80% water to 60% shrink brain & organs

Blended drink-raw Water every 3hrs-

clear Liposome creams Estrogen/

Testosterone Pregnenolone, DHEA hGH, GHRH ATP increase mental

processing Plant nitrogen

Avoid meat, dairy, toxic

Okinawa 70-100 yr Men

DHEA 2.6 DHEA 2.0ng/ml

Test 439Test 298 ng/dl

Estro 35.7Estro 12.1 pg/ml

Okinawa 70-100yrWomen

DHEA 3.0 DHEA .6

Test 13Test 39

Estro 15.5Estro 4.2

USA 70 yr men

DHEA 2.0 Test 314 Estro 20.6

USA 70 yr Women

DHEA 1.1 Test 17 Estro 5.5

Length life same, decline quality life Kyphosis- bone loss in back Very small prostate gland prepubertal Gynecomastia develops when estrogen formed by extra glandular aromatization

of adrenal androgens is sufficient to cause

breast enlargement in the face of profoundly low testosterone values

congenital growth of hair never falls out, for a eunuch never goes bald

Journal of Clinical Endocrinology & Metabolism Vol. 84, No. 12 4324-4331Copyright © 1999

120 patients: serum total testosterone did not decrease with age, sex hormone binding globulin increased significantly. Bioavailable testosterone (BT) and free testosterone decreased significantly with age, and BT and free testosterone correlated significantly with ED.

Tsujimura, A et al JOURNAL OF UROLOGY, 170 (6): 2345-2347 Part 1 DEC 2003

Testosterone- T gel replacement 100 mg/g a day improved sexual function and mood, increased lean mass and muscle strength (principally in the legs), and decreased fat mass in hypogonadal men with less skin irritation and discontinuation compared with the recommended dose of the permeation-enhanced T patch. Christina Wang The Journal of Clinical Endocrinology &

Metabolism Vol. 85, No. 8 2839-2853 © 2000

Supraphysiologic doses of testosterone, especially when combined with strength training, increase fat-free mass and muscle size and strength in normal men.Shalender Bhasin, M.D., Thomas W. Storer, Ph.D., New England J of Med, Volume 335:1-7July 4, 1996Number 1

Feb 2007 7 articles to appear in 3 journals, Am Journal Biochemistry, Journal Physiology, Journal Nutrition

Ideal Body’s own

substance

Natural to body

Adapted to the body

Side effects only when the dose is too high or too low

Synthetic Abnormal,

invented Unnatural-

Foreign Not adapted

bodyside effects

Blend (never Juice) Drink vegetables-

Bok Choy, Napa cabbage raw whole fruit-Watermelon, Frozen Cherries, berries

Cleanse 48-80 oz every morning or PM

Add Liter water Remove toxins,

cells become energized

Kudzu Extracts DIM, DMG herbs: Avena Sativa, Avena Sativa-milky

green oats, clears binding proteins (SHBG), releases Free testosterone. China carp pond fish given green oats, mated, multiplied MACA, Mucuna Pruriens, Chrysin

Female balance-Herbs-Black Cohosh

Brien Piper-using the combinations suggested on the Delgado protocol, I have reduce body fat, increased energy and mental alertness.

Sheree T. P. age 47, Weight gain, allergies, fatigue, hormone imbalance:“I have been on natural hormones, Thyroid T3, DIM to clear bad estrogens, adrenal support and elemental nitrogen for energy.I switched from juicing to Blended drinks. Now I wake up with energy till night, my skin, eyes, hair looks healthier, lost weight, hunger and craving are gone.”

Testosterone, DHT, Androstendiol

Low Androgens Excess

http://www.johnstonefitness.com

Testosterone, DHT, Androstendiol

Low Androgens Excess

DHT and Testosterone is critical for erections

Avoid Fin astride since in clears the whole body of DHT-Dihydrotestosterone, which is necessary for good erections.

It is best if you want to avoid hair loss to use a shampoo 3 times a week with DHT blockers, spirolactin, DIM to clear estrone’s in the scalp of head.

