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Cell Structure and
Function
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Concepts of the Cell Theory
A cell is the basicstructural and functional
unitof living organisms.The activity of anorganism depends on thecollective activities of itscells.
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Concepts of the Cell Theory
According to theprincipleof complementarity, the
biochemical activities ofcells are dictated by therelative number of their
specic subcellularstructures.
Continuity of life has a
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Chemical Components of Cells
Most cells are composedof the following four
elementsCarbon
Hydrogen!ygen
"itrogen
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Cells and Tissues
Carry out all chemicalactivities needed to
sustain life Cells are the building
bloc#s of all livingthings.
Tissues are groups of
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Anatomy of the Cell
Cells are not all the same. All cells share generalstructures.
All cells have three main regions
"ucleus
Cytoplasm$lasma membrane
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Anatomy of the Cell
The nucleoplasm andcytosol ma#e up the
intracellular %uid.
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Nucleus
Cytoplasm
Plasmamembrane
(a)
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The "ucleus
Control center of the cellContains genetic material&'"A(
Three regions
"uclear envelope &membrane(
"ucleolus
Chromatin
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Nucleus
Nuclear envelope
Chromatin
Nuclearpores
Nucleolus
Rough ER
(b) Figure 3.1b
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The "ucleus
"uclear envelope &membrane()arrier of the nucleus
Consists of a doublemembrane
Contains nuclear pores that
allow for e!change of materialwith the rest of the cell
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The "ucleus
"ucleoli"ucleus contains one or
more nucleoliSites of ribosomeassembly
*ibosomes migrate intothe cytoplasm through
nuclear ores
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The "ucleus
Chromatin
Composed of DNA andprotein
$resent when the cell isnot dividing
Scattered throughout thenucleus
Condensesto form
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$lasma Membrane
)arrier for cell contents Double phospholipid
layerHydrophilic heads
Hydrophobic tails Also contains proteins,
cholesterol, and
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$lasma Membrane
Glycoproteins-Themolecules that ma#e the
cell surface fu++y, stic#y,and sugar-rich
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$lasma Membrane
A( it consists of two lipid layers
)( its lipid components areprimarily phospholipids and
cholesterolC( it contains proteins for
speciali+ed functions
'( it regulates the entry and e!itof cell materials
( it does not allows watersoluble molecules to ass
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Figure 3.2
Extracellular uid(watery environment)
ugargroup
Polar hea!s o"phospholipi!molecules
#imolecularlipi! layercontainingproteins
Nonpolar tails
o" phospholipi!molecules
$lycoprotein
Proteins Filaments o"
cytos%eleton Cytoplasm(watery environment)
Channel
Cholesterol
/lycolipid
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$lasma Membrane 0unctions
Membrane 1unctions2. Tight 1unctions
3. 'esmosomes4. /ap 1unctions
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$lasma Membrane 0unctions
Membrane 1unctions2. Tight 1unctions
5mpermeable 1unctions
)ind cells together into
lea#proof sheets membrane connections
that prevent the lea#ing of
%uid between cells
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Plasmamembranes o"a!&acent cells
'esmosome(anchoring
&unction)
ight(impermeable)&unction
icrovilli
$ap(communicating)
&unction
E*tracellularspace bet+een
cells
,n!erlyingbasement
membrane
Conne*on
Figure 3.3
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$lasma Membrane 0unctions
Membrane 1unctions3. 'esmosomes
Anchoring 1unctions thatprevent cells from beingpulled apart
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Plasmamembranes o"a!&acent cells
'esmosome(anchoring
&unction)
ight(impermeable)&unction
icrovilli
$ap(communicating)
&unction
E*tracellularspace bet+een
cells
,n!erlyingbasement
membrane
Conne*on
Figure 3.3
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$lasma Membrane 0unctions
Membrane 1unctions4. /ap 1unctions
Allow communicationbetween cells
Allows Nutrients andions pass directly
from cell to cell
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Plasmamembranes o"a!&acent cells
'esmosome(anchoring
&unction)
ight(impermeable)&unction
icrovilli
$ap(communicating)
&unction
E*tracellularspace bet+een
cells
,n!erlyingbasement
membrane
Conne*on
Figure 3.3
C t l
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Cytoplasm
The material outsidethe nucleus and inside
the plasma membraneSite of most cellular
activities
C t l
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Cytoplasm
Contains threema1or elements
2.Cytosol
3.rganelle4.5nclusions
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Cytoplasm
Contains three ma1orelements
2. CytosolFluid that suspends
other elements
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Cytoplasm
Contains three ma1orelements
3. rganellesMetabolic machineryof the cell
67ittle organs8 thatperform functions for
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Cytoplasm
Contains three ma1orelements
3. rganellesThe speciali+ed cellularcompartments withinthe cytosol of the cell
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Cytoplasm
Contains three ma1orelements
4. 5nclusionsChemical
substances such asstored nutrients or
Chromatin
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Ribosomes
$olgi apparatus
ecretion being release!
"rom cell by e*ocytosisicrotubule
Centrioles
itochon!rion
-ysosome
Cytosol
mooth en!oplasmicreticulum
Chromatin
Nucleolus
Nuclear envelope
Nucleus
Plasmamembrane
Roughen!oplasmicreticulum
5ntermediate
laments
$ero!isome
Figure 3.
