Post on 20-Jan-2021
Advanced Genetics Minilecture 2: Gene Expression and Regulation
I. A brief review of gene expression
http://www.nature.com/scitable
II. Gene Regulationa. Chromatin Structure and Gene Expression
i. Chromatin Structure
ii. Epigenetic Modifications1. Cytosine Methylation
https://www.caymanchem.com/article/2153
2. Histone modificationsa. Acetylation
https://en.wikipedia.org/wiki/Histone_acetylation_and_deacetylation
b. Methylation
https://www.shmoop.com/dna/dna-packaging.html
https://www.slideshare.net/somannaan/gene-silencing-by-histone-modification
https://www.youtube.com/watch?v=hgYMgNrr7mQ
b. During Transcriptioni. Prokaryotes: The Lac operon
ii. Eukaryotes: Combinatorial Control
c. During Splicing
d. Regulation of Translation
e. Spatial Translation
f. Post-translational modifications to proteins