Veterinary Scholars Summer Research Program

1

2013 VSSP Participants Scholar Mentor Research Project Scholar Mentor Research Project

Kirsten Becker Randy Basaraba

NIH: Effects of iron chelation on monocyte metabolism; changes in CD-36 and GLUT-1 expression

Kristin Freund Nicole Ehrhart

NIH: Quantum dot labeling of canine mesenchymal stromal cells for longitudinal visualization

Jeret Benson Craig Webb

MAF: Quantitative comparison of advanced glycation end-products in the serum of diabetic to non-diabetic cats

Madeline Fujishiro Mike Lappin

YIA: Administration of intranasal Bordetella bronchiseptica vaccine and a subcutaneous FVRCP vaccine is superior to subcutaneous FVRCP vaccine alone in a FHV-1 challenge model

Julia Bromberek Paul Morley

AHA: Does exercise-induced pulmonary hemorrhage affect career longevity and performance among South African Thoroughbred racehorse

Nina Garbino Ed Hoover

NIH: Rapid in-vitro assay to detect CWD prions in deer saliva

Amy Casali Mary Jackson

Merial: Amoebal models of Non-Tuberculosis Mycobacteria (NTM) infection

Meghan Gibas Francisco Olea-Popelka

USDA: High variability in the risk estimates of zoonotic tuberculosis

Mandy Crouch Gerry Bouma

Merial: LIN28 in Exosomes Secreted by Human Placental Cells and Ovarian Cancer Cells

Lauren Hamil Jamie Custis

Merial: An analysis of radiation dose distribution following the administration of electronic brachytherapy to the canine nasal cavity

Kaitie Dozier Jeff Wilusz

NIH: Could the inhibition of the cellular decay machinery contribute to the pathogenicity of bovine viral diarrhea virus infections?

Elizabeth Hoaglund Glenn Telling

Merial: Robotically improving accuracy of the cervid prion cell assay (CPCA) method

Jessica Felgenhauer Steve Dow

Merial: Mesenchymal Stem Cell Immune Modulation of Canine Lymphocyte Responses

Cindy Hong Gabi Landolt

USDA: In vitro susceptibility of human influenza A and B viruses to nitazoxanide and tizoxanide

Genevieve Forster Elizabeth Ryan

CVMBS: Modulation of Canine Gut Hormones with Bean Consumption and Weight Loss

Sam Johnson Colleen Duncan

USDA: Degenerative and infectious change in heart valves from Northern Sea Otters

Veterinary Scholars Summer Research Program

2

2013 VSSP ParticipantsScholar Mentor Research Project Scholar Mentor Research Project

Elena Kaplan Anne Avery

AHA: Phenotype and origin of canine indolent T cell lymphoma/ leukemia

Katelyn Schermerhorn Anne Avery

Merial: Characterization of T-zone lymphoma cells

Jon Lee Gregg Dean

NIH: Quantitative measurement of bacterial 16s rRNA genes in plasma of FIV infected cats

Kat Stutzman-Rodriguez Sue VandeWoude

AHA: Novel gammaherpesviruses in mountain lions and domestic cats: variations in prevalence and predictor variables

Bree Loughridge Chris Kawcak

CRC: Deaths related to musculoskeletal injury peak mid racing season in Colorado racehorses

Lily Ngai Karsten Hueffer (UAF)

UAF Veterinary Scholar: Use of filter paper to quantify polychlorinated biphenyl (PCB) in bottlenose dolphins whole blood

Derek Matthews Chris Orton

NIH: Evidence for endothelial to mesenchymal transition in canine degenerative mitral valve disease

Meagan Nakamoto Mike Lappin

YIA: Prevalence of zoonotic parasites in shelter dogs in Veracruz, Mexico

Heather Newett Torsten Eckstein

USDA: Evaluation of Live Bp82 Vaccination Efficacy in Goats

Caitlyn Romero Christine Olver

Merial: The effects of pathogen reduction technology on malaria (Plasmodium falciparum) in whole blood units

Samantha Salmon Melinda Frye

Merial: Dietary fatty acids do not predict insulin resistance in the presence of similar body weight and visceral adiposity

Veterinary Scholars Summer Research Program

3

2014 VSSP Participants Scholar Mentor Research Project Scholar Mentor Research Project

Roxanne Benally Steve Dow

NIH: Mesenchymal Stem Cell Responses to Activation With TLR Ligands

Bernadette Loomis Valerie Moorman

Colorado Racing Commission: Precision of a Horse-Mounted Inertial Sensor Device Following Re-Application

