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Trabecular more metabolically active Bone loss leads to thinning and perforation of trabecular plates Osteoporotic fractures occur at sites with at least 50% trabecular bone

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Highlighted areas have at least 50% trabecular bone

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Peak bone density is achieved by late 20s/early 30s Bone loss after skeletal maturity is about 1% per annum in both sexes Greater loss in woman for around 3 years following menopause

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1 in 3 postmenopausal women 1 in 10 men over 50

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Primary Type 1 (postmenopausal) Type II(senile) Idiopathic Secondary Endocrine (hyperthyroidism, Cushings) Gastrointestinal (coeliac TPN Crohns) Rheumatologocal (RA ankylosing spondylites) Malignancy Drugs (corticosteroids heparin)

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DXA stands for :- Dual Energy X-Ray Absorptiometry DXA measures, it is NOT an imaging machine Measurements are taken from the axial skeleton

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Performed if either of other preferred sites are unusable or in the case of certain conditions Endocrine or gastrointestinal

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Shows body composition Used for research Occasionally used to monitor weight fat loss, muscle gain

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WHERE

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