1/8 Performance Materials Our innovative pharmaceutical ... · Horphag Research, Switzerland...

Innovative ingredientsfor the nutraceuticals industry

Business Unit

Performance Materials

Think Asia. Think DKSH.

Business LinePharmaceutical IndustryIndia

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Our innovative personal care and cosmetics portfolio

Maxilact: • Low lactose or lactose free milk

Our innovative portfoliopharmaceutical

Our Indian sales offices• Ahmedabad• Bangalore• Chennai• Delhi• Hyderabad• Kolkata • Mumbai

Our core competences

Freund Corporation, Japan

Products Generic name Characteristics Application

Dilactose RDilactose FDilactose S

Lactose Monohydrate (Granulated)

Grade differentiation based on particle size

Used in direct compression formula-tions to provide good flow and sup-erior compressibility. Tablets manu-factured with Dilactose provides quick disintegration

The information contained in this brochure and the various products described are intended for use only by persons having technical skills and at their own discretion and risk. Certain end uses of these products may be regulated pursuant to rules or regulations governing medical devices, drug uses, or pesticidal or antimicrobial uses. It is the end user’s responsibility to determine the applicability of such regulations to its products.

Pharmaceutical industry Branch locations

NOF CORPORATION

Products Generic name Characteristics Applications

Kimica Algin ULV-5G Sodium alginate High stiffness gelation type sodi-um alginate

Used in controlled release formula-tionsGastric reflux prevention

Kimica Algin IL-6G Wound dressing

Kimiloid LVCKimiloid HVC

Propylene glycolalginate

Standard type propylene glycol alginate

Used as a suspending agent, emulsion stabilizer, plasticiser and binder

Kimiloid ABKimiloid LLVKimiloid NLS-KKimiloid LVKimiloid MVKimiloid HV

High esterification type propy-lene glycol alginate

Kimica Algin K Potassium alginate – Dental impression material

Kimica Algin Ca Calcium alginate Gelling agent

Kimica Algin NH Ammonium alginate Dental impression material

Kimica Algin Mag Magnesium alginate Anti reflux suspensions for infants

Clariant, Switzerland


Polyglykol 300Polyglykol 400Polyglykol 600

Polyethylene glycols/ Macrogols

Brand name followed by num-bers indicate the average mole-cular weight

The high solvent power leads to a broad use of low molecular weight PEGs in liquid preparations such as drops, parenterals or fillings for gelatin capsules

Polyglykol 1000 Polyethylene glycols/ Macrogols

– Used to make ointment base

Lanogen 1500 Polyethylene glycols/ Macrogols

Ointment base (JP) containing Polyglykol® 300 and 1500 in a ratio of 1:1.

Used as an ointment base


Polyglykol 1500 SPolyglykol 2000 SPolyglykol 3000 S/PPolyglykol 3350 S/P/PSPolyglykol 4000 S/P/PF/ PSPolyglykol 6000 S/P/PFPolyglykol 8000 S/P/PFPolyglykol 10000 S/PPolyglykol 12000 S/PPolyglykol 20000 S/PPolyglykol 35000 S


Brand name followed by num-bers indicate the average mole-cular weight‘S' stands for flakes'P' stands for powder'PF' stands for fine powder'PS' stands for spray dried powder

• Solid PEGs are preferred bases for suppository masses. PEGs can be used as carriers, solubilizers and absorption improvers for active substances, usually processed in the form of a melt (melt granu- lation)• They also act as lubricants and binders during tablet processing• PEGs also has a plasticizing effect which facilitates the shaping of the tablet mass in the compression process and may counteract capping• Solid PEGs are also frequently used in tablet coatings as a plasticizer. The flexibility of sugar-coated tablets is increased by PEGsThe USP/NF describes a blend in the monograph ‘PEG 3350 and Electrolytes for Oral Solution’ as a laxative preparations which con-tains a detailed description of all potential individual salt compo-nents to be used in addition to the polyglycol with a mean molecular weight of 3350

