11th Meeting Spanish Society for Developmental...

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11th Meeting Spanish Society for Developmental Biology GIRONA | 19-21 OCTOBER 2016

Transcript of 11th Meeting Spanish Society for Developmental...

Page 1: 11th Meeting Spanish Society for Developmental …sebd.es/wp-content/uploads/2016/12/AAFF_SEBD_PROGRAMA...12.00pm Isabel Fabregat, IDIBELL, Spain. TGF-beta: a targetable pathway in

11th Meeting Spanish Society for Developmental Biology

GIRONA | 19-21 OCTOBER 2016

Page 2: 11th Meeting Spanish Society for Developmental …sebd.es/wp-content/uploads/2016/12/AAFF_SEBD_PROGRAMA...12.00pm Isabel Fabregat, IDIBELL, Spain. TGF-beta: a targetable pathway in

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VENUEPalau de Congressos: Pg. de la Devesa, 35. 17001 Girona

All oral sessions will take place in Sala de Cambra.

Poster sessions, coffees, lunches and stands will be in the hall of Sala Cambra.

TECHNICAL SECRETARIAT TIMETABLEWednesday 19th October 2016: 9.30am – 8.30pm.

Thursday 20th October 2016: 8.30am – 8.00pm.

Friday 21st October 2016: 8.30am – 7.00pm.

CONGRESS LANGUAGEThe official language of the conference is English.

ORAL AND POSTER SESSIONSAuthors presenting an oral communication should be at the Sala de Cambra 30 minutes before their session starts to upload their presentation.

Authors presenting a poster should be in front of their poster during the poster session. Poster session I: even numbers | Poster session II: odd numbers

At the end of each session posters must be removed.

DINNERThe conference dinner will be on Friday 21st at Siloc Restaurant.Carretera dels Àngels Km 0.2. La Creueta. Girona | GPS 41.963935,2.845369

There will be a bus transfer from:Hotel Ultonia at 8.00pmHotel Double Tree Hilton 8.00pm

ASSISTANCE CERTIFICATESCertificates will be sent by email after the congress.

CONGRESS SECRETARIATTel. +34 933 196 [email protected]

General info

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Program

WEDNESDAY 19th October

9.30am–8.00pm Registration

Workshops

10.00am–1.00pm Genome editing: CRISPR and beyond Organizers: Lluís Montoliu and Joan Galceran

Single cell omics Organizers: Manuel Irimia and Ignacio Maeso

Cell dynamics and nanobiology Organizers: Maria Garcia-Parajo and Xavier Trepat

SEBD Meeting

3.45pm–4.00pm Welcome chair: ángela nieto

4.00pm–5.00pm The EMBO Keynote Lecture: Claude Desplan, New York University, US. Generation of neuronal diversity through temporal and spatial patterning chair: ángela nieto

5.00pm–7.00pm The Developmental Dynamics Opening Symposium Modelling cell behaviour and morphogenesis chair: miguel manzanares

5.00pm Michel Milinkovitch, Université de Genève, Switzerland. The EvoDevo & physics of skin appendage and skin colour patterning in vertebrates

5.30pm Roberto Mayor, University College London, UK. The molecular basis of gastrulation: a novel role of complement factors

6.00pm Richard Smith, MPI for Plant Breeding Research, Germany. Towards an integrated framework for computational MorphoDynamX

6.30pm Philipp Germann, Centre de Regulació Genòmica (CRG), Spain. Simulating large-scale epithelium-mesenchyme interactions

6.45pm Luís M. Escudero, Instituto Biomedicina de Sevilla, Spain. Fundamental physical cellular constraints drive self-organization of tissues

7.00pm–8.30pm Welcome Reception

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THURSDAY 20th October9.00am–11.00am Symposium: Evo-Devo and Genomics

chair: jordi garcía-fernández

9.00am Héctor Escrivà, Observatoire Océanologique de Banyuls, France. Amphioxus illuminates the origin of the vertebrates’ head

9.30am Benjamin Prud’homme, Institut de Biologie du Développement de Marseille, France. Evolution and development of wing pigmentation patterns in flies and beyond

