Post on 28-Sep-2018
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XIII INTERNATIONAL WORKSHOP ON LOWER GENITAL TRACT PATHOLOGY
Course Directors
P. Davies A. Frega C. Gentili
International Scientific Committee
A. Ciavattini - Italy R. De Vincenzo - Italy J. Dillner - SwedenD. French - Italy A. Lukic - Italy B. Moscicki - U.S.K.U. Petry - Germany W. Prendiville - France
Organising Secreatariat
Adria CongrexVia Sassonia, 30 - 47922 RiminiTel. 0541 305811 c.imola@adriacongrex.it
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XIII INTERNATIONAL WORKSHOP ON LOWER GENITAL TRACT PATHOLOGY
Thursday, April 12 2018
TIME ROOM A ROOM B
08.30 – 08.50 OPENING LECTURE
08.50 – 10.20 HPV INFECTION AND CARCINOGENESIS
10.20 – 11.00 EPIDEMIOLOGY OF CERVICAL CANCER AND
HPV INFECTION
11.00 – 11.30 BREAK
11.30 – 13.00 CERVICAL SCREENING
13.00 – 13.30 LECTURE SPONSORED BY FARMITALIA
13.30 – 14.00 LECTURE SPONSORED BY BIOSTILOGIT
14.00 -14.30 LUNCH
14.30 - 15.40 CERVICAL SCREENING: THE NEW CHALLENGES
UPDATES IN MOLECULAR BIOLOGY
15.40 – 16.50 HPV POSITIVE, WHAT NEXT?
UPDATES IN CYTOPATHOLOGY
16.50 – 17.10 BREAK
17.10 – 18.00 COLPOSCOPY IN THE ERA OF HPV VACCINATION AND
HPV SCREENING ASK THE EXPERT
18.00 – 18.55 NONCOMPLIANCE WITH REFERRAL TO
COLPOSCOPY
PROGRAM AT A GLANCE
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XIII INTERNATIONAL WORKSHOP ON LOWER GENITAL TRACT PATHOLOGY
Friday, April 13 2018
TIME ROOM A ROOM B
08.30 – 10.40 VACCINATION FREE COMMUNICATIONS
10.40 – 11.10 BREAK
11.10 – 13.00 ENSURING THE SAFETY AND EFFECTIVENESS OF
COLPOSCOPY
FREE COMMUNICATIONS
13.00 – 13.30 LECTURE SPONSORED BY SHIONOGI
13.30 -14.30 LUNCH
14.30 – 15.40 PUBLIC EDUCATION AND COVERAGE RATES
PAP SMEAR: NEVER SAY NEVER AGAIN
15.20 – 17.20 THE CERVICAL CYTOPATHOLOGY IN THE
HPV TESTING ERATHE CERVICAL
CYTOPATHOLOGY IN THE HPV TESTING ERA
16.30 – 17.40 MISCELLANY
17.20 – 18.20 AWARDS AND CONCLUSIONS
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XIII INTERNATIONAL WORKSHOP ON LOWER GENITAL TRACT PATHOLOGY
FACULTY
PRO
M. Barbero - ItalyM. Benevolo - ItalyA. Biamonti- ItalyF. Boselli - ItalyE. Carico - Italy
D. Caserta - ItalyA. Castanon - U.K.
M. Cruickshank - U.K.P. Davies - Belgium
R. De Vincenzo - ItalyF. De Seta - Italy
J. Dillner - Sweden L. Dillner - Sweden
J. Doorbar - U.K.E. Giarnieri - Italy
M.R. Giovagnoli - ItalyM. Goodmam - U.S.
