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Figure – Supplemental Digital Content 1 - This figure demonstrates the log FT and SHBG by HIV status and age. FT was higher in HIV-uninfected individuals and decreased with age. The FT in an HIV-infected man was equivalent to the FT in an HIV-uninfected man 13 years older (β HIV-infected v. uninfected status: -0.13 (p < 0.001); β age: -0.01 (p < 0.0001)). SHBG was lower in HIV-uninfected individuals and increased with age. The SHBG in an HIV-infected man was equivalent to the SHBG in an HIV-uninfected man 20 years older (β HIV-infected v. uninfected status: 0.20 (p < 0.0001); β age: 0.01 (p < 0.0001)).