1 Indian Traditional Knowledge of Health & Healing...knowledge principles using modern scientific...
Transcript of 1 Indian Traditional Knowledge of Health & Healing...knowledge principles using modern scientific...
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Indian Traditional Knowledge of Health & Healing
• Codified stream: Ayurveda, Siddha, Unani and Sowa-rig-pa (as practiced in Himalayan region) - transmitted through institutional training
• Non-codified stream: Mostly orally transmitted through family elders and teacher-disciple learning, ethnic community and ecosystem specific, empirically proven local health practices
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Transdisciplinary University
• Founded in 1994 for Revitalization of Local Health Traditions
• A National Centre of Excellence on Conservation of Medicinal Plants and Traditional Medicine
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Conservation of Medicinal Plants
• Largescale in-situ conservation for medicinal plants across 15 states in India through public-private partnerships;
• Ex-situ conservation and development of local resource and learning centres for TK
• Home herbal gardens across different states for primary healthcare
• National Databases on various aspects related to medicinal plants
• Linking healers with medicinal plant conservation and primary healthcare programs
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Traditional Knowledge
• Documentation and assessment of traditional knowledge –an innovative methodology
• Training for community health workers/healers across India
• Local pharmacopoeia-based users manuals in both human and animal health
• Documentation on specific areas like traditional bone setting, traditional birth attendants, spiritual healing, ethnoveterinary health traditions, reproductive health etc.
• People’s Biodiversity Registers and biocultural protocols
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Traditional Healers and Knowledge Holders
• Healers networks and self-regulatory mechanisms in different states
• State level and district level meetings
• Community to Community Learning Exchanges
• Accreditation and certification of prior learning
• Linking healers in developing enterprises
• Community health linkages
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Research and Development
• Research into specific public health issues like malaria, iron deficiency anaemia, water purification
• Focused strategic programs in areas like ethnoveterinary traditions
• Product development based on local innovations and promotion through community owned enterprises
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Policy Advocacy
• Policy impact in national planning processes for medicinal plant conservation and health
• National Biodiversity Law and inputs to the formulation
• Recognition of local healers in the National Health Policy
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Community to Community Learning Exchange
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Community to Community Learning Exchange
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Folk Health Practices in India
• 1 million community supported THPs
• Present almost in all 600,000 villages
• Several millions practice at the household level
• Managing a range of simple to complex conditions
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Profile of Folk Health PractitionersMillions of Knowledgeable HousewivesKnowledgeable in Home Remedies, Food and Nutrition
600000 Traditional Birth Attendants - 1 per village, skilled in Normal Deliveries
100000 Herbal Healers who manage Common Ailments @ 1 per 6 Villages
60000 Traditional bone setters - 1 per 10 Villages
60000 healers who treat poisonous bites @ 1 healer per 10 villages
Specialists in Eyes, Skin, Dental, Respiratory, Mental Diseases - 1000 in every State in Rural Communities
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Documentation by CBO members of repeatedly
used remedies from local knowledge holders
Prioritization of Health Conditions through PRA
Documentation through literature referencing on symptoms, causes
and remedies for specific conditions from codified and
indigenous systems of medicine by NGO or Ayurvedic college
Participatory Rapid Assessment of local health practices by
villagers, healers, Ayurvedic and allopathic physicians to identify
effective remedies
Training programs by
NGOs to households
Establish Community and
Home Herbal Gardens
Training by FRLHT to NGO staff, key stakeholders and CBO members on different
steps of DALHT
Prioritized list of health conditions
Data on health practices of the selected areas
References of plants used in local health
traditions for specific conditions
Remedies which are: 1 positive -> promote 2 distorted -> discard3 incomplete -> add info4. still not understood -> study further
Field trials, clinical
research & publications
Product development through local enterprises
1. Documentation and Assessment of Local Health Traditions
STEPS OUTPUTS
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2. Certification of Prior Learning of Traditional Healers
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3. Towards Creating an Innovation Platform Using Traditional Knowledge Databases
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Objectives
• Support conservation and sustainable use practices
• Rapid assessment of traditional knowledge & promotion in primary healthcare
• Defensive protection of traditional knowledge
• Drugs/therapeutic product development based on TK
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IMPLAD-Indian Medicinal Plant Database of 6500 species
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Example – Distribution maps
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DRUG DISCOVERY PLATFORM
Traditional knowledge
Systems
AyurvedaSiddhaUnaniLHTYoga
Parameters
Svastha(prakriti etc.)Environment
Food & NutritionDiagnosis & Treatment
Medicinal plantsPharmacopoea
Functional Genomics
Systems
HumanAnimals /
InsectsMicrobiome
Medicinal Plants
Parameters
Genomics Transcriptomics
ProteomicsMetabolomics
NP DATABASE
Bioactives
Targets
Disease targets
Inputs MG/VG
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Transdisciplinary studies• Research efforts to understand traditional
knowledge principles using modern scientific tools.
