1 Macromolecules copyright cmassengale. DO NOW… 1) What does CHNOPS stand for? 2) Is Hydrogen (H)...

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1 Macromolecule Macromolecule s s copyright cmassengale

Transcript of 1 Macromolecules copyright cmassengale. DO NOW… 1) What does CHNOPS stand for? 2) Is Hydrogen (H)...

Page 1: 1 Macromolecules copyright cmassengale. DO NOW… 1) What does CHNOPS stand for? 2) Is Hydrogen (H) a molecule or an element? 3) Is Water (H 2 O) a molecule.

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MacromolecMacromoleculesules

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Page 2: 1 Macromolecules copyright cmassengale. DO NOW… 1) What does CHNOPS stand for? 2) Is Hydrogen (H) a molecule or an element? 3) Is Water (H 2 O) a molecule.

DO NOW…• 1) What does CHNOPS stand for? • 2) Is Hydrogen (H) a molecule or an

element?

• 3) Is Water (H2O) a molecule or an element?

• 4) What elements make up carbon dioxide (CO2)?

• 5) What elements make up GLUCOSE?

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Page 3: 1 Macromolecules copyright cmassengale. DO NOW… 1) What does CHNOPS stand for? 2) Is Hydrogen (H) a molecule or an element? 3) Is Water (H 2 O) a molecule.

MACROMOLECULES• Answer the first THREE questions on your

notes!

• SHARE OUT!

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Page 4: 1 Macromolecules copyright cmassengale. DO NOW… 1) What does CHNOPS stand for? 2) Is Hydrogen (H) a molecule or an element? 3) Is Water (H 2 O) a molecule.

• ATOMS COMBINE TO MAKE ELEMENTS!

• ELEMENTS COMBINE TO MAKE MOLECULES!

• WHICH ELEMENTS MAKE UP THE MOLECULE SHOWN?

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CONNECTIONS…

What connections do we have to the term “organic compounds”?

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Organic Organic CompoundsCompounds

• CompoundsCompounds that contain CARBONCARBON are called organicorganic.

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Carbon (C)Carbon (C)

• CarbonCarbon can form bondsbonds with as many as 4 4 other atoms (elements).

• Usually with C, H, O or NC, H, O or N.

PREVIOUS KNOWLEDGE: WHAT ARE THESE ELEMENTS?

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MacromoleculesMacromolecules

• Macromolecules are large Macromolecules are large organic molecules made up of organic molecules made up of smaller molecules! smaller molecules!

• Examples:Examples:THE FOUR MOLECULES OF THE FOUR MOLECULES OF

LIFE?LIFE?

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MacromoleculesMacromolecules

• Examples:Examples:1. Carbohydrates1. Carbohydrates2. Lipids2. Lipids3. Proteins3. Proteins4. Nucleic acids (DNA and 4. Nucleic acids (DNA and

RNA)RNA)

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CarbohydratCarbohydrateses

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CarbohydratesCarbohydrates

Small sugar moleculesSmall sugar molecules COMBINE to make large large sugar moleculessugar molecules.

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CarbohydratesCarbohydratesMonosaccharide: one sugar Monosaccharide: one sugar

unitunit

Example:Example: glucose (glucose (C6H12O6)

glucoseglucose

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CarbohydratesCarbohydrates

Disaccharide: two sugar Disaccharide: two sugar unitunit

Examples: Examples: – Maltose (glucose+glucose)Maltose (glucose+glucose)

glucoseglucoseglucoseglucose

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BUILD THIS MACROMOLECULE…

Voices/Movement: “Restaurant voices,” sitting still

Instructions: Using the information from your notes and the pieces of paper in front of you, build a DisaccharideDisaccharide!

