Trypanosomes

Is parasite transmitted by tsetse fly(phlebtumous)

Which causes trypanosomiasies or sleeping sickness

The parasite found in peripheral circulation but then reach the central nervous system

Stages1- trypomastigote

2_ Epimastigote

Epimastigote Trypimastigote

Life cycle

Route of infection mother-to-baby (congenital),

contaminated blood products (transfusions),

an organ transplanted from an infected donor,

laboratory accident,

contaminated food or drink (rare)

Symptoms intermittent fevers

headaches

muscle and joint aches,

malaise

Itching of the skin,

swollen lymph nodes

weight loss can occur

and Death

Diagnosis

by finding the parasite in body fluid or tissue by

microscopy

Treatment It depend on the type infection and the disease stage

Pentamidine, is the recommended drug for

first stage

other drugs (suramin, melarsoprol, eflornithine, and nifurtimox)

Presented by Sereen Hassan

Siren Ibrahim

Maha Abu lail

Thank you