Week of March 30, 2009

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Cytopathology Challenge Weekly Cases. Week of March 30, 2009. 17 year old female. Conventional pap Endocervical adenocarcinoma in situ Benign endometrial cells Viral changes consistent with Herpes Alternaria Trichimonas. 1. 17 year old female. Conventional pap - PowerPoint PPT Presentation

Transcript of Week of March 30, 2009

Week of March 30, 2009

17 year old female. Conventional papA. Endocervical adenocarcinoma in situB. Benign endometrial cellsC. Viral changes consistent with HerpesD. AlternariaE. Trichimonas 1

17 year old female. Conventional papC. Viral changes consistent with Herpes This picture is slightly out of focus;

however, you can still see the molding and margination of the nuclei c/w herpes 1

2

69 year old male. FNA of LungA. GranulomaB. Non-small cell carcinomaC. Small cell carcinomaD. Reactive bronchial cellsE. Lymphoma

2

69 year old male. FNA of LungB. Non-small cell carcinoma – The

cluster is cohesive with large pleomorphic cells. The cells are overlapping and disorganized.

3

57 year old male. Urine cytologyA. Polyoma virusB. Reactive urothelial cellsC. High grade TCCD. Metastatic prostate carcinomaE. This picture is horrible…I can’t

tell.

3

57 year old male. Urine cytologyC. High grade TCC -- Though this

picture is horrible (much like the pictures on the test), you can tell this is high grade TCC. The cells are enlarged (compared to the polys) with irregular nuclear membranes, eccentric nuclei and dark/irregularly distributed chromatin.

4

67 year old male. History of prostate carcinoma and squamous cell carcinoma of the lung. Now presents with bone pain. FNA of bone lesion

A. Positive for tumor - AdenocarcinomaB. Positive for tumor - SCCC. Plasma cell neoplasmD. Positive for tumor – LymphomaE. Positive for tumor - melanoma

Diff Quick Pap

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67 year old male. History of prostate carcinoma and squamous cell carcinoma of the lung. Now presents with bone pain. FNA of bone lesion

A. Positive for tumor – Adenocarcinoma The cells are cohesive with vague formation of

acinar structures (seen in DQ). The monomorphic appearance of the cells along with the prominent nuclei favors prostate adenocarcinoma. Melanoma is in the differential; however, melanoma cells are usually more discohesive. Immunostains can always be done to help with the diagnosis.

Diff Quick Pap

5

34 year old female. Thin Prep PapA. LSILB. Squamous metaplasiaC. Benign endocervical cellsD. HSILE. AIS

534 year old female. Thin Prep PapD. HSIL

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60 year old male. BALA. AspergillusB. BlastomycosisC. PCPD. A and BE. A and C

6

60 year old male. BALE. A and C – This is a case of

Aspergillus and PCP together.

7

51 year old female with extensive bilateral lung infiltrates. A BAL shows numerous amorphous globules as seen here. What stain should be ordered to confirm the diagnosis?

A. Silver stain (GMS)B. PASC. Iron stainD. Oil Red OE. Reticulin

PAP

7

51 year old female with extensive bilateral lung infiltrates. A BAL shows numerous amorphous globules as seen here. What stain should be ordered to confirm the diagnosis?

B. PAS – PAS will confirm the diagnosis of Pulmonary Alveolar Proteinosis.

PASSurgical

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41 year old female with newly developed breast mass. Breast FNA

A. Positive for breast carcinomaB. Phyllodes tumorC. FibroadenomaD. Consistent with breast cystE. Reactive ductal cells

8

41 year old female with newly developed breast mass. Breast FNA

C. Fibroadenoma

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29 year old female. ThinPrep pap

A. ReactiveB. Squamous metaplasiaC. ASC-USD. LSILE. HSIL

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29 year old female. ThinPrep pap

D. LSIL