research foundation’s 2014 Paul Kayser

international Award in Retina Research. this award recognizes lifetime

achievement by a vision scientist who has made a significant contribution to

the understanding of vitreoretinal diseases or disorders.

Kayser International Award Winner Robert Marc

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But, given the technology available at the time, it was basically impossible. A single 3D connectome map can require more storage space than 100 desktop computers. Marc and his team began assembling the images anyway, with Marc insisting “technology will catch up with us.” Moran donor Martha Ann Healy believed in them and bought a top-of-the-line electron microscope, which they repurposed for high-speed imaging, collaborating, all the while, with the University of Utah’s Scientific Computing and Imaging Institute to write entirely new code to manage the data. A few years later, “technology caught up.” In 2011, the Marc lab unveiled a retinal map of unprecedented completeness and resolution. Today, they are the lead team in discovering the nature and scope of retinal remodeling and in searching for mechanisms to control it. “Why should we focus on biological details when the need for cures is so pressing?” Marc asks. “Because the answers are in those details.”

Apples & AlgorithmsWiry, silver-haired, with a deep boom of a voice, the El Paso native sometimes sports a ponytail and well-worn jeans with a Texas-sized belt buckle. More than one colleague has described him as a “renaissance” man. One of his passions is the heirloom apple orchard he and his wife, Ann Torrance, have planted in the tiny town of Torrey, in Central Utah. “Science is child’s play compared to farming,” he says. “Computers don’t lift shovels. But I am happiest outdoors.” However, once a scientist, always a scientist: “The genetics, physiology, and chemistry of apples and plant biology and animal husbandry all overlap with my interests in mapping metabolic networks. Indeed, I think many of the tools we’ve developed for studying retinal metabolism and mapping retinal degenerations have powerful applications in agronomy. To my eyes, it’s all the same problem: interacting networks of cells carrying out genetic programs in changing environments. I could talk for hours on the organization of the retina or the evolution of apples.”

“Why should we focus on biological details when the need for cures is so pressing?” Marc asks. “Because the answers are in those details.”

Robert Marc at the JEOL JEM-1400 Electron Microscope

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“Robert works harder than most.

Part of that is because of his passion

for understanding how the retina

is wired. He geeks out on it, digs

in, and gets really excited when we

discover something new. And with

the connectomics project, we discover

something new almost daily.”

—Bryan W. Jones, PhD, Marc Lab Researcher

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epic travelsAs Moran’s ambassador of pediatric ophthalmology, Hoffman has traveled the globe for over 14 years—often to remote areas—healing the eyes of the children of the world. He has played a pivotal role in training international doctors in pediatric surgery, including preventative and post-surgery eye care; in establishing pediatric eye-care protocol where there previously was none; and in bringing international doctors to Moran to train, spearheading our International Observer Program. As Chief of the Division of Pediatric Ophthalmology and Eye Muscle Disorders, Hoffman specializes in retinopathy of prematurity, ocular genetics, craniofacial disorders, pediatric cataracts, and complicated strabismus.

Each year, he leaves his practice at Primary Children’s Hospital and the Moran Eye Center in Salt Lake City, Utah, to travel to Bhutan, Nepal, Ghana, Trinidad, India, or Indonesia to spend a week or two to train physicians. He makes his own travel arrangements, packs his own instruments and supplies, and is often accompanied by his wife, Carolyn—“the warm-fuzzy side of the operation,” he says. On one epic trip he traveled in a pickup truck for two days, 12 hours each day, to a blind school for children in Bhutan. As the only provider of such surgery during his annual visits, Hoffman demonstrates his preferred way of taking care of patients. In turn, physicians whom he has trained travel to Salt Lake to observe his practice in Utah. Here at home, Hoffman has conducted eye surgery screenings in Monument Valley on the Navajo Nation.

healing Children“There are several challenges treating children,” says Hoffman. “Those issues are the same worldwide, but our ability to deal with them is particularly limited in developing countries. Most pediatric problems are due to structural abnormalities and require surgical interventions, but the same surgical procedures commonly performed on adults do not work well on children. Often, the issue of even putting kids safely to sleep for surgery and then getting them back safely to their parents is a big issue. For the best outcome, kids need an extensive period of rehabilitation. It is essential. THAT’S the problem in a nutshell.”

“It was in 2000 that I asked Bob to help on one of our missions. To my surprise, he

did not have a passport and had not been out of North America except for Canada

and Mexico. After minimal cajoling, he obtained a passport and came to Kumasi,

Ghana. Since that first trip, he has become one of the most ardent proponents of the

International Division, teaching dozens of surgeons in Africa, Bhutan, and Asia on

surgical management of pediatric eyes. He has welcomed them here on fellowship

and then returned to their homes to further the cause.

He is passionate about teaching, demanding precision and a thoughtful approach but

always with the patient’s best interest at heart. He continues to help expand pediatric

ophthalmology world-wide, working with the American Academy of Ophthalmology,

ORBIS, and of course, the Moran Eye Center. He is a great ambassador!”

—Alan S. Crandall, MD

Passionate Ambassador of Pediatric Ophthalmology, Robert Hoffman, MD

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A Juggling ActAnother part of the challenge in treating children is trying to increase physician numbers and push education. “When you have a referral population of potentially over 20 million people, it’s a juggling act trying to meet the manpower needs for the sheer numbers of patients,” says Hoffman. It is an issue of getting the word out to other physicians, getting information back to physicians, getting to see patients early, and getting enough operating time to be able to take care of all those kids. It is changing, slowly, by word of mouth. You need 10 or 15 more people doing what one person is doing now—from a public health standpoint, there are issues to be addressed there.”

his DreamWhile at the Komfo Anokye Teaching Hospital in Kumasi, Ghana, with Crandall, Hoffman trains doctors to do pediatric glaucoma surgery. “We see everything: kids with eye injuries; kids with head trauma; kids who had glaucoma surgery; kids who need glasses, patching, and surgery. We arrange vision support services for infants, for preschoolers, or school-age children to make sure kids get the information and education and best attention that they deserve. Early on, it became clear that we needed to have someone with additional skill and expertise,” he notes. “A wonderful Ghanaian ophthalmologist, Dr. Peter Osei-Bonsu, who studied in the USSR and trained in the UK, was the first person I brought to Moran to train. And that training has limitations because he couldn’t operate here—he came as an observer for three months, following me around the clinic and operating room, examining preemies in the NICU. Then we did hands-on training with his patients when I went back to Ghana each year. So that has evolved. We have worked together, and I’ve been there yearly ever since. Work hard, play hard, give back. If you give back, you can make a difference—what you do will matter.”

Drummer: Robert Hoffman | Keyboardist: Jeff Schunk | Guitarist: Bob Bolte Vocals: Susan Etheridge | Bass: Jon Van Allen | Lead Guitar: Bill CuttingLead Guitar and Mandolin: Steve Santora | Dobro and Banjo: Joe Sherboti, guest performer

“Alan has been a phenomenal inspiration to me. He has a tireless approach to operating— sometimes until 8:00 to 10:00 at night. Nothing ever bothers him. He will deal with every set up and situation—he just deals with it.” —Robert Hoffman, MD, commenting on Alan Crandall, MD

the Wilson ProjectAs drummer for The Wilson Project, Hoffman plays regularly for benefits around Salt Lake with other minstrel-doctors. On his international trips, he takes a travel drum called a djimbe that he got in Ghana one year and has been known to engage in impromptu street performances entertaining locals.

Dr. Robert Hoffman and Carolyn Hoffman

Dr. Robert Hoffman with pediatric patient in Ghana

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Dr. Geoff Tabin Awarded the

John E. and Marva M. Warnock

Presidential Endowed Chair

in OphthalmologyFor most people, a bucket list like this would be plenty:

Earn a BA from Yale Earn a Marshall Scholarship

MA from Oxford Graduate with an MD from Harvard;

complete an ophthalmology residency at Brown and a cornea fellowship in Melbourne, Australia

Invent bungee jumping Become the fourth person in the

world to scale the Seven Summits, the highest points on each of the seven continents

Become a world-renowned ophthalmic surgeon

Write and publish one highly acclaimed book and inspire a second one

Personally perform surgeries that restore sight to thousands of blind individuals in emerging countries

Strike a pose on the cover of National Geographic Adventure magazine

Become a tenured professor at a major university

Meet the 14th Dalai Lama and receive his highest award

Dr. Geoff Tabin has checked them all off, but he is still working on his most important lifetime goal:

Eradicate preventable and curable blindness through high-quality ophthalmic care, education, and the establishment of a world-class, worldwide eye care infrastructure.

A Remarkable Man Honored with a Remarkable Gift

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life’s Calling It was in his third year at Harvard Medical School when he discovered a passion for ophthalmology—on a climb of Mt. Everest. While watching a Dutch medical team perform cataract surgery on a needlessly blind Himalayan woman, he knew he’d found his life’s calling. After completing his ophthalmology residency and cornea fellowship, Tabin went to Nepal to work with visionary ophthalmic surgeon, Dr. Sanduk Ruit. Adopting Ruit’s innovative methods of delivering high-quality cataract surgery at a very low cost, they founded the Himalayan Cataract Project and committed to eliminating preventable blindness in the region. As co-director of Moran’s International Outreach Division, Tabin says, “We perfected a six-to-seven-minute, low cost sutureless cataract operation two decades ago. Now, our vision is to work with ophthalmologists around the world to create sustainable systems that reach the most unreachable patients through teaching ophthalmic care, training local doctors in cataract surgery, educating local health care providers, and establishing self-sustaining eye care centers where they have not existed.”

Sustainable givingDr. Tabin and the Moran Eye Center are receiving a remarkable boost to our outreach program from a couple with their own record of extraordinary contributions to society. John E. and Marva M. Warnock have been longtime supporters of Dr. Tabin and Moran’s outreach work. They have now provided a generous presidential endowed chair that will further this great work of restoring sight and saving lives in perpetuity.

As proud University of Utah alumni, the Warnocks have built a powerful legacy of philanthropy on campus. The flagship building of the College of Engineering bears their name, and they have endowed chairs for instructors in mathematics and computer science, for visiting artists in the College of Fine Arts—and now for the Moran Eye Center. “Marva and I are proud to support Geoff,” says John Warnock. “His work saves thousands of people each year from blindness and death. This gift was one of the easiest decisions we’ve ever made.”

In 1982, John Warnock altered the history of computers, the art and design world, and more, as co-founder of Adobe Systems, Inc. He currently co-chairs its board. Marva Warnock is an artist and designer as well. She currently serves on the University of Utah’s National Advisory Council and on the advisory boards of the Utah Museum of Fine Arts and the Springville Art Museum.

Of the 39 million blind individuals worldwide, almost half suffer from treatable cataracts.

Dr. Geoff Tabin on Cholatse in Nepal

Dr. Geoff Tabin receives the “Unsung Heroes of Compassion” Award from his Holiness the Dalai Lama in 2009

Left to right, Dr. Geoff Tabin, Dr. Randall J Olson, Marva M. Warnock, John E Warnock

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Alan S Crandall, MD To “see” the happiness in a patient whose vision is restored brings joy to us, but it also allows that person to no longer be a burden to family and society. It returns dignity and purpose to his or her life.

Moran Around the World

every year, funded solely by donations, the

outreach Division of the John A. Moran eye

Center provides eye care and conducts

medical missions in over 40 countries around

the world and throughout the state of Utah.

Whether working at outreach medical eye

camps, local hospitals, or community clinics,

the Moran team focuses on teaching local

physicians to perform surgeries and on

training local clinicians and staff to perform

basic ophthalmic procedures.

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Robert O Hoffman, MD Training pediatric ophthalmologists in developing countries allows me to make a difference on an ongoing basis, helping to decrease the burden of childhood blindness. It has also allowed me to travel with family and friends, see new places, experience new cultures, and make new friends around the world!

Geoffrey Tabin, MD There’s no miracle in medicine like restoring sight to a person with cataracts. Even after 20 years, I still tingle when we go to remove the eye patches.

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Balamurali K Ambati, MD, PhD, MBA Manava Seva Madhava Seva, in Sanskrit, means “Service to man is service to God.” The gift of sight is the most precious of our senses, and offering our time, hearts, and hands to those in need around the world allows us the opportunity and privilege to make a difference by shining light into areas and lives which had been darkened by blindness. Piercing the veil indeed offers a window into the soul. It is my honor to work with Moran’s unique ensemble of physicians and staff who reach out and touch people suffering from blindness around the globe.

Paul S Bernstein, MD, PhD Retina poses a particular problem for international ophthalmology because it requires expensive equipment and supplies, and acquiring the required technical skills can be a challenge for the local aspiring retina specialist. I enjoy such challenges, and it has been particularly gratifying to participate in the establishment of fully functioning retina services in Nepal and Bhutan. And I hope to see similar successes in Africa in the near future.

Craig J Chaya, MD Everything that I have is a gift from God. Serving others is the best way I can say thanks and honor Him with my life.

Roger Furlong, MD It’s amazing to see what happens when somebody has their sight restored. Working and traveling with people so focused on helping others is very inspiring. There’s no better way to experience a different culture than to be immersed in it.

David Dries, MD I do outreach work because I’m healthy and capable of helping. I respect the dignity of those less lucky than I am and want to set an example for my sons.

Donnell J Creel, PhD I find participating in the International Outreach Program the most rewarding part of working. The people are always appreciative and their feedback reflects that we are making a positive difference.

Physician Spotlight

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Bradley J Katz, MD, PhD What I enjoy most about teaching internationally is singularity of focus: I’m there for one reason and one reason only. I can focus completely on teaching as much as possible during the time I’m allotted. There is no agenda and no paperwork—just me and other doctors who are eager to learn.

Julia Kleinschmidt, PhD, LCSW Life has been so good to me, and I have been given much. Out-reach work is my way of giving back. This passage from Anne Lamott’s book, Help Thanks Wow: Three Essential Prayers, expresses it well: “Gratitude begins in our hearts and then dove-tails into behavior. It almost always makes you willing to be of service, which is where the joy resides…When you are aware of all that has been given to you, in your lifetime and in the past few days, it is hard not to be humbled, and pleased to give back.”

Jeff Pettey, MD I do outreach work because together we can return a person to participating in life.

Colleen Schubach, OD The Moran Eye Center Outreach Program allowed me to touch the lives of others with eye care—something that we often take for granted. These people’s lives were compro-mised and made more difficult due to eye problems. After the eye care they received, I witnessed their joy, discovery, and new beginnings.

Albert T Vitale, MD We do outreach work as our charge in being on the planet is to help one another daily. As Dr. Martin Luther King, Jr. said, “Life’s most persistent and urgent question is, ‘What are you doing for others?’ ”

Mark D Mifflin, MD I do outreach work because I CAN. I think being a physician is a great privilege and along with that priv-ilege comes an inherent desire, and even an obligation, to serve people who are less fortunate and in need. As an eye physician and surgeon, I realize that I am only a very small part of a bigger team of charitable and loving individuals who make this work happen—and I would like to express my gratitude to all those who give their time, talents, and financial support.

Here, in their own words, are the many reasons Moran doctors choose to offer their exceptional services to help those in need.

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Moran Launches New Fundraising Campaign

With the help of our campaign co-chairs, each a pillar of Utah’s business and philanthropic community, the Moran Eye Center has launched our first fundraising campaign in nearly 10 years.

Hope in SightLeft to right: Thomas D. Dee III, A. Scott Anderson, John H. Firmage, III

Meet Our Campaign ChairsThese outstanding community leaders join us in our dedication to meeting ongoing challenges—from finding new treatments for macular degeneration to eradicating preventable blindness. Indeed, their leadership has already inspired over $18 million in gifts.

Honorary Chairs Our honorary chairs have played major roles in building and supporting the Moran Eye Center over the years: bill and Pat Child, lisa eccles, and Sharon Steele-Mcgee

thomas D. Dee III

Lawrence T. Dee and Janet T. Dee Foundation “The research needs to continue. And one day, there will be a cure for AMD.”

A. Scott Anderson

President and CEO of Zions Bank “I think of looking at my new granddaughter, seeing her smile, seeing her squeeze my finger, and I think, what would it be like if I couldn’t see?”

John h. firmage III

President, Firmco Financial Inc., BMW of Murray “I want to be involved with things that don’t take thirty years. And Moran seems to have figured that out.”

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Because more than six million Americans are blind from diseases

like age-related macular degeneration (AMD)—which we still can’t

cure—with millions more losing vision each day. At the same

time, our researchers are astonishingly close to developing new

therapies for treatments, and we do not want to slow them down.

Because hope is in sight.

three Priorities of the $22 Million hope in Sight Campaign:

Research: Hope begins with Moran’s extraordinary research. Some of our most important breakthroughs have come from unexpected corners, and broad support allows our scientists to be bold, collaborative, and creative.

Center for translational Medicine: The CTM’s public-private partnership model is leading to new therapies in a fraction of the usual time and cost—but the costs are still high. Donor support keeps our team focused on bringing those new treatments to clinical trials.

outreach: Even as we pursue new cures, many still need the ones we already have. Our outreach program brings sustainable eye care to underserved communities from rural Utah to Sub-Saharan Africa, restoring sight and training local physicians to provide care long after we leave.

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Why Now?

Research holds the KeyIn just 34 years, the John A. Moran Eye Center has become a global leader in ophthalmic research, care, and education. Dr. Randall J Olson has spent decades building a scientific team that has made major advances in the fight against AMD and other blinding eye diseases. The science is so promising that in 2013, Allergan, Inc., a major pharmaceutical company, signed an exclusive research and development agreement with Moran’s Center for Translational Medicine (CTM) to fast-track key discoveries into new medicines and clinical trials. And now, we are on the threshold of something revolutionary.

But while we are making significant strides, research faces its toughest funding environment to date. As other organizations are scaling back, here at the Moran, we are unwilling to “put hope on hold.” Continued, gracious philanthropic support enables our scientific team to stay intently focused on new hope, understanding, and treatment.

We must never give up hope that we can accomplish things that were previously considered impossible.”

—John A. Moran

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Every year, ophthalmic imaging technology becomes more and more sophisticated. As images of the eye—all

the way down to the level of microns—help doctors and researchers in their discoveries, diagnoses, and

treatments, they can also reveal patterns as exquisite as any fine lace or work of abstract art. Here are some

favorite images from Moran researchers and from our Ophthalmic Imaging and Videography Department.

The Eye as Art

“Victorian Lace” In one of her favorite photos, ophthalmic imager Paula Morris shows corneal epithelial cell ingrowth following a LASIK procedure with the contrast heightened to make the cell growth more striking.

“Diaphanous Dance—A New Art Form” “As ophthalmic photog-raphers, we are called upon to record fluorescence as a dye flows through the retinal circulation. We take pictures using a blue flash at timed intervals to catch predicted phases while the circulation carries it on a wild ride of several laps through the body. Regulated by the pulse of the heart, we photograph it going through the smallest channels in the retinal capillaries. But what if we set the dye free to flow in an unpredictable path? As it turns out, the dye disseminates in water in a diaphanous dance of swirling fluorescent color.” —Jim Gilman, Project Administrator of Ophthalmic Imaging, Moran Eye Center.

The Art of the Eye

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“Lunar Landscape” This pupillary membrane by James Gilman appears almost like a lunar landscape. It was the second place winner of the slit lamp category at the Ophthalmic Photographer's Society 2013 Scientific Exhibit and was featured on the April 2014 cover of Ophthalmology Magazine. Using a technique called “focus stacking,” Gilman merged two images—focusing one on the elevated areas of the iris and focusing the other on the lower areas of the iris.

“Ectopia Lentis” Moran ophthalmic imager Glen Jenkins shows the partial displacement of the crystalline lens. To Jenkins it “looks like a picture of a planet through a spaceship portal.”

“Confetti and Streamers” A region of retina from a goldfish is analyzed using tools called computational molecular phenotyping that reveal the metabolic state of all the cell types in tissues. Captured by National Institutes of Health-funded researchers, Robert E. Marc, PhD, and Bryan W. Jones, PhD, this image was a first place winner in the BioArt 2013 competition. Dr. Francis Collins, NIH Director, featured it on his blog, writing that “it looks like a celebration with confetti and streamers…but what such images reveal may be far more than a pretty picture…this map of neurons provides a baseline for understanding, and perhaps ultimately treating, diseases of the retina that alter the circuitry.”

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m o r a n e y e c e n t e r H I G H L I G H T S 2 0 1 4

Roger P. Harrie, MD, is a clinical professor of ophthal-mology and practices comprehensive ophthalmology with a special interest in ocular ultrasound—a technique used to diagnose and follow the progression of disor-ders affecting vision, similar to how electrocardiograms (ECGs) are used to monitor heart disease. The second edition of his text, Clinical Ophthalmic Echography (2014 Springer), offers a unique case-study approach that includes 308 studies and more than 370 ultrasound im-ages. He coauthored the book with Cynthia J. Kendall, RDMS.

CliniCal OphthalmiC EChOgraphy

Diagnostic Ophthalmology (2014 Amirsys, Inc), by Balamurali K. Ambati, MD, PhD, MBA, and Brian C.Stagg, MD, is a comprehensive reference textbook that provides vital information about the 280-plus most common diagnoses encountered in an ophthalmologic practice. One of the book’s key features is that it provides high-quality color images for every diagnosis. Moran’s Ophthalmic Imaging Project Administrator, James P. Gilman, CRA, FOPS, was the book’s image editor.

DiagnOstiC OphthalmOlOgy

Vitreoretinal surgeon Mary Elizabeth Hartnett, MD, has published the second edition of her textbook, Pediatric Retina (2014 Wolters Kluwer Lippincott Williams & Wilkins), the main industry reference on pediatric retina. “The text brings together collected knowledge from colleagues worldwide, which I believe pushes all of us to be challenged in our thinking and to find truths regarding science and medical treatment,” noted Hartnett. “The textbook really incorporates basic science and clinical understanding.”

pEDiatriC rEtina

Three Definitive Texts

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the ProblemFour bioengineering students intrigued with Dr. Olson’s patent for an anti-infective intraocular needle won the 2014 grand prize. Harjit Kaur, Annicka Carter, Jeremy Hammer, and Nick Rejali developed a product that can potentially solve the problem of introducing infection when injecting needles into the eye. “When a drug is injected into the eye, bacteria from the eye lodges inside the hollow part of the needle, where it can cause infection,” says Hammer. “The general idea is that you need a film to protect the needle,” says Olson. “They came up with poly-lactic-co-glycolic-acid (PLGA). I said, ‘Wow, if it will work and adhere, that would be great.’ They really did some innovative stuff.”

Each year, more than 200 University of Utah bioengineering, medical, and business students team up with physician-mentors to transform science and medicine in the U’s Bench-to-Bedside competition. The goal is to find creative solutions to clinical medical problems.

Mentorees Win Bench-to-Bedside Grand Prize

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the SolutionThe “innovative stuff” is to dip-coat biodegradable PLGA onto the needle tip, creating a membrane that blocks bacteria from contaminating the needle bore. Then, a stainless steel rod is pushed through the needle, which punctures the membrane after the needle is already inserted, delivering a bacteria-free drug. This process occurs by way of a hub that is attached to the tip of the syringe. The hub provides one port for puncturing and removing the rod and another port for the standard needle. The group used 3D printers to create solid prototypes of the hub.

Students were required to work with a mentor to evaluate the technical and functional issues of the problem. They created a project plan, identified user needs and marketing requirements, and created design specifications. “We encountered frustrating obstacles,” says team leader Carter, “like figuring out how to put a membrane the size of a human hair on a needle, finding a polymer that was strong enough to use, and determining the size of the rod.”

“The thing that was different about this team and why they won is that they took an actual product that looked as though it could literally be used in the clinic to solve a huge specific, clinical problem,” says Olson. “Their work ethic is amazing, and they were a pleasure to work with.”

Left to right: Harjit Kaur, Annicka Carter, Jeremy Hammer, and Nick Rejali

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Randall J olson, MD, Professor and Chair, Department of ophthalmology and Visual Sciences; Ceo, John A. Moran eye Center, was named the 2014 recipient of the Rosenblatt Prize for excellence. Presented annually to a faculty member who displays excellence in teaching, research, and administrative efforts, it is the U’s most prestigious award. University President David W. Pershing noted that “Dr. Olson has a long, rich history with the U and is an inspired choice for this honor. His forward-thinking leadership has effectively put the Moran Eye Center on the national map, bringing life-changing research and outreach, renowned patient care, and academic excellence together in one outstanding institution.”

“We could not be more proud that Randy Olson was awarded the Rosenblatt Prize this year,” said Vivian Lee, Senior Vice President for Health Sciences at the U. “His service as ‘visionary-in-chief’ has grown a department from its humble beginnings with two faculty members, to a globally acclaimed center for research, education, and clinical excellence. As an internationally renowned scholar and charismatic

leader, Randy’s contributions to the University of Utah are second to none. University of Utah Health Sciences and the Moran Eye Center are fortunate to be the beneficiaries of his stellar acumen.”

“He has created a culture of collaboration and excellence that is the envy of so many departments,” said David Chang, Clinical Professor of Ophthalmology at the University of California at San Francisco, and International Committee Chair, American Society of Cataract and Refractive Surgery. “He is one of the most influential and prominent academic chairs in ophthalmology. His selection as president of the Association of University Professors of Ophthalmology is a testament to his stature in our field.”

