2011 Session 63 - Balthazar

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    CLINICAL RESEARCH

    COLLABORATIONROUNDTABLESponsored by the Evidence-Based PracticeCommittee

    Agenda

    Overview and Introduction (15 minutes)

    Panelist Presentations (60 minutes)

    Break-out Roundtable Discussions (40 minutes)

    Closing Remarks (5 minutes)

    Objectives

    Describe several clinical research projects in Illinois

    Discuss three methods of addressing clinical researchquestions

    Identify opportunities for clinical research collaboration

    Panelists

    Catherine Balthazar, Ph.D., CCC-SLP

    Associate Professor at Governors State University

    Courses: child language development, languagedisorders, research, professional issues, and phonologicaldisorders

    Specialties: developmental language disorders, treatmentefficacy, school-age language, single subject design

    Panelists

    Jennifer Armstrong, Ph.D., CCC-SLP

    Assistant Professor at Governors State University

    Courses: Introduction/Advanced Assessment andIntervention to Communication Disorders; Early LanguageDisorders

    Specialties/Interests: Language and literacy developmentin early childhood populations; Prevention of speech andlanguage disorders; Language Development in SpecialPopulations

    Panelists

    Nicole Koonce, M.A., CCC-SLP

    Position: Research Assistant, Building ComplexSentences Project; Doctoral Candidate in SpecialEducation, University of Illinois at Chicago

    Specialties: Evidenced-based interventions for school-agechildren with language and reading disabilities, Issues inthe assessment of individuals from culturally andlinguistically diverse backgrounds; Collaborative modelsof service delivery in educational settings

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    Panelists

    Gail B. Kempster, Ph.D., CCC-SLP

    Position: Associate Professor and SLP Program Directorat Rush University

    Courses: anatomy and physiology of the speech system,research methods in CDS, voice disorders

    Specialties: voice disorders, perceptual voice analysis,research design and statistics

    Clinician-Researcher Collaboration

    Generates clinically relevant research questions

    Guides methodology of clinical studies

    Promotes adoption of research-based methods in clinicalsettings

    Connects clients to state-of-the-art treatments

    Ia

    Ib

    IIa

    IIb

    III

    IV

    LevelsofEvidence

    A Word About Levels ofEvidence

    Phases of Clinical Outcomes Research

    Phase Purpose Methods

    Phase I

    Preliminary

    The intervention and its hypothesizedeffects are identified

    Observational or correlational, estimatesof effect size

    Phase II

    Feasibility

    Clinical viability of the intervention is

    tested

    Case studies, discovery-oriented single-

    subject designs, and small group cohortcontrol studies

    Phase III

    Early Efficacy

    Begin to test efficacy Experimental, or at least quasi-experimental; test causality

    Phase IV

    Later Efficacy

    Compare target intervention with

    alternative intervention to addresscausality under more generalizableconditions

    Experimental

    Phase V

    Effectiveness

    Determining whether the therapeuticeffect is realized in day-to-day c linical

    practice

    "field research" or "community-basedresearch"

    FEATURED RESEARCHMETHODS

    Mixed Method: Adding qualitative andquantitative approaches Qualitative component is meant to:

    Gain insights into subjective issues

    Investigate a topic from a deep rather than a broad perspective

    Identify issues and opinions specific to small groups of people

    Qualitative component does not (but quantitative can): Lend itself to generalization

    Indicate a single best answer to a research question

    Generate objective numerical data which can be analyzed

    statistically

    Sources of information

    Interviews (structured, semi-structured)

    Focus groups

    Open-ended written surveys

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    Single-Subject: Measuring effects onindividuals Can help answer important clinical questions

    Does this treatment work?

