2009 12 07 - LOINC Introduction and Overview

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LOINC® Overview and Introduction 12.07.2009 Daniel J. Vreeman, PT, DPT, MSc Assistant Research Professor | Indiana University School of Medicine Research Scientist | Regenstrief Institute, Inc Copyright © 2009 Laboratory LOINC Workshop

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Transcript of 2009 12 07 - LOINC Introduction and Overview

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LOINC®  Overview  and  Introduction  

12.07.2009  

Daniel  J.  Vreeman,  PT,  DPT,  MSc  Assistant  Research  Professor  |  Indiana  University  School  of  Medicine  

Research  Scientist  |  Regenstrief  Institute,  Inc  

Copyright  ©  2009  

Laboratory  LOINC  Workshop  

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Overview  • Origins  of  LOINC  – Background  – Growth  – Participation  

• Successes  –  International  – US  

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Origins  of  LOINC  The  Lingua  Franca  of  Clinical  

Observation  Exchange  

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•  Regenstrief’s  30-­‐year  history  •  The  Indiana  Network  for  Patient  Care    

–  A  working  HIE  for  ~15  years  –  More  than  100  sources  –  Regenstrief:  3rd  party  convener  

•  Local  systems  use  idiosyncratic  codes  

*Smith  CP,  Araya-­‐Guerra  R,  Bublitz  C,  et  al.  Missing  clinical  information  during  primary  care  visits.  JAMA.  2005;293(5):565-­‐571  

Introduction  

•  Vocabulary  standards  –  LOINC  ®    -­‐  universal  code  system  for  clinical  observations  –  The  lingua  franca  of  information  exchange  

•  Laboratory  and  Radiology  results*    –  Often  unavailable  at  the  time  of  a  clinical  visit  (6%,  4%)  –  Often  located  outside  of  their  clinical  system  

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Indiana  Network  for  Patient  Care  

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From  whence  comes  LOINC?  • LOINC®  –  Logical  Observation  Identiiiers  Names  and  Codes  – A  universal  code  system  for  laboratory  and  other  clinical  observations  

– The  lingua  franca  of  information  exchange  for  clinical  observations  

McDonald  CJ,  Huff  SM,  Suico  JG,  et  al.  LOINC,  a  universal  standard  for  identifying  laboratory  observations:  a  5-­‐year  update.  Clin  Chem.  2003;49(4):624-­‐633.  

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Indiana Network for Patient Care

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MSH|^~\&|HOSPITAL_A|SAMPLE_HOSPITAL_A|||$YearMonthDay||||||||||||||| PID|||$patientId$||$patientName$|||||||||||||||||||| PV1|||||||$attendingDoctor$||$consultingDoctor$|||||||| OBR|1|||CBC^CBC/Auto Diff^HSPA^57021-8^CBC W Auto Diff^LN||$reqDate||||||||| OBX|2|ST|WBC^WBC^HSP_A^26464-8^Leukocytes [#/volume] in Blood^LN||10.8|K/MM3|||||F| OBX|3|ST|RBC^RBC^HSP_A^26453-1^Erythrocytes [#/volume] in Blood^LN||4.82|MIL/MM3|||||F| OBX|4|ST|HGB^HGB^HSP_A^718-7^Hemoglobin [Mass/?volume] in Blood^LN||15.7|GM/DL|||||F| OBX|5|CE|HCT^HCT^HSP_A^20570-8^Hematocrit [Volume Fraction] of Blood^LN||45|%|||||||F|

HL7 v.2.X Message

LocalCode^LocalName^CodeSystem^LOINCcode^LOINCname^CodeSystem

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LOINC  Purpose  

•  Speciiically,  to  provide  a  universal  ID  for  the  OBX-­‐3  iield  in  HL7  ORU  messages  

•  LOINC  codes  “questions”,  not  answers  – Orders/Panels  (OBR-­‐4)  – Questions  (OBX-­‐3)  – NOT  Values  (OBX-­‐5)  • Numbers,  organisms  (E.  coli)  

To  facilitate  the  exchange  and  pooling  of  results  for  clinical  care,  outcomes  management,  and  research  

McDonald  CJ,  Huff  SM,  Suico  JG,  et  al.  LOINC,  a  universal  standard  for  identifying  laboratory  observations:  a  5-­‐year  update.  Clin  Chem.  2003;49(4):624-­‐633.  

