Self Organizing Genomes with Real Time Consent

DNA Guide, Inc. All rights reserved 2012

Alice Rathjen, President, Founder

alice@dnaguide.com

Genome

Digital Human Being

The Evolution of Digital

HumanityElectronic

Health Records

Next Generation

Sequencing

Technologies

Molecular

DiagnosticsSocial Networks

20121992

Pattern:

People upload/create data and

control who they share it with.

The power of

Self- Organizing

Genomes

Imagine….

The advantages of

Real Time

Consent

Electronic

Health Records

Next Generation

Sequencing

Technologies

Molecular

DiagnosticsSocial Networks

20222012Research

Governments/Passports

Electronic Health Records

Patient Groups

Ancestry

Gaming (DNA Avatars)

Biometric Access/ E-Commerce

Online Identity Services

Citizen Science

Non-Govt Health Organizations

Disaster Response / Epidemics

2 Billion Genomes in

10 Years?

The Industries Problem... No Path to Market

Genetic Data Explosion

Huge investment in

Sequencing

Technologies and

Molecular Diagnostics

Personalized Medicine

R&D

Pharma /

Clinical

Trials

Consumers/

PatientsIN

SU

RA

NC

E

Regulation, Privacy, Ease of Use

Health

Services

Will we see a Facebook for DNA or Biological DNS - where people

choose an entity to register and host their genome?

Regulation

www.DNAguide.com

Problem of Fear and Ignorance

T

A T

G C

T

A

C

G

A

The Patient Has Changed

Doctor, it hurts

when I do this

Doc, I was born

this way

New Path to Market?

Consumer/

Patient Controls

Access To Their

DNA via Real

Time Consent

Those

Providing

Valuable

Information

and Services

Get Rewarded

T

G

C

A

Genome Browsers &Non-Scientific Users

(Mitochondria)

Solution is to Manage Interpretation and Access Down to the Base Pair Level

Technology can Enable Dynamic Regulation & Compliance

Quality of Science

Medical Utility

Viewing Risk

(Graded) A,B,C,D,F

W = Withdrawn

I = Incomplete(by Scientific Community)

(by Health Care Providers/ Payers)

E =

Everyone,

PG = Physician

Guidance R =

Restricted

(Genetic Counselors, Ethics)

Information Category Rating

(Five Star Rating)

(Movie Rating)

Building the Scaffolding for Future Personal Biological Data

Patient as Owner

Security Token

Map of Your

Genome

Map of Your

Body

DNA sample used to create

patient centered universal

health record based on real

time consent. (Patient

submits DNA sample to prove

ownership , receives login to

setup user accounts).

“Google Maps” for your genome

with the ability to manage

interpretation and access down to

the DNA base pair level. Convert

$1,000 genome into 2 minute

genome at the point of care.

Medical records, images and

gene expression data to be

linked to a map of the your

human body and to genomic

location.

Grand Slam of Electronic Health Records

Navigating Genetic Data

Privacy, Regulation and Ease of Use

Method for preparing and using personal and genetic profiles

DNA Guide, Inc. All rights reserved 2012

Alice Rathjen, President, Founder

alice@dnaguide.com