Post on 31-Oct-2021
PhoxillumRenal Replacement Solution 1.0 mmol/L phosphate
PhoxillumRENAL REPLACEMENT SOLUTION
The only FDA approved CRRT replacement solution that contains phosphate in a 5L bag
References: * Luca, Bigatello M. et al. Critical Care Handbook of the Massachusetts General Hospital, 4th Edition, 2006
Available in Two Formulations For Individualized Patient Therapy
Indication PHOXILLUM solution is indicated in pediatric and adult patients for use as a replacement solution in Continuous Renal Replacement Therapy (CRRT) to replace plasma volume removed by ultrafiltration and to correct electrolyte and acid-base imbalances. It may also be used in case of drug poisoning when CRRT is used to remove dialyzable substances.
Important Risk InformationPHOXILLUM solution can affect electrolytes and volume and may result in hyperkalemia or hyperphosphatemia. Monitor hemodynamic status and fluid inputs and outputs, potassium, phosphorous, calcium, other electrolytes and acid-base balance throughout the procedure. Abnormalities may be corrected by changing the formulation of replacement solution and/or dialysate, supplementation, or adjusting flow rates appropriately. PHOXILLUM replacement solutions contain hydrogen phosphate, a weak acid that may increase the risk of metabolic acidosis. PHOXILLUM solution can effect blood glucose levels resulting in hypo- or hyper-glycemia depending upon the dextrose content of the replacement solution. Monitor blood glucose levels regularly. Patients may require initiation of or modification of antidiabetic therapy or other corrective measures during treatment.
For more information, please see the enclosed full Prescribing Information.
PHOXILLUM Solution is available in two formulas varying in calcium and bicarbonate.
Calcium Formula Calcium-Free Formula
Plasma* PHOXILLUM BK 4/2.5 PHOXILLUM B22K 4/0
Potassium K+ (mEq/L) 3.5–5.0 4.0 4.0
Calcium Ca2+ (mEq/L) 2.3–2.6† 2.5 0
Magnesium Mg2+ (mEq/L) 1.4–2.0 1.5 1.5
Sodium Na+ (mEq/L) 135–145 140 140
Chloride Cl- (mEq/L) 100–108 114.5 122.0
Phosphate HPO42– (mmol/L) 0.8-1.5 1.0 1.0
Bicarbonate HCO3- (mEq/L) 22–26 32 22
Lactate (mEq/L) 0.5–2.2 0 0
Dextrose (mg/dL) 70–110 0 0
Osmolarity (mOsm/L) 280–296 294 290
NDC Number 24571-116-05 24571-117-05
Catalog Number 114905 114906
†Ionized Calcium
Baxter, Gambro and Phoxillum are trademarks of Baxter International Inc., or its subsidiaries.
USMP/MG144/15-0005(4) 09/19
Baxter Healthcare CorporationOne Baxter ParkwayDeerfield, IL 60015
www.baxter.com
For Customer Support call 800-525-2623