Take Estroblock to improve estrogen ratios

Dry eyes, dry skin Poor resistance to

noise Anxious look Lack feeling of well-

being Decreased pubic hair,

Loss hair under arm Cellulites, atrophy

muscle face Arlt, Wiebke, JCEM 83: 1998,

84:1999, Morales 1994

Low

Excess

Low since childhood

Low since adulthood

Excessive since adulthood

Start with multiple low dose hormones Use oral GHRH sublingual approved

delivery Inject under skin only .01 to .02 mg, some

obese individuals might use .05 to .15 mg In two months overdose can cause

bloating, enlarge limbs, tingling arms and face

Stability of GH Powder mix liquid stated to last only 2 wks, however after three months mix was sent to lab 99% of GH was still present

Vitamin B-12 Insulin hGH

1,700 mw 5,800 mw 22,000 mw

GHRH

5,000 mw

Albumin: 66,000 mw

Collagen: 50,000 – 250,000 mw

Cell Membrane

polymer + hGH Complex

Insulin GH IGF Proteins Let In By Polymer Complex MPS At Cell Surface

Use of human GH in elderly patients with accidental hip fracture

Over 75 years old, IGF returned to 50 year old level

Using GH Return to pre-fracture living: 94 vs. 75%

Van Der Lely et al.. Eur J Endocrinol 2000 Nov;143(5):585-592

Double blind, neither the doctor or patient know who was getting the real Growth hormone, 6 weeks

Plant protein, Low Meat, No Dairy, exercise

Symptoms low Cortisol: Runny nose, sore

throat, sneezing, allergies, flu

Arthritis Mental clarity

Mastorakos G, Sakkas EG, Xydakis AM, Creatsas G. Pitfalls of the WHIs: Women's Health Initiative, Ann N Y Acad Sci. 2006 Dec;1092:331-40.

Cox D. Should a doctor prescribe hormone replacement therapy which has been manufactured from mare's urine? J Med Ethics. 1996 Aug; 22(4): 199-203.

Moskowitz D. A comprehensive review of the safety and efficacy of Bioidentical hormones for the management of menopause and related health risks. Altern Med Rev. 2006 Sept; 11 (3):208-223.

What are Bioidentical hormones? Natural. Bioidentical. Compounded. Confusion about these terms is only adding to the confusion over hormone therapy. Harvard Women’s Health Watch. 2006 Aug;13 (12):1-3.

Curcio JJ, Smolinski D, Dye J. A review of bioidentical hormones, Menopause. 2005 Nov-Dec;12(6):774-5.

Walker CR. Bioidentical hormone replacement therapy. A natural option for peri-menopause and beyond. Adv Nurse Pract. 2001 May; 9 (5):39-42, 45.

Clark JH. A critique of Women's Health Initiative Studies (2002-2006). Nucl Recept Signal. 2006 Oct 30;4:e023.

Ito K. Hormone Replacement Therapy and Cancers: The Biological Roles of Estrogen and Progestin in Tumorigenesis are Different between the Endometrium and Breast. Tohoku J Exp Med. 2007 May;212(1):1-12.

Granger, Schwart, Booth, Curran, Zakaria, Assessing dehydroepiandrosterone -DHEA in saliva: a simple radioimmunoassay for use in studies of children, adolescents and adults. Psychoneuroendocrinology. 1999.

Ultimate Medical Research. Com GMP facilities Good Manufacturing Practices

Hot flashes, sweats, vaginal dryness, foggy thinking, depression, insomnia, bone loss, pains, yeast infections, body hair, memory loss, hair loss top head

Testosterone-dry thin skin, wrinkles, gray hair, diabetes, muscle loss, fatigue

Loss libido, lack endurance Rebecca Glaser MD, Hertoghe MD

Signs of poor biochemistry, insulin, estrogen, Cortisol, ACTH: Increased body fat, baldness,

bruise easily, moonfaced, swollen breast, acne

Impotency 85% - 80 yrs Prostate enlargement in 75% men by age 50, cancer by 75 Male aging study: Journal of Urology

94; 151; 54-61

Treat: Biochemistry, Fitness, Diet, Mind

--- Balding, Obese, enlarged Prostate, impotent

0

5

10

15

20

25

TestosteroneInjection

NoReplacement

Testosteronepatch

Arousal

Desire

# ofErectionsper hour xduration andrigidity

Arver S, et al, Improvement of Sexual Function in Testosterone Deficient Men Treated for 1 year with ….testosterone transdermal system. J Urology 1996;155:1604-1608

Courtesy Dr. Hertoghe

Use of Estrogen increases SHBG and Free Estrogen, which reduces availability of Androgen