Leigh Browning Anne Avery

Merial: Measuring cytokine production in blood from healthy dogs compared to dogs with T cell lymphoma

Bree Loughridge Chris Kawcak

Colorado Racing Commission: CT reveals higher bone density at the distal articular surface of racehorses with third metacarpal fractures

Emily Bryan Rebecca Ruch-Gallie

AHA: Prevalence of Dirofilaira Immitis in non-endemic Northern Colorado animal shelters

Kyle Martin Felix Duerr

MAF: Canine Gait Analysis Using Inertial Measurement Units During Outdoor and Treadmill Activity

Meg Gibas EJ Ehrhart

NIH: Development of an Immunocytochemistry Mast Cell Tumor profile

Daniel Moezzi Gabi Landolt

Merial: Antiviral resistance development of human-lineage influenza A viruses against Tizoxanide and Oseltamivir Carboxylate

Belen Hernandez Dawn Duval

NIH: Survey of Whole Exome Sequence Data of Canine Bladder Transitional Cell Carcinomas

Lily Ngai Rebecca Ruch-Gallie

AHA: Fecal cortisol and other measures of stress before and after clicker training cats in two Colorado animal shelters

Ellie Howe (RDSVS) Rushika Perera

Edinburgh Exchange: Inhibition of glycolysis and the TCA cycle alters dengue virus infection

Alex Pyuen Doug Thamm

Merial: In Vitro Effects of PI3K/mTOR Inhibition in Canine Hemangiosarcoma

Makenzie Kurth Gerry Bouma

NIH: Relationship between Androgen Receptor (AR) and LIN28A in the mouse placenta

Samantha Salmon Melinda Frye

AVMF: The effect of docosahexaenoic acid (DHA) on cardiac myocyte adiponectin protein expression

Emma Lantz Craig McConnell

USDA: Assessing pain and trauma in early lactation dairy cattle

Kaitlin Sholder Anne Avery

Clinical Immunology: Flow cytometric detection of canine B cell lymphoma subtypes

Naomi Lee Greg Amberg

Merial: L-type Ca2+ channel knock-out model in αT3-1 cells using the novel CRISPR-Cas9 system with gRNA

Olivia Shoup (OK St) Stu Tobet

Merial: Long-term behavioral consequences of fetal glucocorticoid excess

Veterinary Scholars Summer Research Program

4

2014 VSSP Participants Scholar Mentor Research Project Scholar Mentor Research Project

Arik Smith Shane Hentges

NIH: Anorexigenic neuron activity reflects natural feeding patterns

Theresa Wendland Felix Duerr

YIA: Evaluation of gait patterns in dogs: the pace

Brian Smith Lon Kendall

ASLAP: Comparison of sustained-release formulations of buprenorphine to buprenorphine HCl in guinea pigs

Jonathan Yashari Felix Duerr

YIA: Evaluation of a novel canine activity monitor for at-home physical activity analysis

Kat Stutzman-Rodriguez

Sue VandeWoude

NIH: Detection of antigenic proteins of Felis catus gammaherpesvirus 1

Amanda Zellar Dick Bowen

NIH: H7N9 Influenza A virus Transmission in a Model Wet Market

Sarah Therio Christine Olver

Merial: Iron dysregulation is evident in canine hemangiosarcoma: preliminary studies

Jennifer Hafferman Arleigh Reynolds (UAF)

UAF Veterinary Scholar: The effects of conditioning and daylength on Vitamin D levels in Alaskan sled dogs

Brie Trusiano Melinda Frye

Merial: The effects of docosahexaenoic acid (DHA) on cardiac microvascular endothelial cell adiponectin production

Kelsey McClure Kelly Drew (UAF)

UAF Veterinary Scholar: Brain regions involved in seasonally dependent A1 adenosine receptor agonist-induced torpor

Mandy van Koppen (Utrecht Univ)

Mike Lappin

Merial International: Prevalence of Cyclospora spp. in feces of cats in Colorado

Rachel Wanty Francisco Olea-Popelka

Merial: Effect of Azaperone on Blood Pressure in Immobilized Bull Elephants in Kruger National Park, South Africa

Daniel Wegenast (Texas A&M)

Lon Kendall

ASLAP: Evaluation of a sustained-release formulation of buprenorphine and its analgesic effects in a post-laparotomy mouse model