W. Huh - U.S.L. Mariani - Italy
B. Moscicki - U.S.P. Martin Hirsch - U.K.
G. Negri - ItalyM. O’Connor - Ireland
M. Peroni - Italy K.U. Petry - Germany
W. Prendiville - France W. Ricciardi - ItalyG. Scambia - ItalyR. Senatori- Italy
F. Sopracordevole - ItalyU. Tabuica - Moldova
F. Torcia - ItalyA. Venuti - ItalyJ. Waller - U.K.
C. Zanardi - Italy
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XIII INTERNATIONAL WORKSHOP ON LOWER GENITAL TRACT PATHOLOGY
PRO
PROGRAM
Thursday 12 / Friday 13 April 2018
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XIII INTERNATIONAL WORKSHOP ON LOWER GENITAL TRACT PATHOLOGY
Registration
Welcome P. Davies.-A. Frega - C. Gentili
ROOM A (Plenary session)
8.00
8.20
Opening Lecture Chairman: G. Scambia HPV infection and carcinogenesis: a public health perspective.W. Ricciardi
HPV infection and CarcinogenesisChairpersons: P. Davies - A. Venuti
Human papillomavirus infection and the induction of neoplasia.J. Doorbar The natural history of HPV infection in screening age women: do we have enough data to really understand what is happening in this age group?B. Moscicki Persistent vs repeated infections: can we tell the difference and does it make a difference to cervical carcinogenesis? J. Doorbar New hot topics. HPV in non HIV immunocompromised men and women: screening and manegement.B. Moscicki Discussion
Epidemiology of Cervical Cancer and HPV InfectionChairpersons: A. Castanon – A.Lukic Cervical cancer trends around the world: are we making a difference?P. DaviesHPV vaccination and its impact on HPV infection rates around the world.J. Dillner
8.30
8.50-10.20
8.50-9.10
9.10-9.30
9.30-9.50
9.50-10.10
10.10-10.20
10.20-11.00
10.20-10.40
10.40-11.00
Thursday 12 April 2018
Morning
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XIII INTERNATIONAL WORKSHOP ON LOWER GENITAL TRACT PATHOLOGY
Cervical ScreeningChairpersons: J. Dillner - C. Gentili
The current status of cervical screening programmes around the world: are we making progress where it is needed most or just improving the best?M. Goodman HPV testing for primary screening: who is doing what?A. Castanon The latest data from the HPV primary screening programmes: the benefits and the challenges that remain to be solved.M. GoodmanCervical screening: is there still a role for the Pap test?P. DaviesDiscussion
LECTURE SPONSORED BY FARMITALIA - NON ECMVulvovaginitis & HPV infection: diagnostic and therapeutic issues M. Sansone LECTURE SPONSORED BY BIOSTILOGIT - NON ECMEllacid acid/acetogenins annonaceus supplement: effects on cervical HPV related preneoplastic lesionsM. Le Donne
11.30-13.00
11.30-11.50
10.50-12.10
12.10-12.30
12.30-12.50
12.50-13.00
13.00 - 13.30
13.30 -14.00
Cervical Screening: the New ChallengesChairpersons: A. Biamonti - U. Petry
Estimating the impact of HPV primary screening and HPV vaccination on cervical cancer rates.A. Castanon The evolution of HPV testing in the U.SW. HuhHPV screening recall and follow-up recommendations: do doctors stick to the rules? M. GoodmanDiscussion
HPV Positive: what Next?Chairpersons: M. Cruickshan - M. Peroni
HPV positive: what are the triage options and their associated risksK.U. Petry
14.30-15.40
14.30-14.50
14.50-15.10
15.10-15.30
15.30-15.40
15.40-16.50
15.40-16.00
Afternoon
ROOM A
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XIII INTERNATIONAL WORKSHOP ON LOWER GENITAL TRACT PATHOLOGY
ROOM B
Updates in Molecular BiologyChairpersons: D. French - A. Venuti