10.00am Juan Pablo Couso, University of Sussex, UK. Small Open-Reading Frames include two molecular classes of metazoan protein-coding genes

10.30am Isabel Almudi, CABD, Spain. Understanding the origin of an evolutionary novelty: the male-specific turbanate eyes of the mayfly Cloeon dipterum

10.45am Cristian Cañestro, Universitat de Barcelona, Spain. Gene loss, pushing the limits of chordate Evo-Devo

11.00am–11.30am Coffee break

11.30am–1.00pm Symposium: Biological Oscillators chair: fernando casares

11.30am Paloma Mas, CRAG, Spain. Organ specificity at the core of the Arabidopsis circadian clock

12.00pm Jordi Garcia-Ojalvo, Universitat Pompeu Fabra, Spain. Metabolic oscillations in proliferating cellular populations

12.30pm Alexander Aulehla, EMBL, Germany. Oscillatory signaling dynamics controlling mouse embryo patterning

1.00pm–1.30pm Lunch box

1.30pm–3.00pm Poster Session I: even poster numbers

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3.00pm–4.30pm Postdoc Symposium: SEBD, SPBP and SEBC chair: pilar cubas

3.00pm Joaquín Letelier, Centro Andaluz de Biología del Desarrollo, Spain. The emergence of the rac3b/rfng/sgca synexpression group in the Osta-riophysi superorder refined the mechanisms responsible for rhombomere segregation during hindbrain development

3.15pm Miguel Moreno, Center for Plant Biotechnology and Genomics, Uni-versidad Politécnica de Madrid, Spain. Positioning new root organs through oscillating gene expression: new fac-tors integrate auxin hormone signaling and specification of cell identity

3.30pm Miguel Murillo, The Crick Institute / Institute of Cancer Research, UK. Disruption of the interaction of RAS with PI 3-kinase induces regression of EGFR-driven lung cancer

3.45pm Paulo Navarro-Costa, Instituto Gulbenkian de Ciência, Portugal. Early programming of the oocyte epigenome temporally controls late pro-phase I transcription and chromatin remodeling

4.00pm Óscar Ocaña, Instituto de Neurociencias de Alicante, Spain. A left-right differential cell migration drives heart bending in vertebrates.

4.15pm Ligia Tavares, I3S/IBMC, Portugal. Drosophila PS2 and PS3 integrins play distinct roles in retinal photorecep-tors-glia interactions

4.30pm–5.00pm Coffee break

5.00pm–6.00pm The ISDB-MOD Keynote Lecture: Magdalena Götz, Munich Center for Neurosciences, Germany. Mechanisms of neurogenesis and repair chair: víctor borrell

6.30pm–7.30pm SEBD general assembly at Sala Cambra SPBD general assembly at Sala Premsa

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FRIDAY 21th October9.00am–11.00am Symposium: Cell Biology

chair: marian ros

9.00am Fernando Martín-Belmonte, Centro de Biología Molecular, Spain. Signaling pathways in epithelial morphogenesis and patterning in tubular organs

9.30am Helder Maiato, Instituto de Biologia Molecular e Celular, Portugal. Cracking the mitotic code

10.00am Rosa Ríos, CABIMER, Spain. Microtubule assembly in centrosome-less mammalian cells

10.30am Sofia Araujo, IBMB-CSIC, Spain. Centrosome amplification increases single-cell branching in post-mitotic cells

10.45am Sol Sotillos, CABD, Spain. A novel function of aPKC controlling apical cell trafficking

11.00am–11.30am Coffee break

11.30am–1.00pm Symposium: Signalling in Development and Disease chair: paola bovolenta

11.30am Isabel Guerrero, Centro de Biología Molecular, Spain. Cellular synapses for Hedgehog signaling

12.00pm Isabel Fabregat, IDIBELL, Spain. TGF-beta: a targetable pathway in liver diseases?

