20101105 Tradeline Animal Facilities 2010.ppt

Animal Research Facilities 2010Tradeline Conference Series

NEW CAGEWASH DECISIONS NEW CAGEWASH DECISIONS FOR RAISING EFFICIENCY,

LOWERING OPERATING COSTS, AND CUTTING LABOR

Concurrent Forum Session “G”

November 08 & 09 2010November 08 & 09 2010

Lloyd E.L. Fisk, AIA LEED APPaul Lemestre, PE LEED AP

Research Facilities Design

PRESENTATION OUTLINE

I. Introduction

II Cagewash Metric AnalysesII. Cagewash Metric Analyses

III. Cagewash Layout Issues

IV. MEP System Issues

V. Conclusions

Please ask questions as you think of them


I. Introduction




V. Conclusions


II. CAGEWASH METRIC ANALYSIS

• Department of Veterans Affairs Denver Medical Center• Linus Pauling Institute at Oregon State

Case Study Facilities

• Max Planck Florida Institute • Scripps Research Institute Florida • South Australia Health and Medical Research Institute• University of Nebraska Medical Center Durham Research Center• University of Nevada Reno Center for Molecular Medicine • University of Southern California Zilkha Neurogenetic Institute • University of Texas, Austin Norman Hackerman Building• University of Texas Austin Dell Pediatric Research Institute• University of Texas, Austin Dell Pediatric Research Institute • University of Texas MD Anderson Cancer Center South Campus Vivarium • Washington State University Biotechnology Building


Case Study Facilities – Completion Year

4

1

2

3

0

2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013


Case Study Facilities – Overall Vivarium Size (NSF)

60000

20000

30000

40000

50000

0

10000

1 2 3 4 5 6 7 8 9 10 11 12


Case Study Facilities – Vivarium Cage Capacity

35000

10000

15000

20000

25000

30000

0

5000

1 2 3 4 5 6 7 8 9 10 11 12


Cagewash as a % of Overall Vivarium NSF



25%

10%

15%

20%

0%

5%

1 2 3 4 5 6 7 8 9 10 11 12



25%60000

5%

10%

15%

20%

20000

30000

40000

50000

Total Vivarium NSF

Cagewash % of Facility

0%

5%

0

10000

1 2 3 4 5 6 7 8 9 10 11 12



25%60000

10%

15%

20%

20000

30000

40000

50000

Total Vivarium NSF


Linear (Cagewash % of Facility)

0%

5%

0

10000

1 2 3 4 5 6 7 8 9 10 11 12


Holding Capacity (Cages)/ NSF of Cagewash Suite



14.00

6.00

8.00

10.00

12.00

5.32

0.00

2.00

4.00

1 2 3 4 5 6 7 8 9 10 11 12



14.00

6.00

8.00

10.00

12.00

4.64

0.00

2.00

4.00

1 2 3 4 5 6 7 8 9 10 11 12


Holding Room NSF/ NSF of Cagewash Suite


Holding Room NSF/ NSF of Cagewash Suite

3 00

3.50

1.50

2.00

2.50

3.00

1.69

0.00

0.50

1.00

1 2 3 4 5 6 7 8 9 10 11 12


Dirty Cagewash/ Clean Cagewash


Clean Cagewash/ Dirty Cagewash

1.60

1.80

1.08

0.60

0.80

1.00

1.20

1.40

1.60

0.00

0.20

0.40

1 2 3 4 5 6 7 8 9 10 11 12


Disposable Caging Option


Disposable Caging Option

6,500 Cage Capacity

Change @ 14 Days

3,250 Cages/ Week

14,000 Cages/ Month

= 14 Clean Pallets of Storage

+ 14 Dirty Pallets of Storage

+ Handling/ Maneuvering Space

= 1,300 NSF of Cage Handling Space


Disposable Caging Option – Cagewash as a % of Overall Vivarium

25%60000

10%

15%

20%

20000

30000

40000

50000

Total Vivarium NSF



0%

5%

0

10000

1 2 3 4 5 6 7 8 9 10 11 12



25%60000

10%

15%

20%

20000

30000

40000

50000

Total Vivarium NSF



0%

5%

0

10000

1 2 3 4 5 6 7 8 9 10 11 12



25%60000

10%

15%

20%

20000

30000

40000

50000

Total Vivarium NSF


Linear (Cagewash % of Facility)9%

0%

5%

0

10000

1 2 3 4 5 6 7 8 9 10 11 12



25%60000

10%

15%

20%

20000

30000

40000

50000

Total Vivarium NSF


Linear (Cagewash % of Facility)9%

0%

5%

0

10000

1 2 3 4 5 6 7 8 9 10 11 12?