Additionally, Olson was honored in 2012 with the Binkhorst Medal at the American Society of Cataract and Refractive Surgery, an award dedicated to excellence in intraocular lens research.

m o r a n e y e c e n t e r A W A R D S

Hedi Fritz-Niggli Visiting Professor

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Iqbal “Ike” K. Ahmed, MD, PhD, received the 2014 binkhorst Medal and presented the prestigious Binkhorst Lecture during the American Society of Cataract and Refractive Surgery Symposium and Congress in Boston on April 26, 2014. With this announcement, a Moran physician or alumni has received this most prestigious honor three years in a row. Ahmed is currently an assistant professor at the University of Toronto and a clinical assistant professor at the University of Utah, where he completed a glaucoma and anterior segment fellowship at the Moran Eye Center.

Binkhorst Medal

Kathleen b. Digre, MD, broke new ground as the first hedi fritz-Niggli Visiting Professor at the University of Zurich. This is a great honor for Dr. Digre and for Moran, as she worked with the University of Zurich—in residence from February through July 2014—laying groundwork for future visiting professors, finding and promoting more women faculty and leaders, lecturing, and sharing Moran’s work in research, patient care, and education.

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Krista Kinard, MD, Moran Neuro-ophthalmology fellow, trumped tough competition to receive the “best Abstract by a fellow Award” at the North American Neuro-Ophthalmology Society’s 40th Annual Meeting. Her abstract, “Chronic Migraine is Associated with Reduced Corneal Nerve Fiber Density and Length,” was entered in the “Posterior Afferent Visual Pathway (Post-Chiasmal)” category. Kinard’s additional areas of training and specialization include ultrasound of the orbit and electrophysiology techniques.

“Best Abstract by a fellow Award”

Alan S. Crandall, MD, was honored with the 2014 Dr. Clark lowe Rich Distinguished Surgeon and Mentor Award recognizing “an outstanding surgeon who has demonstrated exceptional skill and dedication in the fields of surgery, including teaching, advising, and mentoring medical students, interns, residents, or fellows at the University of Utah.” Dr. Crandall is the John A. Moran Presidential Professor and Senior Vice-chair of Ophthalmology and Visual Sciences, Director of Glaucoma and Cataract at the Moran Eye Center, and Co-director of the Moran Eye Center Outreach Division.

A member of the class of ‘73, Dr. Crandall was also honored as a Distinguished Alumni by the University of Utah School of Medicine Alumni Association at the School of Medicine Annual Awards Banquet and Half-Century Celebration on Oct 10, 2013. he also received the 2014 outstanding humanitarian Service Award from the American Academy of ophthalmology.

Dr. Clark Lowe Rich Distinguished Surgeon and Mentor Award

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Ludwig von Sallmann Clinician-Scientist Award

balamurali K. Ambati, MD, PhD, MbA, was honored with the 2014 ludwig von Sallmann Clinician-Scientist Award by the Association for Research in Vision and ophthalmology (ARVo) foundation for eye Research. This award is in recognition of Ambati’s contributions to the field of ophthalmology. Ludwig von Sallmann, MD, who served as Chief of the Intramural Program of the National Eye Institute, was an ARVO Proctor Medal recipient. Ambati also was invited to join the judge’s panel for the prestigious INtel Science talent Search. Eight winners or finalists of this competition have gone on to win Nobel prizes. This honor is one of many that highlight Dr. Ambati’s extraordinary career as a researcher and a physician and his dedication to mentoring the next generation of scientists.

John bloomberg was named honorary Alumnus by the University of Utah. Bloomberg, who holds a bachelor’s degree from Amherst College and a Masters of Business Administration from Harvard University, is a former Wall Street research analyst and competitive skier. After his vision began rapidly deteriorating, he was introduced to the U’s Department of Ophthalmology where he met Dr. Randall J Olson. In gratitude for surgery that Bloomberg has credited with saving his vision, he and his wife, Toni, have generously contributed to the Moran Eye Center. John Bloomberg is a long-time member of the John A. Moran Eye Center’s Advisory Board.

honorary Alumnus

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My Life Has Made Me an Expert on Blindness

Ten times a year, groups of all ages gather for a Moran “Orientation to Vision Loss Seminar”— part of Moran’s groundbreaking Patient Support Program designed to address the psychosocial impacts of vision loss.

One by one, their stories unfold. A 50-something woman experiencing vision loss from a series of unsuccessful surgeries tears up as she chronicles her feelings of confusion and frustration. An 89-year-old man has to stop driving because a gradual form of age-related macular degeneration is robbing him of the ability to see clearly. As each person speaks, longtime seminar volunteer, 43-year-old Corinna Trujillo Tanner, RN, MSN, nods thoughtfully. And then she stands up, white cane in hand, and tells her story.

As a young girl in rural Colorado, Tanner was diagnosed with a rare form of Stargardt’s disease (type 3), an incurable, hereditary form of blindness. “But my family didn’t know what to do,” she says. “Out where we lived, there were zero resources for visually impaired or blind people. So I got a pair of my dad’s hunting binoculars and took them to school so that I could see the blackboard.” And that was just the beginning of her determined path. A move to California and a scholarship from the National Federation for the Blind helped change her life. Now, even as she juggles her PhD work, marriage, a new baby, and fulltime work as a rehabilitation teacher at The Blind Center, her life’s work is empowering others with vision loss.

“I want people to know that even if you are blind, you can have a great life. You can be a mom, wear makeup, go to school, and play the violin. It’s possible to reduce vision loss to the level of ‘nuisance’ instead of letting it change your life. And I can say that because my life has made me an expert on blindness.”

Learn more about Moran’s Patient Support Program http://healthcare.utah.edu/moran/outreach/patient_support_services.php

Corinna Tanner is a long-time volunteer with Moran’s Patient Support Program

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Imagine suffering from devastating headaches, blind spots, double vision, and sometimes, episodes of complete blindness. An estimated 100,000 Americans have been living with such symptoms for years.

They are victims of a disorder called idiopathic intracranial hypertension (IIH)—elevated spinal fluid pressure in the brain. Also called pseudotumor cerebri, it predominately affects overweight women of reproductive age, and when it strikes, it can take away the ability to carry out the simple tasks of daily living. Unfortunately, IIH is often difficult to diagnose, and its exact causes are unknown.

Now, relief is in sight. A recent study funded by the National Institutes of Health revealed that the use of an inexpensive glaucoma drug (acetazolamide), when added to a weight reduction plan, can improve and even restore vision for women with IIH. Moran neuro-ophthalmologists Drs. Kathleen Digre, Judith Warner, and Bradley Katz participated in the study published in April 2014 in the Journal of the American Medical Association.

Challenges and SolutionsThanks to an alert ophthalmologist, Sarah Reed found hope as one of the study’s subjects. “I had an intense episode of headaches and neck pain that lasted for about three weeks,” she says. “I was seeing double, though I really didn’t realize it for a couple of weeks because my eyes were so sensitive I scrunched them up most of the time.” While suffering head and neck pain, she visited a chiropractor who didn’t know what to make of her symptoms. Another doctor prescribed

Relief in Sightidiopathic intracranial hypertension:

Sarah and her canine pal, Leo

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antibiotics in case she had a sinus infection. “When the headache finally stopped, I realized I was seeing two of everything,” she remembers. She then consulted with an ophthalmologist who recognized her condition at once, was aware of the study, and called the Moran Eye Center. By the time Reed met Drs. Katz and Warner, her vision had gone back to normal, but she still had a constant “whooshing” sound in her ears—another typical indication of elevated pressure.

“Since taking the medication and losing weight—almost 30 pounds—I feel so much better, and the whooshing sound finally disappeared,” she reports. Reed is now back to doing what she loves, including hiking with her beloved English Mastiff, Leo, playing golf, and going to the movies.

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One of the greatest strengths of Moran’s resident training program is our high level of supervision and teaching: residents are outnumbered approximately three to one by full-time clinical faculty who have active practices covering all subspecialty areas of ophthalmology. Because residents interact with all of our patients, they have an opportunity to learn about and treat all ophthalmic conditions. As with any vibrant program, the characteristics, qualities, dedication, and work ethic of the person bringing it to the table can either make or break its success. For Moran, ferreting out these quality individuals begins with its unique recruitment process—and that process begins with Chief of Neuro-ophthalmology and Resident Selection Committee Chair, Dr. Judith Warner—who, with the heady obligation to “shape the future ophthalmologists of our world,” has for eight years painstakingly fine-tuned the process.

the Recruitment ProcessAfter personally reviewing nearly 400 resident applications each year, Dr. Warner and the selection committee choose 28. “Academic requirements are strict: applicants must show longitudinal academic achievement, have excellent test scores, have a sustained interest in ophthalmology, show an indication that they are socially interested, and display a research interest,” says Warner. “And just as importantly, we look for nice people who can get along with their fellow residents—people who are good team players and who help people out when there is not a direct quid pro quo. Sometimes, there is much more going on in a patient’s life that is impacting their sense of well-being. Sometimes, my job entails just telling patients that they are going to be ok—that they won’t go blind, that they are not going crazy, and that they will get through it,” states Warner. “I’m trying to find future ophthalmologists who will take good care of patients. Right now, we have the best residents in the country—they are smart, they are accomplished, and they are kind—I’m very proud.”

Moran’s Unique, Finely Tuned Resident Selection Committee:

Judith Warner, MD, Shaping Future Ophthalmologists of the World

Judith Warner, MD

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nda AGENDA: RESIDENT INTERVIEWS OCCuR FOuR

TIMES EACH FALL

NIGHT BEFORE: Dinner out with current residents—hugely positive!

MORNING OF: Breakfast; tour of Moran, Salt Lake, and one of the stunning Wasatch canyons.

PRE-LuNCH: Moran’s Outreach Division presentation by Dr. Craig Chaya.

LuNCH: Every faculty member, resident, and fellow who is available attends.

AFTERNOON: Formal interviews with Moran Chair and CEO, Dr. Randall J Olson and Residency Director, Dr. Jeff Pettey; formal interviews with selection committee members Drs. Judith Warner, Rachael Jacoby, David C. Dries, Balamurali K. Ambati, and Zachary Joos, ophthalmology resident.

HOME-BASE ROOM—APPLICANTS WAITING ROOM BETWEEN INTERVIEWS: They see running surgical video feed; are visited by faculty, staff, and residents, all of whom are able to answer questions; and are taken for more tours of the research facilities and path lab.

From left to right: Drs. Brian Zaugg, Zachary Joos, Brian Stagg, Trent Richards, Judith Warner, Dan Bettis, Julia Byrd, Adam Jorgensen, Leah Owen, Russell Swan, Rene Choi, Jim Bell, Eileen Hwang

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During her cornea fellowship at the Moran Eye Center, Valli Muthappan, MD, has performed LASIK and cornea transplant surgeries, treated corneal ulcers, and assisted in a groundbreaking telescopic lens implant surgery performed by Dr. Majid Moshirfar. The surgery was the first of its kind in Utah—a telescope implant that offers new hope to some patients with end-stage age-related macular degeneration. She’s also participated in several of Moran’s local outreach programs, such as volunteering at Salt Lake’s Maliheh Free Clinic. In May, she traveled to Haiti with Dr. Craig Chaya and a Moran outreach team to perform cornea transplants made possible with donated tissue from the Utah Lions Eye Bank. Their patients were the first in the region to receive this life-changing surgery.

On the final stretch of her fellowship, she says one of the most rewarding aspects of her experience is “having such an immediate impact on people’s lives. People who couldn’t see their clock in the morning without their glasses come in for LASIK or cataract surgery, and as soon as we take the patches off their eyes, there’s a huge grin—instant gratification!”

After completing her residency at the Wilmer Eye Institute at Johns Hopkins University in Baltimore, Muthappan knew she wanted to come to Moran “because everyone knows it by reputation; it’s one of the best cornea fellowships in the country.” She chose to specialize in ophthalmology and corneal surgery in particular, “because in addition to being able to deliver immediate results, you can establish long-term relationships with patients as you take care of their changing vision needs over time.”

Born and raised in Pittsburgh, Pennsylvania, Muthappan will return to her home city where she has accepted a position as a cornea specialist in private practice. “Happily,” she notes, “my childhood eye doctor said he can’t wait to start referring patients to me!”

Cornea Fellowship: Valli Muthappan, MD

“We Can Have Such an Immediate Impact on Patients’ Lives”

The Moran Eye Center offers ophthalmology fellowship programs in cornea and refractive (LASIK) surgery; glaucoma; neuro-ophthalmology, and retina. We also offer an international fellowship for US citizens who work with Dr. Geoffrey Tabin at the Moran Eye Center as well as in several developing countries. For more information, please contact the Department of Ophthalmology and Visual Sciences Academic Office at 801-585-6701.

Moran Fellow, Valli Muthappan

Examining a patient prior to surgery in Haiti Photo credit: OneMoreGeneration.org

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Jim Bell, mDnikhil Batra, mD

rene choi, mD, PhD eileen Hwang, mD, PhDJulia Byrd, mD

Consistently Ranked as One of the Top 10 Ophthalmology Education Programs in the NationFor over 30 years, the ophthalmology program at the University of Utah School of Medicine has offered excellent didactic

training and extensive surgical experience. Each year, faculty from the Moran Eye Center provide ophthalmology training

to approximately 70-80 medical students and visiting residents as well as three interns, nine residents, seven to eight

fellows, and many international observers. As the only medical school in the Intermountain area, the University of Utah

plays an important role in training the region’s next generation of physicians and ophthalmologists.

S E C O N D y E A R

Fellowship program 2014-2015

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residency program 2014-2015

F I R S T y E A R

adam Jorgensen, mD Brian Stagg, mD russell Swan, mD

T H I R D y E A R / C H I E F R E S I D E N T S

carlton Fenzl, mD

Hari Bodhireddy, mDDan Bettis, MDtrent richards, mD Brian Zaugg, mDZachary Joos, mD

reuben Valenzuela, mD

anya Gushchin, mD

NEuRO- OPHTHALMOLOGy

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FELLOWSHIP

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A superb overall experience With 12 locations and four state-of-the-art ophthalmic surgery suites, over 40 ophthalmology specialists carry out more than 6,500 surgeries per year at the Moran Eye Center. This ensures that residents and fellows have ample opportunity to participate in a full spectrum of clinical and surgical experiences.

Located at the base of the spectacular Wasatch Mountains, the University of Utah is the flagship institution of higher education in Utah. Within reach of seven major ski resorts, gorgeous desert country, and a population known for its friendliness, Salt Lake continues to rank among the top cities in which to live.

interns & ophthalmic pathology/ research Fellows 2014-2015

ashlie Bernhisel, mD christopher conrady, mD, PhD

richard “reese” Feist, Jr., mD

aabid Farukhi, mD Gregory Kramer, mD Kyle macLean, mD

I N T E R N S

O P H T H A L M I C P A T H O L O G y / R E S E A R C H

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The Moran Eye Center offers ophthalmology fellowship programs in cornea and

refractive surgery, glaucoma, neuro-ophthalmology, retina, and Moran international.

For more information, please contact the Department of Ophthalmology and Visual

Sciences Academic Office at 801-585-6701.

Wyatt Messenger, MD ruju rai, mD

R E S E A R C H F E L L O W S

R E S I D E N T S A N D F E L L O W S

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CEO of the John A. Moran Eye CenterRandall J Olson, MD, is the chair of the Department of ophthalmology and Visual Sciences and ceo of the John A. Moran Eye Center. Dr. Olson is the author of more than 300 professional publications and a worldwide lecturer. He specializes in research dealing with intraocular lens and cataract surgery. He was selected as the Binkhorst Medal recipient in 2012 by the American Society of Cataract and Refractive Surgery, has given many named lectures all over the country, and was selected in 2014 by the University of Utah for the Rosenblatt Prize for Excellence. Time constraints limit the number of patients Dr. Olson is able to see, yet he continues to enjoy patient care visits on a regular basis.

specialty• Cataract Services and External Eye Diseases

Doctors in Alphabetical Order

Balamurali K Ambati, MD, PhD, MBA, specializes in cornea transplants, cataract extraction, keratopros-thesis (artificial cornea), LASIK, and other complex procedures of the cornea and anterior segment of the eye. He welcomes patients in these areas as well as general ophthalmic issues. Dr. Ambati also maintains a dynamic research laboratory and has authored more than 40 peer-reviewed publications and two books.

specialties• Cornea• Cataract Services• Vision Correction Surgery (LASIK, Laser, and Non-laser)• Uveitis

Paul S Bernstein, MD, PhD, specializes in age-related macular degeneration with special em-phasis on the role of nutrition and environment in its treatment and prevention; inherited retinal and macular dystrophies; and surgical treatment of vitreoretinal disor-ders such as diabetic retinopathy and retinal detachments.

specialties• Vitreoretinal Diseases and Surgery • Retinal Biochemistry• Macular and Retinal Degeneration

Alan S Crandall, MD, is the Senior Vice chair of the Department of ophthalmology and Visual Sciences, Director of moran’s Glaucoma and Cataract Division, Co-director of Moran’s International Outreach Division, the Val A. and Edith D. Green Presidential Endowed chair in ophthalmology, and past president of the american Society for cataract and refrac-tive Surgery. He focuses on the medical and surgical manage-ment of glaucoma and cataracts. Dr. Crandall has experience with trabeculoplasty and laser cyclo-photocoagulation. He is involved in numerous clinical research studies at the moran eye center, lectures throughout the world, and was selected by Cataract and Refractive Surgery Today as one of 50 international opinion leaders.

specialties• Cataract Services• Glaucoma

Susan Chortkoff, MD, focuses on the management and treatment of glaucoma as well as comprehensive ophthalmology. Dr. Chortkoff also has a special inter-est in the management of dry eye syndrome.

specialties• Comprehensive Ophthalmology• Glaucoma

William Barlow, MD, specializes in comprehensive ophthalmology with a focus on the surgical management of routine and complex cataracts, anterior segment surgery, and vision cor-rection surgery using laser and intraocular lenses. His current research interest is focused on cataract surgical outcomes.

specialties• Comprehensive Ophthalmology• Cataract Services• Refractive Surgery (LASIK, Laser, and Non-laser)

Craig J Chaya, MD, practices comprehensive oph-thalmology and specializes in the medical and surgical management of adult and pediatric cataracts, glaucoma, and anterior segment surgery. Dr. Chaya particularly enjoys teaching and is actively involved in Moran’s ophthalmology resident and glaucoma fellow train-ing programs. He is also passionate about local and international out-reach with his current work focus-ing on the advancement of eye care delivery in Haiti, Guam, Micronesia, Ghana, and the Navajo Nation in southern Utah. His research interests include the management of cataracts and glaucoma in the developing world and glaucoma surgical techniques and devices.

specialties• Comprehensive Ophthalmology• Cataract Surgery• Glaucoma

2014m o r a n e y e c e n t e r O P H T H A L M O L O G I S T S

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m o r a n e y e c e n t e r O P H T H A L M O L O G I S T S 2014

David C Dries, MD, provides medical and surgical care for a wide range of eye diseases and visual impairments in children as well as evaluation and management of strabismus in both children and adults. His special interests include amblyopia, esotropia, exotropia, retinopathy of prematurity, retinoblastoma, infant and childhood cataracts, and nasolacrimal duct obstruction.

specialties• Pediatric Ophthalmology• Adult Strabismus

Joseph L Hatch, MD, provides expertise and experience in all areas of ophthalmology and has extensive experience in con-tact lens fitting. In 2008, Dr. Hatch was asked to serve on the Church of Jesus Christ of Latter-day Saints Vision Initiative. This program sends eye care professionals to countries throughout the world.

specialty• Comprehensive Ophthalmology

Roger P Harrie, MD,practices comprehensive oph-thalmology and ocular surgery with a subspecialty in ophthalmic ultrasound. He has been the senior instructor in the ocular ultrasound course at the annual american academy of ophthalmology meet-ing and has published numerous articles, book chapters, and two textbooks. Dr. Harrie has made more than 20 humanitarian trips, mostly training doctors in develop-ing countries in diagnostic and therapeutic techniques. He directs the outreach program in examin-ing and giving glasses to residents of the Salt Lake Valley youth Detention Center.

specialty• Comprehensive Ophthalmology

Mary Elizabeth Hartnett, MD, is Director of Pediatric Retina. She specializes in vitreoretinal surgery and directs a pediatric retina center, managing both pediatric and adult retinal conditions at the moran eye center. She performs surgery at both the moran eye Center at the University of Utah and the moran eye center at Primary children’s Hospital.

specialty• Pediatric and Adult Retinal Diseases and Surgery

Alison Crum, MD, specializes in both oculoplastics and orbital surgery—the recon-struction of the bones around the eyes after traumas, cor-recting drooping eyelids, and aesthetic surgeries, such as eyelid lifts. She also practices neuro-ophthalmology, the study of how the eye connects to the brain, and provides medical and surgical treatments for visual disorders. Her interests include treatment of Graves’ disease and treatment of papilledema.

specialties• Neuro-ophthalmology• Oculoplastics and Facial Plastic Surgery• Ophthalmology

Kathleen B Digre, MD, is a past president of the north american neuro-ophthalmology Society. She specializes in neuro-ophthalmology and evaluates and treats complex visual complaints which can be due to optic nerve or brain disease. Her interests include gender differences in neuro-oph-thalmic disorders, pseudotumor cerebri, ischemic optic neuropathy, temporal arteritis, papilledema, episodic vision loss, headaches and eye pain, diplopia, and Graves’ disease. She has worked with the north american neuro-ophthal-mology Society and the University of Utah Eccles Library to develop a neuro-ophthalmology Virtual Educational Library (NOVEL) online at http://novel.utah.edu. She received the Rosenblatt Prize for Excellence at the University of Utah in 2012.

specialty• Neuro-ophthalmology

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Nick Mamalis, MD, is Director of the ophthalmic Pathology Laboratory and evalu-ates all specimens submitted to the laboratory. He focuses his clinical practice on comprehensive ophthalmology including cataract and other anterior ocular surger-ies. Dr. mamalis is the editor of the Journal of Cataract and Refractive Surgery and is the author of 190 peer-reviewed publications, one textbook, and 40 book chapters. He is also co-director of the Intermountain Ocular Research center and is performing research in the area of intraocular lenses and postoperative inflammation. Dr. mamalis lectures throughout the world and was selected by Cataract and Refractive Surgery Today as one of 50 international opinion leaders. He was selected as the Binkhorst medal recipient in 2013 by the american Society of Cataract and Refractive Surgery.

specialties• Cataract Services• Ophthalmic Pathology• Comprehensive Ophthalmology

Mark D Mifflin, MD, is moran’s Director of Surgical Services and the Medical Director of the Utah Lions Eye Bank. He specializes in the medical and surgical treatment of corneal and anterior segment eye diseases. His expertise includes all types of corneal transplantation, cataract surgery, and refractive surgery.

specialties• Cornea Transplant Surgery (Penetrating Keratoplasty, Lamellar Keratoplasty, Stem Cell Transplantation, and Eye Banking)• Cataract Surgery (Premium Intraocular Lenses, Monovision)• Vision Correction Surgery (LASIK, PRK, Phakic Intraocular Lenses)

Majid Moshirfar, MD, FACS, is the Director of moran’s cornea and Refractive Surgery Division, Director of the Cornea Educational Fellow-ship, and co-medical Director of the Utah Lions Eye Bank. He special-izes in corneal transplantation, keratoprosthesis (artificial cornea), management of difficult corneal dis-orders, complicated cataract extrac-tion, LASIK, infectious eye diseases, and other complex procedures of the cornea and anterior segment of the eye. Dr. moshirfar lectures extensively around the country on a variety of vision correction proce-dures and has become a community spokesperson on the benefits and risks of vision correction surgery. He has appeared in the last three editions of Best Doctors in America. Dr. moshirfar has authored more than 150 peer-reviewed scientific publications and five books and is on the editorial board of numerous ophthalmology journals.

specialties• Cornea Transplant (Penetrating Keratoplasty, DSAEK, DALK, Stem-cell Transplantation)• Vision Correction Surgery (LASIK, PRK, LASEK, Phakic IOL, Intacs, CK, Collagen Cross-linking)• Cataract Surgery and Intraocular Implants (Premium Intraocular Lenses, Monovision)• Dry Eye Disease (LipiFlow Treatment)• Corneal Infectious and Inflammatory Eye Diseases• Artificial Cornea• Implantable Miniature Telescope for Age-related Macular Degeneration

Bradley J Katz, MD, PhD, specializes in neuro-ophthal-mology, cataract, and com-prehensive ophthalmology. He evaluates patients with diseases that affect the optic nerve and diseases of the brain that affect vision and eye movements. Dr. Katz also conducts research in the areas of giant cell arteritis, photophobia and migraine, optic neuritis, and multiple sclerosis.

specialties• Cataract Services• Neuro-ophthalmology

Rachael Jacoby, MD, specializes in medical and surgical diseases of the retina and vitreous. Her primary clinical and surgical interests include retinal detach-ments, diabetic retinopathy, and macular and retinal degeneration.

specialties• Retinal Diseases and Surgery• Macular and Retinal Degeneration

m o r a n e y e c e n t e r O P H T H A L M O L O G I S T S

Robert O Hoffman, MD, is Chief of the Division of Pediatric ophthalmology and eye muscle Disorders. He has special interests in retinopathy of prematurity, ocu-lar genetics, craniofacial disorders, pediatric cataracts, and compli-cated strabismus.

specialties• Pediatric Ophthalmology• Adult Strabismus

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Jeff Pettey, MD, is Director of the John a moran eye center training and residency Program. He is also the chief of ophthalmology at the Salt Lake City VA Medical Center. Dr. Pettey specializes in comprehensive ophthalmology, complex cataracts, and anterior segment surgery. He coordinates teaching and training of medical students, residents, in-ternational observers, and fellows and is actively involved in local outreach and international oph-thalmology, working to develop teaching and training collabora-tions with programs in developing countries. He is actively involved in research to make cataract surgery safer and more efficient.