Veterinary Scholars Summer Research Program

5

2015 VSSP Participants Scholar Mentor Research Project Scholar Mentor Research Project

Libby Boesen Elizabeth Ryan

Merial: Effects of a bean-based diet on gut hormones in dogs undergoing short term and long term weight loss

Mariel Knox Chris Allen

NIH: DNA damage response signaling inhibition differentially affects canine osteosarcoma cell radiosensitivity

Edward Cheng Nicole Ehrhart

NIH: Influence of bone protein vaccine on macrophage recruitment and healing following allograft reconstruction of a massive bone defect Isabella Lowery Terry Spraker

Foundation: Histological features of California Sea Lion pups from the 2014-2015 die off of pups from San Miguel Island California

Teresa Garcia EJ Ehrhart

MAF: Characterization of FGFR1 and FGFR2 in Canine Osteosarcoma Tumors and Cell Lines

Kaitlyn McNamara Steve Dow

NIH: Differentiation of canine induced pluripotent stem cells into neural progenitor cells

Emily Hein Kelly Santangelo

NIH: A high fat diet versus regular chow drives an inflammatory cytokine profile in fat depots in obese guinea pigs

Emily Milchling (UPEI) Laurie Goodrich

ASLAP: An analysis of growth factor concentrations in rabbit Platelet Rich Plasma (PRP) intended for accelerated ligament healing

Belen Hernandez Dawn Duval

Merial: Analysis of genetic mutations in canine bladder transitional cell carcinomas

Steven Murray (NCSU) Angelo Izzo

ASLAP: Lactate dehydrogenase isozymes as biomarkers for the progression of tuberculosis infection in guinea pigs

Dana Hill Sushan Han

Merial: Preliminary investigation of overgrown hooves in Colorado cervids

Iris Pepping Kevin Haussler

Merial International (Netherlands): Neck pain in sport horses: what does diagnostic imaging tell us?

Stacey Hunvald Amanda Guth

NIH: Novel immunotherapy utilizing cancer stem cell targeted vaccine for improved immune system control of cancer

Stephanie Porter Dick Bowen

USDA: Experimental infection of horses and sheep with MERS coronavirus

Marta Hura Ryan Ferris

Colorado Racing Commission: The Use of Equine Bone-Marrow Derived Stem Cells as a Potential Treatment Against Preformed Biofilms

Tyler Sedam Randy Basaraba

NIH: Inflammatory response to advanced glycation end products in the murine subcutaneous air pouch model

Mark Jeon Doug Thamm

NIH: Evaluation of antineoplastic effects of JQ1 and structural analogs against a panel of canine lymphoma-derived cell lines

Arik Smith Shane Hentges

Merial: The neural regulation of feeding: anorexigenic circuits

Veterinary Scholars Summer Research Program

6

2015 VSSP ParticipantsScholar Mentor Research Project

Stephanie Smith Craig Webb

Foundation: In vitro evaluation of the effects of pre-conditioning on female canine adipose-derived mesenchymal stem cell cytokine production

Eliza Stout Francisco Olea-Popelka

USDA: Detection of tuberculosis antibodies and clinical signs in lions in Kruger National Park, South Africa

Clint Walker (LSU) Lon Kendall

ASLAP: Cationic liposome oligonucleotide complex adjuvant produces antibodies with minimal side effects in rabbits

Kelly Cunningham Todd O’Hara (UAF)

UAF Veterinary Scholar: Mercury and selenium partitioning in Steller sea lion blood compartments

Vanessa Schilling Lorrie Rea (UAF)

UAF Veterinary Scholar: Reference ranges in blood hematology in the Alaskan sled dog

Veterinary Scholars Summer Research Program

7

2016 VSSP Participants Scholar Mentor Research Project Scholar Mentor Research Project

Troy Cabral Randy Basaraba

Merial: Improving Adjunctive Treatment of Drug Resistant Diabetic Foot Infections

Ruby Jong Sue VandeWoude

Merial: Prevalence of feline coronavirus in a specific pathogen-free cat colony

Kelly Cunningham Susan Bailey

NIH: Improving Radiation Risk Assessment: a case study on wildlife species in Fukushima

Anisha Kumar Yvette Nout-Lomas

USDA: Ataxic Horses Display Quantifiable Gait Abnormalities Determined By Videography

Ross Cutcliffe Amanda Guth

NIH: Cancer Stem Cell-Targeted Vaccine Induces Antibodies Against Conserved Vaccine Antigens