12.30am Marco Milán, IRB, Spain. JAK/STAT controls organ size and fate specification by regulating morphogen production and signalling

12.45am Pablo Menéndez, Josep Carreras Leukaemia Research Institute, Spain. Proinflammatory signaling is dispensable for in vitro human hematopoietic specification from hPSCs

1.00pm–1.30pm Lunch box

1.30pm–3.00pm Poster Session II: odd poster numbers

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3.00pm–5.00pm Symposium: Neural Development chair: berta alsina

3.00pm Domingos Henrique, Instituto de Medicina Molecular, Portugal. The Notch ligands Dll1 and Dll4 have non-redundant functions in the developing mouse neural retina

3.30pm Nuria Flames, Instituto de Biomedicina de Valencia, Spain. Deep homology of the serotonergic transcriptional code in nematodes and mammals

4.00pm Víctor Borrell, Instituto de Neurociencias, Spain. Genetic control of cerebral cortex expansion

4.30pm Francisca Vasconcelos, Instituto Gulbenkian Ciencia, Portugal. MyT1 counteracts the neural progenitor program to promote vertebrate neurogenesis

4.45pm Marta Nieto, CNB-CSIC, Madrid. Cux1 enables inter-hemispheric connections of layer II-III neurons by regulating Kv1-dependent firing

5.00pm–5.30pm Coffee break

5.30m–6.30pm Keynote Lecture: Rainer Friedrich, FMI, Switzerland. Deconstruction and reconstruction of olfactory neuronal circuits in zebrafish chair: berta alsina

6.30pm Concluding remarks and farewell chair: berta alsina and ángela nieto

8.30pm Conference Dinner

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Poster list

THURSDAY 20 | poster session i: even poster numbers

FRIDAY 21ST | poster session ii: odd poster numbers

MODELLING CELL BEHAVIOUR AND MORPHOGENESIS1 Cytoskeletal rearrangements driven by a Notch-BMP2 signalling cascade

underlie the emergence of the proepicardium in the zebrafish

Andrés-Delgado Laura, Bazaga David, Peralta Marina, Münch Juliane, Galardi-Castilla Maria, Vermot Julien, de la Pompa Jose Luis, Mercader Nadia

3 Genetic control of cell geometry in epithelia: the morphogenesis of the verte-brate optic cup as experimental paradigm

Buono Lorena, Naranjo Silvia, Moreno -Mármol Tania, Bovolenta Paola, Martinez- Morales Juan Ramon

4 Live analysis of MYC-regulated spontaneous cell competition in mouse ESCs

Díaz-Díaz Covadonga, Fernández-de-Manuel Laura, JIménez-Carretero Daniel, Montoya María, Torres Miguel

5 A mathematical model of tissue growth based on progenitor-to-differentiated state transition

Sánchez-Aragón Máximo, Ramaekers Arianne, Almudi Isabel, Martín-Blanco Carlos, Hassan Bassem, Casares Fernando

6 Does tension keep you in shape? Relevance of Drosophila melanogaster peripodial epithelium on final organ size

Villa-Fombuena Gema, Gómez-Gálvez Pedro, Escudero Luis M., Casares Fernando

7 Regulation of expression and functions of Hox complex by Meis transcription factors

Lopez-Delgado Alejandra Cristina, Cadenas-Rodriguez Vanessa C., Torres Miguel

8 Neurovascular interaction in the vertebrate inner ear and brain

Taberner Laura, Alsina Berta

9 Mutations of genes involved in the early-eye morphogenesis in zebrafish

Undurraga Cristian, Letelier Joaquin, Vazquez-Marin Javier, Martinez-Morales Juan

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10 Analysis of YAP/TAZ-dependent transcriptional response during epithelial morphogenesis in teleost embryos

Vázquez-Marín Javier, Gutiérrez-Triana José Arturo, Letelier Joaquín, Buono Lorena, Miesfeld Joel B., Link Brian A., Mateo Juan L., Wittbrodt Joachim, Martínez-Morales Juan Ramón

