T-Cell Receptor Signaling

ATF2 NF-B

NFATElk1SRF

MKK4/7

MKK3/6

Ca2+Ca2+

IBDegradation

MEK1/2

ERK1/2

ITKFyb

CARD11

BCL10PAK

MAP3Ks

CalnCaln

NF-BIB

Cell Proliferationand DifferentiationCell Proliferation

and Differentiation

Antigen-Presenting CellAntigen-Presenting Cell

Active Release andTranslocation of

CTLA4 to Membrane

Active Release andTranslocation of

CTLA4 to Membrane

CytoskeletalRemodellingCytoskeletalRemodelling

EndosomeEndosome

ImmuneResponseImmune

Response

IL-2 GeneExpressionIL-2 Gene

Expression

CTLA4CTLA4

TCR-CD3

ComplexTCR-CD3

Complex

MHC-II

2009ProteinLounge.com 2009ProteinLounge.comC

T-Cell Receptor Signaling

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Transcript of T-Cell Receptor Signaling

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Word bank -signaling molecule -cell receptor -signal transduction pathway -nuclear signaling -cascade -phosphorylation -ATP -protein -response -nucleus.

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BAM1/2 receptor kinase signaling drives CLEBAM1/2 receptor kinase signaling drives CLE peptide-mediated formative cell divisions in Arabidopsis roots Ashley D. Crook a,1, Andrew C.

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