Post on 05-Jan-2016
Stages of mitosisStages of mitosis•The stages are prophase, metaphase, anaphase and telophase.
Abnormalities of mitosisAbnormalities of mitosis
• 1- Non dis-junction of chromosomes.
• 2- Un usual mitotic figures by rapidly proliferation cells of malignant tumours.
Stages of meiosisStages of meiosis• 1- First meiotic division include
Prophase I ,Metaphase I, Anaphase I and Telophase I
• Prophase I include Leptotene, Zygotene, Pachytene, Diplotene and Diakinesis.
• 2- Second meiotic division include Prophase II, Metaphase II, Anaphase II and Telophase II.
Factors affecting in cell divisionFactors affecting in cell division•1 -Radiation ( X-ray).
•A) – Arrest of mitosis Lethal dose ( High dose).
•B) – Mutation ( mutagenic effect) not lethal dose ( Low dose).
•2 -Drugs include Colchicine , Vincristine, Vinblastine are anti-mitotic drugs which inhibit the formation of microtubules and arrest of mitosis in metaphase.
•Their effect is reversible