specialties• Comprehensive Ophthalmology• Cataract Services

Albert T Vitale, MD, is Director of Moran’s Uveitis Division. He specializes in patients with diseases of the retina and vitreous. He is one of the only oph-thalmologists in the Intermountain West specializing in the diagnosis and treatment of uveitis and other infections and inflammatory diseases of the eye. His research interests include ocular manifesta-tions of systemic diseases, novel therapeutic agents, and new drug delivery systems in the treatment of ocular inflammatory disease, retinal vascular disease, and the pharmacotherapy of age-related macular degeneration. He is one of a few people in the country with dual training in ocular immunol-ogy and inflammatory disease and vitreoretinal surgery. Dr. Vitale is co-author of the definitive text on the subject, with Dr. c. Stephen Foster, entitled, Diagnosis and Treatment of Uveitis.

specialties• Uveitis, Ocular Infections• Retinal Diseases and Surgery

Judith E A Warner, MD, is chief of neuro-ophthalmology. She evaluates complex visual complaints, which can be due to optic nerve or brain disease, and provides treatment for these disorders. Her interests include diplopia, giant cell arteritis, papilledema, optic neuritis, episodic vision loss, idiopathic in-tracranial hypertension, ischemic optic neuropathy, and unex-plained vision loss.

specialty• Neuro-ophthalmology

Geoffrey Tabin, MD, is the John E. and Marva M. Warnock Presidential Endowed chair in ophthalmology and co-director of Moran’s International Outreach Division. He specializes in corneal transplantation, keratoprosthesis (artificial cornea), management of corneal disorders, cataract extraction, LASIK, inflammatory eye diseases, and other complex procedures of the cornea and anterior segment of the eye. In addition to his work in Utah, Dr. Tabin is working to develop eye care delivery in developing countries, including improving cataract and corneal surgery.

specialties• Cataract Services• Vision Correction Surgery (LASIK, Laser, and Non-laser)

Jean Tabin, MD, provides general vision care and comprehensive ophthalmol-ogy services at the Moran Eye center. Dr. tabin enjoys working in Moran’s Triage Clinic, treating patients, and teaching medical students and residents who are interested in learning more about ophthalmology.

specialty• Comprehensive Ophthalmology

Michael P Teske, MD, is Director of Vitreoretinal Diseases and Surgery. Dr. teske specializes in medical and surgical diseases of the retina and vitre-ous. His primary surgical interests include retinal detachment, prolif-erative vitreoretinopathy, diabetic retinopathy, retinopathy of pre-maturity, epiretinal membranes, macular holes, and posterior segment trauma.

specialty• Retinal Disease and Surgery

Kim Taylor, MD, practices comprehensive oph-thalmology and has extensive experience in fitting contact lenses. He has many years of experience in diagnosing and treating eye diseases of all kinds.

specialty• Comprehensive Ophthalmology

Bhupendra C K Patel, MD, FRCS, FRC, is an expert in the management of disorders involving eyelids, periorbital tissues, the lacrimal system, and facial bones, including fractures. His clinical research interests include thyroid disease, optic nerve disorders, orbital and eyelid tumors, blepharospasm, lacrimal surgery, and facial cosmetic surgery.

specialty• Oculoplastic and Facial Plastic Surgery

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Barbara M Wirostko, MD, has specialized fellowship training in glaucoma, treats glaucoma and comprehensive ophthalmology patients, and specializes in clinical research and drug development for glaucoma pharmaceutical therapies. Her research interest is in sustained delivery of therapeutics for ocular pathologies and in approaching glaucoma through non-intraocular pressure mediated approaches.

specialties• Comprehensive Ophthalmology• Glaucoma

Norm A Zabriskie, MD, is Vice chair and medical Director of Clinical Services and Director of Clinical Operations at the John A. moran eye center. He specializes in the medical and surgical treatment of glaucoma and cataracts. He has a research interest in the genetics of glaucoma.

specialties• Cataract Services• Glaucoma

Marielle young, MD, provides medical and surgical care for children with eye disease as well as adults and children with strabismus. Her clinical expertise includes the evaluation and treatment of amblyopia, strabismus, infantile and developmental cataracts, and nasolacrimal duct obstruction.

specialties• Pediatric Ophthalmology• Adult and Pediatric Strabismus Aparna Ramasubramanian, MD,

specializes in eye diseases in children as well as evaluating and treating strabismus in adults and children, including adjustable sutures. She is also trained in ocular oncology and has a special interest in pediatric eye tumors, especially retinoblastoma.

specialties• Pediatric Ophthalmology• Ocular Oncology• Adult and Pediatric Strabismus

NEW CLINICAL FACuLTy

Derek J Sakata, MD, is medical Director for anesthesia Services at the John A. Moran Eye Center. Dr. Sakata provides and directs anesthesia care for ophthalmic patients before, dur-ing, and after surgery. He also has a background in engineering and has been involved in medical device design and subsequent company startups. He continues to be involved in research into new medical device designs and drug delivery.

specialty• General Anesthesiology

Lisa Ord, PhD, LCSW, is Director of the ophthalmology-based Patient Support Program for people with visual impairment and their families. Services in this program include counseling, information and referral services, support groups, and the orienta-tion to Vision Loss Program.

specialty• Counseling Related to Vision Loss

Donnell J Creel, PhD, is Director of the electrophysiology Service at the John A. Moran eye center. the electrophysiology Service provides examinations including visually evoked poten-tials, full-field electroretinograms, auditory brainstem responses, electrooculograms, multifocal electroretinograms, and multifocal visually evoked potentials. These tests quantitate retinal, optic path-way, visual cortical, and brainstem auditory pathway function.

specialty• Electrophysiology

OTHER SPECIALTIES

m o r a n e y e c e n t e r O P H T H A L M O L O G I S T S 2014Ophthalmologists Continued

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m o r a n e y e c e n t e r O P T O M E T R I S T S

Bryan H Vincent, OD, specializes in ocular pathology and contact lenses.

Greenwood Health Center John A. Moran Eye Center

Colleen S Schubach, OD, specializes in contact lens services for all ages and vision therapy with a special emphasis on children.

Redstone Health Center

Craig M Smith, OD, specializes in children's vision, sports vision, contact lenses, and general optometry.

Greenwood Health Center

Timothy L Gibbons, OD, specializes in contact lenses, pediatrics, sports vision, and ocular disease.

Stansbury Health Center Westridge Health Center

Mark A McKay, OD, specializes in full-scope optom-etric care, including adult and pediatric care, contact lenses and job- or hobby-related visual needs.

John A. Moran Eye CenterMoran Vision Center at Old MillRedwood Health CenterWestridge Health Center

Robert H Corry, OD, specializes in ocular pathology, pediatric and general optometry, and contact lenses.

Redwood Health Center South Jordan Health Center

Opt

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Alan Morgan, OD, specializes in contact lenses and general optometry.

UUHC—Davis Vision Center

Clair R Palmer, OD, specializes in contact lenses.

Parkway Health Center South Jordan Health Center

Harald E Olafsson, OD, is the Director of contact Lens Services. He specializes in fitting contact lenses with particular interest in kerato-conus, pediatrics, and fitting traumatized eyes; eyes with severe or irregular astigma-tism; and he provides primary eye care for those who do or do not wear contact lenses.

John A. Moran Eye Center

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Balamurali K Ambati, MD, PhD, MBAProfessor of Ophthalmology and Visual Sciences and Adjunct Associate Professor of Neurobiology and Anatomyspecialtiesocular angiogenesis and corneal research

Alessandra Angelucci, MD, PhDProfessor, Ophthalmology and Visual SciencesspecialtyVisual Cortex Circuitry and Function

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Wolfgang B Baehr, PhD

Professor and Director, Michael M. Wynn Center for Inherited Retinal Diseases; Ralph and Mary Tuck Professor of Ophthalmology and Visual SciencesspecialtiesPhototransduction, the Retinoid cycle, and membrane Protein Transport in Photoreceptors; Biochemistry, molecular and cell Biology

Paul Bressloff, PhD

Adjunct Professor, Ophthalmology and Visual Sciences; Professor of MathematicsspecialtyModeling of Visual Cortex

Paul S Bernstein, MD, PhD

Director of Clinical Research and Associate Director of Research; Mary H. Boesche Professor of Ophthalmology and Visual SciencesspecialtiesVitreoretinal Diseases and Surgery; Retinal Biochemistry; Macular and Retinal Degeneration

Donnell J Creel, PhD

Research Professor, Ophthalmology and Visual Sciences

specialtyelectrophysiology

Jeanne M Frederick, PhD

Research Associate Professor, Ophthalmology and Visual SciencesspecialtyRetinal Cell and Molecular Biology

Margaret DeAngelis, PhD

Associate Professor, Ophthal- mology and Visual Sciences

specialtyGenetics, Genomics, and Systems Biology-based approaches to Pinpoint Disease causality inAge-related Macular Degeneration, Glaucoma, Myopia, Diabetic Retinopathy, Retinopathy of Prematurity, and co-occurring Diseases

yingbin Fu, PhD

Associate Professor, Ophthal-mology and Visual SciencesspecialtiesMacular and Retinal Degeneration; Gene Therapy; Phototransduction

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Sabine Fuhrmann, PhD

Associate Professor, Ophthalmology and Visual SciencesspecialtiesOcular Development; Retinal Pigment Epithelial cell Biology

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Building bridges from research to patient care

Helga E T Kolb, PhD

Professor (Emerita), Ophthal- mology and Visual SciencesspecialtiesRetinal Anatomy; Editor, Webvision www.webvision.med.utah.edu

David Krizaj, PhD

Professor, Ophthalmology and Visual SciencesspecialtiesRetinal Neurobiology; Calcium Regulation; Glaucoma

Bryan W Jones, PhD

Research Assistant Professor, Ophthalmology and Visual SciencesspecialtiesRetinal Degeneration Disorders; Retinal Neurotransmission and Neurocircuitry; Metabolomics

Werner Gellermann, PhD

Adjunct Professor, Ophthalmology and Visual Sciences; Research Professor, PhysicsspecialtySpectroscopy of Living Human tissue

Mary Elizabeth Hartnett, MD

Professor, Ophthalmology and Visual SciencesspecialtyRetinal Angiogenesis Relating to Retinopathy of Prematurity and age-related macular Degeneration

Gregory S Hageman, PhD

John A. Moran Presidential Professor, Department of Oph-thalmology and Visual Sciences; Executive Director, Moran Center for Translational MedicinespecialtiesThe Genetics and Assessment of Pathways Involved in the Etiology of age-related macular Degenera-tion; Retinal Cell Biology

Bradley J Katz, MD, PhD

Associate Professor, Ophthal-mology and Visual SciencesspecialtiesGiant Cell Arteritis; Photophobia and Migraine; Optic Neuritis; Multiple Sclerosis

Julia Kleinschmidt, PhD, LCSWProfessor (Emerita), Ophthal-mology and Visual SciencesspecialtyOrientation and Support Services for international ophthalmolo-gists training under the moran Eye Center’s Outreach Division

Edward M Levine, PhD

Associate Professor, Ophthalmology and Visual SciencesspecialtyRetinal Neurogenesis and Regeneration

Nick Mamalis, MD

Professor, Ophthalmology and Visual Sciences; Co-director, Intermountain Ocular Research CenterspecialtiesOcular Pathology; Comprehensive Ophthalmology; Intraocular Lens Research; Postoperative Inflammation

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Ning Tian, PhD

Professor, Ophthalmology and Visual SciencesspecialtyRetinal Neurobiology

Monica Vetter, PhD

Adjunct Professor, Ophthalmology and Visual Sciences; George and Lorna Winder Professor of Neuroscience; and Chair, Neurobiology and AnatomyspecialtiesRetinal Development; Glaucoma

Haibo Wang, MD, PhD

Research Assistant Professor, Ophthalmology and Visual SciencesspecialtyVascular Biology: abnormal vessel growth implicated in pathological neovascularization in age-related macular degenera-tion, retinopathy of prematurity, and diabetic retinopathy

Richard A Normann, PhD

Professor (Emeritus), Ophthalmology and Visual Sciences; Distinguished Professor of BioengineeringspecialtyArtificial Vision/Neural Prosthetics

Robert E Marc, PhD

Director of Research and Distinguished Professor of Oph-thalmology; Cal and JeNeal Hatch Presidential Endowed Chair in Ophthalmology and Visual SciencesspecialtiesRetinal Neurotransmission and Networks; Retinal Degenerations; metabolomics

Jun yang, PhD

Associate Professor, Ophthal-mology and Visual SciencesspecialtiesCell Biology of Photoreceptors; Retinal Diseases

Barbara M Wirostko, MD

Clinical Adjunct Associate Professor, Ophthalmology and Visual SciencesspecialtiesGlaucoma; Drug and Device Development

Liliana Werner, MD, PhD

Associate Professor, Ophthal-mology and Visual Sciences; Co-director Intermountain Ocular Research CenterspecialtiesOcular Biodevices Research; Dif-ferent Intraocular Lens Designs; Materials and Surface Modifica-tions; Interactions between Ocular Implants and Ocular Tissues

NEW RESEARCH FACuLTy Debra A Schaumberg, ScD, OD, MPHProfessor of Ophthalmology and Visual Sciences; Associate Director for Clinical and Epidemiological Research, University of Utah Moran Eye Center for Translational Medicine; Adjunct Professor of Epidemiology, Harvard School of Public HealthspecialtiesEpidemiology and the Joint Influences of Genetic, Molec-ular, and Lifestyle Risk Factors in Causing Eye Disease; Age-related Macular Degeneration; and Dry Eye Disease

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Moran eye Center in Your Community The Moran Eye Center provides comprehensive eye exams, fashion eyewear, and the latest contact lenses to meet all of your eye care needs. We have 13 locations along the Wasatch Front. Moran Community Clinics are typically located with a University of Utah Health Care Clinic, which provides a full range of world-class medical services.

✲ We’re excited to announce the opening of the NeW Midvalley health Center in spring, 2015. At that time, Moran’s Rocky Mountain ophthalmology, old Mill Medical Center, and Moran optometry and optical services at greenwood health Center will be incorporated into one convenient location at 243 east 6100 South, north of fashion Place Mall.

Moran Eye Center Doctors of Optometry

Robert H Corry, OD

Timothy L Gibbons, OD

Mark A McKay, OD

Alan Morgan, OD

Harald E Olafsson, OD

Clair R Palmer, OD

Colleen S Schubach, OD

Craig M Smith, OD

Bryan H Vincent, OD

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Contents

Donor Report 45

Industry Leadership and Service 51

Awards, Honors, and Appointments 54

Clinical Trials 56

Technology Commercialization and Intellectual Property/Patents 58

Grand Rounds 60

Published Research 62

Research Grants and Contracts 66

National and International Presentations 72

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gifts of $25,000 and above

Bamberger-Allen Health & Education FoundationJohn B. and Geraldine W.* GoddardNoel and Florence Rothman Family

Wattis Dumke Foundation

gifts of $10,000 and above

ARCS Foundation Inc., Utah ChapterBMW of Murray/Mini of MurrayWilliam BarrettJohn and Toni BloombergWilliam H. and Patricia W. ChildMargaret D. HicksHoya Medical Singapore PTE LTDSteven A. and Elizabeth M. HuishStephen C. and Lynda M. JacobsenJohnson FoundationRobert A. and Joan* Judelson

William C. Klintworth and Kimberly A. Perkins KlintworthMihail S. Lari and Scott E. MurrayClaudia Skaggs LuttrellMicroSurgical TechnologyThe Mark & Kathie Miller FoundationRalph P. and Marge NeilsonGordon and Marcia* OlchGlenn T. and Mary K. PotterWilliam K. and Julia D. ReaganHazel M. RobertsonRuvo Family FoundationPilar Pobil SmithDenise R. SobelJames M. Steele and Linda Lewis WolcottStrazza Family TrustO.C. Tanner CompanyHank and Sally TauberUtah Lions Foundation

gifts of $5,000 and above

David W. BeckerScott BergesonDale A. and Janeel O. BurninghamDavid and Kerry CarlsonJulie Crandall and Alan S. Crandall, MDLisa Z. and David A. Crandall, MDWilliam K. and Fern H. EnglandChip and Gayle N. EverestThomas H. and Carolyn L. Fey Carolyn Tanner Irish and Frederick Quinn, PhDPaul Joos, MDJames M. and Alison R. LuckmanJune MorrisNicholas & Company, Inc.Linda Rankin, PhDKhosrow and Ghazaleh Semnani

DonorsThe following individuals and organizations contributed to the Moran Eye Center from January 1, 2013 through December 31, 2013

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gifts of $1,000,000 a n d a b o v e

Elizabeth A. Johnson* | John A. and Carole Moran

gifts of $100,000 a n d a b o v e

Cumming Foundation | Edmund W. and Carol B. Dumke Research to Prevent Blindness, Inc.

Sharon E. Steele-McGee | Zions First National Bank

gifts of $50,000 a n d a b o v e

Alcon Research, Ltd. | Avis Badami The Lawrence T. and Janet T. Dee Foundation

Willard L. Eccles Charitable Foundation Peter and Nancy Salter | Marva M. and John E. Warnock, PhD

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Sam and Diane StewartMabel Wong*John A. and Robbin Yee

gifts of $1,000 and above

Aaren Scientific, Inc.Advanced Vision Science, Inc.George M. AhnBalamurali K. Ambati, MD, PhD, MBAA. Scott and Jesselie B. AndersonDavid R. and N.L. AndersonG.W.* and Ida Lee AndersonMarvin L. Arent*Ashton Family FoundationRalph L. AshtonDavid R. and Karen S. BachmanWolfgang B. Baehr, PhD and Jeanne Frederick, PhDBonnie BarryJoseph C. and Gainor L. BennettZachary BennettBennion JewelersWilliam F. and Victoria F. BennionPatricia Ann BergAnn P. and Paul S. Bernstein, MD, PhDCarol Berrey, PhDAlexander S. Bodi Revocable TrustEveline BruengerLaura D. ByrneRobert A. and Janette CarlsonRobert S. Carter Foundation, Inc.Irene G. CasperDavid J. and Marilyn C. ClarkKenneth D. CollinsChris ConnelleyCynthia ConnerRichard L. and Janice M. CorbinRobert W. and Carol N. CulverCycleSmithPaul and Sylvia DavisTim and Candace DeeCaren DixonJane Durcan, MD and John Hoffman, MD

Mountain Film in TellurideGeorge G. and Pauline MulliganMarilyn Neilson Elizabeth Ann NielsonMary NordRuth L. and Randall J Olson, MDChristoph and Jenny H. PalmanshoferReynold PalmerStephen and Marylyn PauleyJan J. RasmussenRon and Carolyn C. ReavelyRed Butte Lions ClubChris ReddishDon B. ReddishAlvin and Helene RicherEdward N. and Carol S. RobinsonWilliam L. RogersNancy H. SchwanfelderTueng T. Shen, MD and Jan H. ThijssenHelen SikesFred R. and Margo SilvesterHarris H. and Amanda P. SimmonsL.E. and Virginia Simmons FoundationFrances M. SlaytonJanet Hughie Smith, JDHoward S. Spurrier, DDSVerl H. Talbot, MDDavid O. TannerGretchen and Michael P. Teske, MDJames P. Tweeten, MDAlbert Vitale, MD and Patricia Vitale, MDM. Walker and Sue R. WallaceLuree and Robert C. Welch, MDDonald E. WestonJoleen WilleyDan and Lisa WilliamsonDavid R. WilsonJames R. and Linda R. WilsonWolf Eye Center, Inc.Workers Compensation FundHenry C. Wurts and Elaine EllisRobert C. and Patience Ziebarth

Greg and Carol A. EastonThomas H. and Laurie J. EastwoodGeorge S. and Dolores Doré Eccles FoundationFred W. and Christine A. FaircloughJoan B. and John H. Firmage IICecelia H. Foxley, PhD James R. and Barbara GaddisB. Greg GardnerMary Ann GardnerPanozzo GiacomoMichael Graham and Lucia M. LucciRobert M. GrahamAdrienne Graves, PhDGreater HorizonsLeah Hatziathanasiou and FamilyC. Charles and Elise HetzelCasey HillHoward Rodney HorinbeinJerry S. and Claudia F. HowellsJacobsen Lake FoundationThe Jarstad FamilyBrad, Tracey, Sam, Jonah and Zev KatzCharles and Laurel D. KayBenedict Kingsbury and Vivian S. Lee, MD, PhD, MBAMike and Kris KladisKuhlStephen LaneLegislative Insight Consulting LLCAllan M. and Kay W. LipmanJames L. and Carol C. MacfarlaneMaurice F. MaloufMercy and Nick Mamalis, MDBrent V. and Chris C. ManningMarmot Mountain, LLCRalph and Peggy P. McElvainDavid J. and Nancy L. McNallyVicki B. MerchantMolina Healthcare of UtahRuth A. MoreyDavid T. Mortensen and Rosemarie B. MayheraMimi B. Mortensen, JD

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Rodney W. and Christine S. DeckerKevin W. and Susan H. DeesingDenver Eye Surgeons, P.C.Carolyn Bartlett DeruCatherine R. deVries, MDSteven and Susan DeweySteve DeziiSonya Dhar, MDAnthony and Eileen Di BenedettoDavid M. DiamondLewis and Jyl DickmanBrian L. DiederichCameron Brady DiehlVera Caren DixonThe Dodo RestaurantRhonda E. and Mark K. Dodson, MDPhyllis L. DonleyDorsey & Whitney FoundationCurtis and Julie DrakeEzekiel R. and Analecia A. DumkeRobert D. and Danna EarlEast Millcreek Lions ClubJohn S. and Evelyn B. EdwardsRobert and LaDorna EichenbergRobert C. and Lisa B. EixenbergerJack and Melanie ElizondoShirley EllrichWillard G. and LaVon L. EricksonJim FangFarashaRichard A. and Carol M. FaySpencer P. Felt, Jr.Michael A. and Muffy M. FerroEugene M. and Sandra L. FerryCarol W. and John H. Firmage IIIWeston FirmageBruce R. and Carole E. FishburnKeith A. and Cindy H. FlemingJoseph H. and Pat FlorenceFlowriderFoothill Oriental RugsFrankie FordDiane Foster

gifts of $100 and above

G. Howard AbplanalpCurtis E. Ackerlind, Jr.Hans G. AhrensSylvan and Anita AlcabesAlcohol Servers Training of Utah, LLCStephen C. and Gena AlderRichard A. Aldous, MDAlpine Art & Frame, Inc.Ray W. and Bonnie Lou AlvordAlfred N. Andersen and Amy M. Ford AndersenMilton M. and Dianne K. AndersonRobert M. and Kathleen H. AndersonHarold and Dena AndrewsBarry J. and Catherine AngstmanVal R. Antczak and Barbara K. PolichMark and Christine M. ArchibaldPamela J. AtkinsonPatrick and Kathy BaccaBarry and Ann C. BagleyLeah A. BakerLinda BaldwinFern E. BartholomewBella Forte Clothing BoutiqueJohn E. BendixenKurt T. and Betsy BernhiselTed B. Bernhisel*Michael J. and Sharon M. BertelsenCarl M. BiehnBlack Diamond Equipment, Ltd.Bonnie B. BlanchardRobert L. and Anna C. BlissBodeen Ski & SportBrabar 1 BoutiqueBetsy T. BradleyDon F. and Jean W. BradshawRodney H. and Carolyn H. (Mitzi) BradyAlan H. and Marilyn M. BranchRichard and Diane BretzingMichael H. and Patty B. Brimley

Wallace B. and Patricia L. BrownBryce Lions ClubDolores Z. BuchananCaroline K. Buckway, MDRonald and Gloria BurletteRonald A. BurtonSally BurtonDan S. and Miriam BushnellFlorence Griffin ButlerDean CardinaleBob and Kim CarsonLee B. and Tammy CassityMichelle and Craig J. Chaya, MDThe Children’s HourGeorge A. and Pauline O. ChildsAndrew B. ChristensenChumsThe Church of Jesus Christ of Latter-day Saints FoundationJoann Coyte CisselGlenn D. and Kara E. Clapp, PhDG. Harlan and Mary Alice ClarkJames R. and Barbara S. ClarkMaurice V. and Marilyn S. CleggClif Bar & CompanyWhitney O. and Frances R. CluffJohn C. and Donna B. ColeRobert D. and Cheryl D. CookDrury W. Cooper IIIJody L. CopenhaverNicole Marie CottleA. Dennis CoxDavid L. CrandallF. Anthony and Joyce G. CrandallTerry CrandallR.L. CrawfordYue and Donnell J. Creel, PhDAlan S. and Joan E. CruickshankGreg J. CurtisRonny L. and Lindsay CutshallPhillip DavidsonSaundra D. DavisCraig W. Dayhuff

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Lewis Francis and Dana CostelloWilliam A. and Linda L. FrancisAnne FreedShelley M. FreemanL. Raymond and Mary F. FreerRichard K. Frerichs and Jean ZancanellaTaiko and Mitsuru FujinamiHeidi L. and Roger C. Furlong, MDJay and Lynda GambleThe Garden StoreDavid P. and Sheila S. GardnerJennifer GeorgeDevon M. and Julie H. GlennStephen L. and Leslie GoddardFred and Katharyn GonzalesMarianne GoodmanColleen GraceGrant FarmsJames E. and Ann GrayNeil J. and Stephanie D. GrayDonald R. and Susan GreenbergWilliam GreeneThe Group Real Estate, LLC.Marjorie Riches GunnDoug and Kristy GunnellJon and Lisa GuntherWilliam B. HaleDavid G. and Donna Ann HallJohn R. and Andrea M. HampshireCharles HanselJames W. and Karen L. Hansen Lynda HansenGerald D. and Betty Jo HansonHaroon’sLisa HarrisonMary Elizabeth Hartnett, MD and William H. Coles, MD Margaret A. HatchSusan D. Heath and William R. TannerWard H. Hedges, MDJohn B. and Jean M. HenkelsRuth A. Hensel

