DOWN SYNDROME

khalili amin dmd

Definition

Down syndrome (DS) or Down's syndrome, also known as trisomy 21, is a chromosomal condition

caused by the presence of all or part of a third copy of chromosome 21. Down syndrome is the most common

chromosome abnormality in humans.

Sign and symptoms

A small head compared to body sizeBroad feet with short toesEars that are small and set lowShort arms and legs compared to length of bodyBroad hands with short fingers and a single crease across the palmSmall nose and small mouth, in which the tongue may be relatively largeLack of muscle toneAbility to extend body joints; extreme flexibilityEyes that slant upward and outward.

Dental correlation

poor dental health and acute neurological disease were associated with the severity of intellectual disability and ageing.