11 HoxD13 and its targets and the evolution of vertebrate limbs

Castro João, Beviano Vanessa, Paço Ana, Freitas Renata

12 Unraveling RPE morphogenesis and its influence in optic cup folding

Moreno-Mármol Tania, Salgüero Sergio, Cavodeassi Florencia, Bovolenta Paola

13 Molecular and cellular mechanisms controlling cell rearrangement during development

Molina Gil Sara, Espinisa Vázquez José, Castelli-Gair Hombría James

14 Cell number and body size regulation

Saló Emili, de Sousa Nidia, Pascual-Carreras Eudald, Adell Teresa

15 Tracing the fate of yolk sac hemangioblasts in the chick embryo

Tavares Ana Teresa, Martins Gabriel G., Jacinto Antonio

16 STAGER, staging tool for the analysis of expression results

Magno Ramiro, Andrade Raquel, Marée Athanasius, Palmeirim Isabel

17 Sculpting cavities: the relevance of Lumen Initiation Foci (LIF) for lumen shape

Hoijman Esteban, Alsina Berta

18 Development of a new micropattern-based platform to study the role of cell adhesion in tubulogenesis

Bosch Minerva, Rodríguez Fraticelli Alejo, Delgado Barea María, Hachimi Mariam, Martín Belmonte Fernando

EVO-DEVO AND GENOMICS19 Two recently evolved isoforms of the BRANCHED1a gene fine-tune the develo-

pment of aerial and subterranean architecture in Solanum tuberosum

Nicolas Michael, Rodríguez-Buey María Luisa, Franco-Zorrilla José Manuel, Cubas Pilar

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20 miR-15/16 family, a regulatory node for cell plasticity in search for a revised nomenclature

Arcas Aida, Rago Luciano, Nieto Ángela M.

21 Regulation of early mammalian embryo development through alternative splicing

Pernaute Barbara, Wyatt Chris D R, Irimia Manuel

22 Characterization of potential sources of extrinsic influences on cortical proge-nitors in gyrencephalic brains

de Juan Romero Camino, Reillo Isabel, Cárdenas Adrián, Clascá Franscisco, Borrell Víctor

23 Oct4 is a key regulator of vertebrate trunk length diversity

Aires Rita, D. Jurberg Arnon, Leal Franscisca, Nóvoa Ana, J. Cohn Martin, Mallo Moisés

24 Attenuation of Robo signaling promotes cerebral cortex expansion in evolution

Cárdenas Adrián, De Juan Romero Camino, Picó Esther, Navarro Maria del Carmen, Villalba Ana, Tzika Athanasia, Tessier-Lavigne Marc, Milinkowitch Michel, Martínez Luis Miguel, Borrell Victor

25 A comprehensive pipeline for identifiying lincRNAs on the basal-branching chordate amphioxus

Herrera Carlos, Albuixech-Crespo Beatriz, Burguera Demian, Irimia Manuel, Garcia- Fernandez Jordi

26 Evolution of developmental gene complexes in Drosophila: What can we learn?

Negre Bàrbara, Muyas Francesc, Guillén Yolanda, Ruiz Alfredo

27 Origins and regulation of an eutherian novelty: the BGW cluster

Navas Enrique, Burguera Demian, Vicente Cristina, Ferran Jose Luis, d’Aniello Salvatore, Puelles Luis, Irimia Manuel, Carvajal Jaime, Garcia-Fernàndez Jordi

28 3D chromatin organisation and enhancer-promoter specificity

Vicente-García Cristina, López-Mayorga Macarena, Irastorza Ibai, Tena Juan, Devos Damien, Gómez-Skarmeta Jose Luis, Carvajal Jaime

29 The evolution of Xenacoelmorph nervous systems (a case of evolutionary centralization)

Gavilán Brenda, Perea-Atienza Elena, Martínez Pedro

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30 Deconstructing the genetic toolkit for heart development in a chordate

Ferrández-Roldán Alfonso, Plana-Carmona Marcos, Almazán-Almazán Alba, Moncusí Anna, Bujosa Paula, Diaz-Gracia Miriam, Martí-Solans Josep, Davidson Brad, Albalat Ricard, Cañestro Cristian

