2006WIL Research Laboratories, LLC 1 Unit One – Introduction to Laboratory Animal Care.
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Transcript of 2006WIL Research Laboratories, LLC 1 Unit One – Introduction to Laboratory Animal Care.
2006 WIL Research Laboratories, LLC
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Unit OneUnit One
– – Introduction to Laboratory Introduction to Laboratory Animal CareAnimal Care
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Chapter oneThe Field of Laboratory Animal Science
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Laboratory Animal Science Care of laboratory animals husbandry nutrition behavior health production management
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Laboratory Medicine diagnosis, treatment and prevention of
laboratory animal disease veterinary specialty
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Role of Technician eyes, ears, hands of the
team that provides information from the animals to the investigator.
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Laboratory Animal Science recognized field in late 1940’s animals used in experimentation
Aristotle 2nd century Rome advances into early 20th century
1915- Simon Brimhall (first laboratory animal veterinarian)
1950’s- humane awareness of animals in research, more government funding, public concern
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Animal Care Panel Group of Veterinarians Lead by Dr. Nathan Brewer 1950 Goal to create a national organization
professionally concerned with the production , care, and study of laboratory animals.
Animal Care Panel Basic philosophy: Those who use animals for
research have a moral obligation to provide for their needs and ensure their welfare.
Defined good husbandry practices Defined medical care needs became American Association for Laboratory
Animal Science (AALAS) in 1967
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AALAS
National organization dedicated to the humane care and treatment of lab animals
two journals Journal of AALAS Comparative Medicine
certifies technicians promotes education Annual meetings
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Other Associations AAALAC
Association for the Assessment and Accreditation of Laboratory Animal Care, International
Formed in 1965 voluntary site evaluations and accreditation high standards WIL is accredited
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Other Associations National Association for Biomedical
Research (NABR) Incurably Ill for Animal Research (iiFAR)
American Veterinary Medical Association (AVMA) 2000 Report of the AVMA Panel on Euthanasia veterinarians
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More…... American College of Laboratory Animal
Medicine (ACLAM) board certified veterinarians (called
Diplomats) Specialize in Lab animal medicine,
completion of examination, etc.
Animal Models Similar processes
Nervous system development – zebrafish Brain development – monkeys Heart – pig
Many medical and surgical advances
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Differing views People for the Ethical Treatment of Animals
(PETA) Stop Huntington Animal Cruelty USA
opposed to the use of animals in research Distribute pamphlets demonstrations
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Principle investigator/study director Co-investigators and Research Technicians Technicians Veterinarian Commercial vendors
Research team
Principal Investigator PI, Study director Plans and coordinates all phases of the
research work Develops the Protocol Reports findings
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Co-investigators and Research technicians
Observing the experimental animals Performing laboratory tests Collect, organize, and analyze the data Can be animal technicians
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Laboratory Animal Veterinarians Coordinate animal care activities Advises investigators on proper animal model
selection Overall maintenance of animal colony health Assure compliance with various regulations
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Laboratory Animal Technicians
reduce variables environment, handling, etc
provide consistent and thorough animal care first to recognize and report potential animal
problems should have general knowledge of regulations
concerning animal use in research
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Roles continued... keep accurate records
accurate, legible Willing to learn about the animals in their
care Follow SOPs always ask if in DOUBT!
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Certifications Through AALAS Assistant Laboratory Animal Technician
(ALAT) Laboratory Animal Technician (LAT) Laboratory Animal Technologist (LATG)
ALATs should be able to: Handle routine husbandry tasks – watering,
feeding, bedding changes Perform sterilization and sanitation
procedures Observe and report environmental changes Handle, restrain, and determine sex of
common lab animals
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Cont' Use a variety of methods of animal
identification Recordkeeping Recognize common signs of illness, note
changes in eating, behavior, stool or urine Provide routine treatments, such as
administering medications or clipping overgrown toenails
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