* Plus–minus values are means ±SD. † Race was determined by the investigator.

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* Plus–minus values are means ±SD. Race was determined by the investigator. The body-mass index is the weight in kilograms divided by the square of the height in meters. § To convert values for LDL, HDL, and total cholesterol to millimoles per liter, multiply by 0.02586. To convert values for triglycerides to millimoles per liter, multiply by 0.01129. P Barter, et al. NEJM 2007;357:1301-10 The TNT HDL Study: Baseline Characteristic s of the Patients According to Quintile of HDL Cholesterol Level at Month 3*

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The TNT HDL Study: Baseline Characteristics of the Patients According to Quintile of HDL Cholesterol Level at Month 3*. * Plus–minus values are means ±SD. † Race was determined by the investigator. - PowerPoint PPT Presentation

Transcript of * Plus–minus values are means ±SD. † Race was determined by the investigator.

Page 1: *  Plus–minus values are means ±SD. †  Race was determined by the investigator.

* Plus–minus values are means ±SD.† Race was determined by the investigator.‡ The body-mass index is the weight in kilograms divided by the square of the height in meters.§ To convert values for LDL, HDL, and total cholesterol to millimoles per liter, multiply by 0.02586. To convert values for triglycerides to millimoles per liter, multiply by 0.01129.

P Barter, et al. NEJM 2007;357:1301-10

The TNT HDL Study:

Baseline Characteristics of the Patients According to

Quintile of HDL Cholesterol Level

at Month 3*

Page 2: *  Plus–minus values are means ±SD. †  Race was determined by the investigator.

The TNT HDL Study: Multivariate Analysis of the Relationship between HDL Cholesterol Levels at Month 3 and the Risk of

Major Cardiovascular Events - Results for all patients

Philip Barter, et al. N Engl J Med 2007;357:1301-10

Page 3: *  Plus–minus values are means ±SD. †  Race was determined by the investigator.

The TNT HDL Study: Multivariate Analysis of the Relationship between HDL Cholesterol Levels at Month 3 and the Risk of Major Cardiovascular

Events - Results for for the 10-mg and 80-mg atorvastatin groups

Philip Barter, et al. N Engl J Med 2007;357:1301-10

Page 4: *  Plus–minus values are means ±SD. †  Race was determined by the investigator.

The TNT HDL Study: Multivariate Analysis of the Relationship between Major Cardiovascular Events and Quintiles of HDL Cholesterol Levels

Patients were stratified according to specific cutoff points of LDL cholesterol levels in patients receiving statins

Philip Barter, et al. N Engl J Med 2007;357:1301-10

Page 5: *  Plus–minus values are means ±SD. †  Race was determined by the investigator.

The TNT HDL Study: Multivariate Analysis of the Relationship between Major Cardiovascular Events and Quintiles of HDL Cholesterol LevelsPatients in thelowest stratum of LDL-C during statin treatment (<70 mg per deciliter) were analyzed according to quintile of HDL-C level during treatment

Philip Barter, et al. N Engl J Med 2007;357:1301-10

Page 6: *  Plus–minus values are means ±SD. †  Race was determined by the investigator.

The TNT HDL Study: Relationship between Major Cardiovascular Events and Ratio of LDL

Cholesterol to HDL Cholesterol at Month 3

Philip Barter, et al. N Engl J Med 2007;357:1301-10

Page 7: *  Plus–minus values are means ±SD. †  Race was determined by the investigator.

The TNT HDL Study: Relationship between Major Cardiovascular Events and Ratio of Total

Cholesterol to HDL Cholesterol at Month 3

Philip Barter, et al. N Engl J Med 2007;357:1301-10

Page 8: *  Plus–minus values are means ±SD. †  Race was determined by the investigator.

The TNT HDL Study: Relationship between HDL Cholesterol Levels and the

Risk of Major Cardiovascular Events

Philip Barter, et al. N Engl J Med 2007;357:1301-10