Products

Cavamax W8 - CoQ10 complex

Cavacurcumin: Cavamax W8 Curcumin

HTEssence

L-Cysteine

Cavamax W6 Food


DKSH Group• Leading provider of Market Expansion Services• Total Sales CHF 11.3 billion (2018)• 33,000 employees in 35 markets• More than 150 years in Asia

Business Unit Performance Materials• We source, develop, market and distribute a wide range of specialty chemicals and ingredients• Focus on industries and applications• Over 1,080 specialized staff in 31 markets• 17 sourcing offices worldwide• 100 business locations

Business Lines• Food & Beverage Industry• Personal Care Industry• Pharmaceutical Industry• Specialty Chemicals Industry

Your preferred partner for sourcing• Comprehensive sourcing network in Asia, Europe and the Americas• Proven track record• Early trend scout• Global technology transfers• Highly dedicated team of sourcing specialists

Our key sourcing offices• China• Europe• India• Japan• Korea

DKSH – ideal partner for Pharmaceutical IndustryWe supply a wide range of innovative, high-performance excipients, interme-diates, solvents, key raw materials, actives for the pharmaceutical and nutraceutical industry. To ensure the long-term success of our business partners, we constantly deliver solutions that give them a compe-titive advantage. We provide, regulatory

support, technical assistance, logistics, warehousing, distribution and periodic market intelligence amongst a range of value added services.

Proven operational efficiencyWe continuously improve the efficiency of our processes. The quality of our services is based on best practices and standards throughout our entire organization. An

efficient supply chain coupled with synergies across all business units and countries allow us to fulfill the diverse requirements of the business we serve.

SourcingWe source ingredients for pharma and nutra industry from India as well as globally.

EggNovo

Generic name Product name Characteristics Applications

Calcium Carbonate Egg shell membrance calcium

Calcium Carbonate supplement Used in Bone health supplements

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Wacker Chemie AG, Germany


Coenzyme Q10 Cavamax W8 - CoQ10 complex

Highly bioavailable CoQ10, Enhancement in absorption of fat soluble nutrient

Cardiovascular health, anti-aging, energy supply

Curcumin Cavacurcumin: Cavamax W8 Curcumin

Highly bioavailable curcumin, easily dispersible in aqueous systems

Anticancer/antiinflammatory

Hydroxytyrosol HTEssence Tyrosinase inhibitor, vasoconstriction, melanocyte inhibition

Antioxidant for cardiovascular health/skin lightening

Cysteine L-Cysteine Synthesis is performed by metabolically optimized bacteria (Escherichia coli), breaks disulfide bridges in peptides and proteins

Radical scavenger, anti-aging

α-Cyclodextrin Cavamax W6 Food Soluble dietary fibre, lower glycemic index, fibre content min 98%, caloric value 2kcal/g

Weight management, energy metabolism, contributes balanced insulin flow, contols blood glucose

Horphag Research, Switzerland


French martime pine bark extract

Pycnogenol Activates the enzyme endothelial nitricoxide synthase (eNOS), present in endothelial cells, to more efficiently generate nitric oxide (NO) from the precursor amino acid L-arginine, Controls the levels of LDL and HDL, unique combination of procyanidins, bioflavonoids and phenolic acids

• Cardiovascular health – Improves endothelial function – Normalises high blood pressure• Diabetes• Joint health• Oral skin care/topical skin care• Sports nutrition• Erectile dysfunction

Centella Asiatica Centellicum Facilitates collagen remodulation Cardio vascular health

French oak extract Robuvit Increases ribosome generation and elevates protein synthesis activity, rejuvenates mitochondria for greater energy, metabolite urolithins increases muscle function

Chronic fatigue syndrome, liver function improver

Ashland Inc., USA


Fatty acid powder (Cetyl myristate) with maltodextrin

Celadrin VEGE Spray Dried esterified fatty acid powder using gum arabic and corn maltodextrin as carriers