Eric Hermann and Susan Fredston-HermannJared and Jerusha HessHildegard L. HickmanBelva B. HigginsMargaret A. Hillyard-LazenbyEinar and Madora I. HoffCarolyn S. and Robert O. Hoffman, MDHome DepotJohn T. and Anne C. HopkinKenneth M. HowardAerste HowellJulie A. HowellVince HseihEdward L. Hughes and Roberta L. Anner-HughesJesse N. and Diane HunsakerGilbert H. and Thelma P. IkerWayne A. and Tina M. ImbresciaMarian W. InghamIntermountain BobcatJack Hegardt MasonryRachael Jacoby, MDJill JamesNick JarvisMartha Lewis JenningsJerry J. JensenNorman S. and Gail R. JensenJewish Communal FundJacqueline Townsend JollyRyan C. and Jaime L. JonesTravis and Megan JonesCarol A. JostK9 Cuts & Pupkulture BoutiqueKenneth P. and Julie P. KaiserPeter Kammeyer and Janeth R. Rouzer-KammeyerStephen C. and Uta I. KapplerDennis KellerRobert C. and Lindsay F. KellerJean L. KendallRichard A. and Kathleen O. KennedyJosephine S. Kimball

Lucinda KindredWilliam and Julia Kleinschmidt, PhDMarjorie W. and Jeffrey L. KuttererKatharine W. LambLandmark Title CompanyMarilee C. LattaMel and Wendy LavittDavid E. and Helane LetaFrank S. and Georgie E. LewisDon and Sue LewonRuth M. and Dean Y. Li, MD, PhDLiberty Heights FreshLifetime ProductsMatt LisenbySusan MacDonaldGeoffrey W. and Jonette C. MangumRobert E. Marc, PhD and Ann TorrenceWilliam A. MarshallSusan R. Massey and Lee E. Kapaloski, JD, PhDNorma W. MathesonWillard Z. and Rona Lee MaughanLes E. and Therese M. MayesBruce J. and Allyson B. McDonoughCameron McFarlandDaniel J. McInerneyRobert D. and Sandy McKeanPhilip M. and Susan L. McLaughlinJames and Heather McVeyLloyd R. and Marjorie R. MerrillMethod Communications, Inc.Virginia Biddle MeyerMark MiladCorey A. and Nancy J. MillerGerald and Cyndee L. MiyaLouis A. and Deborah MoenchMontgomery Fur Co.Moreton Family FoundationEdward B. and Barbara C. MoretonJudith S. MoretonTony and Mary Ann MorganVerna M. MorganMichael P. Morris

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Cory and Mimi SinclairNancy A. SinykinJonathan P. and Elizabeth M. SlagerAlbert H. SmallQuentin R. Smelzer, Jr.Marcie SnellPierre and Susan B. SokolskyDonna A. SonntagDonald A. and Hope R. SpitzIra E. and Patricia C. SteeleRonald E. and Julie SteeleStella and DotMarvin and Mary StilleWilna SwainEdward Harris SweetRonald and Kathleen H. SwitzerLary J. and Judy W. TalbotMary M. TalboysBarbara TalismanEarl TarverMark TaylorR. Burke TeichertTeleperformance USA GroupDavid B. TheobaldDave ThomasMary E. ThompsonBarbara TingeyBerdine TingeyJim and Candy TurnbullJon TweetenUnited ConcertsUtah Golf AssociationV ChocolatesJames H. and Rolande K. VaughnD. Jesse and Ann T. WagstaffGiles WallaceDennis B. WalshW. Jeffrey and Mona WaltersMatthew and Lynn WardJames C. WarenskiWashington Lions ClubCharles Weber, MD Jeanne A. Weber

Anna C. and Grant Morshedi, MDKim MosierWilliam N. and Elyce MouskondisMark J. and Katie MurphyNailedH.S. NakKenneth D. and Katie F. NaylorRonnie NaylorJames E. Nelson

Roland C. NickersonJohn T. NielsenKathryn NoahRichard A. Normann, PhD and Helga E. Kolb Normann, PhDJohn P. and Lisa O’BrienSuzanne E. OelmanStephen and Barbara OlchekLarry G. and Patricia H. OlsonEugene and Jean Overfelt The Owl and Fork ClubPaisley PomegranatePalettiMatthew R. and Karen ParsonsDinesh and Kalpana PatelLewis C. and Joanne PayzantKathy Jane and Donald M. Pedersen, PhDElaine PetersonRaymond R. and Judith C. PetersonGretchen and Jeff Hale Pettey, MDPETZL AmericaRobert W. and Celeste Y. PlassmanKeith G. and Beverly J. PolinoskiEsther PomeroyPorcupine Pub & GrillLynn PostnieksBrent and Tina PriceTaft and Mary Jane PriceBlanche B. PrisbreyJacqueline Kim PullosSusan J. Quaal, PhDSandie K. QuamV. Ramama and Elizabeth D. Rao

Waldemar E. and Harriet R. RasmussenJ. Scott and Debra S. RaymondDavid P. and Suzanne J. RazorREAL Salt LakeCory ReddishRedwood Pediatric DentistryRalph E. and Rita G. ReeseNicole ReimerRobert and Saundra F. RichardsonJeremy RobertsGlen A. Roser and Sherry S. Sabol-RoserRossignol Ski CompanyThe Rotary FoundationSaari Revocable TrustJohn M. and Melanie A. SaccoDavid E. SalisburySalomon USAThe Salt Lake Country ClubSalt Lake Lions ClubSalt Lake Running Co.W. Gary and Darcy E. SandbergPaul F. SargentTomako T. SchlagPaul E. and Diana F. SchmiedKim SchoenbrunnJohn F. SchrollSusan B. SchulmanSteven and Shelley SchwartzDavid M. and Debra R. ScottJeffrey K. and Sarah S. ScottMichael R. Scott and Loretta G. Falvo-ScottTrude Micheline SedlarWilliam and Amanda SelfTaymour SemnaniSephora—Downtown Salt LakeShaun Shafer, MDBrad and Mary L. ShepherdMartin A. and Pat ShermanAlan ShimizuGar ShurtleffDavid K. Sias

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Gene and Helen J. WecklerJeffrey R. and Anna M. WeisJonathan M. and Pamela C. WeisbergDavid M. Weiss and Linda BrillBart L. and Marlene G. WheelwrightMary Jo C. WightGregory P. and Daphne R. WilliamsH. James and Janet C. WilliamsStephen P. and Nancy Z. WilliamsJennifer Wilson and Trell RohovitBen and Suzanne J. WinchesterJudy WolfeRichard and Margaret WymanLouise M. and Norm A. Zabriskie, MDZAGG, Inc.

I N H O N O R O F

Those in whose honor gifts were made to the Moran Eye Center from January 1, 2013 through December 31, 2013

Marilyn AustinPaul Bernstein, MD, PhDBradJulie and Alan Crandall, MDBecky ChapmanThomas Clinch, MDNorris CookCarol FirmageCathleen FromeDonna Ann Hall Mary Elizabeth Hartnett, MDKate Harvey and Bob KemmeAlan E. HuishKim Corbin-Lewis and David R. LewisKirsten MallikNick Mamalis, MDErnie and Bonnie MesserlyMark D. Mifflin, MDRandall J Olson, MDMatthew Parsons, MDCharlie PieperGeoffrey Tabin, MDMichael Teske, MDMichael Yei

Norm Zabriskie, MD

I N M E M O R y O F Those in whose memory gifts were made to the Moran Eye Center from January 1, 2013 through December 31, 2013

All Eye DonorsLois Isabella AllredMarvin ArentWilliam ArmstrongFrances BallingGaylon BeanDick BennionAnnette BenzaquenTed BernhiselLee BronsonLaree Page BrownBarbara CallahanMarcela CalocaBrian A. ChristensenBeth Wilde ClementsLois CraneWilliam K. CraneWilliam C. CrockattJill CurtisColby EdwardsKeith Allen FillmoreDorothy HaddenCharles B. HamnerClark HardyThomas HarrisonSteven R. HohnkeLois HorneDavid HuberNorman C. JensenJohn KennedyAnn Zauhar LuceroM. Jack MacFarlandJay G. MacfarlaneCasey MarbleLloyd MarblePhillip McCollamMargene McFarlandEdith L. MeansR.W. “Web” MeansRobb Morris

David Ward MumfordWillard E. NelsonGarrett NicholsSteven NicholsMarva PastorinoAnna K. PiccoPhebe Wood PinderGeorge Cannon PingreeGene E. PinkermanMaurine PixtonElizabeth E. PorterEdmund M. RochfordJames W. ThompsonEllis VarnerJerald Ross WightLou Williams Mary D. WilliamsClarence WinbergShirley M. Zenger

*Deceased

The Moran Eye Center is grateful for the contributions made to support our mission and goals. We have made every effort to ensure that this 2013 Donor Report is as accurate as possible. Should you find an error or wish to change your listing, please contact us at 801-585-9700.

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Balamurali K Ambati, MD, PhD, MBA2008-Present Section Editor, Basic and Clinical Science Course in Ophthalmology, American Academy of ophthalmology

Alessandra Angelucci, MD, PhD2008-Present Review Editor, Frontiers in Neuroanatomy

2007-Present member, editorial Board, Visual Neuroscience

Review Editor, Frontiers in Systems Neuroscience

Wolfgang B Baehr, PhD 2013 editor, Vision Research, volume 53, (2012). Special Edition of the 14th Biannual Vision

editor, Journal of Ocular Biology, Diseases, and Informatics

2004-Present Senior Editor, Vision Research, Elsevier Science, San Diego, ca

Margaret DeAngelis, PhD 2013 Member, Admissions Committee, School of Medicine, University of Utah

Member, Executive Board, Women’s Eye Health.org

2011-Present member, Board of trustees, Fourth Street clinic

Kathleen B Digre, MD 2004-Present Chairman, Board of Directors, North American Neuro-Ophthalmologic Society

Chair, Publications Committee, American Headache Society

2002-Present Member, Review Board, American Headache Society

1998-Present Member, Board of Directors, North American Neuro-Ophthalmology Society

1995-Present member, editorial Board, Journal of Neuro-Ophthalmology

Gregory S Hageman, PhD 2013 Member, Advisory Board, Merck Sharp and Dohme Corp.

2013-Present Member, Ophthalmology Scientific Advisory Board, Applied Genetic Technologies Corporation

2012-Present Scientific Founder, Voyant Biotherapeutics LLC, Salt Lake City, UT

Member, Ophthalmology Clinical Advisory Board, Sequenom, Inc.

Member, Scientific Advisory Board, Foundation Fighting Blindness

2009-Present Member, Board of Directors, AMD Alliance International

Mary Elizabeth Hartnett, MD 2012-Present editor, american academy of Pediatric ophthalmology and Strabismus

member, editorial Board, Scientific World Journal

member, editorial Board, PlosOne

2011-Present editor, Molecular Vision and Molecular Vision Scientific Review

Board member, Women's eye Health.org

2009-Present member, editorial Board, Clinical Ophthalmology

Robert O Hoffman, MD 2011-Present Member, Medical Executive Committee, Primary Children's Medical Center

2007-Present Member, Legislative Committee, American Association for Pediatric ophthalmology and Strabismus

2003-Present Member, Alumni Board and Executive Committee, Ophthalmology and Visual Sciences, School of medicine

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2012Industry Leadership and ServiceThis is a partial list of Moran Industry Leadership and Service for 2013

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Rachael S Jacoby, MD 2012-Present Member, Institutional Review Board, University of Utah

Bryan W Jones, PhD 2002-Present Editor/Webmaster, Webvision http://webvision.med.utah.edu

Bradley J Katz, MD, PhD 2003-Present Committee Chair, Convention Management Committee, North American neuro-ophthalmology Society

Edward M Levine, PhD2007-Present editor, Journal of Ocular Biology, Diseases, and Informatics

2004-Present Member, Editorial Board, Developmental Dynamics

Nick Mamalis, MD2007-Present editor, Journal of Cataract and Refractive Surgery

1998-Present Member, Editorial Board, Review of Ophthalmology

Robert E Marc, PhD 2013-Present member, editorial Board, Journal of Comparative Neurology, Society for Neuroscience

Mark D Mifflin, MD 2005-Present Member, Faculty Executive Committee, Ophthalmology and Visual Sciences

Majid Moshirfar, MD, FACS 2012-Present member, editorial Board, Oman Journal of Ophthalmology

member, editorial Board, Journal of Cataract and Refractive Surgeons Consultation Section

2011-Present member, editorial Board, Scientific World Journal

2009-Present Member, Editorial Board, International Advisory Board, Middle East African Journal of Ophthalmology

Randall J Olson, MD 2012-Present Executive Editor, American Journal of Ophthalmology

member, editorial Board, Ophthalmologica

2002-Present Member, Advisory Boards, Advanced Medical Optics, Inc., Surgical Global, and Healon V

1983-Present Member, Executive Committee, Department Chairs' Collateral Group and Sciences Council, School of medicine

Bhupendra C K Patel, MD, FRCS, FRC 2007-Present Chief Section Editor, Plastic Surgery, British Journal of Ophthalmology

2006-Present Chief Section Editor, Plastic Surgery, EYE

2005-Present chief coeditor, ORBIT

2003-Present member, editorial Board, Evidence Based Eye Care

2002-Present editor, USA ORBIT

2000-Present member, editorial Board, Aesthetique

1999-Present member, editorial Board, Journal of Cranio-Maxillofacial Trauma

1996-Present Member, Medical Advisory Board, American Society of Ocularists

1991-Present member, editorial Board, Abstracts from the Literature for Ophthalmic, Plastic, and Reconstructive Surgery

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Debra Schaumberg, ScD, OD, MPH 2013-Present Member, Scientific Advisory Board, SARcode Bioscience Inc.

member, Board of Directors, tear Film and ocular Surface Society

2008-Present Member, Scientific Advisory Board, Mimetogen Pharmaceuticals

2002-Present Founding Member, Executive Committee, Women's Eye Health.org

Geoffrey Tabin, MD 2006-Present editor, Stedman’s Medical Dictionary

Monica Vetter, PhD 2011-present Member, Scientific Advisory Board, “Catalyst for a Cure 2,” Glaucoma Research Foundation

Albert T Vitale, MD 2006-Present Member, Faculty Executive Committee, Ophthalmology and Visual Sciences

Member, Editorial Board, Editorial and Writing Committee for Practicing Ophthalmologists, american academy of ophthalmology

Editor, Basic Science Course: Intraocular Inflammation, Uveitis, and Tumors for Focal Points, american academy of ophthalmology

Member, Faculty Executive Committee, John A. Moran Eye Center

2004-Present Member, Advisory Boards, Genentech, Inc. and Lucentis

Member, Uveitis Advisory Board, Aciont Inc.

2003-Present Member, Uveitis Advisory Board, Bausch & Lomb

Judith E A Warner, MD 2004-Present Member, Editorial Board, Neuro-Ophthalmology

Liliana Werner, MD, PhD 2013-present Coeditor, Quarterly Column, “Cataract/IOL Complications: Moran CPC Reports,” EyeWorld International

editorial Board, Brazilian Journal of Ophthalmology

2009-present Member of the Scientific Advisory Board of Powervision Inc., USA

Barbara M Wirostko, MD2011-Present Chief Medical Officer Retained Consultant, Altheos, Inc.

Executive Team Member, Lead Clinical Development Program and Glaucoma Strategy, Novel Rho Kinase Inhibitor, Currently in Phase 2

Ophthalmology Consultant and Member, Medical Advisory Board, Premier Research LTD.

Clinical Expert Advisor, Ophthalmology Drug Development

Chief Medical Officer and Strategic Advisory Board Member, SKS Biotech Incubator

Editorial Board, Grants Review Working Group, Acta Ophthalmologica

2009-Present america top ophthalmologist, Journal of Consumer Research

2007-Present Associate Editor and Peer Reviewer, Acta Ophthalmologica

Norm A Zabriskie, MD1999-Present Member, Faculty Executive Committee, Ophthalmology and Visual Sciences

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Awards, Honors, and Appointments

J O H N A . M O R A N E y E C E N T E R

2013-2014Other awards, honors, and appointments are highlighted in FOCUS content

Awards and Appointments

Balamurali K Ambati, MD, PhD, MBA, received the Troutman-Veronneau Prize, Pan-American Association of Ophthalmology, for his paper Raver2Preserves Cornea Avascularity by Inhibiting Splicing of the VEGF Decoy Recptor sFlt, 2013; he was also appointed to the Judge’s panel, INTEL Science Talent Search, 2013-2014

Margaret DeAngelis, PhD, was appointed to the editorial board of the Journal of Biophysical Chemistry

James Gilman, CRA, FOPS, was awarded First Place in the “Cross Category” section, Second Place in “Slit Lamp Photography” and in the “eye as art category” during the Ophthalmic Photographers’ Society Annual Scientific Exhibit at the American Academy of Ophthalmology, new orleans, 2013

Gregory S Hageman, PhD, received the 2014 Achievement Award, American Association of Ophthalmology

Mary Elizabeth Hartnett, MD, received the Women in Ophthalmology Scientific Contribution Award and Honorary Lecture Award, 2104; she was also appointed Chairperson to the Diseases and Pathophysiology of the Visual System Study Section at the Center for Scientific Review at the National Institutes of Health

Barbara M Wirostko, MD, was appointed to the Scientific Advisory Board of The Glaucoma Foundation

Amercian Society of Cataract and Refractive Surgery (ASCRS) Awards, 2014

Best Paper of Session: Brian E Zaugg, MD; cecinio ronquillo Jr.; Kevin Kirk; Brian C Stagg, MD; Jeff H Pettey, MD; William R Barlow, MD; Mohammed A. Farukhi; Isha Gupta; Randall J Olson, MD. Determining Optimal Longitudinal Power Setting for Torsional Phacoemulsification Using Ex Vivo Porcine Lens Model

Best Paper of Session: Jeff H Pettey, MD; Randall J Olson, MD; William R Barlow, MD; Brian E Zaugg, MD; Brian C Stagg, MD; Kevin Kirk; Cecinio Ronquillo Jr.; Jason D Jensen; Mohammed A Farukhi; Isha Gupta. Efficiency of Micropulse On-time Duty Cycle Settings

Best Paper of Session, Session 3-G: Justin C Kohl, MD; Joshua Ford, MD; Scott Cole, MD; Shail Vasavada, DO, DNB, FICO; Gareth Gardiner; Liliana Werner, MD, PhD; Nick Mamalis, MD. Long-term Uveal and Capsular Biocompatibility of a New Accommodating Intraocular Lens

Best Paper of Session, Session 3-Q: Joshua Ford, MD; Justin Kohl, MD; Scott Cole, MD; Gareth Gardiner; Shail Vasavada, DO, DNB, FICO; Liliana Werner, MD, PhD; Nick Mamalis, MD. Long-term Uveal and Capsular Biocompatibility and Stability after Nd:YAG Laser Posterior Capsulotomy of a New Disc-shaped Intraocular Lens

Scientific Poster, Honorable Mention, Intraocular Surgery: Liliana Werner, MD, PhD; caleb morris, erica Liu, mD, Shannon Stallings, mD, anne Floyd, mD. Light Transmittance of Cadaver-eye Explanted Single-piece Hydrophobic Acrylic IOLs with Surface Light Scattering

Best of Show, The Eye as Art: James Gilman, CRA, FOPS. Retinal Canopy

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Moran Faculty Featured at American Academy of Ophthalmology (AAO), New Orleans, November 19, 2013

PRESENTATIONS, PAPERS, POSTERS, & PANELS

Alan S Crandall, MD Preoperative Management of Medications. Early Postoperative Pressure Rise. Need for a Simultaneous Filter, presentation. M&M Rounds: Learning from My mistakes, panelist.

Gregory S Hageman, PhD Gene Markers and Prevention—Over the Horizon or Here Today? Presentation, Novartis Evolutions in Ophthalmology meeting.

Bryan W Jones, PhD Anatomy and Physiology of the Degenerating Visual System, presentation.

Nick Mamalis, MD Managing the Posterior Capsular Tear. Capsular Opacification with a New Silicone Oil-filled Accommodating IOL. Survey on Foldable IOLs Requiring Explanation or Secondary Inter-vention: ASCRS/ESCRS 2012 Update, poster, presentation. Prevention of Posterior Capsule Opacification. Accommo- dating IOL Update. Intraoperative Floppy Iris Syndrome. Cataract Surgery in Pseudoexfoliation Patients. Spotlight on Cataract Complications—M&M Rounds: Learning from my mistakes, panelist.

Randall J Olson, MD The Affordable Care Act and Health Care Reform 2013: How Will the AAC Affect Ongoing and Future Ophthalmic Research? Spotlight on Cataract Complications, panel member.

Geoffrey Tabin, MD Uptake of Free, High-quality Cataract Surgery among Bilaterally Blind Patients in Ethiopia, poster. Spotlight on Cataract Complications—M&M Rounds: Learning from my mistakes, panelist.

Liliana Werner, MD, PHD; Nick Mamalis, MD Localized Opacification of Hydrophilic Acrylic IOLs after Procedures Using Intracameral Injections of Air/Gas. Dr. Werner presented the paper, which was awarded “Best-Paper-of-Session” out of 300 entries in cataract original Papers category.

COuRSES Alan S Crandall, MD Advanced Refractive Cataract Surgery and Anterior Recon-struction—LenSx Femtosecond Laser Cataract Surgery. Cataract Surgery in the Setting of Ocular Comorbities and High-risk Features for Intraoperative and Postoperative Complications. Schlemm Canal Surgery. Tackling Weak Zonules and Using Capsular Tension Device. Clinical Decisions in the Management of Complications of Cataract and IOL Surgery. Catract Surgery Crisis Management 101.

Nick Mamalis, MD Astigmatism in the Cataract Patient Wet Lab. Cataract Surgery in the Setting of Ocular Comorbitities and High-risk Featurs for Intraoperative and Postoperative Complications. Phacoemulsification and Advanced Techniques: The Core curriculum cataract Surgery crisis management 101.

Randall J Olson, MD Why Learn Phaco Chop: Pearls and Pitfalls? Introduction to Horizontal chop.

Geoffrey Tabin, MD Manual Extracapsular Cataract Extraction Surgery: Indications and techniques. top 10 Hot corneal Surgical tips for 2013. Clinical Decisions in the Management of Complications of Cataract and IOL Surgery.

Albert T Vitale, MD Medical and Surgical Therapy and Diagnosis of Uveitis. How to Interpret Fundus Fluorescein Angiography and Autofluorescence.

