Poorindoorairquality.

• Indoor-generatedairpollutants• Outdoorairpollutionindoors

• GrowingupinNewZealandstudy

TinTinEnvironmentalHealth2016

• Penicillium,Aspergillus,andCladosporiumposearespiratoryhealthriskinsusceptiblepopulations

• increasedexacerbationofcurrentasthmasymptomsassociatedwithincreasedlevelsofPenicillium,Aspergillus,Cladosporium,andAlternaria species

JACI2015

2010

Perfluoroalkyl acids(PFFAs)

• children’sbedroomairinNorthernEurope• waterandstainrepellencyintextiles,papersandboards

Winkins EnvironmentalPollution2017

• MVOCshavebeenproposedassentinelmarkersofmicrobialinfestationonhiddenbuildingsurfaces

• growingbodyofevidencesuggestthattheyareproducedbynotonlybymicrobes,butalsobysyntheticbuildingmaterials

2016

• awidearrayofchemicalsusedineverydayproductsfindtheirwayintoindoorenvironments

• vulnerablesubpopulationslikechildren,arecontinuouslyexposed

• indoorenvironmentisahavenforchemicalsassociatedwithreproductiveanddevelopmentaltoxicity,endocrinedisruption,cancerandotherhealtheffects

questions

• excludeETS,includepassivevaping?• divideexposuresinto– indoorgenerated• clearevidence(meta-analysisetc.)vs.“ofconcern”

– outdoorgenerated• mitigatingeffectsbydesign