PRESENTATION ON

PIROCIN 2% OINTMENT

Prepared by:

Biplob Kumar Sarker,

Product Executive,

Product Management Department

DISEASE PART

Skin Infection: Skin infection is an infection of the

skin.

1. Bacterial Skin Infection

2. Fungal Skin Ifcection

BACTERIAL SKIN INFECTION

Bacterial skin infections include: Impetigo: Impetigo is a highly contagious bacterial skin

infection most common among pre-school children.

It is primarily caused by Staphylococcus aureus, and sometimes by Streptococcus pyogenes.

Erysipelas: Erysipelas is an acute streptococcus

bacterial infection of the deep epidermis with lymphatic spread.

Cellulitis: Cellulitis is a diffuse inflammation of

connective tissue with severe inflammation of dermal and subcutaneous layers of the skin.

IMPETIGO Overview: Impetigo is a common skin infection caused

by streptococcus (strep) or staphylococcus (staph) bacteria.  

If you have a cut, bite (insect, human or animal) graze, eczema or injury to the skin, this usually heals but sometimes bacteria can enter the body and grow there, causing inflammation and infection.

WHO GETS IMPETIGO?

It is most common in children, infants and people who have lower immune function for some reason.

Impetigo is very easily spread to other parts of your body or other people.

Also more common if children or adults are living in poor or crowded houses

 

CONTI…

Impetigo is contagious, meaning it is easy to spread it to other parts of your body or to other people such as family members or classmates

If the fluid that oozes from impetigo blisters touches an open area on your skin, you may get impetigo too.

SYMPTOMS

Impetigo often starts as a single blister or red lesion

Blisters may fill with pus or yellow honey coloured fluid

  Also starts as any lesion that doesn't heal

and develops a crusty scab

Common sites are skin lesions on the face, lips, arms, or legs, that spread to other areas

TREATMENT OPTION

Remove crusted area by washing with saline or antibacterial soap (1 to 3 times each day).

Apply topical antibiotic or antiseptic ointment if prescribed.

Medicon introduces Pirocin

2% Ointment

PRODUCT PROFILE Brand Name : Pirocin

Generic Name : Mupirocin

Therapeutic Group :Antibacterial

Official specification : BP

Dosage Form : 2% Ointment

Strength : 20 mg

Pack Size : 10 gm tube

INDICATION

PIROCIN ointment is indicated for the topical treatment of impetigo due to:

Staphylococcus aureus and Streptococcus pyogenes

MECHANISM OF ACTION Mupirocin reversibly binds to bacterial

isoleucyl-tRNA synthetase, an enzyme which promotes the conversion of isoleucine and tRNA to isoleucyl-tRNA.

Prevention of this enzymes from functioning properly results in the inhibition of bacterial prote in and RNA synthesis.

DOSAGE AND ADMINISTRATION

A small amount of Pirocin 2% ointment should be applied to the affected area three times daily for upto 10 days.

The area treated may be covered with gauze dres sing if desired.

TARGET DOCTORS

-Skin and VD Specialist

-Medicine Specialist

- Potential GPs

-RMP/PC

MAJOR COMPETITORS

Brand Name Company

Bactron Oint. BiopharmaBactoderm Oint. UniDermaBactroban Oint. GlaxoSmithKlineBactrocin Oint. SquareDermoban Oint. OpsoninMupi Oint. AlcoMupibac Oint. PharmasiaMupiderm Oint. HealthcareMupiron Oint. SK+FMuroderm Oint. GeneralMuron Oint. Drug Int.Trego Oint. Incepta

SPECIAL BENEFITS OF PIROCIN

Offers treatment superiority over oral antibiotic therapy in Impetigo.

Ensures better clinical response and pathogen eradication rate.

Effective and safe in the treatment of primary and secondary skin infection.

Offers treatment superiority over oral Flucloxacillin and Erythromycin.

CONT………..

Low incidence of adverse effects and cross-resistance.

Shows excellent activity against gram-positive staphylococci and streptococci.

Fewer adverse effects than systemic antibiotics.

Easier to administration. Short term treatment option.