31 Muscle development and tail elongation in Oikopleura dioica, a chordate evolutionary knockout for retinoic acid signaling

Almazán-Almazán Alba, Plana-Carmona Marcos, Moncusí Anna, Ferrández-Roldán Alfonso, Diaz-Gracia Miriam, Martí-Solans Josep, Cañestro Cristian, Albalat Ricard

CELL BIOLOGY32 Identification of pathogenic bacteria in pepper seedlings

González García Juvencio, Sáenz Hidalgo Hila Karina, Ávila Quezada Graciela Dolores, Guerrero Morales Sergio

33 Influence of Notch on the development and fate of the hemogenic endothelium using mouse genetic mosaics

Laruy Briane, Benedito Rui

34 Integrins positively regulate cell survival in the wing imaginal disc in Drosophila melanogaster

Valencia Expósito Andrea, Gómez Lamarca María Jesús, J. Widmann Thomas, Martín Bermudo María Dolores

35 Role of integrins in epithelial architecture in Drosophila ovary

Santa-Cruz Mateos Carmen, Grosheva Inna, Palacios Isabel, González Reyes Acaimo, Martín Bermudo Maria Dolores

36 Coelomic epithelium-derived cells migrate into the developing pancreas and contribute to the stellate cell population in mice

Cañete Ana, Ariza Laura, Muñoz-Chápuli Ramón, Carmona Rita

37 Expression of the Wilms tumor suppressor gene (Wt1) in a subpopulation of embryonic cardiomyocytes is required for cardiac development

Carmona Rita, Cañete Ana, Ariza Laura, Torrado Mario, Mikhailov Alexander, Muñoz- Chápuli Ramón

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38 Overexpression of Hif2a in mouse hepatic stellate cells induces liver fibrosis

Villamayor Coronado Laura, Rojas Anabel

39 The role of SNBPs in the differential susceptibility to genotoxic damage within the sperm nucleus

González-Rojo Silvia, Fernández-Díez Cristina, Lombó Marta, Herráez M. Paz

40 Scratch factors in the neural stem cell niche

González-Iglesias Ainara, Domingo-Muelas Ana, Fariñas Isabel, Nieto M. Ángela

41 WIP (WASP Interacting Protein) drives tumor progression through YAP/TAZ- dependent autonomous cell growth

Gargini Ricardo, Escoll Maribel, Garcia Esther, Garcia-Escudero Ramon, Wandosell Francisco, Anton Ines M

42 Optimization of adoptive cell transfer therapy through the combination of magnetic targeting and p85 down-regulation

Sanz-Ortega Laura, Rojas José M., Barber Domingo F.

43 SCOX partial loss of function causes mitochondrial disruption and skeletal muscle wasting in drosophila melanogaster

Laine Sara, Becedas José María, Serna Roberto, Tornero Alba Rocío, Rodriguez Sonia, Martí Yolanda, Garesse Rafael, Cervera Margarita, Arredondo Juan José

44 Autophagy and cathepsins are activated with programmed cell death in stress-induced microspore embryogenesis and pollen development

Solís María-Teresa, Bárány Ivett, Berenguer Eduardo, Santamaría Estrella, Crespo José-Luis, Díaz Isabel, Risueño María-Carmen, Testillano Pilar S.

45 Sea urchin sperm express cannabinoid receptors in mitochondrial region and flagellum

Francou Manuela, de Juan Alba, Girela José Luis, Ten Jorge, Bernabeu Rafael, De Juan Joaquín

46 Functional requirements of Cubilin orthologues in Drosophila nephrocytes

Atienza Alexandra, Ruiz Mar

47 Silencing caveolin-1 or clathrin inhibits TGF-ß-induced anti-apoptotic signals in liver cells

Caballero-Díaz Daniel, Moreno-Càceres Joaquim, Nwosu Zeribe, Meyer Christoph, Dooley Steven, Egea Gustavo, Fabregat Isabel

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48 Modeling coenzyme Q10 deficiency-associated phenotype using patient-specific IPS cells

Romero-Moya Damià, Santos-Ocaña Carlos, Castaño Julio, Garrabou Gloria, Artuch Rafael, Muñoz-Canoves Pura, Navas Placido, Menéndez Pablo

49 In microspore reprogramming to embryogenesis auxin biosynthesis and transport are induced while they decrease during gametophytic development

Risueño María Carmen, Rodríguez-Sanz Héctor, Pérez-Pérez Yolanda, Solís María- Teresa, López María-Fernanda, Gómez-Cadenas Aurelio, Testillano Pilar S.