Joint health nutrient

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NOF CORPORATION































Products



HTEssence

L-Cysteine

Cavamax W6 Food












EggNovo




Ashland Inc., USA


L-Arabinose & chromium

Prenulin Natural Glucose Support is a patent-pending ingredient

Helps to reduce the absorption of sugar

Ferronyl Iron Sprinkles

Ferronyl Iron Ready to use one time dosage in sachet form

Iron deficiency anaemia

Fermented vitamins and minerals

GPM (Glyco Protein Matrix) Nutrients

Glyco Protein Matrix (GPM) bound nutrients, processed by fermentation with yeast, bioavailable and effective form, improves absorption, easily digestible

Antioxidant, cardiovascular health, weight management, immune system regulator

Biotin 0.5% plus GPM

Boron 1% plus GPM

Calcium 5% plus GPM

Choline 25% plus GPM

Co enzyme q-10 plus GPM (8%)



Folic acid 1% plus GPM

Gtf chromium 0.2% plus GPM

Inositol 25% plus GPM

Iron 5% plus GPM

Magnesium 5% plus GPM

Manganese 5% plus GPM

Niacinamide 25% plus GPM

PABA 25% PLUS GPM

Pantothenic acid 25% plus GPM

Selenium 0.1% plus GPM

Selenium 0.2% plus GPM

Vanadium 0.1% plus GPM

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HTEssence

L-Cysteine

Cavamax W6 Food












EggNovo




Ashland Inc., USA


Fermented vitamins and minerals

Vanadium 0.2% plus GPM

Glyco Protein Matrix (GPM) bound nutrients, processed by fermentation with yeast, bioavailable and effective form, improves absorption, easily digestible

Antioxidant, cardiovascular health, weight management, immune system regulator

Vitamin b-1 25% plus GPM

Vitamin b-12 0.5% plus GPM



Zinc 5% plus GPM

Gtf chromium 0.2% plus GPM

Gehrlicher Herbal Extracts, Germany


Hintonia Hintonia Latiflora Extract

Components includes polyphenolic substances, essentially neoflavonoids. Liquid extracts (fluidum) from the bark of Hintonia latifiora

Improvement of glucose tolerance and management in Type 2 diabetes

Pfannenschmidt GmbH, Germany


Iron source Ferroplant Extract from curry leaves, Non-heme iron, contains Ferritin protein, resistant to proteolytic digestion

Highly bioavailable, rich dietary source of iron, increases the levels of hemoglobin

Soyabean Phytosterols

Avocadoflex Mixture of unsaponifiable fractionof Avocado and Soybean Phytosterols, Active constituents: Beta-Sitosterol, Campesterol, Stigmasterols

Cartilage protection in osteoarthritis

Morinaga, Japan


Bifidobacteria Probiotics Probiotic for general health Gut health

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HTEssence

L-Cysteine

Cavamax W6 Food












EggNovo




Benepure, China


Myo Inositol Inositol Womens health Menopause, PCOS

Citrus Aurantium Extract

Bitter Orange Extract Obesity Weight Management

Glac Biotech, Taiwan


ProNulife Gasprotech

Probiotics Probiotic for gastric support Gut health

ProNulife IntProtech Probiotics Probiotic for gut health and immunity Gut health

ProNulife NosRelieve Probiotics Probiotics for allergy and immune support

Gut health

ProNulifeFitStay Probiotics Probiotics for weight management Gut health

ProNulife VagProtech

Probiotics Probitics for vaginal health Gut health

ProNulife Ora Protech

Probiotics Probiotics for oral health Gut health

ProNulife BabyAllieve

Probiotics Probiotics for child health and immunity

Gut health

Post Biotic Powder Post Biotic Functional probiotics, byproducts of probiotic bacterial fermentation

Gut health, immunity, anti allergic, blood pressure, glucose, influenza, oral health, cancer, osteoporosis, blood lipid, atopic, dermatitis, liver health

Linnea, Switzerland


Bilberry Fruit Dry Extract

Bilberry Anti oxidant Eye health, Vasoprotection, antioxidant

Ginkgo Biloba Ginkgo Biloba Anti oxidant Brain Support,Cerebrovascular, Tinnitus

Red Clover Extract Red Clover Anti oxidant Anti ageing, menopausal symptoms

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HTEssence

L-Cysteine

Cavamax W6 Food












EggNovo




CEAMSA, Spain


Pectin Ceampectin ESS -4410 Extracted from citrus peel and standardized with dextrose, imparts excellent flavour release

