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Place Title Here. Resident Name Mentor Name. Thoughts. - PowerPoint PPT Presentation

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Place Title Here

Resident Name

Mentor Name

Thoughts

• Remember for your project proposal, you will probably not have results and discussion. However, you can let them know where you are at in the process and ask for their guidance and input. This is your opportunity to educate the faculty and your fellow residents as to how you plan to accomplish the project. Plus, you are drawing on the experience of others who have already been there and done that. By involving others early in the process, you will be able to manage the project. If not, the project will manage you.

• If all else fails, ask for help!

More Thoughts

• As in life, there is a process/steps that we go through. Birth, childhood, teenager, adult, elder, death (you get the idea). Currently, in this process, you are an OBGYN resident who has the opportunity to do research. Though research maybe relatively new to you, it has been present since the beginning of time. Therefore cherish the fact that those before you have already constructed a pathway for you to follow. It is call the scientific method. These steps follow:

Stating the questions Literature search

ObjectiveDesign

Materials and MethodResults Discussion

Conclusion

After you give your project proposal, you should be through the first, five steps. In other words, your are over halfway to completion.

Rule of Thumb

• Don’t put any information on a slide that will not fit reasonably on a 3 X 5 index card.

Introduction(or Background)

• Heading – Included sub-headingsIncluded sub-headings11

1) Author, Year (references)

Cyr61 Structure

• 379 amino acids• 42 kDa• Cysteine rich • Encoded on chromosome 1

Example

CCN1 0 AAAAIGFBPIGFBP VWCVWC TSP1TSP1 CTCT

IGFBP: Insulin-like growth factor binding protein motifVWC: von Willibrand Type C moduleTSP1: thrombospondin type I repeatCT: C--terminal module

Objectives

• To…

Materials and Methods• Design

– Retrospective, Prospective, Cohort, Observational, Double blind, randomized trial, survey

• Patient Demographics – Age– Ethnicity– G’s and P’s.

• Methods– Describe methods (use project protocol template)– Inclusion/exclusion criteria– Statistical Analysis (Power Analysis)

Study Design

PT POSTED FOR ABDOMINAL OR VAGINAL HYSTERECTOMY

NOT ELIGIBLE ELIGIBLE

CEFAZOLIN + PLACEBO CEFAZOLIN + METRONIDAZOLE

Cultures, Surgery Cultures, Surgery

Postoperative Follow-up Postoperative Follow-up

Example

Results

Example

• Western blot analysis of ECC1 for Cyr61

– Treated with diethylstilbestrol (DES)

– Treated with epidermal growth factor (EGF)

Regulation in Endometrium

Results

Endometrial Adenocarcinoma

Normal endometrium

Mid

-sec

reto

ryPr

olife

rativ

e

Endometrial adenocarcinoma

Cyr61 Immunostaining• Expression increased in endometrial cancer compared with normal mid-secretory endometrium

Example

Results

Example

Endometrial Adenocarcinoma

• RT-PCR for Cyr61 in normal cycling endometrium and in endometrial adenocarcinoma

(* P<0.001)

Results

Group BV Status Postop

InfectionNo Postop Infection

P

MetronidazolePositive

Intermediate

Negative

3 (17.6%)

3 (27.3%)

3 (12.5%)

14 (82.4%)

8 (72.7%)

21 (87.5%)

0.6

Placebo

Positive

Intermediate

Negative

2 (16.7%)

2 (11.1%)

6 (25.0%)

10 (83.3%)

16 (88.9%)

18 (75.0%)

0.5

Table 1. Preoperative BV Status versus Postoperative Infection Rate versus Metronidazole/Placebo

Example

Discussion

• Start discussion here

Conclusions

• Start conclusions here

Future Studies

• Start future studies here

Acknowledgments

• Add acknowledgments here