Latent papillomavirus infections: the role of the HPV test. J. DoorbarGetting around in the molecular testing jungle: what clinicians and pathologists should know to properly interpret the results. L. Dillner
14.30-16.00
14.30-14.50
14.50-15.10
How does HPV status affect the treatment of low-grade cervical disease?P. Martin HirschPersistent HPV Infection without colposcopically visible cervical disease: how common and what is it the appropriate follow-up? K.U. PetryDiscussion
Colposcopy in the Era of HPV Vaccination and HPV ScreeningChairpersons: W. Huh - F. Sopracordevole
The implications of HPV vaccination for the practice of colposcopy.M. Cruickshank HPV primary screening: will this affect the accuracy of colposcopy?P. Martin Hirsch Should colposcopists be re-trained to deal with the realities of the HPV eraK.U. Petry Discussion
Noncompliance with Referral to ColposcopyChairpersons: P. Martin Hirsch - C. Zanardi
Noncompliance with colposcopy referral: the extent of the problem in different countries. U. TabuicaWhy do women decide not to go to colposcopy? M. Cruickshank,Understanding and reducing the adverse psychological impact of colposcopyJ. WallerDiscussion
16.00-16.20
16.20-16.40
16.40-16.50
17.05-18.00
17.05-17.20
17.20-17.35
17.35-17.50
17.50-18.00
18.00-18.55
18.00-18.15
18.15-18.30
18.30-18-45
18.45-18.55
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XIII INTERNATIONAL WORKSHOP ON LOWER GENITAL TRACT PATHOLOGY
Investigating diagnostic problems of CIN1 and CIN2 associated with high-risk HPV by combining the novel molecular biomarker PanHPVE4 with P16INK4a. J. DoorbarThe role of cytology and HPV genotyping in screening for anal cancer.B. MoscickiDiscussion
Updates in Cytopathology Chairpersons: M. Benevolo – E. Giarnieri
Is the new Bethesda system tailored for HPV screening and molecular diagnosis?M.R. GiovagnoliCytology triage: what molecular testing cannot provide.G. Negri Discussion
Ask the ExpertsCoordinators: P. Davies- A. Frega- C. Gentili
Open forum: what would you like to ask a panel of experts? R. De Vincenzo, J. Dillner, G. Negri, M. O’Connor, W. Prendiville
15.10-15.30
15.30-15.50
15.50-16.00
16.00-16.50
16.00-16.20
16.20-16.40
16.40-16.50
17.10-18.45
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XIII INTERNATIONAL WORKSHOP ON LOWER GENITAL TRACT PATHOLOGY
Friday 13 April 2018
Morning
ROOM A (Plenary session)
VaccinationChairpersons: M. Cruickshank - A. Lukic
HPV vaccination around the world today: the programs and the coverage rates.J. DillnerHPV vaccination: long-term efficacy and protection. What are the data?R. De Vincenzo Screening in vaccinated and unvaccinated women: are two algorithms necessary and if so how do we implement them?M. O’Connor,HPV vaccination of boys: who is doing what? J. DillnerImproving HPV vaccination coverage: what works and what doesn’t. J. WallerThe nonavalent HPV vaccine: what changes?L. MarianiDiscussion
Ensuring the Safety and Effectiveness of ColposcopyChairpersons: A.Ciavattini - M. O’Connor
Adverse sequelae after the treatment of CIN: an international comparison P. Martin Hirsch Treatment of cervical pre-cancer: current best practicW. Prendiville Colposcopy training: the similarities and differences across Europe.M. CruickshankTraining colleagues in middle income countries W. Prendiville Quality assurance of colposcopy: the European perspective K.U. PetryQuality assurance of colposcopy: the American perspective. W. HuhDiscussion