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CATARACT Accuracy of the Holladay 2 Formula Using Lenstar Biometry Principal Investigator: James Bell, mD

Clinical Study of the ARTISAN Aphakia Lens for the Correction of aphakia in adults Principal Investigator: alan S crandall, mD

Clinical Study of the ARTISAN Aphakia Lens for the Correction of aphakia in childrenPrincipal Investigator: alan S crandall, mD

Refractive Index and Pseudophakic DysphotopsiaPrincipal Investigator: randall J olson, mD

Impact of AcrySof Glistenings on Visual QualityPrincipal Investigator: randall J olson, mD

Quality-of-Life Assessment in an Indigent Population Following cataract Surgery Principal Investigator: Jeff Pettey, MD

CORNEA Subconjunctival Aflibercept Injection for Corneal NeovascularizationPrincipal Investigator: Balamurali K Ambati, MD, PhD, MBA

collagenase-assisted Deep anterior Lamellar KeratoplastyPrincipal Investigator: Balamurali K Ambati, MD, PhD, MBA

Study Evaluating the Safety, Tolerability, and Efficacy of RU-101 Ophthalmic Solution in Patients with Severe Dry EyePrincipal Investigator: nick mamalis, mD

Effect of Corneal Preservation Time on Long-term Graft Success (CPTS)Principal Investigator: Mark D Mifflin, MD

Retrospective Study of Descemet's Stripping Automated Endothelial Keratoplasty outcomesPrincipal Investigator: Mark D Mifflin, MD

Evaluation of the Safety and Efficacy of Corneal Collagen Crosslinking in Eye with Keratoconus or Corneal Ectasia after Refractive SurgeryPrincipal Investigator: majid moshirfar, mD, FacS

Biomechanical Changes in the Cornea after Laser Assisted in situ Keratomileusis (LASIK) and Photorefractive Keratectomy (PRK)Principal Investigator: majid moshirfar, mD, FacS

Topical Proparacaine versus Tetracaine in Photorefractive Keratectomy (PRK)Principal Investigator: majid moshirfar, mD, FacS

GENERAL Experience in an Ophthalmology Clinic for Homeless PatientsPrincipal Investigator: Brian Stagg, mD

GLAuCOMA Observational Study Assessing Various Novel Vascular and Diagnostic Parameters and their Relationship to GlaucomaPrincipal Investigator: Barbara m Wirostko, mD

NEuRO-OPHTHALMOLOGy Prospective Assessment of Photophobia in Moran Eye Center PatientsPrincipal Investigator: Kathleen B Digre, mD

Evaluation of Optic Neuropathies with Imaging Principal Investigator: Kathleen B Digre, mD

Long-term Follow up of the Cohort from the Idiopathic Intracranial Hypertension Treatment Trial (IIHTT)Principal Investigator: Kathleen B Digre, mD

Retrospective Review of Primary and Secondary Causes of Pseudotumor cerebriPrincipal Investigator: Kathleen B Digre, mD

Measurement of Critical Flicker Fusion FrequencyPrincipal Investigator: Bradley J Katz, mD, PhD

Proteomics and Genomics of Giant Cell ArteritisPrincipal Investigator: Bradley J Katz, mD, PhD

Optic Nerve Drusen: Clinical Characterization and Genetic MappingPrincipal Investigator: Bradley J Katz, mD, PhD

Treatment of Giant Cell Arteritis with AntibioticsPrincipal Investigator: Bradley J Katz, mD, PhD

Prospective Study to Evaluate the Possible Association between the Use of PDE5 Inhibitors and the Risk of Acute Nonarteritic Anterior Ischemic Optic NeuropathyPrincipal Investigator: Bradley J Katz, mD, PhD

Predictive Value of Optic Nerve MRI Measurements at Onset of Optic Neuritis for two-year MS OutcomesPrincipal Investigator: Bradley J Katz, mD, PhD

Thin Film Spectacle Coatings to Reduce Light Sensitivity and Headaches in Patients with MigrainePrincipal Investigator: Bradley J Katz, mD, PhD

Benign Essential Blepharospasm in ChildrenPrincipal Investigator: Judith e a Warner, mD

Posterior Cortical AtrophyPrincipal Investigator: Judith e a Warner, mD

PEDIATRIC Genetics of Pediatric Retinal DisordersPrincipal Investigator: Mary Elizabeth Hartnett, MD

Preeclampsia and Retinopathy of PrematurityPrincipal Investigator: Mary Elizabeth Hartnett, MD

Genetic Associations in Preterm Infants at Risk of Retinopathy of PrematurityPrincipal Investigator: Mary Elizabeth Hartnett, MD

Currently, more than 70 clinical research trials are being carried out at the Moran Eye Center

C L I N I C A L T R I A L S 2013

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Spectral Domain OCT Imaging of Eyes: a Practical Diagnostic Tool and methodologyPrincipal Investigator: Mary Elizabeth Hartnett, MD

Postnatal Growth and Retinopathy of Prematurity Study (G-ROP)Principal Investigator: Robert O Hoffman, MD

Retrospective Analysis of Neurofibromatosis Type 1-associated Optic Glioma Outcome after TreatmentPrincipal Investigator: Robert O Hoffman, MD

Telemedicine Approaches to Evaluating Acute-phase Retinopathy of Prematurity (eROP)Principal Investigator: Robert O Hoffman, MD

Prevalence of Autism Spectrum Disorders in Patients with oculocutaneous albinismPrincipal Investigator: marielle young, mD

Pediatric cataract Surgery outcomes registryPrincipal Investigator: marielle young, mD

Clinical Phenotypes of Inherited Retinal DiseasePrincipal Investigator: marielle young, mD

RETINA Subretinal versus Intravitreal TPA for Subretinal HemorrhagePrincipal Investigator: James Bell, mD

Macular Pigment Imaging in Infants using the RetCamPrincipal Investigator: Paul S Bernstein, mD, PhD

Clinical Interventions against Stargardt Macular Dystrophy: DHA Supplementation in Patients with STGD3Principal Investigator: Paul S Bernstein, mD, PhD

Phase 3 Trial to Establish the Safety and Efficacy of Intravitreous Administration of Fovista Administered in Combination with LucentisPrincipal Investigator: Paul S Bernstein, mD, PhD

National Ophthalmic Genotyping Network (eyeGENE)Principal Investigator: Paul S Bernstein, mD, PhD

Utah Center for the Collaborative Study of the Role of Macular Pigment carotenoids in the Pathogenesis and treatment of mactelPrincipal Investigator: Paul S Bernstein, mD, PhD

Home Vision Monitoring in AREDS2 for Progression to Neovascular AMD Using the ForeseeHome DevicePrincipal Investigator: Paul S Bernstein, mD, PhD

Phase 2 Study to Investigate the Safety, Tolerability, Efficacy, Pharmacokinetics, and Pharmacodynamics of GSK 933775 in Patients with Geographic atrophyPrincipal Investigator: Paul S Bernstein, mD, PhD

Phase 2 Multiple-site Randomized, Placebo-controlled Trial of Oral Valproic Acid for Retinitis PigmentosaPrincipal Investigator: Paul S Bernstein, mD, PhD

Utah Center for MacTel GeneticsPrincipal Investigator: Paul S Bernstein, mD, PhD

Efficacy and Safety of Emixustat Hydrochloride (ACU-4429) with Placebo for the treatment of Geographic atrophy associated with Dry Age-related Macular DegenerationPrincipal Investigator: Paul S Bernstein, mD, PhD

natural History of the Progression of atrophy Secondary to Stargardt Disease: a Prospective Longitudinal Study (ProgSTAR)Principal Investigator: Paul S Bernstein, mD, PhD

natural History of the Progression of atrophy Secondary to Stargardt Disease: a Retrospective Longitudinal Study (ProgSTAR)Principal Investigator: Paul S Bernstein, mD, PhD

Effects of Maternal Nutrition and Intrauterine Growth Restriction on Infant Carotenoid StatusPrincipal Investigator: Paul S Bernstein, mD, PhD

Genetic and Epidemiological Study of Diseases of the Posterior EyePrincipal Investigator: margaret Deangelis, PhD

Genetic Analysis of Coats' Disease Patients and Correlation of Phenotypic and Imaging DataPrincipal Investigator: Mary Elizabeth Hartnett, MD

Post-approval Study of VisionCare's Implantable Miniature Telescope in Patients with End-stage Age-related Macular DegenerationPrincipal Investigator: majid moshirfar, mD, FacS

Efficacy of Pars Plana Vitrectomy and Subretinal Tissue Plasminogen Inhibitor for the Treatment of Submacular HemorrhagePrincipal Investigator: michael P teske, mD

Birdshot Chorioretinopathy OCT StudyPrincipal Investigator: albert t Vitale, mD

uVEITIS Multicenter Study of the Efficacy and Safety of the Human anti-TNF Monoclonal Antibody Adalimumab in Subjects with Inactive UveitisPrincipal Investigator: albert t Vitale, mD

Long-term Follow up of Patients Participating in the Multicenter Uveitis Steroid Treatment (MUST) TrialPrincipal Investigator: albert t Vitale, mD

Multicenter Study of the Long-term Safety and Efficacy of the Human anti-TNF Monoclonal Antibody Adalimumab in Subjects with Non-infectious UveitisPrincipal Investigator: albert t Vitale, mD

Multicenter Study of the Efficacy and Safety of the Human anti-TNF Monoclonal Antibody Adalimumab as Maintenance Therapy in Subjects Requiring High-dose Corticosteroids for Active UveitisPrincipal Investigator: albert t Vitale, mD

Utility of Lyme Antibody Testing in the Uveitis WorkupPrincipal Investigator: albert t Vitale, mD

Standardization of Uveitis Nomenclature Working GroupPrincipal Investigator: albert t Vitale, mD

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Balamurali K Ambati, MD, PhD, MBA7/25/13 Patent Filed/Secured: “The Schlemm's Stent-Sieve,” Balamurali Ambati, Alan S Crandall, Bruce Gale, christopher Lambert.

9/5/13 Patent L icensed/Exclusive: “Ocular Drug Delivery Using Lipids to Achieve Sustained Release,” Balamurali K Ambati, Michael Burr.

9/18/13 Patent Hold for More Data from Inventors: “COMP-Ang1 Mediated Retinal Neuronal Regeneration,” Balamurali K Ambati, Judd Cahoon.

Greg S Hageman, PhD4/9/13 Patent Published: “RCA Locus Analysis to Assess Susceptibility to AMD and MPGNII,” Australian patent application 2013203231.

4/12/13 Patent Granted: “Methods and Reagents for Treatment and Diagnosis of Vascular Disorders and Age-related Macular Degeneration,” Hong Kong patent 1168360.

6/14/13 Patent Granted: “Variants in Complement Regulatory Genes Predict Age-related Macular Degeneration,” Japanese patent 5290772.

6/25/13 Patent Granted: “Variants in Complement Regulatory Genes Predict Age-related Macular Degeneration,” Israeli patent 193396.

7/17/13 Patent Published: “Methods and Reagents for Treatment and Diagnosis of Vascular Disorders and Age-related Macular Degeneration,” US patent application 13/944,845.

7/30/13 Patent Granted: “Methods and Reagents for Treatment and Diagnosis of Vascular Disorders and Age-related Macular Degeneration,” Singapore patent 134720.

7/30/13 Patent Granted: “Therapeutic Compositions for Age-related Macular Degeneration Comprising a Complement Factor H with Isoleucine at Residue 62 and Tyrosine at Residue 402,” US patent 8,497,350 B2.

10/1/13 Patent Granted: “Methods and Reagents for Treatment and Diagnosis of Vascular Disorders and Age-related Macular Degeneration,” New Zealand patent application 595305.

10/5/13 Patent Granted: “Methods and Reagents for Treatment and Diagnosis of Vascular Disorders and Age-related Macular Degeneration,” Japanese patent 5100901.

12/10/13 Patent Allowed: “Protective Complement Proteins and Age-related Macular Degeneration,” Canadian patent application 2,638,759.

12/17/13 Patent Granted: “Methods and Reagents for Treatment and Diagnosis of Vascular Disorders and Age-related Macular Degeneration,” European patent application 12152177.7.

Bryan W Jones, PhD; Robert E Marc, PhD2012 – PresentPatent Pending: “Oncological Application of Computational Molecular Phenotyping.”

Technology Commercialization and Intellectual Property/Patents

J O H N A . M O R A N E y E C E N T E R

Patents, Patents Pending, Industry & Technology, Technological, and Other Scientific Innovations

2013-2014

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Bradley J Katz, MD, PhD9/27/13Patent Incorporated into another Tech: “Methods, Systems, and Apparatus for Reducing the Frequency and/or Severity of Photophobic Response,” Bradley J Katz, Steven Blair.

Founder and CEO of Axon Optics, www.axonoptics.com

Joined with Tecport Optics to develop a ground-breaking optical interference filter coating process for plastic spec-tacle lenses. The process blocks the specific wavelengths of light that have been implicated as the cause of photophobic symptoms, particularly those associated with triggering and exacerbating debilitating migraine headaches. The University of Utah has registered the existing proprietary property.

David Krizaj, PhD 2013 – Present Salcantay Vision Solutions, LLC, CEO. asha Vision, LLc, Founder and ceo. Entrepreneurial Faculty Scholars, University of Utah, member. Center for Translational Medicine, University of Utah, member.

3/14/12 – Present Patent Filed: “Compounds with TRPV4 Activity, Compositions and Associated Methods Thereof,” Priority date may 10, 2012.

5/10/12 – Present Patent Pending: “Role of TRPV4 Antagonists in Ocular Disease,” docket No. 00846-U5301, Krizaj D, Ryskamp DA, Barabas P. Inventor of a novel method for treatment of glaucoma and other ocular diseases associated with abnormal mechanical environment within the eye. The method has been validated in animal models and has the po-tential for a wide impact on clinical care, as they are currently no treatments that regulate intraocular pressure and protect retinal ganglion neurons in glaucoma.

10/16/12 – Present Patent Pending: “Mechanosensory Channel Antagonists in Glaucomatous Neuroprotection,” D Krizaj, P Barabas, y Xu, G Prestwich, Da ryskamp, 00846-US01. Priority date May 10, 2012.

Randall J Olson, MD7/7/2014 Patent Submitted: “A Safer Knife Blade.”

2012 – Present Patent Submitted: “A Vision Correction System to Minimize Intraocular Lens Rotation.”

Patent Pending: “A Vision Correction System,” patent 5087, International.

Patent Pending: “Hypodermic Needle System and Method to Reduce Infection,” patent 4826, International.

Barbara M Wirostko, MD10/24/13 Published: “Ocular Drug Delivery System,” PCT/US2013/036807, WO/2013/158661. An ocular drug delivery system including a composition in which a formulation having an active agent (e.g., HGH, rHGH or an HGH mimic) that increases insulin growth factor (IGF) or that alters insulin growth factor binding protein (IGFBP) in a subject is dispersed in a pharmaceutical carrier. The composi-tion is configured for placement in, around, or on an eye of the subject, and the composition provides controlled release of an amount of the active agent to the eye effective to promote ocular surface and corneal neural regeneration and wound healing.

2013 – present Patent Filed: “HGH for Ocular Diseases,” PCT/US serial no. is 61/956,070, provisional.

2012 – Present Patent Filed: “Corneal Reinnervation,” US submit-ted Patent No. 3246-005, provisional.

2011 – Present Patent Application Filed: “Corneal Wound Healing,” US Patent No. 61/62,4730.

2011 – Present Co-founder/ Chief Scientific Officer of Jade Therapeutics, Inc, Drug Development Company focusing on developing sustained delivery drugs and products via a novel propriety cross-linked hyaluronic acid polymer for ophthalmic areas of high unmet need. Recently received two Utah State Technol-ogy Commercialization and Innovation (TCIP) grants through USTAR, for $ 40,000 each, a Phase 1 NSF SBIR and a Phase 1 DOD SBIR grant.

J O H N A . M O R A N E y E C E N T E R

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January 16 Mary Elizabeth Hartnett, MD Insights into Recurrent Neovascularization Anti-VEGF Treatment in ROP

January 23 William Barlow, mD 1. Wound Burn & the Ultrachopper 2. Endophthalmitis Prophylaxis

January 30 Joseph L Hatch, MD Orson W White, MD, First Chairman, Division of ophthalmology, University of Utah

February 6 Russell Swan, MD, Intern Future Advancements in Refractive Surgery

Kevin Meier, MD, Neurology Resident, A Patient with Alternating Skew Deviation & University of Utah Down-beat nystagmus

February 13 Nikko Ronquillo, Graduate Research Assistant Senior-Loken Syndrome: From Human Genetics to an animal model

Beatrice Des Marchais, MD, Transconjunctival Sutures: When, Why, How? Quebec city, Quebec

February 20 Margaret DeAngelis, PhD Identifying Pathways Using Genetic Risk Factors & Their Modifiers to Develop Appropriate Targets for Therapies & Prevention of Age-related Macular Degeneration

February 27 Alan S Crandall, MD From Bench to Practice

March 6 Roger P Harrie, MD The Friday-at-5:00pm-Patient

March 13 Jason Edmonds, MD Amantadine Induced Corneal Endothelial Toxicity

March 20 Adam Gess, MD A Patient with Fungal Keratitis

March 27 Ore-Ofe Adesina, MD What I've Been Up To

April 10 Randall J Olson, MD; Alan S Crandall, MD; Health Care Policy & Affordable Care Act Jeff Pettey; MD, and Wayne Imbrescia

April 17 Ronald Hobbs, MD, Retina Fellow What to Present, It Is So Hard to Pic

April 24 Akbar Shakoor, MD, Retina Fellow Diagnostic Challenges in Sarcoidosis

Ligia Viorela Onofrei, MD, Neurology Resident, Ophthalmic Manifestations of NF-1 University of Utah

may 1 charles Weber, mD, cornea Fellow oct in the assessment of Glaucoma

Rachel Epstein, MSIV, Chicago Medical School Rapidly Progressive Proptosis in a Child

May 22 Derek Holt, MD, PhD, Chief Resident Neuroplasticity & Amblyopia

Kevin Kirk, MSII, University of Utah Pathology of 1-Piece & 3-Piece Intraocular Lenses Fixated in the Ciliary Sulcus

May 29 Caleb Morris, MSIII, Duke University Case Report on Fulminant Intracranial (Research with Mamalis/Werner Lab) Hypertension

June 12 Zachary Joos, MD, Intern You'll Shoot Your Eye Out!: BB Gun Injuries & Intraocular Foreign Bodies

June 19 Adam Jorgensen, MD, Intern Lateral rectus mass in a 67-year-old male

Derek Holt, MD, Chief Resident 18-Year-Old Patient with Optic-neuropathy

July 17 Christine Lippe, MSIV, Penn State Bilateral acute angle closure Glaucoma due to oral acetazolamide

Ryan Constantine, MSIV, University of Utah UNC119 is Required for G-Protein Trafficking in Sensory neurons

Max Padilla, MSIV, University of Utah Intralase-Astigmatic Keratotomy Concurrent with Phacoemulsification

Lauren Imbornoni, MSIV, University of Arizona COM A Case Report of Recurrent Epithelial Irregularity

July 31 Lori Myers, MSIV, Indiana University SOM July & the OPEN GLOBE: To Wait, Eviscerate, or enucleate?

David Sanders, MSIV, Oregon Health and Science electronic Health record Systems in ophthal- mology: Ophthalmology: Impact on Clinical Documentation

D A T E P R E S E N T E R T O P I C O R T I T L E

2013Grand Rounds

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August 7 Dane Stewart, MSIV, Virginia Infrared Imaging as a Tool to Detect Glaucomatous Commonwealth University Changes of the Optic Nerve

Ashlie Bernhisel, MSIV, University of Utah, Neuronal Regeneration Neuro-Ophthalmology

Tina Burton, MD, Neurology Resident A Case of Optic Neuropathy in a Patient with Atrial Fibrillation

August 14 Devin West, MSIV, St. Louis University SOM CPEO: A Family Affair

Erik Ostler, MSIV, University of Utah Statistical Methods of Ophthalmology: Unlocking the Black Box

Paul Selid, MSIV, University of North Dakota Avastin vs Eylea in Exudative ARMD: More than Anecdotal Evidence

August 21 Ryan Hoggan, MSIV, University of Utah Angle Kappa & Its Importance in Refractive Surgery

Kam Hanamaikai, MSIV, A.T. Still University SOM-AZ corneal cross-Linking

P James Tucker, MSIV, University of Utah Retinal Geography: Evolutionary Specialization & Differential Disease Susceptibility

August 28 Randall J Olson, MD What Resulteth from a Minor Tip Change

Elizabeth Doll, MD, Neurology Resident, Ocular Manifestations of Bariatric Surgery University of Utah Pediatrics

September 4 Ana Kesler, MD, Sackler SOM, ophthalmology, Pseudotumor cerebri Tel Aviv Medical Center, Israel, neuro-ophthalmology

September 11 Joshua Ford, MD, Pathology Fellow, Light Adjustable Lens & Other Intraocular Power University of Utah SOM adjustable technologies

September 18 Tyson Olson, MSIV, University of Rochester, SOM Orbitalfacial Neurofibromatosis & Vision Loss

Aabid Farukhi, MSIV, University of Utah Does Phaco Tip Diameter Impact Efficiency & Chatter

September 25 Kevin Kirk, MSIV, University of Utah Uveitis Nomenclature

Sean Hansen, MSIV, Medical College of Wisconsin assessing Photoreceptor Structure Following macular Hole closure

Matt Miller, MSIV, University of Utah Pseudotumor cerebri Secondary to tetracycline Antibiotics

October 2 Eileen Hwang, MD, PhD, Intern Do Patients with Hollenhorst Plaques Really Need Carotid Ultrasounds & Echocardiograms?

Ashlie Bernhisel, MSIV, University of Utah, Ocular Manifestations of Plaquenil Toxicity neuro-ophthalmology

October 16 R Michael Duffin, MD, and Mark D Mifflin, MD Bolivia 2013: Second Cornea Transplant Campaign

October 23 Nick Mamalis, MD Binkhorst IOLS

October 30 Jim Bell, MD, Intern A Bump in the Iris

November 6 Balamurali K Ambati, MD, PhD, MBA Front & Back: Clinical Course & Retina Research

November 13 Dan Bettis, MD, Intern Seven-Year-Old with Recurrent Exotropi

Faiz rehmani, mD, neurology resident, Homonymous Hemianopia University of Utah

November 20 Leah Owen, MD, PhD, Intern NAION in a Patient with Posner-Syndrome

International Outreach to the Navajo Reservation

December 4 Alan S Crandall, MD New Cataract Surgical Techniques

December 11 Barbara M Wirostko, MD Pseudoexfoliation: What is Known and What is new

D A T E P R E S E N T E R T O P I C O R T I T L E

Grand Rounds 2013

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A sample of more than 200 published and presented materials by Moran faculty members between January 1 and December 31, 2013

P u B L I S H E D R E S E A R C H

ACS NanoLuo L, Zhang X, Hirano y, tyagi P, Barabas P, Uehara H, Miya TR, Singh N, Archer B, Qazi Y, Jackman K, Das SK, olsen t, chennamaneni Sr, Stagg BC, ahmed F, emerson L, Zygmunt K, Whi-taker R, Mamalis C, Huang W, Gao G, Srinivas SP, Krizaj D, Baffi J, Ambati J, Kompella UB, Ambati BK. Targeted intraceptor nanoparticle therapy reduces angiogenesis and fibrosis in primate and murine macular degeneration. ACS Nano. 2013; 7(4), 3264-75

American Journal of Medical GeneticsTantravahi SK, Williams LB, Digre KB, Creel DJ, Smock KJ, DeAngelis M, clayton Fc, Vitale AT, rogers Gm. An inherited disorder with splenomegaly, cytopenias, and vision loss. Am J Med Genet. 2013; 158A(3):475-81

American Journal of Ophthalmology Uchino M, Yokoi N, Uchino Y, Dogru M, Kawashima m, Komuro a, Sonomura y, Kato H, Kinoshita S, Schaumberg DA, tsubota K. Prevalence of dry eye disease and its risk factors in visual display terminal users: The osaka study. Am J Ophthalmol. 2013 Oct;156(4):759-66

American Journal of Pathology Wang H, Smith GW, yang Z, Jiang y, mccloskey m, Greenberg K, Geisen P, culp WD, Flannery J, Kafri t, Hammond S, Hartnett ME. Short hairpin RNA-mediated knockdown of VEGFA in muller cells reduces intravitreal neovascularization in a rat model of retinopathy of prematurity. Am J Pathol. 2013 Aug;183(3):964-74

Archives of Biochemistry and Biophysics Vachali PP, Besch Bm, Gonzalez-Fernandez F, Bernstein PS. Carotenoids as possible interphotoreceptor retinoid-binding protein (IRBP) ligands: A surface plasmon resonance (SPR) based study. Arch Biochem Biophys. 2013 Nov;539(2):181-6

Archives of OphthalmologyShelton JB, Digre KB, Gilman J, Warner JE, Katz BJ. Characteristics of myelinated retinal nerve fiber layer in ophthalmic imaging: Findings on autofluorescence, fluorescein angiographic, infrared, optical coherence tomographic, and red-free images. Arch Ophthalmol. 2013; 0(0), 1-3

BMC Neuroscience Green Ja, yang J, Grati M, Kachar B, Bhat MA. Whirlin, a cytoskeletal scaffolding protein, stabilizes the paranodal region and axonal cytoskeleton in myelinated axons. BMC Neurosci. 2013; 14, 96

BloodSingh n, tiem m, Watkins r, cho yK, Wang y, Olsen T, Uehara H, Mamalis C, Luo L, Oakey Z, Ambati BK. Soluble vascular endothelial growth factor receptor 3 is essential for corneal alymphaticity. Blood. 2013 May;121(20):4242-9

British Journal of Nutrition Scarmo S, Cartmel B, Lin H, Leffell DJ, Ermakov IV, Gellermann W, Bernstein PS, mayne St. Single v. multiple measures of skin carotenoids by resonance raman spectroscopy as a biomarker of usual carotenoid status. Br J Nutr. 2013 Jan;28:1-7

Case Reports in Ophthalmological MedicineGupta I, Oakey Z, Stagg BC, Ambati BK. Minus piggyback lens overlaying ReSTORE multifocal lens in high myopia. Case Reports in Ophthalmological Medicine. 2013; 4(2), 57-60

Cataract & Refractive Surgery TodayAmbati BK, Auffarth GU, Hardten DR, Koch DD, carlson an. How to manage PCO in an aphakic eye. Cataract & Refractive Surgery Today. 2013; 13(3), 22-24

Cell Death and Diseasesma e, Lewis a, Barabas P, Stearns G, Suzuki S, Krizaj D, Brockerhoff SE. Loss of Pde6 reduces cell body Ca2+ transients within photoreceptors. cell Death Dis. 2013 Sep;4:e797

Cerebral CortexJeffs J, Federer F, Ichida JM, Angelucci A. High-resolution mapping of anatomical connections in marmoset extrastriate cortex reveals a complete representation of the visual field bordering dorsal V2. Cereb Cortex. 2013 May;23(5):1126-47

Clinical Obstetrics and Gynecology Digre KB. Headaches during pregnancy. Clin Obstet Gynecol. 2013 Jun;56(2):317-29

Digre KB, Verner m. Neurological diseases in pregnancy: An overview. Clin Obstet Gynecol. 2013 Jun;56(2):303-4

Computercook DJ, Crandall AS, thomas BL, Krishnan nc. CASAS: A Smart Home in a Box. Computer. 2013; 46(7)

CorneaKim HK, Choi JA, Uehara H, Zhang X, Ambati BK, cho yK. Presurgical corticosteroid treatment improves corneal transplant survival in mice. Cornea. 2013; 32(12), 1591-8

Moshirfar M, et al. In vitro pilot analysis of uniformity, circularity, and concentricity of DSAEK donor endothelial grafs prepared by a microkeratome. Cornea. 2013; (12)

Moshirfar M, Jarstad a, Khalifa ym. Descemet membrane endothelial keratoplasty: Why does the donor tissue roll? Cornea. 2013; 32(4), e52-3

Feiz V, nijm L, Glickman rD, morse LW, Telander DG, Park SS, Polage CR, Christiansen Sm, Moshirfar M. Vitreous and aqueous penetration of orally administered trimethoprim-sulfamethoxazole combination in humans. Cornea. 2013 Oct;32(10):1315-20

