10 mV 100 ms 5 s 10 mV 5 s Transient current injection to the cell can toggle its state.
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Transcript of 10 mV 100 ms 5 s 10 mV 5 s Transient current injection to the cell can toggle its state.
Involvement of AMPA receptors in LTD induction.
Pairing PF-mediated EPSPs with depolarization of PCs
Pairing quisqualate application with depolarization of cultured PCs
Involvement of mGluR1 and PKC in LTD induction.
In the presence of antibodies inactivating mGluR1
control
The same in knockout mice lacking functional mGluR1
BAPTA
PKC (19¯36)
PKC(glu27) (19¯36)
Control
Expression of PKC in L7-PKC mice
Glutamate+Depolarization
LTD in L7-PKC mice
VOR gain change in L7-PKC mice
Involvement of PKC activation in LTD induction .
BAPTA
PKC (19¯36)
PKC(glu27) (19¯36)Control
NOS inhibitor L-NMMA
Control