Semple-PMSE.519-ACS Denver
ChemInform Abstract: Potent and Selective Thrombin Inhibitors Featuring Hydrophobic, Basic P3-P4-Aminoalkyllactam Moieties.
ChemInform Abstract: Guanylpiperidine Peptidomimetics: Potent and Selective Bis-Cation Inhibitors of Factor Xa.
ChemInform Abstract: Novel, Potent and Selective Chimeric FXa Inhibitors Featuring Hydrophobic P1-Ketoamide Moieties.
ChemInform Abstract: Non-Covalent Thrombin Inhibitors Featuring P3-Heterocycles with P1-Monocyclic Arginine Surrogates.
Non-covalent Thrombin Inhibitors Featuring P3-Heterocycles with P1-Bicyclic Arginine Surrogates.
Efficient construction of novel quaternary lactam dipeptide surrogates
Design and construction of novel thrombin inhibitors featuring P3–P4 quaternary lactam dipeptide surrogates
JMC 1996 39 4531LactamSulf
HCV Overview Boceprevir & Thiazolides JES_mod062116
Semple et al 2016 J Poly Sci_Part_A__Polymer_Chemistry
Semple et al. TZD SAR in HBV 2011 J Med Chem
JES DuPont & Shell Ag Chem Overview 0616
Semple et al. TZD SAR in HCV 2011 J Med Chem
MCR
BMCL P1Bicyclic Arg Surrogates