50 TGF-ß-induced partial EMT offers to hepatocellular carcinoma the highest advantage for a migratory stemness phenotype

Malfettone A. , Soukupova J. , Fernando J. , Koudelkova P. , Bertran E. , Fabra À., Grubinger M. , Mikulits W., Giannelli G., Fabregat I.

51 Melatonin effects on glucose metabolism of cancer cells

Sanchez-Sanchez Ana Mª, Puente-Moncada Noelia, Antolin Isaac, Rodriguez Carmen, Martin Vanesa

52 BMP9: A novel regulator of oval cell function during chronic liver injury. Crosstalk with the HGF/c-Met pathway

Addante Annalisa, García-Álvaro María, Roncero César, Fernández Margarita, Almalé Laura, Lazcanoiturburu Nerea, Sanz Julian, Saperas Patricia, Fabregat Isabel, ten Dijke Peter, Herrera Blanca, Sánchez Aránzazu

53 Potentiation by melatonin of gemcitabine effect on mutant FLT3-ITD acute myeloid leukemia cells

Puente-Moncada Noelia, Sánchez-Sánchez Ana Mª, Antolín Isaac, Rodríguez Carmen, Martín Vanesa

54 Identification of conserved MEL-28/ELYS domains with essential roles in nuclear assembly and chromosome segregation

Gomez-Saldivar Georgina, Fernandez Anita G., Ritler Dominic, Hirano Yasuhiro, Lai Allison, Mauro Michael, Ayuso Cristina, Haraguchi Tokuko, Hiraoka Yasushi, Piano Fabio, Meister Peter, Askjaer Peter

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SIGNALLING IN DEVELOPMENT 55 A connection between male abdominal segment elimination and the genitalia

rotation

Prieto Nuria, Olivera Inés, Sánchez-Herrero Ernesto

56 Smed-egfr-1 controls gut progenitor differentiation during planarian regeneration and homeostasis

Barberán Sara, Cebrià Francesc

57 Meis function in limb antero-posterior patterning

Delgado Irene, Torres Miguel

58 Tbx5 genes in early zebrafish development

Pi-Roig Aina, Minguillón Carolina, Garcia-Fernàndez Jordi

59 Canoe loss synergistically interacts with scribble mutants to promote tumor growth via ras activation

Rives-Quinto Noemí, Carmena Ana

60 Epigenotoxic effects of bisphenol A impair heart development

Lombó Alonso Marta, Fernández Díez Cristina, Gonzalez Rojo Silvia, Herráez Ortega Paz

61 Uncovering novel therapeutic targets for p63-related hereditary malformations

Santos Pereira José María, Tena Juan J.

62 Patterning-Hox interaction during organogenesis: regulation of the Drosophila Six3 gene Optix during wing and haltere development

Al Khatib Amer, Casares Fernando

63 Dechipering the regulatory transcriptional network controling Drosophila wing disc regeneration

Vizcaya Elena, Klein Cecilia, Serras Florenci, Guigó Roderic, Corominas Montserrat

64 Segment identity changes during imaginal disc regeneration

Juárez Uribe RA, Herrera SC, Morata G, Sánchez-Herrero E.

