1. Systemic Lupus Erythematosus (SLE) 2. Epidemiology of SLE
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1. Systemic Lupus Erythematosus (SLE) 2. Epidemiology of SLE Tufts OpenCourseWare © 2007 Tufts University Systemic Lupus Erythematosus (SLE) OCW: Musculoskeletal Pathophysiology (R. A. Kalish) Page - 1
Transcript of 1. Systemic Lupus Erythematosus (SLE) 2. Epidemiology of SLE
1. Systemic Lupus Erythematosus (SLE)
2. Epidemiology of SLE
Tufts OpenCourseWare © 2007 Tufts University
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OCW: Musculoskeletal Pathophysiology (R. A. Kalish) Page - 1
3. Pathogenesis of SLE
4. Pathogenesis of SLE
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5. Pathogenesis – Immunologic Abnormalities
6. B cells in SLE
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7. T cells in SLE
8. Pathogenesis – Immunologic factors
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9. Observed immune abnormalities in SLE
10. Principle of IndirectImmunofluorescence
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11. Clinically relevant autoantibodies in SLE
12. Mechanism of tissue damage in SLE
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13. Clinical Features of SLE
14. Systemic Lupus Erythematosus (SLE): Slide 15
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15. Cutaneous Manifestations
16. Cutaneous manifestations
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17. Cutaneous manifestations
18. Pulmonary manifestations
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19. Cardiac manifestations
20. Hematologic manifestations
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21. Gastrointestinal manifestations
22. Neuropsychiatric (?25-50%) – Functional vs organic dif...
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23. Neuropsychiatric
24. Lupus nephritis (50%)
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25. Lupus Nephritis – clinical presentation
26. Classification of SLE with Reference to Glumerulonephritis...
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27. Treatment of Lupus Nephritis – NIH Data
28. 1982 revised criteria for classification of systemic lupus e...
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29. Management of SLE
30. Future Therapies
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