Hsu m, Jorgensen aJ, Moshirfar M, Mifflin MD. Management and outcomes of descemet stripping automated endothelial keratoplasty with intraocular lens exchange, aphakia, and anterior chamber intraocular lens. Cornea. 2013 May;32(5):e64-8

Kim G, Singleton r, Mifflin MD, Digre KB, Porzio mt, Smith aG. Assessing the reproducibility of quantitative in vivo confocal microscopy of corneal nerves in different corneal locations. Cornea. 2013 Oct;32(10):1331-8

Current Diabetes ReportsHartnett ME, Owen L. Soluble mediatros or diabetic macular edema: The diagnostic role of aqueous VEGF and cytokine levels in diabetic macular edema. Curr Diab Rep. 2013; 13(4), 476-80

Current Ophthalmology Reports Moshirfar M. LASIK and surface ablation in the modern era: Trends and novel applications. Curr Ophthalmology rep. 2013

Uchino M, Schaumberg DA. Dry eye disease: Impact on quality of life and vision. Curr Oph-thalmol Rep. 2013 Jun;1(2):51-7

Development Pollak J, Wilken MS, Ueki Y, Cox KE, Sullivan JM, taylor rJ, Levine EM, reh ta. ASCL1 reprograms mouse muller glia into neurogenic retinal pro-genitors. Development. 2013 Apr;140(12): 2619-31

eLife Luo L, Uehara H, Zhang X, Das SK, Olsen T, Holt D, Simonis Jm, Jackman K, Singh n, miya tr, Huang W, Ahmed F, Bastos-Carvalho A, Le YZ, Mamalis C, Chiodo VA, Hauswirth WW, Baffi J, Lacal Pm, orecchia a, Ferrara n, Gao G, young-Hee K, Fu y, Owen L, albuquerque r, Baehr W, Thomas K, Li DY, Chalam KV, Shibuya M, Grisanti S, Wilson DJ, Ambati J, Ambati BK. Photorecep-tor avascular privilege is shielded by soluble VEGF receptor-1. eLife. 2013; 2, e00324

Experimental Eye Research cahoon Jm, olson Pr, nielson S, miya tr, Bankhead P, McGeown JG, Curtis TM, Ambati BK. Acridine orange leukocyte fluorography in mice. Exp Eye Res. 2013; 120C, 15-19

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Eye Contact Lens Adesina OO, Vickery JA, Ferguson CL, Stone DU. Stromal melting associated with a cosmetic contact lens over a Boston keratoprosthesis: Treatment with a conjunctival flap. Eye Contact Lens. 2013; 39(3), e4-6

EyeWorldDaly r, Moshirfar M. Expanding options for phakic lenses. EyeWorld. 2013; (10), 1-2

The FASEB JournalUehara H, Cho Y, Simonis J, Cahoon J, Archer B, Luo L, Das SK, Singh N, Ambati J, Ambati BK. Dual suppression of hemangiogenesis and lymphangiogenesis by splice-shifting morpholinos targeting vascular endothelial growth factor receptor 2 (KDR). FASEB J. 2013; 27(1), 76-85

Wang H, Jiang y, Shi D, Quilliam La, Chrzanowska-Wodnicka M, Wittchen ES, Li Dy, Hartnett ME. Activation of Rap1 inhibits NADPOH oxidase-dependent ROS generation in retinal pigment epithelium and reduces choroidal neovascularization. FASEB J. 2013

HeadacheFriedman DI, Digre KB. Headache medicine meets neuro-ophthalmology: Exam techniques and challenging cases. Headache. 2013 Apr;53(4):703-16

Human Gene TherapyBoye SL, Peshenko IV, Huang WC, Min SH, McDoom I, Kay CN, Liu X, Dyka FM, Foster TC, Umino Y, Karan S, Jacobson SG, Baehr W, Dizhoor a, Hauswirth WW, Boye Se. AAV-mediated gene therapy in the guanylate cyclase (RetGC1/RetGC2) double knockout mouse model of Leber Congenital Amaurosis. Human Gene Therapy. 2013 Feb;24(2):189-202

Human Molecular GeneticsZou J, Zheng t, ren c, askew c, Liu X, Pan B, Holt Jr, Wang y, yang J (In press). Deletion of PDZD7 disrupts the usher syndrome type 2 protein complex in cochlear hair cells and causes hearing loss in mice. Hum Mol Genet. 2013

Image Processing, IEEE TransactionsJagadeesh V, manjunath BS, anderson J, Jones BW, Marc R, Fisher SK. Robust segmentation based tracing using an adaptive wrapper for inducing priors. Image Proc, IEEE Trans. 2013 Dec;22(12):4952-63

International Journal of Environmental Research and Public HealthWest SK, Bates mn, Lee JS, Schaumberg DA, Lee DJ, adair-rohani H, chen DF, araj H. Is household air pollution a risk factor for eye disease? Int J Environ Res Public Health. 2013; 10(11), 5378-98

International Ophthalmology ClinicsShakoor A, Vitale AT. Imaging in the diagnosis and management of multifocal choroiditis and punctate inner choroidopathy. Inter Ophth Clinic. 2013; 52(54):243-56

Investigative Ophthalmology and Visual Sciences mccloskey m, Wang H, Jiang y, Smith GW, Strange J, Hartnett ME. Anti-VEGF antibody leads to later atypical intravitreous neovascularization and activation of angiogenic pathways in a rat model of ROP. Invest Ophthalmol Vis Sci. 2013; 54(3), 2020-6

Bernstein PS, Sharifzadeh M, Liu A, Ermakov I, Nelson K, Sheng X, Panish C, Carlstrom B, Hoffman RO, Gellermann W. Blue-light reflectance imaging of macular pigment in infants and children. Invest Ophthalmol Vis Sci. 2013; 54(6), 4034-40

meyers KJ, Johnson eJ, Bernstein PS, Iyengar SK, Engelman CD, Karki CK, Liu Z, Igo RP Jr, Truitt B, Klein mL, Snodderly Dm, Blodi Ba, Gehrs Km, Sarto Ge, Wallace rB, robinson J, LeBlanc eS, Hageman G, tinker L, mares Ja. Genetic determinants of macular pigments in women of the carotenoids in Age-Related Eye Disease Study. Invest Ophthalmol Vis Sci. 2013; 54(3), 2333-45

Nichols JJ, Willcox MD, Bron AJ, Belmonte c, ciolino JB, craig JP, Dogru m, Foulks Gn, Jones L, nelson JD, nichols KK, Purslow c, Schaumberg DA, Stapleton F, Sullivan DA. The TFOS International Workshop on Contact Lens Discomfort: Executive Summary. Invest Ophthalmol Vis Sci. 2013; 54(11), TFOS7-TFOS13

amparo F, Sadrai Z, Jin y, alfonso-Bartolozzi B, Wang H, Shikari H, ciolino JB, chodosh J, Jurkunas U, Schaumberg DA, Dana r. Safety and efficacy of the multitargeted receptor kinase inhibitor pazopanib in the treatment of corneal neovascularization. Invest Ophthalmol Vis Sci. 2013; 54(1), 537-44

Foulks G, chalmers r, Keir n, Woods ca, Simpson t, Lippman r, Gleason W, Schaumberg DA, Willcox MDP, Jalbert I, Members of the TFOS International Workshop on Contact Lens Discomfort. The TFOS international workshop on contact lens discomfort: Report of the subcommittee on clinical trial design and outcomes. Invest Ophthalmol Vis Sci. 2013 Oct;54(11):TFOS157

Henriksen BS, chan G, Hoffman RO, Sharifzadeh M, Ermakov IV, Gellermann W, Bernstein PS. Interrelationships between maternal and carotenoid status and newborn infant mauclar pigment optical density and carotenoid status. Invest Ophthalmol Vis Sci. 2013 Aug;54(8): 5568-78

Ambati BK. A new target for simultaneous inhibition of hem- and lymphangiogensis. Invest Ophthalmol Vis Sci. 2013; 54(6), 6

Journal of AAPOSHartnett ME, Lane r. Effects of oxygen on the development and severity of retinopathy of prematurity. J AAPOS. 2013; 17(3), 229-34

Kleinmann G, Zaugg B, apple DJ, Bleik J. Pediatric cataract surgery with hydrophilic acrylic intraocular lens. J AAPOS. 2103 Aug;17(4):367-70

JAMA age-related eye Disease Study 2 research Group (06/18/2013). Bernstein PS. Lutein + zeaxanthin and omega-3 fatty acids for age-related macular degeneration: The Age-Related Eye Disease Study 2 (AREDS2) randomized clinical trial. JAMA, 309 (may 15, 2013), 2005-2015

JAMA Ophthalmologyahmed F, Kamae KK, Jones DJ, DeAngelis MM, Hageman GS, Gregory mc, Bernstein PS. Temporal macular thinning associated with x-linked alport syndrome. JAMA Ophthalmol. 2013; 131(6), 777-82

Wang H, Zhang SX, Hartnett ME. Signaling pathways triggered by oxidative stress that mediate features of severe retinopathy of prematurity. JAMA Ophthalmol. 2013; 131(1), 80-5

Zhang a, Moshirfar M, Khalifa ym. Deep vein thrombosis following descemet stripping automated endothelial keratoplasty. JAMA Ophthalmol. 2013; 13(9), 1233-4

amparo F, Dastjerdi mH, okanobo a, Ferrari G, Smaga L, Hamrah P, Jurkunas U, Schaumberg DA, Dana r. Topical interleukin 1 receptor antagonist for treatment of dry eye disease: A randomized clinical trial. JAMA Ophthalmol. 2013; 131(6), 715-23

Mitta VP, Christen WG, Glynn RJ, Semba RD, ridker Pm, rimm eB, Hankinson Se, Schaumberg DA. C-reactive protein and the incidence of macular degeneration: Pooled analysis of 5 cohorts. JAMA Ophthalmol. 2013; 131(4), 507-13

muni rH, Kohly rP, Lee eQ, manson Je, Semba rD, Schaumberg DA. Prospective study of inflammatory biomarkers and risk of diabetic retinopathy in the diabetes control and complications trial. JAMA Ophthalmol. 2013; 131(4), 514-21

Shelton J, Digre KB, Gilman J, Warner JE, Katz BJ. Characteristics of myelinated retinal nerve fiber layer in ophthalmic imaging: Findings on autofluorescence, florescein angiographic, infrared, optical coherence tomographic, and red-free images. JAMA Ophthalmol. 2013; 131(1), 107-9

Journal of Biological Chemistryyang Z, tsuchiya H, Zhang y, Hartnett ME, Wang L. MicroRNA-433 inhibits liver cancer cell migration by repressing the protein expression and function of cAMP response element-binding protein. J Biol Chem. 2013; 288(40), 28893-9

Journal of Biomedical OpticsSharifzadeh m, Bernstein PS, Gellermann W. Reflection-based imaging of macular pigment distributions in infants and children. J Biomed Opt. 2013; 18(11), 116001

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Journal of Clinical Neuroscience Dersu II, Thostenson J, Durcan FJ, Hamilton SM, Digre KB. Optic disc and visual test findings in patients with migraine. J Clin Neurosci. 2013 Jan;20(1):72-4

Journal of Comparative NeurologyLaurizten JS, anderson Jr, Jones BW, Watt CB, mohammad S, Hoang JV, Marc RE. On cone bipolar cell axonal synapses in the off inner plexiform layer of the rabbit retina. J Comp Neurol. 2013 Apr;521(5):977-1000

Journal of Controlled Releasechennamaneni Sr, mamalis c, archer B, oakey Z, Ambati BK. Development of a novel bioerodible dexamethasone implant for uveitis and postoperative cataract inflammation. J Control Release. 2013; 167(1), 53-9

Journal of Glaucoma maeda-chubachi t, chi-Burris K, Simons B, Bremond-Gignac D, Freedman S, Khaw Pt, Wirostko B, yan e, a6111137 Study Group. Impact of age, diagnosis, and history of glaucoma surgery on outcomes in pediatric patients treated with latanoprost. J Glaucoma. 2013 Oct/Nov;22(8):614-19

Journal of Neuro-Ophthalmology Katz BJ, Crum AV, Digre KB, Warner JE. Optic disc edema and optic nerve head drusen. J Neuroophthalmol. 2103; 33(2), 204-5

Keung Bm, Shah Lm, eckart De, Digre KB, chin SS, Warner JE. A mystery case of proptosis, optic neuropathy, and peripheral neuropathy, clinical-pathological case study. J Neuroophthalmol. 2013 Jan;2013(33), 77-82

The Journal of Neuroscience Lai CW, Kolesnikov AV, Frederick JM, Blake Dr, Jiang L, Stewart JS, chen cK, Barrow Jr, Baehr W, Kefalov VJ, Willardson BM. Phosducin-like protein 1 is essential for G-Protein assembly and signaling in retinal rod photoreceptors. J Neurosci. 2013; 33(18), 7941-7951

Federer F, Williams D, Ichida JM, Merlin S, Angelucci A. Two projection streams from macaque V1 to the pale cytochrome oxidase stripes of V2. J Neurosci. 2013 Jul;33(28):11530-9

Gordon PJ, yun S, clark am, monuki eS, murtaugh c, Levine EM. Lhx2 balances progenitor maintenance with neurogenic output and promotes competence state progression in the developing retina. J Neurosci. 2013 Jul;33(30):12197-207

Shushruth S, Nurminen L, Bijanzadeh M, Ichida Jm, Vanni S, Angelucci A. Different orientation tuning of near- and far-surround suppression in macaque primary visual cortex mirrors their tuning in human perception. J Neurosci. 2013 Jan;33(1):106-19

Xu J, morris L, thapa a, ma H, michalakis S, Biel m, Baehr W, Peshenko IV, Dizhoor AM, Ding X-Q. cGMP accumulation causes photoreceptor degeneration in CNG channel deficiency: Evidence of xGMP cytotoxicity independently of enhanced cng channel function. J Neurosci. 2013 Sep;33(37):14939-48

Journal of Cataract and Refractive SurgeryFloyd am, Werner L, Liu e, Stallings S, ollerton a, Leishman L, Bodnar Z, morris c, Mamalis N. Capsular bag opacification with a new accommodating intraocular lens. J Cataract Refract Surg. 2013; 39, 1415-1420

Moshirfar M. Corneal surgical problem: October consultation #1. J Cataract Refract Surg. 2013; 39(10), 1618-20

Moshirfar M. Refractive surgical problem: April consultation #1. J Cataract Refract Surg. 2013; 39(4), 652-4

Moshirfar M, Edmonds JN. March consultation #8. J Cataract Refract Surg. 2013; 39(3), 479

assia e, Bellucci r, el Danasoury a, Snyder me, cochener B, Kohnen t, Moshirfar M, Edmonds JN, Guell JL. Refractive surgical question: March consultation. J Cataract Refract Surg. 2013; 39(3), 475-80

oakey ZB, Jensen JD, Zaugg BE, radmall Br, Pettey JH, Olson RJ. Porcine lens nuclei as a model for comparison of 3 ultrasound modalitites regarding efficiency and chatter. J Cataract Refract Surg. 2013; 39(8), 1248-53

osher rH, Tabin GC, nagy ZZ, Crandall AS, agarwal a, Jacob S, chang DF, Koch DD, Fishkind WJ, Chakrabarti A. Cataract surgical problem: February consultation. J Cataract Refract Surg. 2013; 39(2), 299-304

Fellman ma, Werner L, Liu et, Stallings S, Floyd AM, van der Meulen IJE, Lapid-Gortzak R, nieuwendaal cP. Calcification of a hydrophilic acrylic intraocular lens after descemet-stripping endothelial keratoplasty: Case report and laboratory analyses. J Cataract Refract Surg. 2013 May;39(5):799-803

Jorge PDa, Jorge D, Ventura cV, Ventura BV, Lira W, Ventura mc, Werner L, Kara-Junior n. Late opacification in hydrophilic acrylic intraocular lenses: Analysis of 87 eyes in a random sample of 102 patients. J Cataract Refract Surg. 2013 Mar;39(3):403-7

Kinard K, Jarstad a, Olson RJ. Correlation of visual quality with satisfaction and function in a normal cohort of pseudophakic patients. J Cataract Refract Surg. 2013 Apr;39(4):590-7

richman J, Spaeth GL, Wirostko B. Contrast sensitivity basics and a critique of currently available tests. J Cataract Refract Surg. 2013 Jul;39(7):1100-6

Journal of Cell Science Avasthi P, Scheel JF, Ying G, Frederick JM, Baehr W, Wolfrum U. Germline deletion of Centn1 causes infertility in male mice. J Cell Sci. 2013 Apr;126(14):3204-13

Journal of Chromatography ALiu a, terry r, Lin y, nelson K, Bernstein PS. Comprehensive and sensitive quantification of long-chain and very long-chain polyunsaturated fatty acids in small samples of human and mouse retina. J Chromatogr A. 2013; 1307, 191-200

Journal of Ocular Pharmacology and Therapeutics Pettey JH, Mifflin MD, Kamae K, McEntire MW, Pettey DH, Callegan MC, Brown H, Olson RJ. The impact of short-term topical gatifloxacin and moxifloxacin on bacterial injection after hypodermic needle passage through human conjunctiva. J Ocul Pharmacol Ther. 2013; 29(5), 450-455

Molokhia SA, Thomas SC, Garff KJ, Mandell KJ, Wirostko BM. Anterior eye segment drug delivery systems: Current treatments and future challenges. J Ocul Pharmacol Ther. 2013 Mar;29(2):92-105

Journal of Pediatric Gastroenterology and Nutritionchan Gm, chan mm, Gellermann W, Ermakov I, Ermakova M, Bhosale P, Bernstein PS, rau c. Resonance Raman spectroscopy and the preterm infant carotenoid status. J Pediatr Gastroenterol Nutr. 2013; 56(5), 556-9

Journal of the Peripheral Nerve SystemSmith aG, Kim G, Porzio m, allen B, Koach m, Mifflin MD, Digre KB, Keung Bm, Singleton Jr. Corneal confocal microscopy is efficient, well-tolerated, and reproducible. J Peripher Nerv Syst. 2013; 2013(18), 54-58

Journal of Refractive SurgeryMoshirfar M, Simpson RG, Dave SB, Christiansen SM, Edmonds JN, culbertson WW, Pascucci SE, Sher NA, Cano DB, Trattler WB. Sources of medical error in refractive surgery. J Refract Surg. 2013; 29(5), 303-10

Nature Genetics Hageman GS, The AMD Gene Consortium. Seven new loci associated with age-related macular degeneration. Nat Genet. 2013

Helgason H,…Bernstein PS, et al,. A rare nonsynonymous sequence variant in C3 is associated with high risk of age-related macular degeneration. Nat Genet. 2013; 45(11), 1371-4

Fritsche LG,… Schaumberg DA, Hageman GS, DeAngelis MM,…abecasis Gr. et al., Seven new loci associated with age-related macular degeneration. Nat Genet. 2013; 45(4), 433-9, 439e1-2

Nepalese Journal of Ophthalmology thapa r, Poudyal G, Crandall AS, Tabin G. Vitreo-retinal disorders at high altitude in Nepal. Nepal J Ophthalmol. 2013; 5(9), 57-62

Neuffer MC, Khalifa YM, Moshirfar M, Mifflin MD. Prospective comparison of chilled versus room temperature saline irrigation in alcohol-assisted photorefractive keratectomy. Nepal J Ophthalmol. 2013; 5(2), 154-160

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The New England Journal of Medicine Hartnett ME, Penn JS. Mechanisms and management of retinopathy of prematurity. N Engl J Med. 2013; 368(12), 1162-3

Ocular Immunology and InflammationOberg TJ, Vitale AT, Hoffman RO, Bohnsack JF, Warner JE. Cryopyrin-associated periodic syndromes and the eye. Ocul Immunol Inflamm. 2013

Morshedi RG, Bettis DI, Moshirfar M, Vitale AT. Bilateral acute iris transillumination following systemic moxifloxacin for respiratory illness: Report of two cases and review of the literature. Ocul Immunol Inflamm. 2013; 20(4):266-72

Vitale AT, Graham e, de Boer JH. Juvenile idiopathic arthritis-associated uveitis: Clinical features and complications, risk factors for severe course, and visual outcomes. Ocul Immunol Inflamm. 2013; 21(6):478-85

Ocular Surgery News (US Edition) Crandall AS. Improving efficiency with advances in phacoemulsification technology. Ocular Surgery News (US Edition). 2013; (08), 10

Oman Journal of Ophthalmology Moshirfar M, et al. Angle Kappa and its importance in refractive surgery. Oman J Ophthalmol. 2013; 6(3), 151-58

Moshirfar M, Edmonds JN, Behunin nL, Christiansen SM. Corneal biomechanics in latrogenic ectasia and keratoconus: A review of the literature. Oman J Ophthalmol. 2013; 6(1), 12-17

Ophthalmic Research Demill DL, Wirostko BM, nelson La, Stewart Ja, Steart Wc. Average versus highest intraocular pressure analyses in glaucoma clinical trials. Ophthalmic Res. 2013 Oct;49:49-5

Ophthalmology Perlee Lt, Bansal at, Gehrs K, Heier JS, csaky K, allikmets r, oeth P, Paladino t, Farkas DH, rawlings PL, Hageman GS. Inclusion of genotype with fundus phenotype improves accuracy of predicting choroidal neovascularization and geographic atrophy. Ophthalmology. 2013

ollerton a, Werner L, Strenk S, Strenk L, Leishman L, Bodnar Z, Kirk Kr, michelson J, Mamalis N. Pathologic comparison of asymmetric or sulcus fixation of 3-piece intraocular lenses with square versus round anterior optic edges. Ophthalmology. 2013; 120(8), 1580-7

Moshirfar M. Sun damage: Darker not better for sunglasses. Ophthalmology. 2013; (7), 11-13

PLoS ONE Schaumberg DA, Uchino M, Christen WG, Semba rD, Buring Je, Li JZ. Patient reported differences in dry eye disease between men and women: Impact, management, and patient satisfaction. PLoS ONE. 2013; 8(9), e76121

Wittchen ES, Nishimura E, McCloskey M, Wang H, Quilliam La, chrzanowska-Wodnicka m, Hartnett ME. Rap1 GTPase activation and barrier enhancement in RPE inhibits choroidal neovascularization in vivo. PLoS ONE. 2013 Sep;8(9), e73070

Heynen SR, Meneau I, Caprara C, Samardzija M, Imsand C, Levine EM, Grimm c. CDC42 is required for tissue lamination and cell survival in the mouse retina. PLoS One. 2013 Jan;8(1):e53806

Jiang L, Li tZ, Boye Se, Hauswirth WW, Frederick JM, Baehr W. RNAi-mediated gene suppression in a GCAP1(L151F) cone-rod dystrophy mouse model. PLoS One. 2013 Mar;8(3):e57676

Woodell a, coughlin B, Kunchithapautham K, casey S, Williamson t, Ferrell WD, atkinson c, Jones BW, rohrer B. Alternative complement pathway deficiency ameliorates chronic smoke-induced functional and morphological ocular injury. PLoS One. 2013 Jun;8(6):e67894

Proceedings of the National Academy of Sciences of the United States of America Barabas P, Liu A, Xing W, Chen CK, Tong Z, Watt cB, Jones BW, Bernstein PS, Krizaj D. Role of ELOVL4 and very long-chain polyunsaturated fatty acids in mouse models of Stargardt type 3 retinal degeneration. Proc Natl Acad Sci U S A. 2013; 110(13), 5181-6

Proceedings of the Royal Society B rosa mGP, Angelucci A, Jeffs J, Pettigrew JD. The case for a dorsomedial area in the primate 'third tier' visual cortex. Proc Roy Soc B. 2013 Apr;280:20121372

Progress in Retinal and Eye Research Marc RE, Jones BW, Watt CB, Anderson JR, Sigulinsky c, Lauritzen S. Retinal connectomics: Towards complete, accurate networks. Prog Retin Eye Res. 2013; 37:141-62

Retina Blair mP, Shapiro mJ, Hartnett ME. Peripheral retinal nonperfusion in fellows eyes in Coats’ Disease. Retina. 2013

Xu L, Blonska am, Pumariega nm, Bearelly S, Sohrab ma, Hageman GS, Smith rt. Reticular macular disease is associated with multilobular geographic atrophy in age-related macular degeneration. Retina. 2013 Oct;33(9):1850-62

Review of Ophthalmology Bethke W, Moshirfar M. The dos and don’ts of phakic lens implants. Rev Ophth. 2013; (11), 1-3

Book Chapters PublishedAlan S Crandall Complications in Glaucoma Surgery. In Agarwal A, Jacob S (Eds.), Complications in Ocular Surgery (2013, one, pp. 159-63). Thorofare, NJ: SLACK Incorporated. Glaucoma. In Amar Agarwal (Ed.), Handbook of Ophthalmology (10, pp. 325-359). Thorofare, NJ: SLACK Incorporated. Sidebar: ultra Chopper Theory and Technique. In David F. Chang (Ed.), Phaco Chop and Advanced Phaco Techniques. Strategies for Complicated Cataracts (Second, p. 114). Thorofare, NJ: SLACK Incorporated.

Rachael S Jacoby Vitale AT, Kump LI, Jacoby RS (2013). Pregnancy and uveitis. In Foster SC, Vitale AT (Eds.), Diagnosis and Treatment of Uveitis (2nd, pp. 1254-62). New Dehli: Jaypee-Highlights Medical Publishers, Inc.

