10 15a 4 Atlas Neuroanatomy

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1 ATLAS NEUROANATOMY Somatosensory System Dorsal Column-Medial Lemniscal System Spinal Cord Forebrain Brainstem Dr. Donald Wong Anterolateral System Trigeminal System

Transcript of 10 15a 4 Atlas Neuroanatomy

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ATLAS NEUROANATOMYSomatosensory System

•Dorsal Column-Medial Lemniscal System

Spinal Cord

Forebrain

Brainstem

Dr. Donald Wong

•Anterolateral System

•Trigeminal System

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Dorsal Column-Medial Lemniscal System

Haines Atlas (7th) 8-4

•Discriminative (fine) Touch

•Position sense

•Vibratory sense

•2-point discrim.

•Stereognosis

Midbrain

Pons

Medulla

SpC

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Haines Atlas (7th) 6-1

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??? DC-ML

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Haines Atlas (7th) 6-1

Dorsal Column: fasciculus gracilis

Sacral level DC-ML

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5Haines Atlas (7th) 6-3

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DC-ML

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?

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6Haines Atlas (7th) 6-3

Fasc. gracilis

Fasc. cuneatus

T4 level

T6 and above

Dorsal Columns

Dorsal root (medial): large dia.

DC-ML

uT

L

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Haines Atlas (7th) 6-5

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DC-ML

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Haines Atlas (7th) 6-5

C1 level

FG

FC

FG

FC

CST fibers decussating

DC-ML

Post. Intermediate sulcus

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9Haines Atlas (7th) 6-8

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DC-ML

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10Haines Atlas (7th) 6-8

Pyramidal decussation

DC-ML

Caudal Medulla: DCN / x- Pyr

GrNu

CuNu

CuFs

GrFs

DCN

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Haines Atlas (7th) 6-9

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DC-ML

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Haines Atlas (7th) 6-9

Caudal/Mid Medulla: DCN

G. N. & fasc.

C.N.

C.N.

Medial lemniscus

DC-ML

Internal arcuate fibers

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13Haines Atlas (7th) 6-11

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DC-ML

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14Haines Atlas (7th) 6-11

MLF

TST

ML

Rostral Medulla: XII n. nucleus/ Inf. Olive

arm

leg

ML somatotopy: “Man standing on top of pyramid”

XIIXII

DC-ML

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15Haines Atlas (7th) 6-17

Lower pons: level of facial colliculus, VII n./nucleus

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DC-ML

**

*

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16Haines Atlas (7th) 6-17

Lower pons: level of facial colliculus, VII n./nucleus

arm

leg

DC-ML

**

*

Tegmentum

Base

MCP

ML

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Haines Atlas (7th) 6-20

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DC-ML

*

*

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Haines Atlas (7th) 6-20

Rostral pons/Caudal midbrain: level of V n./ IV n. exits

V nerve

IV nerve

ML

arm

leg

DC-ML

*

*

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Haines Atlas (7th) 6-22

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DC-ML

* *

*

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Haines Atlas (7th) 6-22

Caudal midbrain: Level of Inf. Colliculus

Rostral pons

ML

arm

leg X SCP

DC-ML

* *

*

Crus Cerebri

Crus Cerebri

Pons

Midbrain

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21Haines Atlas (7th) 6-25

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???

DC-ML

*

*

*

*

*

*

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22Haines Atlas (7th) 6-25

ML

Rostral midbrain: III-n. nucleus, SC, R.N.

DC-ML

*

*

*

*

*

*

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Haines Atlas (7th) 6-26

MLarm

leg

Midbrain/diencephalic junction: level of pretectal area/PC

DC-ML

* *PC

*

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Haines Atlas (7th) 6-30 Thal

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DC-ML

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Haines Atlas (7th) 6-30 Thal

III

Ant.

Post.

Pulvinar

CMVPL

VPMIntCap-post

Pineal

Forebrain (oblique axial): VP/ Pulvinar, CM, Pineal

SS Rad.

DC-ML

MD

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26Haines Atlas (7th) 6-33

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Oblique coronal

DC-ML

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27Haines Atlas (7th) 6-33

Int. Caps.: posterior limb

Oblique coronal

DC-ML

Somatosensory radiations

Level of Ant Thalamic Nucleus & SubThalamus

SubThal

Subst Nigra

Subst Nigra

Ant Ant

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Dorsal Column-Medial Lemniscal System

ArmLeg

Somatotopic representation in SI

•Leg - medial (ACA)

•Arm- lateral (MCA)

Haines Atlas (7th) 8-4

•Accurate stimulus localization possible if projs. mapped somatotopically (homunculus) in cerebral cortex

Int. Caps.