Metrics Summary

Cagewash as a % of Facility NSF: 12-18%

H ldi C it (C )/NSF C h 2 6 CHolding Capacity (Cages)/NSF Cagewash 2-6 Cages

Holding Room NSF/ NSF Cagewash 1:1 to 2.5:1

Clean Cagewash/ Dirty Cagewash 0.7:1 to 1.5:1


I. Introduction




V. Conclusions


III. CAGEWASH LAYOUT ISSUES

Cagewash Rooms

Contaminated

Dirty

Clean

Sterile Sterile

Project 1 2 3 4 5 6 7 8 9 10 11 12


Cagewash Rooms – Autoclave Location




Cagewash Chambers


Cagewash Chambers


Cagewash Chambers


Cagewash Chambers


Barrier Walls


Barrier Walls


Barrier Walls


Barrier Walls


Drainage


Drainage


Drainage


Automation


Automation


Automation

Robotics

Bedding Removal

Bedding Delivery

Project 1 2 3 4 5 6 7 8 9 10 11 12Project 1 2 3 4 5 6 7 8 9 10 11 12

Garbell


Detergent Handling


Detergent Handling


Detergent Handling


Detergent Handling


Utility Drops


Utility Drops


Utility Drops


Utility Drops


I. Introduction




V. Conclusions


CAGEWASH MEP SERVICES (SUMMARY)

HVAC• General Exhaust• Equipment Exhaust• Supply Air

ELECTRICAL• 480 vac/3ɸ• 208 vac/3ɸ

120 /1ɸSupply Air

PLUMBING• Steam• Steam Condensate Return• Industrial Cold Water (non-potable)• Industrial Hot Water (non-potable)

• 120 vac/1ɸ

( p )• Compressed Air• Sanitary Drainage• Animal Water

CAGEWASH MEP SERVICES – EQUIPMENT DRAINAGE

MEDIUM STERILIZER• Equipment floor sink

BULK STERILIZERBULK STERILIZER• Recessed Pit Mounted• Pit drainage/equipment drainage

CAGE/RACK WASHER• Recessed Pit Mounted• Pit drainage/equipment drainageg / q p g• Pre-wash drainage• Post-wash drip drainage

TUNNEL WASHER• Multiple equipment drainage locations


Tunnel Washer Drains

Pre-Wash Drain Grate


Post-Wash Drain Grate

Tunnel Washer Drains

Pit/Equipment Drain

CAGEWASH HEAT LOADS – EXAMPLE

CAGEWASH DIRTY• Area: 1,000 SF• Equipment Heat Load: 27,000 Btuh• 6 ACH Ventilation: 1,000 cfm


CAGEWASH EQUIPMENT•Area: 450 SF•Equipment Heat Load: 133,000 Btuh •6 ACH Ventilation: 450 cfm


CAGEWASH CLEAN• Area: 1,100 SF• Equipment Heat Load: 48,000 Btuh• 6 ACH Ventilation: 1,100 cfm

CAGEWASH HEAT LOADS (75F room temperature all areas)

ROOM AREA HEAT LOAD EQUIPEXHAUST

6 ACH AIRFLOW

DESIGNAIRFLOW

DESIGNACH

CagewashDirty

1,000 SF 27,000 Btuh 0 cfm 1,000 cfm 1,270 cfm 7.6y

Cagewash Equip

450 SF 133,000 Btuh 2,200 cfm 450 cfm 6,160 cfm 82.1

Cagewash Clean

1,100 SF 48,000 Btuh 0 cfm 1,100 cfm 2,250 cfm 12.2

Notes: Based on 10-ft ceiling height; 75F design room temperature

CAGEWASH HEAT LOADS (75F Room; 85F Equip)

ROOM AREA HEAT LOAD EQUIPEXHAUST

6 ACH AIRFLOW

DESIGNAIRFLOW

DESIGNACH

CagewashDirty

1,000 SF 27,000 Btuh 0 cfm 1,000 cfm 1,270 cfm 7.6y

Cagewash Equip

450 SF 133,000 Btuh 2,200 cfm 450 cfm 4,800cfm 64

Cagewash Clean

1,100 SF 48,000 Btuh 0 cfm 1,100 cfm 2,250 cfm 12.2

Notes: Based on 10-ft ceiling height; 75F design room temperature Dirty and Clean; 85F design temperature Equip.

