Post on 26-Mar-2015
The POWER of Cranberry seed extract
together with the super-antioxidant
AstaXanthin
Benefits of Taking AstaCran®
Advantages of AstaCran® AstaCran® has extremely good stability
NO harmful solvent residues
Flaxseed and fish oils have a very short shelf life
These oils actually become rancid in short time and can (in some cases) become carcinogenic
No other supplement provides such a balanced ratio of essential fatty acids
AstaCran ® is derived from highly-renewable and safe sources
Advantages of AstaCran®1. Source of balanced EFA’s2. Super Antioxidant3. Aids in maintaining cardiovascular health4. Aids with cholesterol management5. Protects skin and eyes from photic injury6. Reduce risk factors associated with macular
degeneration7. “Anti-Aging” properties via reduction of oxidative
stress8. Balanced EFA’s and super antioxidant in a single
dose (Savings $$)
AstaCran®
Cranberol™
Cranberry seed extract
Zanthin™
Astaxanthin complex
Cranberol™
Cranberry seed extract
Cranberry seeds
Supercritical CO2 extraction method
• NO harmful solvent residues
High amounts of Essential Fatty Acids (EFA’s)
Omega-3 and Omega-6
Also possesses antioxidants
High levels of Phytosterols
Cranberries Vaccinium
macrocarpon
Cranberry Seed Extract
Super Critical CO2 extraction
Extraction performed under high
pressure using CO2 as a solvent
When extraction is complete, CO2 gas leaves NO residue (This may not be true with other commonly used solvents)
• This is an exception, not the standard
Highly sustainable source of a balanced ratio of Essential Fatty Acids (EFAs)
Essential Fatty Acids
Polyunsaturated Fatty Acids(PUFAs) “double bond”
Omega-3 and Omega-6
Essential because your body doesnot produce them. Acquired from diet or food supplements
Nutritionists have found that a balanced Omega-6/Omega-3 ratio of 1:1 is best for optimal health
EFA’s – Omega-6 & Omega-3 The current western diet:
15:1 and higher ratio
Recommended dietary ratio: Between 5:1 and 10:1 1:1 ratio in humans is
ideal
The best supplemental source should have as close to a 1:1 ratio as possible
Omega-6
Linoleic acid (LA) Most commonly produced Essential
Fatty Acid in agricultural seed oil production Majority intake from vegetable oils
Highly unbalanced amounts of LA are bad because they promote inflammation, which can lead to many health problems
Primarily beneficial when in balance with Omega-3’s Alpha-Linoleic Acids (ALAs)
This converts in the body to gamma-Linolenic acid (GLA) and then to prostaglandins that help regulate inflammation and blood pressure, as well as heart functioning.
Omega-3
ά Linolenic acid (ALA)
High concentrations of Omega-3 improves vitality of the skin
Absorption is enhanced when combined with Omega-6
As our diets have changed, Omega-3 consumption has decreased to a ratio that is associated with degenerative conditions
Omega-3 helps reduce LDL cholesterol
Other Sources Other EFA sources
Fish and shellfish
Flaxseed (linseed)
Canola oil, hemp oil, soya oil
Chia seeds, pumpkin seeds, sunflower seeds
Leafy vegetables and walnuts
AstaCran can replace ALL other supplemental EFA sources (BIG savings)
Cranberol™ Antioxidants
Tocopherols
Vitamin E family
Powerful antioxidant
Tocotrienols
Also a form of Vitamin E
40-60x stronger than tocopherols as an antioxidant
What is an Antioxidant? An·ti·ox·i·dant
A substance (as beta-carotene or vitamin C) that inhibits oxidation or reactions promoted by oxygen, peroxides, or free radicals.
Merriam-Webster Online
It gives, takes, or traps an electron.
Phytosterols play an important role in maintaining a healthy cholesterol level
Reduces cholesterol absorption in the intestines
Similar chemical structures that compete with cholesterol for absorption.
Significant for cardiovascular health
Beta-sitosterol
Helps reduce blood levels of cholesterol Stigmasterol
Phytosterols
Cholesterol
Low Density Lipoproteins (LDL)
So called “Bad” cholesterol.
Transports cholesterol into the arteries.