• Transdisciplinary approaches and methodologies to capture the holism of traditional knowledge
• New scientific perspectives and methodologies in systems biology, pharmaco- and nutri-genomics, personalized medicine, network pharmacology, etc., are better equipped to engage in a dialogue with traditional knowledge
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Differing Epistemology – A Major Challenge for ResearchAspects Modern science Traditional knowledge
1 Approach & Disease
classification system
Structural Functional
2 Location Organ Specific or Localized Systemic
3 Causality Single Causality Multiple Causality
4 Reasoning method Linear Non-linear and Circular reasoning
5 Causative reason Organism centered Immunity centered
6 Nature of knowledge Objectivity centered Subjectivity centered
7 Nature of assessment Quantitative Qualitative
8 Context Outside the context In the context
9 Diagnostic approach Universalization Individualization
10 Domains Physical (often mental), Disease centered Physical, mental and spiritual, Illness
centered
11 Treatment focus Curative focus, importance given to drugs,
surgery
Prevention focus, importance given to
drugs, food, lifestyle
12 Treatment strategy Targeted medicine Formulation concept
13 Line of treatment Treating a specific manifestation at given
time
Stage wise management
14 Outcome Effect is important Effect should not lead to after effect
15 Knowledge/practice focus Method/institution centered Individual centered
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Example - Network pharmacology
• A new paradigm for drug discovery- network pharmacology- Designer drugs
• New understanding that drug action cannot be simplified to one drug–one target–one disease theory
• More complex than a simple lock and key mechanism.
• Traditional medicine-based polyherbal formulations have been studied using -omics technologies and proposed as new strategies in drug discovery instead of single molecule-based drugs to tackle disease complexity
• Recent study of Thriphala (Patwardhan et al. 2016)
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Piper nigrum Network of 400 Bioactives and their Targets
Piperine increases bioavailability of many drugs and nutrients by inhibiting various metabolising enzymes and ‟Piperine‟‟exhibits diverse pharmacological activities like antihypertensive, antiplatelet, antioxidant, antitumor, anti-asthmatics, analgesic, anti-inflammatory, anti-diarrheal, antispasmodic, antidepressants, immunomodulatory, anticonvulsant, anti-thyroids, antibacterial, antifungal, hepato-protective, insecticidal and larvicidal activities.
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Example - Reverse pharmacology
• Reverse pharmacology is “the science of integrating bedside documented experiential observations into leads by trans-disciplinary exploratory studies and to further develop these leads into drug candidates by state-of-art experimental and clinical research”
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Learning
• Purposive, comprehensive documentation of traditional knowledge is important
• Databases need to be designed to support traditional knowledge in its holistic perspective
• New theoretical perspectives and methods to be applied for traditional knowledge research and development
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Natural resources
Knowledge resources
Human resources
Good Practices in
public health
Equity and livelihoods
Intercultural approaches
Education
Protection of knowledge
Indigenous rights
Socio-cultural landscapes
Institutionalization
Partnerships networking
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Thank you very much!