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•  If  an  observation  is  a  question,  and  the  observation  value  an  answer:  –  LOINC  provides  codes  for  the  questions  {OBR-­4,  OBX-­3}  –  Other  systems  (eg  SNOMED)  provide  codes  for  the  answers  

718-­‐7:Hemoglobin:MCnc:Pt:Bld:Qn  

What  is  my  patient’s  hemoglobin  level?  

LOINC’s  General  Role  

41959-­‐8:Walking  speed:Vel:1W^mean:^Patient:Qn:Calculated  

How  fast  does  my  patient  usually  walk?  

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LOINC  Background  •  Organized  by  Regenstrief  Institute  in  1994  

–  Ongoing  support  from  NLM  and  Regenstrief  –  Guided  by  the  LOINC  Committee  (Lab  +  Clinical)  

•  Covers  domain  of  Clinical  Observations  –  Laboratory  observations  (since  1995)  –  Clinical  observations  (since  1996)  –  HIPAA  Claims  Attachments  (NPRM  in  2005)  

•  LOINC  development  is  a  highly  ‘open  source’  model  –  Open,  nimble,  pragmatic  –  LOINC  and  RELMA  program  are  freely  available  –  Much  work  is  done  by  volunteers  –  Additions  to  the  database  are  end-­‐user  driven  

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LOINC  Submissions  2003-­2008  

67  Organizations,  13  Countries  

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Active  Translation  Efforts  

16  Countries  

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Laboratory  LOINC  ― Chemistry   ― Allergy  Testing  ― Urinalysis   ― Blood  Bank  ― Toxicology   ― Cell  Markers  ― Hematology   ― Skin  Tests  ― Microbiology   ― Coagulation  ― Antibiotic  Susceptibilities   ― Cytology  ― Immunology/Serology   ― HLA  Antigens  ― Molecular  Genetics   ― Surgical  Pathology  ― Cell  Counts  

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Clinical  LOINC  ― Vital  Signs   ― EKG  

― Hemodynamic  Measurements   ― Cardiac  Ultrasound  

― Fluid  Intake/Output   ― Obstetrical  Ultrasound  

― Body  Measurements   ― Discharge  Summary  

― Emergency  Department  Variables     ― History  and  Physical  

― Respiratory  Therapy   ― Pathology  Findings  

― Tumor  Registry   ― Colonoscopy/Endoscopy  

― Patient  Assessment  Instruments   ― Clinical  Documents  

― Ophthalmology  Measurements   ― Document  Sections  

― Radiology  Reports   ― Patient  Assessment  Instruments  

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Slope = 600

Slope = 2200

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Downloads:    875/month  

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~  80  Organizations  Listed  

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3,121  email  addresses    

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Current  Initiatives/Successes  

International  and  US  Adoption  

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International  Adoption  

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Existing  Translations  •  Spanish  

–  BiTAC  (Spain);  39,000  terms    –  Conceptum  Medical  Terminology  Center;  38,000  terms,  Users’  Guide  –  Mexican  Institute  of  Social  Security;  Users’  Guide  

•  French  –  Canada  Health  Infoway;  38,000  terms,  Documentation  –  Société  Française  d'Informatique  de  Laboratoires;  4,000  terms  

•  Simpliiied  Chinese  –  Bethune  International  Peace  Hospital;  38,000  terms,  Users’  Guide,  tutorial  