8.30-10.40
8.30-8.50
8.50-9.10
9.10-9.30
9.30-9.50
9.50-10.10
10.10-10.30
10.30-10.40
11.10-13.00
11.10-11.30
11.30-11.50
11.50-12.05
12.05-12.20
12.20-12-35
12.35-12.50
12.50-13.00
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XIII INTERNATIONAL WORKSHOP ON LOWER GENITAL TRACT PATHOLOGY
ROOM B
Free CommunicationChairpersons: A. Biamonti- R. Barbero – E.Carico
HPV INFECTION AND CANCEROGENESISCase-control study on the efficacy ofcarboxymethylbetaglucan-lactoferrin association in women with high-risk Human Papillomavirus (HPV) uterine cervical infectionA.A. Criscuolo, E. Guri, M. Ciotti, F. Sesti, E. Piccione
CERVICAL SCREENINGReducing unnecessary colposcopy by risk discrimination. HPV genotyping with NILM or low-grade cytology in screening paradigms: systematic review J. AndrewsRisk of invasive lesions in cytologically atypical glandular cells (AGC) on conventional Pap Test: follow up studyE. IsidoroPrimary cervical cancer screening with a 5-type HPV e6/e7 mRNA test: results of 10 years follow-upS.W. Sørbye , A.Rad , F.E. SkjeldestadHPV test in triage of ASC-US/LSIL - the risk of CIN3+ in 5-type HPV E6/E7 mRNA negative womenS.W. Sørbye, M.M. Slettebak, F.E. Skjeldestad Cytology and 3-type HPV e6/e7 mRNA co-testing in women 25-33 yearsS.W . Sørbye, F.E. . Skjeldestad FEDetection of CIN2+ in women with normal cytology - the added value of a 3-type HPV E6/E7 mRNA testS.W. Sørbye, B. Westre, A. Giske, H. Guttormsen, F.E. Skjeldestad Discussion
COLPOSCOPYSmartscopy: the speculoscopy applied to the smartphone can be an efficient alternative to the traditional one?C. Bondi, A. Palmeri, M. Maramai, F. CasabonaEndocervicoscopy: a new imaging technique and its accuracy in studing cervical intrapithelial lesionN. De Rosa, G. Lavitola, M.Palma, R.Gallo, M.C Pagliuca, C. Di Filippo, G. Bifulco
8.30-11.00
8.30 – 8.37
8.37 – 8.44
8.44-8.58
8.51-8.58
8.58-9.05
9.05-9.12
9.12-9.19
9.19-9.29
9.29-9.36
9.36-9.43
LECTURE SPONSORED BY SHIONOGY - NON ECMPapilocare vaginal gel innovative therapy for the treatment of LSIL P. Inghirami
13.00-13.30
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XIII INTERNATIONAL WORKSHOP ON LOWER GENITAL TRACT PATHOLOGY
How to use a low cost CCD camera for hysteroscopy and colposcopy: our “all-in-one” deviceM. Maramai, C. Bondi, A. Palmeri, F. Casabona LSIL: colposcopic pictures and indication to direct biopsy. A study of the SICPCVM.Serri, F. Sopracordevole, P.Garutti, M. Fallani, B. Gardella, P.Scirpa, M.T. Schettino, A. Del Fabro, A. Pieralli, F. Ravennati, S.Montori, R.Agrusti, M.Papiccio, A.C.Boschi, M.R. Primieri, F. Cigolot, A. CiavattiniEvidence for clinical utility of extended HPV genotyping in persistence tracking and follow-up after abnormal results and colposcopyJ. AndrewsDiscussion
MISCELLANYLymphoma of the lower female genital tractR. Sparic, A. Dobrosavljevic, J. Stulic, L. NejkovicTubulosquamos polyp in vagina together with VAIN II/IIIR. Sparić, J.Stulic, A. Dobrosavljevic, L. NejkovicDiscussion
Free CommunicationsChairpersons: D. French - E. Giarnieri - R. Senatori