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Anterolateral System

ALS

•Pain/Temperature

•Light (crude) touch

•ALS pathways: Spinothalamic, Spinoreticular, Spino-tectal (mesencephalic)

•At least 20 neurons

•Lower brainstem: ALS

•Upper midbrain: mainly Spinothalamic Tract (spinal lemniscus)

Haines Atlas (7th) 8-6

Spinal lemniscus

ALS

ALS

VPL

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Large-dia. myelinated fibers: medial entry

Dorsolateral tract of

Lissauer

Haines Atlas (7th) 6-2

P/T fibers: lateral entry

Substantia galatinosa: lamina II

ALS: tract fibers- arise from superficial & deep DH layers

ALS: Spinothalamic, Spinoreticular, Spinotectal

ALS

AWC

Lumbosacral Enlargement (L4)

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31Haines Atlas (7th) 6-4

arm

leg

C7: Cervical enlargement

ALS

ALSALS

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Haines Atlas (7th) 6-9

Caudal/mid Medulla: DCN

G. N. & fasc.

C.N.

C.N.

Medial lemniscus

ALS

ALS

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Haines Atlas (7th) 6-12

ALS

Rostral Medulla

Cochlear nucleus

ALS

*

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34Haines Atlas (7th) 6-17

Lower pons: level of facial colliculus, VII n./nucleus

ML

ALS

VII (motor) nucleus

ALS

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Haines Atlas (7th) 6-19

ML

ALS

Midpons: V nerve entry (chief sensory/motor V)

ALS

S M

V nerve

Base

Tegmentum

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Haines Atlas (7th) 6-23

ML

ALS: spinal lemniscus

ALS

Lower midbrain: Trochlear (4th) nucleus/ x- SCP

4th 4th

x- SCPSubs. Nigra

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37Haines Atlas (7th) 6-25

ML

Rostral midbrain: III-n. nucleus, SC, R.N.

spinal lemniscus

ALS

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Haines Atlas (7th) 6-30

III

Ant.

Post.

pulvinar

CMVPL

VPMIntCap-post

Pineal

Forebrain (oblique axial): VP/ Pulvinar, CM, Pineal

& Subthalamus

ALS

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39Haines Atlas (7th) 6-31

MDLat.

Int. Caps.: posterior limb

ALS

Somatosensory radiations

LD

Forebrain coronal thru LD/ Subthalamus

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Anterolateral System

Somatotopic representation in SI

•Leg- medial

•Arm- lateral

Arm Leg

ALSHaines Atlas (7th) 8-6

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VTTT

Trigeminal System

3 brainstem sensory nuclei:

•Chief sensory

•Spinal trigeminal nucleus

•Mesencephalic nucleus V

•Fine touch, vibration

•Pain/temp. (V, VII, IX, X)

•Proprioceptive

•VTTT: x trig. pathway•ALL P/T AND

•DTTT: un-x trig. Pathway •Fine touch only

DTTT

TrigHaines Atlas (7th) 8-9

•Midpons- V-nerve entry

•Midpons thru medulla

•MOST fine touch, vibration

VII

IX

X

V

•Starts above midpons

•Fully formed in midbrain

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Haines Atlas (7th) 6-8

Spinal Trig. Nucleus/tract of V

Pyramidal decussation

Trig

Caudal Medulla: DCN/pyramidal decus.

DCN DCN

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Haines Atlas (7th) 6-11

MLF

TST

ML

Rostral Medulla: XII n. nucleus/ Inf. Olive

XIIXII

Sp Trg Tr & Nu V

Sp Trg Nu & Tr V

VTTTVTTT is lateral to Medial Lemniscus in medulla (no DTTT)

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44Haines Atlas (7th) 6-16

Lower pons: facial colliculus

Spinal Trig. Nucleus/tract of V-

lateral to VII n.

Trig

* *

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45Haines Atlas (7th) 6-19

S M

Chief sensory V

Mesencephalic V

Trig

VTTT

VTTT dorsal to ML

No DTTT

ML

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DTTT

VTTT

Haines Atlas (7th) 6-20

Rostral pons/Caudal midbrain: level of V n./ IV n. exits

V nerve

IV nerve

ML

Trig

ALS

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Haines Atlas (7th) 6-22

Caudal midbrain: Level of Inf. Colliculus

Rostral pons

ML

X SCP

VTTT

DTTT

Spinothalamic Tract

Trig

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Haines Atlas (7th) 6-26

MLSpinothalamic

tract

DTTT

VTTT

Trig

ML

Midbrain/diencephalic junction: level of pretectal area/PC/pineal

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Haines Atlas (7th) 6-30

III

Ant.

Post.

pulvinar

CMVPL

VPMIntCap-post

Pineal

Forebrain (oblique axial): VP/ Pulvinar, CM, Pineal

Trig

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Haines Atlas 5-32

Int. Caps.: posterior limb

Trig

Somatosensory radiations

Forebrain coronal thru Ant Thal Nu / MB

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Trigeminal System

•Lateral: near Sylvian fissure

Haines Atlas (7th ) 8- 9 Trig

Representation of face in SI

•Post to Broca area (left)