CAGEWASH HEAT LOADS - CANOPIES

• Heat & vapor capture• Promotes heat removal from

equipment – reduce ACH rates and HVAC energyW k f t• Worker comfort

CAGEWASH EQUIPMENT – ENERGY SAVINGS INITIATIVES

• Water use reduction• Equipment heat load reduction – HVAC energy reduction• Energy recovery• Waste water recoveryWaste water recovery• Increased productivity (fewer cycles)• VHP decontamination


• Water use reduction

• Autoclave water saving package (recirculating closed water loop)• Example:

• 227 gal/cycle standard• 68 gal/cycle with water saving package• 70% reduction• 0.232 Kw-Hr vs 0.772 Kw-Hr (230% increase)

• Autoclave vacuum pump versus water air ejector• Tradeoff between water consumption and electrical• Tradeoff between water consumption and electrical

consumption• Drain cooldown heat exchanger

• Utilize house closed water cooling system (chilled or process) to temper drain water below 140°F.

• Example:• Cage/rack washer: reduce water consumption by

696,800 gal/year (20 cycles per day)


•Water use reduction (continued)

•Washer rinse recovery re-use tank•Capture and store final rinse water for next cycle pre-wash

•Washer low volume sumps•Reduce fill volume of water for cycles•Example:

•50% water reduction on equipment startup•18% water reduction during continuous operation


• Water use reduction• Equipment heat load reduction – HVAC energy reduction

• Sealed doors• Reduced equipment heat loss from hot water and drying

• High efficiency insulation• Reduce heat loss to surrounding room – reduces HVAC energy


• Water use reduction• Equipment heat load reduction – HVAC energy reduction• Energy recovery

• Air-to-air exhaust heat exchangers (Cage/Rack washers)• Pre-heat incoming air during drying phase• Reduce temperature and humidity of equipment

exhaust – less corrosion on exhaust system• Reduced drying time – chamber reaches

temperature more quickly• Achieve higher chamber temperature for drying

Exhaust from

chamber

Achieve higher chamber temperature for drying• Example:

• 180°F vs 150°F• Reduced steam load of 17.2 lbm/cycle

(90,000 lbm/year)• Example:

• 33% energy reduction/cycle Building Exhaust

Dryingair to

chamber

Room Air


• Water use reduction• Equipment heat load reduction – HVAC energy reduction• Energy recovery• Waste water recoveryWaste water recovery

• Collect equipment waste water and route to building reclaimed water system• Reclaimed water system used for

• Irrigation• Cooling tower make-up water• Restroom flushing water


• Water use reduction• Equipment heat load reduction – HVAC energy reduction• Energy recovery• Waste water recoveryWaste water recovery• Increased productivity (fewer cycles)

• Increased load capacity• Spray manifold design• Equipment width and wash rack design• Example:p

• 184 cages/cycle vs 92 cages/cycle• Improved drying effectiveness and controls

• Turbulent drying air• Relative humidity sensing to end drying cycle


• Water use reduction• Equipment heat load reduction – HVAC energy reduction• Energy recovery• Waste water recoveryWaste water recovery• Increased productivity (fewer cycles)• VHP decontamination

• Cage/rack washer• Duel use:

• Cage/rack wash (traditional)g / ( )• VHP decontamination

• Space savings• Potential for reduce bulk autoclave cycles – reduced utilities

• Thermal disinfection (autoclave) vs chemical disinfection (VHP)

CAGEWASH EQUIPMENT – ITEMS TO WATCH OUT FOR

CONDENSATE RETURN EQUIPMENT• No space allocated for additional MEP equipment in Cagewash areas.• Large equipment• Locate in separate room or mezzanine above

CAGEWASH EQUIPMENT – ITEMS TO WATCH OUT FOR

EQUIPMENT DRAINAGE• Plumbing drains magically appear from above!• Some equipment drainage is located specifically for the equipment only.

Should not be used for HVAC drains.• Be detailed in design for drainage of non-Cagewash equipment and systems


I. Introduction




V. Conclusions


V. CONCLUSIONS – THE TRADELINE THREE

1. PLAN FOR ADEQUATE BUT NOT EXCESSIVE CAGEWASH SPACE

2. DISCUSS THE DETAILS!2. DISCUSS THE DETAILS!

3. LOOK FOR ENERGY SAVINGS WHEREVER POSSIBLE

Animal Research Facilities 2010Tradeline Conference Series

NEW CAGEWASH DECISIONS NEW CAGEWASH DECISIONS FOR RAISING EFFICIENCY,

LOWERING OPERATING COSTS, AND CUTTING LABOR

Concurrent Forum Session “G”

November 08 & 09 2010November 08 & 09 2010

Lloyd E.L. Fisk, AIA LEED APPaul Lemestre, PE LEED AP

Research Facilities Design

20101105 Tradeline Animal Facilities 2010.ppt

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