    ABAB Withdrawal Multiple Baseline Across Behaviors Changing Criterion

    Which treatment is better? Alternating Treatments Design

    Which parts are effective? Interaction Design

    Particularly appropriate where the availability of a large numbers of individuals for the study of certain

    problems is limited and/or

    large physical functional variations among subjects falling into such categoriesmight confound the search for systematic treatment effects

    Validation: Relating measures toconstructs Concerned with developing measures that are

    RELIABLE

    Produce comparable results consistently

    Produce similar results among examiners

    VALID

    Scores reflect differences in target trait

    Scores reflect differences that are real

    Scores are meaningful clinically: diagnostic and prognostic value

    Quantitative methodology which requires

    Multiple types of analyses

    Large numbers of subjects

    Several phases and (usually) revisions

    LANGUAGE AND LITERACYENRICHMENT: A COLLABORATIVEAPPROACH

    Jennifer Armstrong

    Purpose/Background Information

    Purpose: Gain information about the language andliteracy knowledge of Early Childhood Educators, parents,and CDIS students in the GSU community

    Background: Early learning experiences determine futureacademic success thus it is imperative that all who are incontact with children during critical years beknowledgeable of ways to enrich language and literacyskills.

    Evidence suggests that EC educators may be limited inspecific knowledge of phonological awareness,expressive language, and general literacy skills.

    Background Information con.

    Previous study also suggests that SLPs may feel lessconfident about language and literacy knowledge as itpertains to 0-5 year olds due to limited training.

    Research Questions

    How prepared do Early Childhood Educators perceivethemselves to be in facilitating language and literacyenrichment activities in the classroom setting?

    How prepared do parents perceive themselves to be in

    facilitating language and literacy enrichment activities inthe home environment?

    How prepared do students perceive themselves to be indisseminating knowledge on the prevention ofdisorders related to language and literacydevelopment?

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    Research Design

    Mixed Method Approach

    Early Childhood Professionals and Parents

    -Twenty question survey with 6-point rating scale

    -Four open ended questions

    Students

    -Twenty question survey with 6-point rating scale

    -Reflective response

    Outcomes

    Outcomes will:

    Assist CDIS instructors in the structuring of graduatetraining programs.

    Provide an essential step in determining how best toserve this population of children

    ASSESSMENT AND TREATMENT OFGRAMMATICAL SKILLS IN OLDERCHILDREN

    Nicole Koonce

    Background Information

    The ability to produce and comprehend complexsentences is important to classroom success as childrenprogress through school

    School-age children with LI continue to struggle withgrammatical skills beyond the morphosyntax level

    Intervention research targeting syntax in older children islimited (specifically complex sentence production )

    Research Questions

    Given targeted intervention, do school-age children withlanguage impairment improve in their ability to identify,comprehend, and produce complex sentences?

    Is improvement consistent across three targeted complexsentence types?

    Is this improvement realized in norm-referenced andcriterion-referenced measures?

    Research Design

    Multiple Baseline Single Subject Design

    Baseline performance established

    Initiation of treatment results in immediate change in behavior

    Consistent demonstration of behavior change across at least two

    introductions of intervention

    BSC Project

    Pre-testing: Norm-referenced, criterion-referenced, and probe

    measures

    During treatment: Probe measures, Session data

    Post-testing: Norm-referenced, criterion-referenced, and probe

    measures

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    Assessment Measures

    Baseline1 Baseline2 Baseline3TONI3(ifneeded)

    ComplexSentences

    Probe1(Adverbials,

    ObjectComplements,

    andRelatives)

    CELF4Core

    CELF4WorkingMemory

    Subtest

    OralParaphrase Task

    ComplexSentences

    Probe2(Adverbials,

    ObjectComplements,

    andRelatives)

    GORT4

    WrittenSummarization

    Task

    ComplexSentences

    Probe3(Adverbials,

    ObjectComplements,

    andRelatives)

    TOWL3Story

    Construction

    CASLSentence

    Comprehension

    Treatment ScheduleAdverbials 1

    (time)Videotape

    Adverbials 2

    (causal,purpose)

    Adverbials 3

    (contrast)

    Adverbials 4

    (condition)

    Adverbials 5

    (concession)

    Adverbials 6

    (mixedtypes)

    1. Warm-up2. Lesson & practice

    a. ID clause (reading)b. Deconstructionc. Combining (writing)

    3. Applicationa. Clause Hunt

    4. Probe (OC, RC)

    Pre/Post-Test Measure:Written Summary

    Measures: MLTU, SI

    SALT Transcript

    If you not sleep, you will dead.

    Our brain need rest.

    If you not sleep for one day, you willbe sleepy and cranky.