High Density Lipoproteins (HDL)
So called “Good” cholesterol
Suspected to carry cholesterol from within* arteries to liver for redistribution or expulsion
*ath·er·o·ma - 1: Fatty degeneration of the inner coat of the arteries 2: An abnormal fatty deposit in an artery
Merriam-Webster Online
Cranberol™
Cranberol can aid and supporta healthy cardiovascular system
Aid in maintaining healthy cholesterol levels
Aid in reduction of oxidative stress
Desirable source for a balanced ratio of EFA’s
Doesn’t turn rancid like many other sources of EFA’s
Zanthin®
Astaxanthin complex Super-antioxidant
Prevents oxidative damage 418g Atlantic Salmon = 3mg of astaxanthin.
(1 pound = 453.59237 grams)
Fish is becoming less desirable as a source for necessary compounds due to a concern over the rising levels of mercury, and various other heavy metals.
Source of Zanthin® Haematococcus microalgae
Haematococcus pluvialis – Unicellular green algae– Found in Freshwater bodies
Distribution of Astaxanthin stereo isomers in selected organisms (Bjerkeng1997)
SPECIES (3S,3’S) (3R,3’R) & (3R,3’S)
(3R,3’R)
Yeast (Phaffia sp.) --- <2% >98%
Micro algae (Haematococcus)
100% --- ---
Synthetic Astaxanthin (Carophyll Pink La Roche)
25% 50% 25%
Atlantic Salmon 78-85% 2-6% 12-17%(Schiedt et al 1981)cited in Foss 1984
Haematococcus Pluvialis
Potent source of astaxanthin Highly renewable Safe Grown in a controlled environment
Other Sources Abundant in Nature (in water) Found in Salmon, Trout, Crustaceans, Crawfish,Pacific Cod, Scallops, Mackerel,
Flounder, and other commercial seafood
Renewable
Species Content (mg/kg)
Sockeye Salmon 26-37Atlantic Salmon 3-11Krill 46-130
Astaxanthin Concentration
Species Amount of
Astaxanthin present per Kilogram
Atlantic Salmon 3 - 11mg
Sockeye Salmon 26 - 37mg
Rainbow Trout 1 - 13mg
Yeast (Phaffia sp.) 30 - 800mg
Algae (Haematococcus pluvialis)
10,000 - 30,000mg
Zanthin® Astaxanthin
Super-antioxidant
Properties of Astaxanthin Decreased DNA damage. Arrests mitochondrial free radicals
Powerful Antioxidant Crosses blood-retina barrier
Immune-modulatory activity Provides anti-inflammatory activity
Increases strength and endurance
Protects eyes and skin from photic injury
Antioxidant Studies
Anti Oxidant Studies
Naguib, Y., "Antioxidant Activities of Astaxanthin and Related Carotenoids,"Journal of Agricultural and Chemistry, v.48 (4), pp. 1150-1154.
ORAC Values of Antioxidants
0
0.2
0.4
0.6
0.8
1
1.2
1.4
1.6
astaZanthin™Standardized
Extract
NaturalLycopene
SyntheticAstaxanthin
Natural alpha-tocopherol
Natural a-bCarotene mix
NaturalTocotrenols
Natural Lutein Natural beta-Carotene
OR
AC
Va
lue
pe
r u
nit
ac
tiv
e
ORAC – Oxygen Radical Absorbance Capacity
AstaZanthin™ Standardized ExtractNatural LycopeneSynthetic AstaxanthinNatural alpha-tocopherolNatural a-b Carotene mixNatural TocotrienolsNatural LuteinNatural Beta Carotene
1.3800.5960.4190.3810.3450.3180.2800.242
Astaxanthin
Astaxanthin was 10 - 50 times stronger than vitamin E in the lipid peroxidation of mitochondria membranes using the TBA method Inoue (1990)
Astaxanthin is 10 times stronger than zeaxanthin, lutein, beta-carotene and canthaxanthin
Astaxanthin is 100 times greater than alpha-tocopherol against active oxygen species in the thiobarbituric assay
Miki (1991)
Strength and Endurance Fitness (submaximum load – Astrand method)
Strength/Explosivity (Wingate method of maximum effort)
Endurance (knee-bending technique) Malmsted, C.L. Gustavsberg,
Sweden
“Dietary Supplement with Astaxanthin-Rich Algal Meal Improves Muscle Endurance - A Double-blind Study on Male Students” N=40
6 Month Treatment Pre-treatment
standardized exercise tests/endurance
(p<0.05)
Significant Improvement in strength/endurance
(p<0.05)
Strength and Endurance
Increased Carotenoid content