EPIDEMIOLOGY OF CERVICAL CANCER AND HPV INFECTIONThe risk of cervical atypia in oral contraceptive usersI. Adhikari, T.Eriksson, T. Luostarinen, M.Lehtinen, D.ApterCountries of Eastern Europe and Central Asia: the situation of HPV infection in HIV-positive womenA.A. Popova, O.Y. Shipulina, M.O. DeulinaPrevalence of cervical HPV lesions in patients with bowel inflammatory diseases in immunosuppressive treatment and cervical screening: multidisciplinary management experience in a referral centerC.Ricci, F.Scaldaferri, F. Colombo, A. Gasbarrini, G. Scambia, R. De VincenzoRole of vaginal TIAB in cervical reepithelialisation and high-risk HPV clearance in patients with low-grade cervical lesionsC.Ricci, M.T.Evangelista, G. Scambia, R. De Vincenzo HPV-HR prevalence and type distribution in women with NILM or HSIL Pap smear in Russia.O.Y. Shipulina, M.Y. Dmitryukova, G.V.LeshkinaDiscussion
9.43-9.50
9.50-9.57
9.57-10.04
10.04-10.14
10.14-10.21
10.21-10.28
10.28-1040
11.10 – 13.30
11.10-11.17
11.17-11.24
11.24-11.31
11.31-11.38
11.38-11.45
11.45-11.55
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XIII INTERNATIONAL WORKSHOP ON LOWER GENITAL TRACT PATHOLOGY
MOLECULAR BIOLOGY AND CYTOPATHOLOGYThe risk of developing a CIN2+ lesion in women with HPV16 and 18, versus women with other HPV types: follow-up studyE. Isidoro, U. Wiesenfeld, M. Di Napoli, A. Romano, J. Dobric, C. Biagi, F. Variola, S.Tomasi, D.Santon, S.Dudine, F. Giudici, L. Di Bonito, F. Zanconati Mesenchymal stem cells from cervix: what is about age and inflammation?G. Delli Carpini, M. Orciani, M. Caffarini, R. Lazzarini, S. Guizzardi, D. Tsiroglou, R. Di Primo, A. CiavattiniMolecular study of HPV-related oropharyngeal carcinomaG. Ferrario, P. Morbini, P. Alberizzi, M. BenazzoHR-HPV negative cases of cytological HSIL and additional testing results for low and unknown risk types.G.V. Leshkina, O.Y. Shipulina, T.N. RomanyukDNA HPV testing and diagnostic cytopathology for oral cancer screening Navone R., Amodeo E., Lapucci C., Crò F., Pentenero M., Gandolfo S.Expression of E6/E7 HPV-DNA, HPV-mRNA and colposcopic features in management of CIN2/3 during pregnancyC. Leone, D. French, M. Pavone, A. Frega, D. CasertaDiscussion
TREATMENT AND FOLLOW-UP Evidence for clinical utility of extended HPV genotyping in Test of Cure after treatment of CIN2+J. AndrewsRadiofrequency and poration for the treatment of HPV genital warts: a case reportC. CatalisanoRole of “close” negative endocervical margin in treatment failure after cervical excision for cervical intraepithelial neoplasia: a retrospective studyG. Delli Carpini, A. Del Fabro, L. Alessandrini, M. Buttignol, V. Canzonieri, A. Cagnacci, F. Sopracordevole, A. CiavattiniLLETZ in woman of reproductive age diagnosed with squamous intraepithelial lesions: the problem of specimen artifactsR.Sparic, S.Kadija, R. Stefanovic, L.Jovanovic, T. Janjic, J.Bila, M. BerisavacDiscussion
11.55-12.02
12.02-12.09
12.09-12.16
12.16-12-23
12.23-12.30
12.30-12.37
12.37-12.47
12.47-12.54
12.54-13.01
13.01-13.08
13.08-13.15
13.15-13.25
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XIII INTERNATIONAL WORKSHOP ON LOWER GENITAL TRACT PATHOLOGY
ROOM A
Afternoon
Public Education and Coverage Rates Chairpersons: F.Boselli - W.Prendiville
Social and psychological impact of HPV testing in cervical screening. J. WallerReaching under- or never-screened women: is self-sampling the answer? L. Dillner,The impact of HPV vaccination on cervical cancer screening coverage: are the predictions proving to be true? M. CruickshankHPV vaccination for adolescents, Pap screening for under-30’s, HPV screening for over 30’s: how can we effectively communicate all this to ensure high programme participation? M. O’ConnorDiscussion