65 Translating a static signaling source into a dynamic patterning process: the role of Hh signaling in the differentiation of Drosophila ocellus

García Morales Diana, Gómez Míguez David, Casares Fernando

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66 Mosaic levels of Notch activity are necessary for regulated endothelial cell proliferation during vascular development

Pontes-Quero Samuel, Hermoso Ana, Merino Javier, Heredia Luis, Benedito Rui

67 Live analysis of Drosophila female germline stem cells reveals a role for ECM-regulator Timp in stem cell division

Lobo Pecellín María, González Reyes Acaimo

68 miR-106 regulates muscle repair through control of muscle stem cell fate

Hernández-Torres Francisco, Vallejo Daniel, Rodríguez-Outeiriño Lara, Franco Diego, Aránega Amelia

69 Tolerance to defective zygotic repair of paternal DNA damage in external fertilizers

Fernández Díez Cristina, González Rojo Silvia, Lombó Alonso Marta, Herráez Ortega M. Paz

70 High-throughput analysis of proximo-distal transcriptional profiles in limb development

Fernández-Guerrero Marc, Pérez-Gómez Rocío, Darbellay Fabrice, Delisle Lucille, Duboule Denis, Ros Marian

71 Analysis of the mechanism underlying the function of Sp6 and Sp8 in the limb ectoderm

Pérez-Gómez Rocío, Fernández-Guerrero Marc, Zunzunegui Sandra, López-Giménez Juan F., Ros Marian

72 Understanding Cdon-Hh interaction in zebrafish eye formation

Gallardo Viviana, Letelier Joaquin, Sandonis Africa, Cardozo Marcos, Martinez-Morales Juan Ramon, Bovolenta Paola

73 Breaking the Atoh1 autoregulatory loop in neurosensory precursors: the repression of Atoh1 by Neurog1 during inner ear development

Galvez García Héctor, Tena Juan J., Giraldez Orgaz Fernando, Abello Gina

74 The Intermediate Mesoderm, a new player in the establishment of organ laterality?

Silva Dalila, Fernandes Sara F., Saúde Leonor

75 Retinoic acid regulates chamber specification through miR-133 during early heart looping formation

Garcia-Martinez Virginio, Franco Diego, Garcia-Lopez Virginio, Aranega Amelia, Lopez-Sanchez Carmen

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76 Role of miR-130 in Bmp2 pathway signalling during cardiac atrial differentiation

Lopez-Sanchez Carmen, Franco Diego, Garcia-Lopez Virginio, Aranega Amelia, Garcia-Martinez Virginio

77 Alternative splicing control over naïve and primed pluripotency throughout mammalian embryo development

Rodríguez-Vaello Victoria, Pernaute Bárbara, Irimia Manuel

78 Elucidating novel functions for the EGF receptor pathway during liver regene-ration and hepatocarcinogesis

López-Luque Judit, Caballero-Díaz Daniel, Martinez-Palacián Adoración, Roncero César, Crosas-Molist Eva, Bertran Esther, Serrano Teresa, Segovia Jose-Carlos, Fernández Margarita, Ramos Emilio, Sánchez Aránzazu, Fabregat Isabel

79 Hippo signaling controls cell death, cell cycle and differentiation in planarians

de Sousa Nidia, Cardona Heura, Saló Emili and Adell Teresa

80 WNT5-ROR and Slit-ROBOc signals generate a mutually dependent system to position the cns along the medio-lateral axis in planarians

Almuedo-Castillo Maria, Rojo-Laguna Jose-Ignacio, Sekaran Thileepan, Bartscherer Kerstin, Adell Teresa

81 Molecular mechanisms involved in naso-temporal patterning of the retina in zebrafish

Hernández Bejarano María, Cavodeassi Madarro Florencia, Bovolenta Nicolao Paola

82 RUNX1c regulates hematopoietic differentiation of human embryonic stem cells through activation of pro-inflammatory signaling

Navarro-Montero Oscar, Ayllon Veronica, Elefanty Andrew, Menendez Pablo, Real Pedro J.

