Post on 02-Jan-2016
description
Trough FEV1
FF/VI 100/25mcg vs. PBOFF/VI 100/25mcg vs. FF 100mcg
FF 100mcg vs. PBO
1. Rescue-free 24hr periodsFF/VI 100/25mcg vs. PBO
FF/VI 100/25mcg vs. FF 100mcgFF 100mcg vs. PBO
Co-primary
0-24hr wmFEV1
FF/VI 100/25mcg vs. PBOFF/VI 100/25mcg vs. FF 100mcg
FF 100 vs. PBO
2. Symptom-free 24hr periodsFF/VI 100/25mcg vs. PBO
FF/VI 100/25mcg vs. FF 100mcgFF 100mcg vs. PBO
3. AQLQ+12FF/VI 100/25mcg vs. PBO
FF/VI 100/25mcg vs. FF 100mcg
If p<0.05 for co-primary endpoints move to secondary 1.
If p<0.05 for secondary 1. move to secondary 2.
If p<0.05 for secondary 2. move to secondary 3.
Sec
on
dar
y