Provides high gel strength and a long setting time in development of pectin gellies

Grace Davison Chemicals, USA


Silicon dioxide Syloid G 156 FP Large internal surface area, intra particle porosity with a medium pore volume. Particle size 4.6-5.8 µm, pore volume 1.2 ml/g

Exclusively as a glidant and anti-caking in solid oral dosage forms, highly adsorptive as carrier for liquids

Daicel Corporation, Japan


Co-processed excipient

Disperzista • Co-processed excipient: Lactose, cellulose, corn starch, pre-gelatinized starch• Low compression gives better hardness and disintegration • Disintegrates into a creamy consistency

• Co-processed excipient for ODT (direct compression) • Adds value in content uniformity• Filler for manufacturing dietary supplements

JMC Corporation, Korea


Sodium Saccharin Sodium Saccharin, 6% and 15% moisture

Use of high purity raw material OTSA (Ortho-Toluene sulfonamide) facilitates for efficient control on generation of impurities

Used as a sweetner in powder, granules, ODT and liquid orals of Nutraceutical formulations

Macco, Canada

Generic name Characteristics Applications

Organic mineral salts of calcium, potassium, ammonium, magnesium, sodium, zinc

Organic mineral salts Pharma, biopharma, infusion and dialysis solutions, chemical specialities

Glycerophosphates, glucoheptonates, lactates, gluconates, citrates, citric acid

Organic mineral salts Pharma and nutrition

We can source any product/s of your requirement, which may not be listed above

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NOF CORPORATION































Products



HTEssence

L-Cysteine

Cavamax W6 Food












EggNovo




Our core business

Disclaimer The information in this brochure is to our best knowledge true and accurate but, all instructions, recommendations or suggestions are made without guarantee. Since the conditions of use are beyond their control, DKSH disclaims any liability for loss or damage suffered for use of this data or suggestions. Furthermore, no liability is accepted if use of any product in accordance with this data or suggestions infringes any patent.

Fully compliant• Regulatory• Customs• FDA and audit complaint warehouses• Dedicated sample facility

Easy to work with• Market insights and intelligence• Warehousing/logistic support• Market development • Technical support/ troubleshooting• Sampling and regulatory documentation

Deliver value• High service level• Provide solution• Global company with local approach• Strong network and relationship in industry

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Proven operational efficiencyWe continuously improve the efficiency of our processes. The quality of our services is based on best practices and standards throughout our organization. An efficient

supply chain coupled with synergies across all business units and countries allow us to fulfill the diverse requirements of the business we serve.

SourcingWe source ingredients for pharma and nutra industry from across the world.

Your preferred partner for sourcing• Comprehensive global sourcing

network • Highly dedicated team of sourcing specialists


DKSH Group• Leading provider of Market Expansion Services• Total Sales CHF 11.3 billion (2018)• 33,000 employees in 35 markets and 825 business locations• More than 150 years in Asia

Business Unit Performance Materials• We source, develop, market and distribute a wide range of specialty chemicals and ingredients• Focus on industries and applications• Over 1,080 specialized staff in 31 markets• 29 innovation centers• 100 business locations

Business Lines• Pharmaceutical Industry• Food & Beverage Industry• Personal Care Industry• Specialty Chemicals Industry

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NOF CORPORATION































Products



HTEssence

L-Cysteine

Cavamax W6 Food












EggNovo




DKSH India Private LimitedFantree Building, Sarla Park, Andheri East, Mumbai 400059, IndiaPhone +91 22 6157 7000, Fax +91 22 2920 0210 www.dksh.in

Version: Nutraceuticals; April, 2019

AhmedabadPhone +91 79 6543 9950

DelhiPhone +91 11 2691 6320/21

KolkataPhone +91 33 4060 5527

MumbaiPhone +91 22 6157 7000

SecunderabadPhone +91 40 6649 1011

[email protected]

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NOF CORPORATION































Products



HTEssence

L-Cysteine

Cavamax W6 Food












EggNovo




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