    Sleep is perfect to be better atsomething.

    Its a review for the brain.

    You dream many weird thing.

    Sleep is very important for the brain.

    Its rest for the brain.

    Probe Measure:Sentence Combining /Completion

    4 - Forms one complete (complex) sentence containing the target subordinate clause (AC, RC,or OC) which is grammatically and semantically correct.

    3 - Forms one complete sentence containing the target subordinate clause which has agrammatical or semantic error

    2 - Forms one complete sentence which is grammatically correct, captures the general meaningof the two stimulus sentences, but contains a subordinate clause which is not targeted

    1 - Forms one complete sentence which is grammatically correct, captures the general meaningof the two stimulus sentences, but does not contain a subordinate clause (i.e., it is a simplesentence) OR Forms 2 coordinated clauses

    0 - Does not form a complete sentence or repeats the two stimulus sentences or sentence issemantically untenable.

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    Research-Practitioner Connections

    Research situated in the context in which children receiveservices

    Allows children access to new treatment approaches

    Provides professional development to SLPs

    Encourages research and application in educationalsettings

    DEVELOPMENT ANDVALIDATION OF THE CONSENSUS

    AUDITORY PERCEPTUALEVALUATION OF VOICE (CAPE-V)

    Gail B. Kempster

    Background to the CAPE-V

    CAPE-V is a protocol to follow and form to use whenassessing perceived voice quality.

    Arose from a 2002 international consensus conferencewhich brought together scientists, researchers, andclinicians

    CAPE-V drafted in 2002, disseminated (beta form) forreview, use, and feedback via D3 website

    Official protocol and form published in May 2009 in AJSLP

    Elements to the CAPE-V Protocol

    Listen to voice in 3 contexts

    Sustained /a/ and /i/

    6 specified sentences

    Conversation

    Evaluate voice for overall severity, roughness,breathiness, strain, pitch, and loudness

    Other elements may be assessed

    Measures taken on 100 mm line, with left end designatednormal or none

    CAPE-V Protocol Validating an Instrument

    Reliability: degree to which judgments on the scale aredependable or consistent within a rater or across raterson repeated administrations.

    Validity: extent to which a scales scores can beinterpreted as representative of a particular underlyingconstruct.

    content, face, construct, criterion, empirical, convergent, predictive

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    Establishing Validity

    Sechrest (2005):

    The crux of the matter lies in Messicks assertion thatValidity is not a property of the test or assessment assuch, but rather of the meaningof the test scores. It isnot measures that are valid, but the scores that they yieldand the interpretation we make of them.

    Establishing Validity

    Empirical validity (aka concurrent validity) compares anew instrument with another instrument that in theorymeasures the same construct.

    Is one step in the process of establishing the constructvalidity of a new scale.

    How to validate the CAPE-V?

    Study supported by Div 3 (R. Zraick, PI)

    59 voices judged a priori as normal, mild, moderate, orsevere by panel of three slps

    21 experienced voice clinicians across the US

    Voices judged on CAPE-V and GRBAS scales

    GRBAS most common tool used world-wide

    Data analyzed for reliability and empirical validity

    CAPE-V Reliability and Validity

    Zraick, et al. 2010 published online in AJSLP

    CAPE-V ratings correlated highly with GRBAS

    All > .76

    Specifically, for the CAPE-V

    Mean intra-rater reliability ranged from .35 (Strain) to .82(Breathiness)

    Mean inter-rater reliability ranged from .28 (Pitch) to .76(Overall Severity)

    Next Steps

    Does training of judges help?

    Should anchor voices be used?

    Is there benefit to judging the 3 speech productions askedfor in the protocol?

    Are the scores obtained clinically meaningful?

    Roundtable Discussions

    Panelists and members of the EBP committee are atdesignated tables

    Join a tableExchange research ideas, get help developingideas into researchable questions, explore methods that

    would be appropriate for answering clinical questions,share experiences

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    Thank You for Participating

    Fill out quick survey at back of handout and return to oneof the panelists

    Future contacts encouraged

    Catherine Balthazar c-ba [email protected]

    Jessica Bonner [email protected]

    Stephanie Hughes [email protected]

    Ravi Nigam [email protected]