Tanya Lyakhova Mary Jackson

NIH: Soil-borne protozoans enable persistence of facultative intracellular pathogens in the environment

Emmanuelle Furst Shane Hentges

NIH: Primary neuron culture autapses as a model for investigating opioid receptor desensitization

Zachary Millman Anne Avery

NIH: Validating the Cell of Origin of Canine T-Zone Lymphoma

Teresa Garcia Christie Mayo

USDA: Phylogenetic analysis of bluetongue virus field strains collected from Colorado cattle

Laurel Myers Tony Schountz

Merial: Characterizing infection of Jamaican fruit bats with bat-derived influenza-like viruses, H17N10 and H18N11

Rebecca Hoffman Sue VandeWoude

YIA: Vaccine-induced anti-receptor antibodies inhibit FIV replication in vitro

Stephen Pannone Kelly Santangelo

NIH: Evaluation of systemic injections of mesenchymal stem cells for symptom modification of primary osteoarthritis in a rodent model

Jacquelyn Hunter Mark Stenglein

NIH: Metagenomic sequencing analysis of Ixodes scapularis virome

Stephanie Porter Richard Bowen

Foundation: Environmental Reservoirs of Francisella tularensis: Mechanisms for Transmission of Tularemia

Ashley Iodence Felix Duerr

MAF: Use of Pressure Mapping in Quantitative Analysis of Pressure Points Induced by External Coaptation in Dogs

Alyssa Strumpf Steve Dow

NIH: Antimicrobial properties of human mesenchymal stem cells

Tyler Johnson Christine Olver

Merial: Coagulopathy in Crotalus viridis envenomation, attenuation by carbon monoxide releasing molecule – 2 in vitro

Marjan van den Hoogan Kevin Haussler

Merial International (Netherlands): Development of a canine functional questionnaire assessing rehabilitation outcomes

Veterinary Scholars Summer Research Program

8

2016 VSSP ParticipantsScholar Mentor Research Project

Kris Galang (OSU) Lon Kendall

ASLAP: Marble Burying for Assessing Postoperative Pain in Rats Treated with Meloxicam or Sustained-Release Meloxicam

Robert Onaga (Cornell) Lon Kendall

ASLAP: Marble Burying for Assessing Postoperative Pain in Rats Treated with Meloxicam or Sustained-Release Meloxicam

Paul Chavez Karsten Hueffer (UAF)

UAF Veterinary Scholar: Investigation of routes of transmission for a novel Neisseria species in avian eggs

Jenny Kahabka Maggie Castellini (UAF)

UAF Veterinary Scholar: Comparison of Alaskan wildlife blood samples: an analysis of zoonotic disease antibody titers and Mercury/ Selenium levels

Veterinary Scholars Summer Research Program

9

2017 VSSP Participants Scholar Mentor Research Project Scholar Mentor Research Project

Lauren Bracchi Edward Hoover

Georgia Norris Foundation Veterinary Scholar: Lympoid Cell Infection During Early Prion Disease

Michelle Evans Richard Bowen

NIH Fellowship Grant Trainee: Transmission of chikungunya virus between mosquitoes and ectothermic vertebrates within an artificial ecosystem

Holly Grams-Johnson Amy MacNeill

Boehringer Ingelheim Veterinary Scholar: Characterization of the cellular immune response of solid canine tumors to recombinant myxoma virus

Kyrie Ivanovich Brian Foy

NIH Fellowship Grant Trainee: Control of mosquito-borne pathogens using endectocidal drugs and anti-vector vaccines

Sarah Kechejian Sue VandeWoude

Boehringer Ingelheim Veterinary Scholar: Ecology of feline foamy virus infection in pumas (Puma concolor)

Alana Kuzmik Paul Avery

NIH Fellowship Grant Trainee: Further characterization of canine small B cell lymphomas

Laurel Krause Mike Lappin

Boehringer Ingelheim Veterinary Scholar: Evaluation of an in clinic test for detection of Leptospire spp. antibodies in cats

Zachary Osterholz Mark Stenglein

NIH Fellowship Grant Trainee: Tick transmission of arenaviruses and bunyaviruses

Norine Ornellas-Walsh Candace Mathiason

Boehringer Ingelheim Veterinary Scholar: Developing an immunologic profile of normal mouse placenta on day 18.5 of pregnancy

Maggie Rollert Kate Freeman

NIH Fellowship Grant Trainee: Using a sentinel species to model cataract effects of ionizing radiation in Fukushima