•  Korean  –  Korean  Ministry  for  Health,  Welfare  and  Family  Affairs;  27,000  terms  

•  German  –  DIMDI;  Companion  website,  Users’  Guide  

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New  Translations  (this  release)  

•  Estonian  –  Estonian  LOINC  working  group  of  the  Estonian  Society  for  Clinical  Chemistry;  Users’  Guide,  Tutorial  

•  Portuguese  –  Brazilian  Federal  Agency  for  Health  Plans  and  Insurance,  Brazilian  Clinical  Analysis  Society,  Brazilian  Clinical  Pathology  Society,  and  Diagnóstico  das  Américas  (DASA);  2,800  terms  

•  German,  French,  Italian,  Spanish  –  CUMUL  (Switzerland);  5000  common  terms  

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In-­‐progress  Translations  •  French  

–  Assistance  Publique-­‐Paris  Hospitals  (PMID:  18999107)  

•  Estonian  –  University  of  Tartu;  Lab  terms  

•  Dutch  –  SKML  (the  Dutch  Foundation  for  Quality  Assessment  in  Medical  Laboratories);  Lab  terms  

•  Catalan  –  BiTAC;  Lab  terms  

•  Russian  –  Donetsk  National  Medical  University,  corTTex  

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How  do  you  say  “glucose?”  Component   Linguistic  Variant  Glukose   German  (Switzerland)  Glucose   French  (Switzerland)  Glucosio   Italian  (Switzerland)  Glucosa   Spanish  (Switzerland)  葡萄糖   Simpliiied  Chinese  (China)  Glucosa   Spanish  (Argentina)  Glükoos   Estonian  (Estonia)  Glicose   Portuguese  (Brazil)  -­‐  Draft  Glucosa   Spanish  (Spain)  포도당   Korean  (Korea,  South)  

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New  Translation  Approach  •  Prior  Method  – Translate  whole  name  as  one  string  

•  New  Method  – Break  LOINC  terms  into  their  constituent  Parts  – Remove  duplicate  strings  in  Part  list  – Translate  the  Part  strings  – Reassemble  the  full  LOINC  name  

•  Beneiits  – Reduced  translation  work  – Enables  multilingual  searches  in  RELMA  

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US  Adoption  a  few  recent  highlights  

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Consolidated  Health  Informatics  Initiative  

• CHI  Goal:  – Adopting  interoperability  standards  to  enable  all  agencies  in  the  federal  health  enterprise  to  “speak  the  same  language”  

•  In  2006,  adopted  LOINC  as  standard:  –  Laboratory  test  order  names  – Medications:  Structured  Product  Labeling  Sections    

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Consolidated  Health  Informatics  Initiative  

•  In  2007,  CHI  adopted  LOINC  as  standard  for  federally-­‐required  assessments:  – questions  and  answers  – assessment  forms  that  include  functioning  and  disability  content  

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Other  Key  US  Adoptions  •  UMLS  •  VA  •  CDC  PHIN  Initiatives  

–  Implement  CHI  standards  

•  IHS  –  Embarking  on  ~250  facility  mapping  process  

•  NCQA/HEDIS  –  Healthcare  Effectiveness  Data  and  Information  Set  –  Used  90%  of  health  plans  to  measure  quality  

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Other  Key  US  Adoptions  •  ARRA  “Meaningful  Use”  •  HITSP  

–  C80:  vital  signs,  lab  results,  lab  orders,  genetic  results,  other  results  –  IS92:  newborn  screening  

•  eLINCS  –  Standard  for  results  delivery  from  LIS  to  an  EHR  

•  NAACCR  •  CDISC  

–  Pharmaceutical  research  specs  •  NCI  –  caBIG  

–  Lab  portion  adopted  as  caBIG  vocab  standard  

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Other  Key  US  Adoptions  •  HL7  –  many  implementation  guides,  CDA,  etc  •  HIPAA  Claims  Attachments  •  Many  Regional  HIEs