Dilute “concentrated” estrogens-E1, E2, E3

Urine 16aOHE/2OHE Restore Testosterone

Use DIM, Chrysin, Avena Sativa, Androstendiol

Restore Progesterone

Low since birth Ideal Excessive

Female PMS, breast swelling, fibrocystic Breast, uterine, ovarian fibroids

Breast cancer, uterine cancer Craving sweets, weight gain, acne water retention Swollen belly, limbs Heavy, irregular menses, abdominal

pain Sleep disturbances, insomnia

0

2

4

6

8

10

12

14

16

18

20 yrs 40 60 80 100

EstradiolEstrone

DIM, INDC3

Crucifers released from crushing, chewing and digestion of raw broccoli, Bok Choy, cauliflower, Brussels sprouts

Extract DIM (Diindolylmethane) requires fatty acids to be absorbed efficiently.

DIM is related to the structure of tryptophan, serotonin, melatonin

DIM does not limit estrogen activity in the brain, and does not decrease estrogen production, it safely clears metabolites

2 caps DIM IC3 equals 2 pounds raw vegetable

DIM (Diindolylmethane) has proven beneficial to restore good estrogens -2 OHE. It clears undesirable 16 aOHE estrogens and toxin. DIM comes from cruciferous vegetables and it is nearly 10 times more potent than Idole-3-Carbinol. Yet I3C with TMG, DMG helps clear 4 Methyoxyestrone. Add with raw veggies

D-Glucuronolactone and Calcium D-Glucarate (US patent) are extracted from oranges, spinach, carrots, and apples. These extracts clear harmful 4 –methoxyestrone, bacteria and toxins (drugs, poisons, cosmetics) in the colon and improve energy flow and a sense of feeling good.

DIM & Chrysin-improves the firmness of the body by balancing biochemistry of testosterone and SHBG.

Testosterone cream 1% (10 mg/g) used 3 to 5 days a week

Use SF cream Androstendiol, DHEA, Pregnenolone daily, rubbed into Perineum vaginal area, and neck, arm.

Estroblock 2 to 4 capsules daily balance 2.5 mg Estradiol, Estriol 20 mg

progesterone compounded 100-200 mg

Pellet implant Estradiol 100mg Pellet Testosterone 50mg

Ideal body weight to lean composition

Energy and sense of wellbeingLower risk of cardiovascular diseaseImproved intimate feelings of loveMental clarity and zest for lifeSkin and organ healthImmune system

DHEA 40 to 450 Blood testosterone 438 to 1,500DHT 9-57 368- reduce to 38

PSA 3 –healthy prostate-Morgentaler A, Prevalence of prostate cancer

among hypogonadal men with prostate-specific antigen levels of 4.0 ng/ml or less. Urology 2006 Dec; 68(6):1263-7.

Growth Hormone as measured byIGF 95 improved to 350

Those that don’t respond to cream or inject Pellet last 4-6 mo

Less Insomnia better sleep

Sex Drivelibido

Blood vessel strength

Mood-anti depress

Energy Sexerectile

Bone Density

Low risk cancer

muscle fitness Skin less wrinkles

Improve immune

Less body fat

date since 1938

Hair growth

Deep sleep- Relax body & Mind, Dark room, Melatonin Sublingual

Bright day Cortisol

HGH Low dose Transdermal

Androgens Testosterone and

GH is at its highest- 4 to 6am.

Best time to make love for men is morning

Cream/drops DHEA, Pregnenolone, Testosterone, DIM, Chrysin, Avena Sativa

Female add to cream progesterone, E3-Estradiol, Estriol-E2,

Thyroid Iodine 300 mcg, L-Tyrosine, Zinc-30mg, Thyroid glandular T3-8 mcg, T4-38 mcg

Cortisol-Isocort 2.5 mg x 4= 10 mg, cortisone time release 20 mg/Cortef 5 mg x 3

HGH inject ½ iu .2mg, GH factor, insulinMelatonin spray .1 to .5 mg night Aldosterone, dopamine, nitrogen, MSH Anti aging Medical News 2006- Delgado

Ideal Lab levels IGF1, serum 310 ng/ml Testosterone, Total 1232 ng/ml (range 500 up) Testosterone, Free 26 pg/ml (20 up) DHT 38 pg/ml (20 to 57) SHBG 28 nmol/L (18 to 80) Estradiol 33 pg/ml Estrone 26 pg/ml (15 to 60) Prolactin 11 ng/ml (3 to 22) PSA 3 (0 to 4) Insulin 3 (2 to 10) Free T3 2.9 pg/ml (1.8 to 4)