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CarbohydratesCarbohydratesPolysaccharide: many sugar Polysaccharide: many sugar

unitsunits

Example:Example: cellulose (lettuce, cellulose (lettuce, corn)corn)

glucoseglucoseglucoseglucose

glucoseglucoseglucoseglucose

glucoseglucoseglucoseglucose

glucoseglucoseglucoseglucose

cellulosecellulose

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BUILD THIS MACROMOLECULE…

Voices/Movement: “Restaurant voices,” sitting still

Instructions: Using the information from your notes and the pieces of paper in front of you, build a PolysaccharidePolysaccharide!

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LipidsLipids

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LipidsLipids

Lipids are Lipids are FATSFATS! They contain ! They contain the MOST energy of any the MOST energy of any macromolecule.macromolecule.

•Example:Example: Triglyceride Triglyceride

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LipidsLipidsTriglycerides:Triglycerides:

ccomposed of 1 glycerol1 glycerol and 3 3 fatty acidsfatty acids.

H

H-C----O

H-C----O

H-C----O

H

glycerol

O

C-CH2-CH2-CH2-CH2-CH2-CH2-CH2-CH2-CH2-CH3

=

fatty acids

O

C-CH2-CH2-CH2-CH2-CH2-CH2-CH2-CH2-CH2-CH3

=

O

C-CH2-CH2-CH2-CH =CH-CH2 -CH

2 -CH2 -CH

2 -CH3

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BUILD THIS MACROMOLECULE…

Voices/Movement: “Restaurant voices,” sitting still

Instructions: Using the information from your notes and the pieces of paper in front of you, build a TriglycerideTriglyceride!

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ProteinsProteins

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Proteins Proteins (Polypeptides)(Polypeptides)

Proteins are made up of Amino acids bonded together by peptide bonds.peptide bonds.

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Primary StructureAmino acids bonded

together by peptide peptide bonds (straight chains)bonds (straight chains)

aa1 aa2 aa3 aa4 aa5 aa6

Peptide Bonds

Amino Acids (aa)

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BUILD THIS MACROMOLECULE…

Voices/Movement: “Restaurant voices,” sitting still

Instructions: Using the information from your notes and the pieces of paper in front of you, build a ProteinProtein!

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Proteins are folded into 3-dimensional shapes that are held together by hydrogen bondshydrogen bonds.•Two examples:Two examples:

Alpha HelixAlpha Helix

Beta Pleated SheetBeta Pleated Sheet

Hydrogen BondsHydrogen Bondscopyright cmassengale

Protein Structure

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Nucleic Nucleic AcidsAcids

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Nucleic acidsNucleic acids• Two types:Two types:

a. Deoxyribonucleic acid a. Deoxyribonucleic acid (DNA-(DNA- double helix) double helix) b. Ribonucleic acid (RNA-single b. Ribonucleic acid (RNA-single strand) strand)

• Nucleic acids Nucleic acids are composed of long chains of nucleotidesnucleotides.

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Nucleic acidsNucleic acids• Nucleotides include:Nucleotides include:

1. 1. phosphate groupphosphate group2. 2. pentose sugar pentose sugar 3. nitrogen bases:3. nitrogen bases:

adenine (A)adenine (A)thymine (T) DNA onlythymine (T) DNA onlyuracil (U) RNA onlyuracil (U) RNA onlycytosine (C)cytosine (C)guanine (G)guanine (G)

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BUILD THE FOLLOWING STRUCTURE:

Instructions: Using the paper in front of you, scissors and markers, BUILD AND LABEL a nucleic acid! AN IMAGE WILL BE SHOWN ON THE NEXT SLIDE!

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Nucleotide Nucleotide

OO=P-O O

PhosphatePhosphate GroupGroup

NNitrogenous baseNitrogenous base (A, G, C, or T)(A, G, C, or T)

CH2

O

C1C4

C3 C2

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SugarSugar(deoxyribose)(deoxyribose)

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DNA - double helixDNA - double helix

P

P

P

O

O

O

1

23

4

5

5

3

3

5

P

P

PO

O

O

1

2 3

4

5

5

3

5

3

G C

T A

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