HPV and Vaginal InfectionChairpersons: A. Biamonti - U. Tabuica
The role of vaginal microbiome in HPV infection and disease. B. Moscicki Chlamydia trachomatis infection: epidemiology, treatment and its role in HPV disease F. De Seta,The effect of intrauterine devices on acquisition and clearance of human papillomavirusB. Moscicki Discussion
MiscellanyChairpersons: R. Senatori- F. De Seta
HPV and fertility. D. CasertaPotential innovations in cervical precancer management W. Prendiville,The role of oral contraception and hormone replacement therapy in HPV infection and disease. F. Torcia The ultrasound in the evaluation of preneoplastic and neoplastic lesions of the uterine cervix U. TabuicaDiscussion
14.30-15.40
14.30-14.45
14.45-15.00
15.00-15.15
15.15-15.30
15.30-15.40
15.40-16.30
15.40-15.55
15.55-16.05
16.05-16.20
16.20-16.30
16.30-17.40
16.30-16.45
16.45-17.00
17.00-17.15
17.15-17.30
17.30-17.40
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XIII INTERNATIONAL WORKSHOP ON LOWER GENITAL TRACT PATHOLOGY
The Cervical Cytopathology in the HPV Testing EraCoordinators: M.R. Giovagnoli - G. NegriAn interactive seminar slide of cervical cytopathology.
15.20-17.40
ROOM A (Plenary session)
Presentation of the Best 3 Free Communications and Award for the BestChairpersons: P. Davies - A. Frega - C. Gentili
General Discussion
ECM Test
Prize Giving for the Three Best Speakers and Conclusions
17.40-18.00
18.00-18.10
18.10-18.20
18.20-18.30
ROOM B
Pap Smear: Never Say Never AgainChairpersons: M. Benevolo – E. Carico
Don’t forget me: cytology of HPV negative lesions. G. NegriWhat clinicians need from cytology. W. HuhDiscusison
14.30-15.20
14.30-14.50
14.50-15.10
15.10-15.20
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XIII INTERNATIONAL WORKSHOP ON LOWER GENITAL TRACT PATHOLOGY
1. Cic Editore2. Becton Dickinsons Italia 3. Farmitalia 4. Digi Medica Snc5. Fujirebio Europe6. IDI Pharma7. Bio Stilogit Pharmaceuticals 8. S&R Farmaceutici 9. smart10. Morgan 11. Synlab Italia
12. Centrel 13. Difass International 14. Arrow Diagnostics 15. EuTylia16. Sakura Italia 17. Roche Diagnostics18. Depofarma 19. Hologic Italia 20. Farma-Derma21. Verduci Editore
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XIII INTERNATIONAL WORKSHOP ON LOWER GENITAL TRACT PATHOLOGY
EXHIBITION AREANH Hotel Villa Carpegna | ROMA
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XIII INTERNATIONAL WORKSHOP ON LOWER GENITAL TRACT PATHOLOGY
GENERAL INFORMATION
CONGRESS VENUENH Hotel Villa CarpegnaVia Pio IV, 6 | 00165 ROMA (RM) | Tel +39 06 393731www.nh-hotels.it/hotel/nh-roma-villa-carpegna
LANGUAGE English will be the ufficial language of the Workshop. Simultaneous translation into Italian will be provided.
ITALIAN ECM ACCREDITATION The meeting will be accredited for the ECM credits for Italian doctors.To obtain credits it is necessary to attend the meeting. No promotional activities will be permitted in the same room before, during, or after an ECM activity.The specialities and disciplines able to apply for Italian ECM credits are:
Medico Chirurgo: Anatomia Patologica; Igiene, Epidemiologia e Sanità Pubblica; Ginecologia e Ostetricia; Oncologia; Patologia Clini-ca (laboratorio di analisi chimico-cliniche e microbiologia)Biologo: Anatomia Patologica; Igiene, Epidemiologia e Sanità Pubblica; Patologia Clinica (laboratorio di analisi chimico-cliniche e microbiologia)Tecnico di laboratorio biomedicoInfermiere ed ostetrica