83 ROS-induced signaling is required for Drosophila imaginal disc regeneration

Santa Bárbara Ruiz Paula, Serras Florenci, Corominas Montserrat

84 Functional relationship between Snail1 and Prrx1 EMT transcription factors in embryonic development

García-Asencio Francisco, Ocaña Oscar H., Nieto M. Angela

85 Regenerative response of different territories of the Drosophila wing imaginal disc

Martín Raquel, Morata Ginés

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86 Diversity of fate outcomes in cell pairs under lateral inhibition

Martinez Corral Rosa, Guisoni Nara, Garcia Ojalvo Jordi, de Navascués Joaquín

NEURAL DEVELOPMENT87 Deciphering the molecular function of the novel nuclear protein Trnp1 in brain

development

Esgleas Miriam, Forné Ignasi, Niessing Dierk, Imhof Axel, Götz Magdalena

88 Dissecting the role of Yap/Taz-TEAD activity in a pool of hindbrain progenitors

Voltes Adria, Fernandez Covadonga, Calzolari Simone, Terriente Javier, Pujades Cristina

89 Role of cell dynamics in neuronal specification of the zebrafish inner ear

Hoijman Esteban, Fargas Laura, Alsina Berta

90 The role of the acetyltransferase CBP in neural development

Gonzalez-Martinez Rocío, del Blanco Beatriz, Herrera Eloísa, Barco Angel

91 The ciliary margin zone of the mammalian retina generates retinal ganglion cells

Murcia-Belmonte Veronica, Marcucci Florencia, Coca Yaiza, Ferrero-Galve Susana, Kuwa-jima Takaaki, Wang Qing, Khalid Sania, Ross M Elizabeth, Mason Carol, Herrera Eloisa

92 The role of the synaptic protein Sv2b in embryonic development of the cerebral cortex

Villalba Requena Ana

93 Looking for mechanisms to increase the neural potential of neuro-mesodermal progenitors

de Lemos Luisa, Aires Rita, Póvoa Ana, Mallo Moises

94 Molecular mechanisms regulating wiring specificity

Fernández Pineda Alejandra, Morey Marta

95 The role of glial ionic homeostasis in glia-neuron communication

Zhu Qi, Plazaola Haritz, Gaitán-Peñas Héctor, Estévez Raúl, Morey Marta

96 Role of non-canonical Wnt pathway during cellular organization and diferentia-tion in spinal neural plate development

Lopez-Escobar B., Caro-Vega J.M., Vijayraghavan D., Plageman T.F., Sanchez-Alcazar J.A., Davidson L.A., Ybot-González P.

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97 Neuroblastoma cancer stem cells modulation by Nxph1/alpha-Nrxn system

Fanlo Lucia, Le Dréau Gwenvael, Gomez-Gomez Soledad, Lavarino Cinzia, Martí Elisa

98 Developmental mechanisms underlying chick secondary neurulation

González-Gobartt Elena, Marti Elisa

99 A mouse model of DYRK1A-related intellectual disability syndrome shows altered gliogenesis and defects in myelination

Pijuan Isabel, Balducci Elisa, Fernández Eduardo, Arbonés Mariona, Barallobre Maria José

100 Trisomy of the down syndrome DYRK1a gene favors apical versus basal neuro-genesis reducing the ratio of parvalbumin/somatostatin cortical interneurons

Najas Sonia, Arranz Juan, Pijuan Isabel, Barallobre Maria Jose, Arbones Mariona

101 ZEB1 promotes transcription of invasiveness genes in glioblastoma multiform cancer stem cells via a novel LEF1/TCF dependent mechanism

Rosmaninho Pedro, Mükusch Sunanne, Teixeira Vera, Raposo Alexandre, Momma Stefan, Castro Diogo

102 Study of the role of Ebf-1 in medium spiny neurons specification and maturation

Guardia Pena Ines, Martín Ibáñez Raquel, Canals Coll Josep M.

103 FLRT adhesion molecules regulate cerebral cortex folding by controlling neuron migration

del Toro Daniel, Ruff Tobias, Cederfjäll Erik, Villalba Ana, Seyit-Bremer Gönül, Borrell Víctor, Klein Ruediger

104 Generation of Vsx1/Vsx2 transcription factor double mutant in zebrafish using Crispr/cas9 system

González Díaz Sergio, Letelier Joaquín, Martínez Morales Juan Ramón

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