Nick Mamalis nagi KS, Khaimi ma, Mamalis N (2013). Early Excessive Iritis. In Feldman RM, Bell NP (Eds.), Complications of Glaucoma Surgery (pp. 107-112). New York: Oxford University Press. Bodnar Zm, Mamalis N (2013). Endophthalmitis and Toxic Anterior Segment Syndrome. In Agarwal A, Jacob S (Eds.), Complications in Ocular Surgery (pp. 253-68). Thorofare, NJ: SLACK Incorporated. Mamalis N, Edelhauser HF, Bodnar ZM (2013). Toxic Anterior Segment Syndrome. In Tasman W, Jaeger EA (Eds.), Duane's Ophthalmology (2013). Philadelphia: Wolters Kluwer/ Lippincott Williams & Wilkins.

Randall J Olson Olson RJ (04/01/2013). Horizontal Chopping Principles and Pearls. In Chang DF, Akahoshi t, arbisser LB, cionni rJ, nichamin LD, olson RJ, Packer M, Seibel BS (Eds.), Phaco Chop and Advanced Phaco Techniques (2nd Edition, pp. 11-19). Thorofare, NJ: SLACK Incorporated.

Geoffrey C Tabin Bujak mc, Gurang r, Demarchic e, ruit S, Tabin G (2013). Complications in Manual Small-Incision Cataract Surgery. In Agarwal A, Jacob S (Eds.), Complications in Ocular Surgery (pp. 167-80). Thorofare, NJ: SLACK Incorporated.

Haibo Wang Haibo Wang, M Elizabeth Hartnett. (2013). Chapter 40: Oxidative Stress and Jak/Stat Signaling; Neural and Vascular Interactions; Vegf Signaling in Angiogenesis. Pediatric Retina (2E). Wolter-Kluwers and Lippincott, Philadelphia, PA, USA.

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R E S E A R C H G R A N T S

Balamurali K Ambati, MD, PhD, MBA

Effects of Comp-ang1 on Vascular Permeability and Neavascularization $2,100

Fight for Sight Duration: 6/1/13–9/1/13

Defining the Mechanism of Comp-angiopoietin-1 Activity in the Diabetic Retina $18,000

PhRMA Foundation Duration: 7/1/13–6/30/14

Endoshield: Making Cataract Surgery Safer and Easier $40,000

Utah Governor's Office of Economic Development Duration: 5/1/12–5/31/13

The Role of sFlt in Corneal Avascularity $250,000

National Eye Institute Duration: 8/1/13–7/31/17

Endo-contact Lens for Corneal Protection in Cataract Surgery $35,000

University of Utah Research Foundation Duration: 6/1/12–5/31/13

Intraceptor Interference of VEGF Pathways $278,187

National Eye Institute Duration: 2/1/08–4/30/13

Retinal Health Analyzer for Novel Therapy and Early Diagnostics for AMD $20,000

Carl Marshall & Mildred Almen Reeves Foundation Duration: 12/1/12–8/31/14

The Role of Soluable Flt-1 and Raver2 in Ocular Vascular Demarcations $372,500

National Eye Institute Duration: 8/1/13–7/31/17

Interference of Vegf na

National Eye Institute Duration: 4/1/13–3/31/18

Caltech Wound Healing na

National Eye Institute Duration: 04/1/13–3/31/18

Pre-mRNA Interference of VEGF, VA Merit Award $650,000

Va Salt Lake city Health care System Duration: 10/1/09–9/13/13

SFLT $2,568,557

National Institutes of Health Duration: 4/1/08–4/30/13

The Role of SFLT in Corneal Avascularity $250,000

National Eye Institute Duration: 2/1/08–1/31/13

Alessandra Angelucci, MD, PhD

A Novel Approach for Mapping Single-cell Long-range Connections in the Cerebral Cortex $293,329

National Eye Institute Duration: 5/1/12–7/31/14

Parallel Pathways in Visual Cortex: Functional Connectivity of Output Pathways From Area V1 to Area V2 $372,500

National Eye Institute Duration: 8/1/13–7/31/16

Wolfgang B Baehr, PhD

Therapies for Retinal Degeneration Caused by NPHP5 Mutations $75,000

Foundation for Retinal Research Duration: 11/1/13–10/31/14

The Role of Nephrocystin-5 in Retinal Degeneration $34,366

National Eye Institute Duration: 8/1/12–7/31/14

Photoreceptor Ciliopathies: RP2, KIF17, and NPHP5 $354,073

National Eye Institute Duration: 5/1/12–4/30/16

Membrane Protein Trafficking $335,239

National Eye Institute Duration: 12/1/08–11/30/13

Core Vision Research Grant (Baehr & Bernstein) $173,129

National Eye Institute Duration: 7/1/10–6/30/15

Study of Retinal Degeneration $57,000

Foundation Fighting Blindness Duration: 08/1/10–7/31/13

Research Grants and Contracts

J O H N A . M O R A N E y E C E N T E R

2013-2014

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Margaret DeAngelis, PhD

Human Eye Repository for Studies of Age-related Macular Degeneration $20,000

Carl Marshall & Mildred Almen Reeves Foundation Duration: 12/1/12–8/31/14

Research to Understand the Genetic Epidemiology of Blinding Diseases of the Posterior Eye among Federally Recognized Native Americans $963,100

ALSAM Foundation Duration: 3/16/12–12/31/13

Identifying Underlying Mechanisms of Age-related Macular Degeneration $250,000

Edward N & Della L Thome Memorial Duration: 7/1/10–9/6/14

Kathleen B Digre, MD

Coalition for a Healthier Community for Utah Women and Girls $500,000

National Cancer Institute Duration: 9/1/11–08/31/16

yingbin Fu, PhD

A New Treatment Strategy for Age-related Macular Degeneration $40,00

Carl Marshall & Mildred Almen Reeves Foundation Duration: 9/30/12–8/31/17

Development of Effective Therapies for Leber Congenital Amaurosis $60,000

Knights Templar Eye Foundation Duration: 7/1/12–6/30/13

Strategies-Leber Congenital Amaurosis $80,000

E Matilda Ziegler Foundation Duration: 7/1/11–6/30/14

Cone Opsins in Photoreceptor Degeneration $309,406

National Eye Institute Duration: 9/30/12–8/31/17

Sabine Fuhrmann, PhD

Mechanisms Controlling RPE Development $376,250

National Eye Institute Duration: 1/1/10–12/31/13

Paul S Bernstein, MD, PhD

Nanosized Carotenoid Complexes with Plant Metabolities and Potential Delivery System for Treatment of Ocular Disorders $5,000

US Civilian Research and Development Duration: 3/22/13–3/21/15

Biochemical Studies in Support of the Next Generation AREDS Supplement for AMD $20,000

Carl Marshall & Mildred Almen Reeves Foundation Duration: 12/1/12–8/31/13

Mactel Macular Carotenoids $189,215

Lowy Medical Research Institute Duration: 11/1/13–5/14/14

Mactel Macular Carotenoids $147,600

Lowy Medical Research Institute Duration: 11/1/10–3/31/14

VLC-PUFAS in Dry AMD $100,000

Arnold and Mabel Beckman Foundation Duration: 7/1/13–6/30/14

Biochemistry and Pharmacology of Macular Cartenoids $372,916

National Eye Institute Duration: 3/1/13–2/28/17

Bam114341 $234,887

GlaxoSmithKline Duration: 5/1/11–12/31/14

Vpa Protocol $628,276

National Neurovision Research Institute Duration: 6/1/10–1/31/13

Age-related Eye Disease (AREDS) Study II $168,000

Emmes Corporation/National Eye Institute Duration: 6/1/06–Present

Alan S Crandall, MD

Oms302-Ilr-004 $48,270

Omeros Corporation Duration: 4/12/12–6/30/13

Cypass Glaucoma Implant $110,289

Transcend Medical, Inc. Duration: 1/1/11–12/31/14

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Gregory S Hageman, PhD

Genetic Susceptibility to Age-related Macular Degeneration $55,963

Columbia University Duration: 9/1/10–8/31/13

Characteristics of Genes and Pathways Associated with Chromosome 1-and Chromosome 10-directed AMD $500,000

Allergan/Voyant Biotherapy Duration: 12/1/12–11/30/13

Improved Characterization of High-risk Phenotypes in Early AMD, Employing Novel Imaging and Functional Modalities $400,000

Principal Investigators: Robyn Guymer; Gregory S Hageman

Macular Degeneration Foundation of Australia Duration: 10/4/11–10/4/14

Mary Elizabeth Hartnett, MD

Studies on Angiogenic Mechanisms and Safety Regarding Erythropoietin in Retinopathy of Prematurity: Seeking a Safe Treatment $90,000

march of Dimes Duration: 6/1/13–5/31/16

Endothelial Transmigration in Neovascular Age-related Macular Degeneration $365,050

National Eye Institute Duration: 4/1/12–3/31/17

Mechanisms of Angiogenesis in ROP $342,045

National Eye Institute Duration: 7/1/10–6/30/14

Robert O Hoffman, MD

G-Rop $9,512

University of Pennsylvania Duration: 9/30/12–8/31/13

E-Rop $78,711

University of Pennsylvania Duration: 07/01/10–06/30/14

Bryan W Jones, PhD

Normal Aging vs. Late Stage AMD Phenotypes $250,000

Edward N & Della L Thome Memorial Duration: 12/15/09–9/14/13

Bradley J Katz, MD, PhD

Blast Ocular Injury $718,099

Principal Investigators: Brittany Coats, yingbin Fu, Jason a Goldsmith, Bradley J Katz Kenneth L monson

Army Medical Research Acquisition Activity Duration: 9/1/12–8/31/16

Quark 007 $93,635

Quark Pharmaceuticals, Inc. Duration: 9/1/12–8/31/16

David Krizaj, PhD

Pressure Transduction and Neuroprotection in Glaucoma $18,500

University of Utah Research Foundation Duration: 7/1/12–6/30/13

Glaucoma Drugs $40,000

Utah Governor's Office of Economic Development Duration: 2/28/13–2/28/15

Characterization of Molecular Mechanisms of Ocular Blast Trauma $269,406

Army Medical Research Acquisition Activity Duration: 8/15/12–8/14/16

Role of Mechanosensation in the Retina $365,050

National Institutes of Health Duration: 12/1/12–11/30/16

Core Vision Research Grant $84,187

National Eye Institute Duration: 7/1/10–6/30/15

Regulation of Neurotransmission in the Retina $321,829

National Eye Institute Duration: 9/1/07–8/31/13

Ocular Blast Mechanisms $661,051

US Army Medical Research Acquisition Activity Duration: 8/15/12–8/14/16

Vlc-Pufas as in Dominant Stargardt $65,000

Principle Investigators: Paul S Bernstein; David Krizaj

Foundation Fighting Blindness Duration: 8/1/10–7/31/13

Edward M Levine, PhD

Core Vision Research Grant $87,287

National Institutes of Health Duration: 7/1/10–6/30/15

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Nick Mamalis, MD

Power Adjustment and Biocompatibility, Amend #21 na

Calhoun Vision Inc. Duration: 5/4/07–7/31/17

AquaLase for Removal of Residual Lens Epithelial Cells During Cataract Extraction na

alcon research, Ltd. Duration: 3/1/05–Present

Gross and Histopathologic Evaluation of Explanted Rabbit Eyes that had been Implanted with a New Intraocular Lens na

Advanced Medical Optics Duration: 3/1/05–Present

Evaluation of Removal of Lens Epithelial Cells in a Pig Eye na

alcon research, Ltd. Duration: 02/01/05–Present

Assessment of Capsular Bag Opacification after Implantation of Piggy Back IOL's and a Dual-optic IOL na

Visiogen, Inc. Duration: 01/01/05 –Present

Robert E Marc, PhD

Challenges in Imaging (ARRA)-UCSB Subcontract $89,932

National Science Foundation Duration: 10/1/09–9/30/13

Core Vision Research Grant (Supplement) $300,000

National Eye Institute Duration: 7/1/12–6/30/13

Core Vision Research Grant (Main) $29,743

National Eye Institute Duration: 7/1/10–6/30/15

Core Vision Research Grant $167,337

National Eye Institute Duration: 7/1/10–6/30/15

Retinal Remodeling $536,248

National Eye Institute Duration: 4/1/12–3/31/13

Structural Neurochemistry of Retinal Circuits $624,982

National Eye Institute Duration: 12/1/11–11/30/16

Mark D Mifflin, MD

CPTS $109,350

Jaeb center for Health research Duration: 3/1/12–6/30/17

Evaluation of Topical Antibiotics/Risk of Endophthalmitis with Intravitreal Injection $20,000

Allergan, Inc. Duration: 1/1/07–Present

Cornea Donor Study: National Multicenter Investigation to Study the Effect of Age on Cornea Transplant Outcome $27,134

National Eye Institute Duration: 8/1/99–7/31/13

Majid Moshirfar, MD, FACS

ACOS Kxl-001 na

Avedro, Inc. Duration: 9/1/12–6/30/13

Randall J Olson, MD

A Prospective Multi-centered Study of AcrySof Glistenings $25,000

Advanced Medical Optics, Inc. Duration: 6/1/08–Present

Assessing Post-occlusion Surge in Vacuum Flow Systems $10,000

Bausch & Lomb Duration: 05/1/08–Present

Visualizing MRSA Response to BAK +/- Gatifloxacin $8,000

Allergan, Inc. Duration: 5/1/08–Present

An Eyebank Comparison of Corneal Endothelial Damage with Dispersive OVDs $6,000

Advanced Medical Optics, Inc. Duration: 4/1/08–Present

Recovery of Bacteria from Intraocular Injection in Cadaver Eyes $25,000

Allergan, Inc. Duration: 8/1/07–Present

Differentiating the Effect of BAK and 4th Generation Fluoroquinolones against MRSA $12,000

Allergan, Inc. Duration: 4/1/07–Present

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Debra A Schaumberg, ScD, OD, MPH

Omega-3 Fatty Acids for Prevention of Dry Eye Disease: Vital AMD $496,227

National Eye Institute Duration: 4/1/13–8/31/17

Vital AMD: Prevention of AMD in the Vitamin D and Omega-3 Trial $94,192

National Eye Institute-Subaward from Brigham & Womens Hospital Duration: 4/1/13–8/31/17

Effects of Vitamin D and Omega-3 Fatty Acids on Infectious Diseases and hCAP18 $31,645

National Eye Institute-Subaward from Brigham & Womens Hospital Duration: 4/1/13–8/31/17

Randomized Trial of Vitamin D & Omega-3 Fatty Acids for Diabetic Kidney Disease $19,144

National Eye Institute-Subaward from University of Washington Duration: 4/1/13–8/31/15

Randomized Trial of Vitamin D and Omega-3 Fatty Acids for Diabetic Kidney Disease $2,004,523

National Institute of Diabetes and Digestive and Kidney Diseases Duration: 9/1/10–8/31/15

R01 EY017362 Genetic Epidemiology of Age-related Macular Degeneration $2,563,818

National Eye Institute Duration: 1/1/07–12/31/13

Michael P Teske, MD

CLEAR-IT 3 na Regeneron Pharmaceuticals, Inc. Duration: 4/1/07 –Present

The Natural History of Geographic Atrophy Progression (GAP) Study $75,900

alcon research Ltd Duration: 1/31/08–Present

Ning Tian, PhD

Development of Synaptic Pathways $263,900 in Retina (Supplement)

National Eye Institute Duration: 4/1/12–3/31/13

Development of Synaptic Pathways $383,690 in Retina

National Eye Institute Duration: 4/1/11–3/31/16

Albert T Vitale, MD

Must Follow Up Study $45,521

Johns Hopkins University Duration: 05/1/12–4/30/14

Phase II/III Study of Encapsulated Human NTC-201 Cell Implants Releasing Ciliary Neurotrophic Factor (CNTF) for Participants with Retinitis Pigmentosa Using Visual Acuity as Primary Outcome na

Neurotech USA, Inc. Duration: 4/1/07–Present

Multicenter Uveitis Steroid Treatment (MUST) Trial $281,000

Johns Hopkins University Neuro-education Initiative Duration: 12/1/05–Present

A Multicenter Study of the Efficacy and Safety of the Human Anti-TNF Monoclonal Antibody Adalimumab as Maintenance Therapy in Subjects Requiring High-dose Corticosteroids for Active Non-infectious Intermediate-, Posterior-or Pan-uveitis na

Abbott Laboratories Duration: 11/30/10–Present

Comparison of AMD Treatment Trial (CATT)-Lucentis-Avastin Trial na

Emmes Corporation/National Eye Institute Duration: 04/1/07–Present

Phase II- Clinical Trial: A Multicenter Randomized Double-masked Controlled Study to Evaluate the Safety and Efficacy of an Intravitreal Fluocinolone Acetonide (0.5 or 2 mg) Implant in Patients with Noninfectious Uveitis Affecting the Posterior Segment of the Eye, American Study na

Bausch & Lomb Duration: 1/1/03–Present

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Judith E A Warner, MD

A Multicenter, Double-blind, Randomized, Placebo-controlled Study of Weight-reduction and/or Low-sodium Diet plus Acetazolamide vs Diet plus Placebo in Subjects with Idiopathic Intracranial Hypertension with Mild Visual Loss (IIHTT) $80,500

neuro-ophthalmology research Disease Investigator Consortium Sub Investigator Duration: 11/30/09–11/30/15

Liliana Werner, MD, PhD

Evaluation of a New IOL $8,529

Principal Investigators: nick mamalis, Liliana Werner

PhysIOL SA Duration: 11/1/12–4/30/13

Evaluation of a New IOL $87,515

Principal Investigators: nick mamalis, Liliana Werner

Abbott Medical Optics Duration: 2/10/12–4/30/14

Evaluation of a New IOL $10,986

Principal Investigators: nick mamalis, Liliana Werner

Advanced Vision Science, Inc. Duration: 10/1/10–9/30/13

Evaluation of a New IOL $77,568

Principal Investigators: nick mamalis, Liliana Werner

Anew Optics, Inc. Duration: 5/1/10–9/30/14

Silicone Oil in the Eye $267,262

Principal Investigators: nick mamalis, Liliana Werner

PowerVision, Inc. Duration: 3/30/09–Present

Jun yang, PhD

Formation and Function(s) of the Usher 2 Protein Complex in Photorecptors $80,000

E Matilda Ziegler Foundation Duration: 1/1/11–12/31/13

Gene Therapy for Retinitis Pigmentosa in Usher Syndrome Type 2 $50,000

Foundation Fighting Blindness Duration: 8/1/10–7/31/13

Analysis of the Interaction Between a Novel Serine/Threonine Protein Phosphatase and the Usher Syndrome Type2 Protein Complex $60,000

Knights Templar Eye Foundation Duration: 7/1/13–6/30/14

The Function of PDZD7 in the Cochlear Hair Cells $25,000

Hearing Health Foundation Duration: 7/1/13–6/30/14

Understanding and Restoring the USH2 Complex in Cochlear Hair Cells $20,000

National Organization for Hearing Research Duration: 7/1/13–6/30/14

Involvement of C8ORF37 in the Inherited Retinal Degenerations and Ciliopathies $28,000

University of Utah Research Foundation Duration: 7/1/13–6/30/14

Research to Prevent Blindness Special Scholar Award $100,000

Research to Prevent Blindness Duration: 7/1/13–12/31/14

Formation and New Components of the Usher 2 Protein Complex in Photoreceptors $345,322

National Eye Institute Duration: 4/1/11–3/31/16

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Balamurali K Ambati, MD, PhD, MBA

COMP-ang1 Improves Diabetic St. Louis, MO Vascular Hyperpermeability. Washington University Diabetes research center

Raver-2 Controls Flt-1 Alternative Rio de Janeiro, Brazil Splicing. troutman-Veronneau Lecture, Pan-American Association of ophthalmology

From Training to Clinician-science Lexington, KY careers. Vision Health Summit

Targeted Nanoparticles Inhibit Paris, France and Regress CNV. International Society of Ocular Pharmaceutics and therapy

Complex Cornea Cases. Black Rapid City, SD Hills regional eye conference

Alessandra Angelucci, MD, PhD

Keynote Speaker, Corticocortical Rio de Janeiro, Brazil Connections in the Primate Visual Cortex: Structure and Function. Brazilian Society for neuroscience Meeting

Invited Speaker, Department of Madrid, Spain Morphology, Autonoma University medical School

Invited Speaker, Department Philadelphia, PA of Neuroscience, University of Pennsylvania

Honorary Lectureship, Department manchester, england of optometry and neuroscience, UMIST, 2001-Present

Seminar, The Spatial Logic of Chicago, IL Intra-areal and Inter-areal Connections within and between Areas V1, V2, V3, and V5/MT of the Macaque Visual Cortex. Computational Neuroscience Seminar Series, Department of Mathematics, University of chicago, 1999-Present

Invited Speaker Seminar, Salt Lake City, UT Circuits for Spatial Integration of Information in the Primate Visual Cerebral Cortex. math Biology Seminar Series, Department of Mathematics, University of Utah, 2002-Present

Invited Speaker Seminar, Rewiring the Oxford, England Brain: Role of Afferents and Targets in the Generation of Specific and Patterned Connections. Departmental Lecture, University Laboratory of Physiology, Oxford University, 1998-Present

Invited Speaker Seminar, Rewiring the Pisa, Italy Brain: Role of Afferents and Targets in the Generation of Specific and Patterned Connections. Department of Physiology, consiglio nazionale Delle ricerche

Wolfgang B Baehr, PhD

Curing Dominant Retinitis Salt Lake City, UT Pigmentosa and cone Dystrophy in Animal Models. Foundation Fighting Blindness, Moran Eye Center

William R Barlow, MD

Evaluating Heat Production of Modified San Francisco, CA Phacoemulsification Handpiece, Barlow Wr. american Society of Cataract and Refractive Surgery/ ASOA Symposium and congress

emerging trends and Paradigm Lubbock, tX Shifts in Glaucoma Management. Chaya C, Kim J. 30th Annual Texas Tech University Clinical Update for Comprehensive Ophthalmology

Innovations in Glaucoma Surgery: Salt Lake City, UT In Search of a New "Gold" Standard. Vincent B, chaya c. north Star optometry Seminars, John a. Moran Eye Center, University of Utah

corneal Surgery and eye Banking Kigali, rwanda in Sub-Saharan Africa. First Scientific congress of the college of ophthalmology of eastern, centeral, and Southern africa

International Outreach in Tibet. Tucson, AZ the Jorge rodriguez, mD, mPH, memorial Lectureship

Paul S Bernstein, MD, PhD

Plenary Lecturer, Royal College Liverpool, England of Ophthalmology Meeting

Plenary Lecturer, International Tokyo, Japan Blue Light Society Meeting

Plenary Lecturer, macular cambridge, england carotenoid conference, Downing college

This is a partial list of Moran National and International Presentations

N A T I O N A L A N D I N T E R N A T I O N A L P R E S E N T A T I O N S 2013

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Keynote Lecturer, Iranian Tehran, Iran ophthalmological Society

Plenary Lecturer, Gordon Ventura, ca conference on carotenoids

moderator, Speaker, and Poster Paris, France Presenter, International Society for ophthalmic Pharmacology and Therapeutics Meeting

Macula Society Meeting, Tucson, AZ 2010-Present

One Platform Presentation and Fort Lauderdale, FL 4 Posters, Association for Research in Vision and ophthalmology, 2010- Present

Platform Presentation, Retina New York, NY Summit, 2010- Present

Poster and Platform Presentation, Seattle, WA Association for Research in Vision and ophthalmology

Poster Presentation, American Toronto, Canada Society of Retina Specialists

Platform Speaker, RD2010 Meeting, Montreal, Canada 2010-Present

Invited Speaker and Moderator, Rome, Italy International Symposium on Ocular Pharmacology and Therapeutics, 2009-Present

Invited Speaker and Panelist, Stuttgart, Germany Hohenheim consensus conference, 2010-Present

Invited Speaker to Educate Moscow, Russia russian opthalmologists on the Value of Nutritional Supplements for age-related macular Degeneration. Saint Petersburg, 2010- Present

Invited Speaker, Royal Nottingham, England ophthalmological Society, elizabeth thomas age-related Macular Degeneration Symposium, 2011-Present

Invited Speaker, Mette Warburg Copenhagen, Denmark Annual Lecture, University of copenhagen, Denmark

Inivited Lecturer, Institute for Novosibirsk, Russia Chemical Catalysis and Combustion, russian academy of Sciences, Siberian Branch

Invited Speaker, American Academy San Francisco, CA of Ophthalmology Retina Sub-specialty Day, 2009-Present

Invited Lecturer, Ophthalmic San Francisco, CA Photographers Society, 2009-present

Invited Speaker, Bascom Palmer Miami, FL Eye Institute, 2010-Present

Invited Speaker, Florida International Miami, FL University, 2010-Present

Invited Speaker, Angiogenesis Miami, FL Meeting, Bascom Palmer Eye Institute

Invited Speaker, American Optometric Orlando, FL Association, 2010-Present

Invited Speaker, Supply Side West Las Vegas, NV

Craig J Chaya, MD

Healthy eyes, chaya c. Wellness tamuning, Guam Lecture Series, SDa Guam clinic

Alan S Crandall, MD

managing Glaucoma and cataract. ayr, Scotland Clinical Experience with LenSx Femtosecond Laser. IOL Exchange: Tips and Tricks. National Institutes of Health 3rd ayr cataract Surgery Course, University Hospital Ayr

Restoring Sight and Opening Eyes Salt Lake City, UT Towards Peace in Sudan. Alta Club; town club

Hard Lenses with Loose Zonules in Playa del carmen, PXe Case. The ABCs of CTRs. American Mexico Society of Cataract and Refractive Surgery 2010 Winter Update, 2010-Present