Morgan Pearson Gregg Dean

Boehringer Ingelheim Veterinary Scholar: Determining correlates of protection against feline enteric coronavirus infection

Meredith Scarborough Susan Bailey

NIH Fellowship Grant Trainee: Telomeres and varying lifespans in a range of rodent species

Natalia Gil Mike Lappin

Nestle Veterinary Scholar: Effect of a probiotic (Enterococcus faecium SF68) on cats with CKD

Lydia Smith-Osborne Gregory Amberg

NIH Fellowship Grant Trainee: Visualization of calcium and oxidant signaling proteins in dopaminergic neurons

Jennifer Schefski Christine Olver

Morris Animal Foundation Scholar: Interaction of canine fibrinogen with Crotalus venom/Mitigation of snake envenomation using an alternative therapy on canine whole blood exposed to hemotoxic venom

Keira Sztukowski Seonil Kim

NIH Fellowship Grant Trainee: Molecular pathways underlying Feline immunodeficiency virus (FIV)-induced neuropathology

Veterinary Scholars Summer Research Program

10

2017 VSSP Participants Scholar Mentor Research Project Scholar Mentor Research Project

Claire Hovenga Mike Lappin

PetSmart Charities Summer Scholar: Assessment of a stress relieving diet on prevalence of upper respiratory disease and diarrhea in cats housed in a shelter Mark Parlier Mark Stenglein

Boehringer Ingelheim Veterinary Scholar: Seroprevalence of Reptarenaviruses in Captive Snake Populations and Possible Vectors

Amy Zug Mike Lappin

PetSmart Charities Summer Scholar: Assessment of an immunomodulator on the duration of signs of URI in shelter dogs and cats

Elizabeth Stietzle Lon Kendall

Laboratory Animal Fellowship Trainee: Mirtazapine use in Guinea Pigs

Lauren Eytalis Ryan Ferris

USDA Animal Health & Disease Scholar: Incidence of uterine bacterial contamination, biofilm, and latent bacteria following breeding in the horse

Alexis Allen Lon Kendall

Laboratory Animal Fellowship Trainee: Identifying humane endpoints in infectious disease studies

Anthony Franceschelli Yvette Nout-Lomas

USDA Animal Health & Disease Scholar: Using Inertial Measurement Units to assess gait deficits induced in the horse by blindfolding and walking with the head elevated.

Ian Niu Lon Kendall

Laboratory Animal Fellowship Trainee: Pain assessment in rats

Elle Holbrook Christie Mayo

USDA Animal Health & Disease Scholar: Genetic characterization and comparative genome analysis of vesicular stomatitis virus isolates from Colorado Gregor Trebillod Dam Elizabeth Ryan

Boehringer Ingelheim International Summer Scholar (Utrecht): The complex influences of cancer chemotherapy and nutrition on the canine fecal microbiome and metabolome

Elizabeth Larsen Valerie Moorman

USDA Animal Health & Disease Scholar: Determination of short- and long-term prognoses for horses with navicular bursa abnormalities treated with navicular bursoscopy and stem cell therapy

Alidia Cornelissen Mike Lappin

Boehringer Ingelheim International Summer Scholar (Utrecht): Prevalence of bloodborne pathogens in client owned cats in the Netherland

Samuel Scheu Luciano Caixeta

USDA Animal Health & Disease Scholar: Evaluation of selective dry cow treatment on milk microbiome and post-partum udder health

Marion Cambrelin Todd O’Hara

University of Alaska Veterinary Scholar: The use of blood soaked filter papers to measure selenium and/or methyl mercury concentrations in marine mammals

Shana Wolfer Kevin Haussler

USDA Animal Health & Disease Scholar: Tissue heating and cooling properties of a dry-interface pneumatic sleeve applied to the equine distal limb

Nicole DelPino Lorrie Rea

University of Alaska Veterinary Scholar: Mercury concentrations and stable isotope values for Northern fur seals

Veterinary Scholars Summer Research Program

11

2017 VSSP ParticipantsScholar Mentor Research Project

Jackie Rivero Molly Murphy

University of Alaska Veterinary Scholar: Analysis of blood-soaked filter paper for environmental agents of zoonotic concern in rural Alaska

Nick Dannemiller Scott Carver

University of Tasmania Exchange Veterinary Scholar: Host Demographic Analysis of Feline Foamy Virus Infection in Colorado Mountain Lions