Medical Device PartnershipsMedical Device Partnerships How Can Big Brothers and Sisters Help?

Thomas Davison, Ph.D.Thomas Davison, Ph.D.Chairman & CEO

Serial Entrepreneur = Starting companies is Serial Entrepreneur = Starting companies is the only way we can find jobs.

Most of us have management experience in Most of us have management experience in major medical device companies.

Successful entrepreneurs have extensive Successful entrepreneurs have extensive connections within major medical device companiescompanies.

J&J, Covidien, Medtronic, Boston Scientific, Abbott to name a fewAbbott … to name a few.

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Strategic Partnerships of the past 12 months

Tech Transfer Transactions◦ Co-Development with University = 1◦ University company start-up spin off = 4◦ University licenses = 12C T ti Company Transactions◦ Equity investments = 3

Product Acquisitions 5◦ Product Acquisitions = 5◦ Development Partnerships = 20◦ Product Licenses for Distribution = 46◦ Product Licenses for Distribution = 46◦ Mergers & Acquisitions = 102Data from MedTech Insight

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Data from MedTech Insight

Discuss your ideas with New Business Discuss your ideas with New Business Development execs before starting company

Start with non-confidential Exec. Summary & Start with non confidential Exec. Summary & follow with NDA for full disclosure

Potential investors Strategic opportunities or acquisition may

evolve with frequent updates Do not “plan” on strategic partnerships alone

for success in Medical DeviceM i i di i Most strategic partnering discussions or transactions lead to acquisition

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UltraCision – Ethicon Endosurgery (J&J) UltraCision – Ethicon Endosurgery (J&J)◦ Strategic partnership discussions for distribution◦ Led to acquisitionLed to acquisition

Zimmer – Endius◦ Distribution partnershipDistribution partnership◦ Led to acquisition

HistoSonics HistoSonics◦ Platform technology with numerous clinical

applications in urology. “urology company”◦ Many clinical applications outside of Urology could

lead to sublicensing and development partnerships

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Questions? Contact:Thomas Davison, PhD, Chairman/CEO , , /

tom.davison@histosonics.com or (774) 571‐9558

Thank you!

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