The Future of Cataract Surgery: Vienna, Austria Experience and Results. Course: IC-14 Management of Co-existing Cataract and Glaucoma: Surgical Challenges. Malpositioned Lenses: techniques of Surgical management. european Society of cataract and Refractive Surgery, 2011-Present

Panelist on Panel Discussion, amsterdam, Femtosecond Cataract Instrumentation: Netherlands are all technolgies equally Good? crandall aS, Lindstrom r, malyugin B, Piovella MN, Stevens J. Panelist on Panel Discussion: Novel Glaucoma Surgical Devices: The Potential Oppor- tunities in Established and Emerging markets, crandall aS, Belkin m, chew Pm, Feijoo JG, nardi m, Samuelson tW. ophthalmology Futures european Forum, The Royal Tropical Institute (KIT)

Surgical management of amsterdam, Malpositioned Lenses, Malyugin B, Netherlands assia e, rosenthal K, Pfeifer V, tassignon mJ, crandall a. manage- ment of cataract in challenging Cases, Vasavada AR, Biro Z, Osher R, Spalton D, Crandall A. Advanced Micro-sheathed Co-axial Phaco/Microphaco Techniques and Bi-axial Microphaco in Challeng- ing Cataracts: a Video Course, mehta K, Packard r, malyugin B, Mehta C, Crandall A. XXXI Congress of the european Society of cataract and Refractive Surgery

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Alan S Crandall, MD

IOL Exchange, Crandall AS, Masket S. Chicago, IL american academy of ophthal- mology, chicago 2012-Present

Industry Panel Discussion: Glaucoma San Francisco, CA Devices, Moderators: Crandall AS, Hoskins HD. Panel Members: Kuschnereit r, rady Je, Kunst G, azoulay K. new Horizons Forum, Glaucoma Research Foundation

Complexities Encountered with San Francisco, CA cataract Surgery in Glaucoma Patients, Crandall AS. 17th Annual Glaucoma Symposium

Managing Difficult Cannulation in San Francisco, CA canaloplasty and 360 trabeculotomy, crandall aS. american Glaucoma Society 23rd Annual Meeting

Canaloplasty Conundrum. Coexisting San Francisco, CA Cataract and Glaucoma: Tips for Uneasy Relationship, Khalil AK, crandall aS, agarwal a, malyugin Be, Jacob S, Crandall AS. Toxic Anterior Segment Syndrome Following cataract Surgery, mamalis n, olson rJ, crandall AS, Chan TK. Expert Techniques for Iris repair, Snyder me, rosenthal KJ, Masket S, Crandall AS, Ahmed IK. Phacoemulsification in Difficult and Challenging Cases, Hoffman RS, Ahmed IK, Akaishi L, Braga-Mele RM, Crandall AS, Fine IH, Masket S, osher rH, Packer m, cionni rJ. Deep Sclerectomy and canaloplasty for new Glaucoma Surgeons, mehta cK, crandall aS, Scharioth GB, mehta Kr, Malyugin BE. Mission Possible: Phacoemulsification in Difficult and challenging cases, Pandey SK, Sharma V, crandall aS, agarwal a, Malyugin BE, Ahmed IK, Osher RH, Packer M, Cionni RJ, Vasavada AR. Surgical Management of Subluxated Lenses, Assia EI, Rosenthal KJ, malyugin Be, Pfeifer V, crandall aS. Management of Difficult Cataracts and Challenging Situations, Vasavada AR, Crandall AS, Mamalis N, miller Km, osher rH, masket S. Tackling Weak Zonules and Using Capsular Tension Devices, Ahmed IK, cionni rJ, crandall aS, masket S, Osher RH, Rosenthal KJ. Increased risks for Performing cataract Surgery in Angle Closure Patients, Crandall AS. Intraocular Lens Exchange and Repositioning Techniques, Crandall AS, Ahmed IK, Condon GP. Scleral- fixated IOLs, Crandall AS. American Society of Cataract and Refractive Surgery /ASOA Symposium and congress

Intraoperative Device to Stabilize the Philadelphia, PA Lens. Femtosecond Lasers. Scheie eye Institute 139th Anniversary Meeting, Perelman School of medicine, University of Pennsylvania

Alternatives to Tubes and Trabs. San Antonio, TX Bench-to-Practice I. Bench to Practice II. Crandall Video I. Crandall Video II. Video Symposium, San antonio ophthalmic Symposium

Donnell J Creel, PhD

Albinism Update. Chinese National Chongqing, China congress of Visual Physiology

Scotopic Dim Blue and Red ERG Stimuli. Chongqing, China International Meeting of ISCEV

Alison Crum, MD

Featured Speaker, Neuro-Ophthalmic Deer Valley, UT Emergencies. Utah Ophthalmology Society, Summer conference for ophthalmologists.

Margaret M DeAngelis, PhD

Characterizing Pathways/Mechanisms Gyeongju, Korea Underlying Age-related Macular Degeneration. Korean Ophthalmology Society Symposium

A Role for Genetics of Ethnically Seoul, Korea Diverse Populations in Studying Complex Diseases. International Retinal Society Symposium, Seoul National University Hospital

Update on Age-related Macular Seattle, WA Degeneration: The Role of Vitamin D Metabolism and BMI in Women’s Eye Health. Women’s eye Health annual Advisory Board/Executive Committee Meeting, Association for Research in Vision and ophthalmology

The Genetics of Age-related Macular Boston, MA Degeneration: An Overview. Symposium, Massachusetts Eye and Ear Infirmary, 2003-Present

Characterizing Disease Pathways in Salt Lake City, UT Age-related Macular Degeneration: Integrated Analysis of Genetics, Gene Expression, and Epigenetics. University of Utah School of Medicine clinical Faculty Day

Kathleen B Digre, MD

Update in Internal Medicine: Headache Park City, UT Update 2013

Shedding Light on Photophobia. Portland, or Grand Rounds, Emory University

Shedding Light on Photophobia. Portland or Headache: Beware the Perfect Storm. troubling thirds. the William t. Shults Lecture, Legacy Health Care, Devers eye center

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Photophobia: What Does the Cornea Boston, MA Tell Us. The 28th Biennal Cornea conference, Schepens eye research Institute, Massachusetts Eye and Ear, Harvard Medical School

Low Pressure Syndromes. Scottsdale Scottsdale, AZ Headache Symposium

Come Into the Light: Understanding Jackson, MS Photophobia. The James J Corbett Lecture, University of Mississippi

NOVEL Update. North American Snowbird, UT neuro-ophthalmology Society

yingbin Fu, PhD

Precise Gene Editing in Vivo. National Potomac, MD Eye Institute Audacious Goals Development Meeting

The Proteolytic Activity of HTRA1 is Fort Lauderdale, FL Responsible for Its Pathological Role in Polypoidal choroidal Vasculopathy, Zhang t, Jones a, Wang S, Pugh en, Baehr W, Fu Y. Genetic Deletion of S-opsin Prevents Rapid Cone Degeneration in a Mouse Model of Leber congenital amaurosis, Kumar S, Berriochoa Z, Jones a, and Fu y. The Association for Research in Vision and Ophthalmology Annual Meeting

Sabine Fuhrmann, PhD

Axin2 Disruption Causes Ocular Seattle, WA Defects During Mouse Eye Develop- ment, Fuhrmann S, Gibbons m, Alldredge, A. Association for Research and Vision in ophthalmology

Physiology and Developmental Provo, UT Biology Department, Brigham Young University

Gregory S Hageman, PhD

Keynote Speaker, Toward the Develop- Copenhagen, Denmark ment of Therapeutics and Diagnostics for Age-related Macular Degeneration and Its Co-segregating Diseases. Invited Speaker, Toward a Refined Understanding of Age-related Macular Degeneration: A New Era. European Society of ophthalmology

Keynote Speaker, age-related macular tartu, estonia Degeneration: Overview, Pathology, and the complement Pathway. Keynote Speaker, age-related macular Degeneration: Reticular Pseudodrusen and Therapeutic Development. Keynote Speaker, Toward a Refined Understanding of Age-related Macular Degeneration: A New Era. Pathology, Genetics, Diagnostics, and Treatment of eye Diseases

Keynote Speaker, Toward a Refined Nottingham, England Understanding of the Biology and Genetics of Age-related Macular Degeneration. Elizabeth Thomas Seminar

Invited Speaker, Toward a Refined Paris, France Understanding of the Genetics and Biology of age-related macular Degeneration. DiaxonHit and Allergan, Inc

Invited Speaker, Phenotypic Variations Paris, France in Dry age-related macular Degeneration. Macula of Paris 2013

Invited Speaker, The Genetics of Paris, France Age-related Macular Degeneration. Invited Speaker, Toward a Refined Understanding of the Biology of Age-related Macular Degeneration through Genetic Analyses. Invited Speaker, Toward the Development of Therapeutics and Diagnostics for Age-related Macular Degeneration and Its Co-segregating Diseases. Retina Conference, University Paris Descartes

Invited Speaker, Toward a Refined Philadelphia, PA Understanding of the Biology and Genetics of Age-related Macular Degeneation: Therapeutic and Diagnostic Implications. Age-related Macular Degeneration Scientific Input Engagement

Toward a Refined Understanding of the Chicago, IL Biology and Genetics of Age-related Macular Degeneration. Applied Genetic Technologies Corporation

Presenter, Update: Genetics, Biology, Irvine, CA and clinical aspects of age-related Macular Degeneration. Allergan, Inc

Meeting Presentation, Update: Salt Lake City, UT Genetics, Biology, and Clinical Aspects of Age-related MacularDegeneration. Sequenom, Inc

Toward the Development of Salt Lake City, UT Therapeutics and Diagnostics for Age-related Macular Degeneration and Its Co-segregating Diseases. John A. Moran Eye Center, Advisory Board Meeting

Moran Center for Translational Salt Lake City, UT Medicine: Toward the Development of Diagnostics and Therapeutics for Age-related Macular Degeneration. Total Quality Management Meeting, John a moran eye center

Resident Lecture, Anatomy of the Eye. Salt Lake City, UT Structure, Function, and Pathology of the Choroid-RPE-Retina-Vitreous Complex. John A Moran Eye Center, University of Utah

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Gregory S Hageman, PhD

Invited Speaker, Toward a Refined Salt Lake City, UT Understanding of Age-related Macular Degeneration: Therapeutic and Diagnostic Implications. University of Utah Health Sciences Council, University of Utah

Invited Speaker, Toward a Refined Salt Lake City, UT Understanding of the Biology and Genetics of Age-related Macular Degeneration: Therapeutic and Diagnostic Implications. Department of Biochemistry, research-in-Progress Seminar, University of Utah

Presenter, Community Groups. Iowa City, IA Various Lectures and Presentations Have Been Given to Administrators, Faculty, and Staff of The University of Iowa; Local Hospitals (including St. Luke's Hospital, mercy Hospital, the Veteran's Administration Medical Center, and Mercy Medical Center). LifeNet, ISOPO, Iowa Donor Network; The Iowa City Medical Examiner; Local Retirement Centers (Melrose Meadows, Atrium Village, Cottage Grove, Methwick Manor), Senior Centers/Iowa City, Amana Clubs; and Other Organizations. These are Numerous (>100) and are Not Listed Individually, 1997-Present

Various television (Channel 2 News Iowa City, IA Health Report); newspapers (Cedar Rapids Gazette, Iowa City Press Citizen); Radio (WMT Dottie Ray Show, KXIC Radio, University Hospitals Today); and interviews. Articles pertaining to research published in numerous publications, including Iowa Eye, Iowa Life Gift, and Pacemaker, 1997-Present

moderator. arnold and mabel newport Beach, ca Beckman Initiative for Macular research conference

Invited Speaker, Toward a Refined Bethesda, MD Understanding of the Biology and Genetics of Age-related Macular Degeneration. R24 Outcomes Meeting, National Eye Institute

Visiting Professor, Toward a Refined Los Angeles, CA Understanding of the Biology and Genetics of Age-related Macular Degeneration: Therapeutic and Diagnostic Implications. University of california

Invited Speaker, Toward a Refined Miami, FL Understanding of the Biology and Genetics of Age-related Macular Degeneration: Therapeutic and Diagnostic Implications, Angiogenesis, Exudation, and Degeneration

Mary Elizabeth Hartnett, MD

The Role of Age-related CCR3 Seattle, WA Activation in Choroidal ECS in Age-related Macular Degeneration. Association for Research in Vision and ophthalmology

targeted Silencing of VeGF reduces La Jolla, ca Aberrant Intravitreal Angiogenesis in Model of Retinopathy of Prematurity. american ophthalmological Society Annual Meeting

Rap1 GTPase Improves RPE Dana Point, CA Barrier Integrity and Resists Choroidal Neovascularization. Macula Society Meeting

Moderator for Basic Science/Age- Dana Point, CA related Macular Degeneration and Diabetic Retinopathy. Macula Society Meeting

Invited Speaker, Retinopathy of Louisville, KY Prematurity: Current Clinical management. ophthalmology Grand Rounds, University of Louisville School of Medicine

Invited Speaker, Insights Into Salt Lake City, UT Recurrent Neovascularization after Anti-VEGF Treatment in Retinopathy of Prematurity. University of Utah, John moran eye center

Retinopathy of Prematurity. Salt Lake City, UT Utah North Star Optometry Seminars, John a. moran eye center, 2011-Present

Robert O Hoffman, MD

Visiting Professor Lecture, Rapid City, SD Retinoblastoma. Black Hills Regional Eye Institute, 2007-Present

Bryan W Jones, PhD

Plasticity in the Degenerate Retina. Milwaukee, WI medical college of Wisconsin

Anatomy and Physiology of the Seattle, WA Degenerating Visual System. american academy of optometry

Retinal Remodeling and Plasticity. Bethesda, MD National Institutes of Health, National Eye Institute

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David Krizaj, PhD

Unorthodox Calcium Signaling in the Salt Lake City, UT Retina. Research Seminar, Department of neurobiology and anatomy, University of Utah

molecular mechanisms of Glaucoma. Sarasota, FL Neuroprotection in Glaucoma is Achieved by Blocking Mechanosensitive Ion Channels in Retinal Ganglion Cells. International Society for Eye Research

Does Mechanosensation Contribute to Moscow, ID Pressure-induced Light Perception and Glaucoma? ryskamp D. research Seminar, University of Idaho

Saving Sight by Curing Glaucoma. Irvine, CA allergan

Novel Modes of Calcium Signaling in Cincinnati, OH the Vertebrate Retina. Cincinnati children’s Hospital medical center

Photoreceptor calcium Signaling Steamboat Springs, co Downstream from the outer Segment. the role of Store-operated Calcium Entry in Intracellular Calcium Regulation in Mammalian Rods and müller Glia. Presented by t. molnar. FaSeB Summer research conference on the Biology and chemistry of Vision

Molecular Coupling Between TRPV4 Seattle, WA and Aquaporin 4 Channels Mediates Osmosensation in Müller Glia. Mechanisms of Retinal Cell Swelling, Volume Sensing, and mechanical Excitotoxicity, Ryskamp D. Annual Meeting Association for Research in Vision and ophthalmology

Polymodal Integration of Sensory Tucson, AZ Information in the Retina. University of arizona

No Pressure–Calcium Multitasking in San Francisco, CA rGcs. close to nature’s Secrets. Festschrift for David Copenhagen

Non-orthodox Calcium Signaling in the NA Retina. Department, Neurobiology and anatomy research Seminar

Invited Seminar at Colorado State Ft. Collins, CO University, 2008-Present

Nick Mamalis, MD

What Do you Know about Singapore Postoperative TASS? How to Prevent it? Mamalis N. Asia Pacific Association of Cataract and Refractive Surgeons 26th Annual Meeting

Capsular Bag Opacification with a Amsterdam, New Silicone Oil-filled Accomodating Netherlands Intraocular Lens, Mamalis N, Werner L, Floyd a, Liu e, Stallings S, morris c.

How Many Multifocal IOLs are Explanted and Why? Survey on Foldable IOLs Requiring Explantation or Secondary Intervention: 2012 Update, Mamalis N, Floyd A, Liu E, Stallings S. Pathologic comparison of Asymetric or Sulcus Fixation of Three-piece Intraocular Lenses with Square versus Round Anterior Optic edges, Werner L, ollerton a, Strenk S, Strenk L, Mamalis N. XXXI Congress of the european Society of cataract and Refractive Surgeons

Video Symposium of Challenging Aventura, FL Cases and Complications Management during cataract Surgery. Vitreous challenges in anterior Segment Surgery. Ethics Interactive. American Society of Cataract and Refractive Surgery /ASOA Winter Update, Turnberry Isle, Miami

Binkhorst Lecture: Intraocular Lens San Francisco, CA Evaluation: What A Long, Strange Trip It's Been. Mamalis N, Werner L. Coauthors: Kirk K, Jaber RM, Strenk SA, Strenk Lm. Pathological assessment of Complications with Asymmetric or Sulcus Fixation of Square-edged Hydrophobic Acrylic IOLs. Poster Session. Capsule Bag Opacification with New Silicone-oil-filled Accomodating IOL, Floyd AM. Coauthors: Liu ET, Stallings SL, morris ce, Werner L, mamalis n. Effective Communication Skills: Tips for Public Speaking, Writing, and Publishing, Mamalis N. Survey of Foldable IOLs Requiring Explantation or Secondary Intervention: 2012 Update, Mamalis N, Floyd AM, Liu ET, Stallings SL. Toxic Anterior Segment Syndrome: Update on Most Common causes, mamalis n, Bodnar Zm, Stallings SL. Biocompatibility and Safety of Modified Light-adjustable Lens in rabbit model, Stallings SL. Coauthors: Floyd AM, Liu ET, Morris CK, Werner L, Mamalis N. Evaluation of New Single-piece 4 Percent Water Content Hydrophobic Acrylic IOL in Rabbit Model, Liu ET. Coauthors: Ollerton AI, Stallings SL, Floyd AM, Werner L, mamalis n. american Society of Cataract and Refractive Surgery Symposium on Cataract, IOL, and Refractive Surgery

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Robert E Marc, PhD

Jules Stein annual retreat na Keynote Speaker

National Eye Institute Invited Lecturer NA

Mark D Mifflin, MD

Cornea Time Preservation Study. Salt Lake City, UT Utah Ophthalmologic Society 34th annual conference

Majid Moshirfar, MD, FACS

Phakic IOL: Verisyse versus Vision San Francisco, CA Lens. Change in Keratometry Over Time Following LASIK and PRK. american Society of cataract and Refractive Surgery

Artificial Cornea and Femtosecond Midway, UT Laser Assisted Cataract Surgery. Utah Optometric Association, 2013 Annual Congress, Zermott Resort

Management of Infections and Salt Lake City, UT Non-infectious Inflammation after LASIK and PRK Surgery. John A. Moran Eye Center, University of Utah

Harald E Olafsson, OD

Utilization of Hybrid Lenses Riyadh, Management of Irregular Corneas Kingdom of Saudi Arabia and Significant Astigmatism. Management of Astigmatism Using Contact Lenses. Treatment of Irregular corneas with contact Lenses. King Fahd cultural center

Case Studies in Clinical Contact Lens Midway, UT Care. Utah Optometric Association Annual Convention

Contact Lenses a,b,.......to z. Salt Lake City, UT northstar regional optometric Symposium, University of Utah, John a. moran eye center

Randall J Olson, MD

tullos o. coston Lecturer, Why are oklahoma city, oK 20/20 Patients Still Unhappy after cataract Surgery? Dean mcGee eye Institute, University of Oklahoma

Dean McGee Eye Institute Lecture, Oklahoma City, OK What resulteth From a minor Phaco Tip Change? University of Oklahoma, Department of ophthalmology

Speaker, Toxic Anterior Segment San Francisco, CA Syndrome Following cataract Surgery. Advanced Phaco Skills. Microincision Phaco Technique with No Induced Astigmatism for Premium IOL. Learning Phaco Chop: Pearls and Pitfalls. Session moderator, Hot topics in cataract Surgery: Femtosecond and IOL Controversies. Intraocular Surgery Phaco techniques and technology. american Society of cataract and Refractive Surgey Annual Meeting

Speaker, Pseudophakic Dysphotopsia. Kona, HI Session moderator, complicated cases in cataract Surgery. Hawaiian eye Symposium

What Bothers Patients after San Diego, CA Successful cataract Surgery? University of California San Diego, Shiley eye center

What Outcomes Really Matter Los Angeles, CA after Cataract Surgery? Jules Stein Eye Institute, University of california, Los angeles Department of ophthalmology

Invited/Visiting Professor, A Lesson Iowa City, IA in Pursuit of New Understanding via Clinical Research. University of Iowa Carver College of Medicine, Department of ophthalmology research Day

Bhupendra C Patel, MD, FRCS, FRC

Cosmetic Surgery Forum. Las Vegas, NV Facial Cosmetic Surgery Meeting, 2007-Present

Jeff Pettey, MD

Effective Communication During Salt Lake City, UT Patient Encounters. Resident Lecture, John a. moran eye center

Debra Schaumberg, ScD, OD, MPH

epidemiology and risk Factors for taormina, Sicily Meibomian Gland Dysfunction. International Workshop on Contact Lens Discomfort: Report of the Subcommittee on Clinical Trial Design and Outcomes. Seventh International conference on the tear Film and Ocular Surface: Basic Science and Clinical Relevance

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Geoffrey C Tabin, MD

Development of a Successful Eye Care Kigali, Rwanda System in a Developing Nation: Lessons from Nepal. First Scientific congress of the college of ophthalmology of eastern, central, and Southern africa

Himalayan cataract Project. melbourne, australia ranZco annual congress, 2012-2013

Impossible Dreams: Everest and Los Angeles, CA Eradicating World Blindness. UCLA Health, David Geffen School of medicine

Conversation with Dr. Geoff Tabin. Midway, UT White cap Summit, White cap’s annual Dental conference

Yale Eye Center. Connecticut Society Farmington, CT of eye Physicians

Haibo Wang, MD, PhD

Activation of Rap1 Prevents Tumor Seattle, WA necrosis Factor alpha-induced roS Generation in RPE, McCloskey M, Wittchen ES, Hartnett ME. Association for research in Vision and ophthalmology

Barbara M Wirostko, MD

Invited Speaker, Early-stage Startup Seattle, WA Education Course, Companies: Strategies for entrepreneurship in Ophthalmology. Poster Presentations, Delivery of Human Growth Hormone via DSM’s Poly(ester amide), Berard J, Zupancich J, Hecka A, Mihov G, Reiver S, Thies J, Messier K, Wirostko B, Rafii M. Corneal Wound Healing model in new Zealand White rabbits for Evaluating Persistent Corneal epithelial Defects, Gum G, Wirostko B, Rafii MJ, Pritt S, Gutierrez D. Hystem: A Bio-absorbable Protein Delivery Polymer: Safety, and Efficacy in a Corneal Debridement Model, Rafii MJ, Wirostko B, Zarembinski t, Werner L, Mamalis N, Gum G, Pritt S. Poster Session, Systemic Blood Pressure and Ocular Perfusion Pressure Affects Blood Flow to the Optic Nerve Head in Glaucoma Patients with Diabetes, Huck aH, Harris a, Siesky Ba, tobe La, Kim nJ, amireskandari a, marek B, Januleviciene I, Wirostko BM, Eckert G. Association for Research in Vision and ophthalmology

Liliana Werner, MD, PhD

Development and Characteristics of a São Paulo, Brazil New IOL Material. 36th Simpósio Internacional Moacyr Álvaro

Speaker, Panelist, moderator, annual San Francisco, ca Meeting of the American Society of Cataract and Refractive Surgery

Poster, Light Transmittance of Seattle, WA Explanted Hydrophobic Acrylic Intraocular Lenses with Surface Light Scattering. The Association for research in Vision and ophthalmology

Development and Characteristics of Mexico City, Mexico a new Hydrophobic Acrylic IOL Material. II Curso de Actualización en Oftalmología, Sociedad Mexicana de Oftalmología

Speaker, Panelist, moderator, annual amsterdam, Meeting of the European Society of Netherlands Cataract and Refractive Surgery

Marielle P young, MD

Interpreting Letters from Pediatric Salt Lake City, UT Ophthalmologists. Utah Chapter of the Association for the Education and Rehabilitation of the Blind and Visually Impaired, Division of Services for the Blind and Visually Impaired

Diagnosis and Management of Provo, UT Infantile Cataracts. Pediatric Grand Rounds, Utah Valley Regional Hospital

Ophthalmic Findings in Pediatric Deer Valley, UT Patients who Warrant Further Work-up. Utah Ophthalmology Summer Program

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Wayne ImbrescIa John A. Moran Eye Center

claudIa s luttrell Salt Lake City, Utah

John a moran Palm Beach, Florida

randall J olson, md John A. Moran Eye Center

chase n Peterson, md Park City, Utah

lynn Ward John A. Moran Eye Center

steve Wynn Las Vegas, Nevada

norm a ZabrIskIe, md John A. Moran Eye Center

robert F bennett Falls Church, Virginia

John bloomberg La Jolla, California

reed brInton Salt Lake City, Utah

alan s crandall, md John A. Moran Eye Center

Ian cummIng Jackson Hole, Wyoming

steve deZII Las Vegas, Nevada

sPencer F eccles Salt Lake City, Utah

alan J hIrschFIeld Jackson, Wyoming

Visit our website moraneyecenter.org

John A.Moran Eye Center

65 Mario Capecchi Drive

Salt Lake City, UT 84132

801-581-2352

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FOCUS 2014 John A. Moran Eye Center University of Utah Health Care

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