The lipid language of plant-fungal interactions

Mr. GAURAV KUMAR PANDITSCHOOL OF LIFE SCIENCE

UNIVERSITY OF HYDERABAD

gauravbiologist@uohyd.ac.in

The lipid language of plant-fungal interactions

To understand the cross-kingdom communication between organism

Do plants and fungi communicate via oxylipin language? How fungi and plants recognize exogenous oxylipins ? What is the significance of this discussion ?

OBJECTIVE

Introduction Lipids play vital roles in numerous physiological processes in

living organisms.

oxygenated polyunsaturated fatty acids (PUFA): oxylipins.

Mammals oxylipins : eicosanoids

Microbial oxylipins : fungal oxylipins are better understood .

Oxylipins such as jasmonates are able to regulate signal cross-talk with other hormones.

Similarity in biosynthesis and Structure of Fungal & Plant Oxylipins

Enzymatic & Non-Enzymatic Biosynthesis of Oxylipin in plant

How fungi induce plant lipid metabolism to utilize plant oxylipins ?

Model for the use of host ligand mimicry ( coronatine ) to manipulate plant defense response that benefit the fungus.

Hypothetical model of oxylipin-mediated signal communication between plants and fungi

G-Protein mediated regulation - GPCRs

What is the significance of this discussion ?T know about – Seed contamination by mycotoxigenic fungi mycotoxins such as aflatoxin causing significant economic losses and food

safety concerns. Aflatoxin is among the most carcinogenic compound naturally found and

when ingested it has acute toxic, immunosuppressive, mutagenic, teratogenic and carcinogenic effects, mainly on the liver.

Future Aspect – Molecular signaling during plant-pathogen interactions must be understood

to create and apply better forms of disease resistance in staple crops. Notes

Lipoxygenase or LOX, in plants, initiates biosynthesis of most oxylipins some of which are shown to regulate growth and development, biotic and abiotic stress defense, sex determination, programmed cell death, and senescence.

Fungi have another family of dioxygenases , psi-producing oxygenase (PPO) that incorporate molecular oxygen into fatty acids to produce Psi (precocious sexual inducer) factors; they stimulate asexual or sexual spore development.

School of Life SciencesUniversity of Hyderabad

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