C t l i ll
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Cytoplasmic rganelles
Mitochondria6$owerhouses8 of the cell
Change shapecontinuously
Carry out reactions whereo!ygen is used to brea#down food
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Cytoplasmic rganelles
*ibosomesMade of protein and
*"ASites of proteinsynthesis
Found at two locations
Free in the
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Cytoplasmic rganelles
ndoplasmic reticulum &*(
Fluid-lled tubules forcarrying substances
Two types of *
2. Rough endoplasmic
reticulumStudded with ribosomes
Synthesi+es proteins
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Cytoplasmic rganelles
ndoplasmic reticulum&*(
Two types of *
3. moothendoplasmic
reticulumFunctions in lipid
metabolism and
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Figure 3./
0n the cistern the protein "ol!s into its"unctional shape. hort sugar chainsmay be attache! to the protein ("orminga glycoprotein).
he protein is pac%age! in a tinymembranous sac calle! a transportvesicle.
he transport vesicle bu!s "rom therough ER an! travels to the $olgiapparatus "or "urther processing.
s the protein is synthesie! on theribosome it migrates into the rough ERcistern.
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1
Ribosome mRN
Rough ER
ransportvesicle bu!s o""
Protein insi!etransport vesicle
Protein
3
2
1
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Figure 3./ step 1
Ribosome mRN
Rough ER
Protein
s the protein is synthesie! on theribosome it migrates into the rough ERcistern.
1
1
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Figure 3./ step 2
0n the cistern the protein "ol!s into its"unctional shape. hort sugar chainsmay be attache! to the protein ("orminga glycoprotein).
s the protein is synthesie! on theribosome it migrates into the rough ERcistern.
2
Ribosome mRN
Rough ER
Protein
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1
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Figure 3./ step 3
0n the cistern the protein "ol!s into its"unctional shape. hort sugar chainsmay be attache! to the protein ("orminga glycoprotein).
he protein is pac%age! in a tinymembranous sac calle! a transportvesicle.
s the protein is synthesie! on theribosome it migrates into the rough ERcistern.
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1
Ribosome mRN
Rough ER
ransportvesicle bu!s o""
Protein
3
2
1
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Figure 3./ step
0n the cistern the protein "ol!s into its"unctional shape. hort sugar chainsmay be attache! to the protein ("orminga glycoprotein).
he protein is pac%age! in a tinymembranous sac calle! a transportvesicle.
he transport vesicle bu!s "rom therough ER an! travels to the $olgiapparatus "or "urther processing.
s the protein is synthesie! on theribosome it migrates into the rough ERcistern.
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1
Ribosome mRN
Rough ER
ransportvesicle bu!s o""
Protein insi!etransport vesicle
Protein
3
2
1
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Cytoplasmic rganelles
Golgi apparatusModies and pac#ages
proteins$roduces di9erent typesof pac#ages
ecretory vesicles
Cell membrane
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Figure 3.4
$olgi vesicle containing!igestive enymesbecomes a lysosome
Path+ay 3
Path+ay 2
ecretory vesicles
Proteins
ecretion bye*ocytosis
$olgi vesicle containingproteins to be secrete!becomes a secretoryvesicle
$olgiapparatus
Path+ay 1
ransportvesicle
embrane
Proteins in cisternaCisternaRough ER
-ysosome "uses +ith
ingeste! substances
$olgi vesicle containingmembrane components"uses +ith the plasma
membrane
Plasma membrane
Extracellular fluid
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Cytoplasmic rganelles
7ysosomesContain en+ymes
produced by ribosomes$ac#aged and secretedby the /olgi apparatus
'igest worn-out ornonusable materials
within the cell
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Cytoplasmic rganelles
$ero!isomesMembranous sacs ofo!idase en+ymes
'eto!ify harmfulsubstances such as
alcohol and formaldehyde)rea# down free radicals&highly reactive chemicals(
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Cytoplasmic rganelles Cytos#eleton
"etwor# of protein structuresthat e!tend throughout thecytoplasm
$rovides the cell with aninternal framewor#
Three di9erent types ofelements
Microlaments &largest(
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Figure 3.5a6c
(a) icro"ilaments (b) 0nterme!iate "ilaments (c) icrotubules
ctin subunit
5 nm 17 nm
Fibrous subunits ubulin subunits
2/ nm
icro"ilaments "orm the bluenet+or% surroun!ing the pin%nucleus.
0nterme!iate "ilaments "ormthe purple batli%e net+or%.
icrotubules appear as gol!net+or%s surroun!ing thecells8 pin% nuclei.
l i ll
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Cytoplasmic rganelles
Centrioles*od-shaped bodies
made ofmicrotubules
'irect the formationof mitotic spindle
C ll l 1 i
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Cellular $ro1ections
"ot found in all cells
Ciliamove materialsacross the cell surface
7ocated in the respiratorysystem to move mucus
"lagellapropel the cell
The only %agellated cellin the human body is
sperm
C ll l $ 1 i
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Cellular $ro1ections
"ot found in all cells
#icrovilliare tiny,ngerli#e e!tensions of
the plasma membrane5ncrease surface area
for absorption
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Figure 3.9a
Fibroblasts
Rough ER an! $olgiapparatus No organelles
Nucleus
Erythrocytes
(a) Cells that connect bo!y parts
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Figure 3.9b
Epithelialcells
Nucleus
0nterme!iate
"ilaments
(b) Cells that cover an! line bo!y organs
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Figure 3.9c
%eletalmuscle cell
Nuclei
Contractile
"ilaments
mooth
muscle cells
(c) Cells that move organs an! bo!y parts
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Figure 3.9!
Fat cell -ipi! !roplet
(!) Cell that stores
nutrients
Nucleus
-ysosomes
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-ysosomes
acrophage
(e) Cell that "ights
!isease
Pseu!o6po!s
Figure 3.9e
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Figure 3.9"
ProcessesRough ER
Nerve cell
Nucleus
(") Cell that gathers in"ormation an! controls bo!y "unctions
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Nucleus Flagellum
perm
(g) Cell o" repro!uction