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STAMPEDEComparisonOpen: Oct-2005Closed: Mar-2013Accrual: 2962
Number of patients1184 A Standard-of-care (SOC)593 B SOC + zoledronic acid592 C SOC + docetaxel593 E SOC + zoledronic acid + docetaxel
Docetaxel: Survival – M1 Patients
Robinson Cell 161:1215, 2015
23%
Mateo NEJM 373:1697, 2015
Local Therapy
Androgen Deprivation
Therapies After LHRH Agonists
and Antiandrogens
Chemotherapy
Postchemotherapy
Death
motherapa
PostchemP t hP h