Post on 31-May-2015
PATHOLOGY DEPARTMENT
FACULTY OF MEDICINE
AL-AZHAR UNIVERSITY
Allergic Nasal Polyp
1
2
3
4
1) Resp. epith. 2) Edematous core 3) Hyperplastic mucous
glands 4) Mucus
Allergic Nasal Polyp
1
2
3 4
1) Hyperplastic resp. epithel. 2) Edematous stroma 3) Dilated congested capillaries 4) Eosinophils
1- Fibrinous (inflammation) Pleurisy
4- Lobar Pneumonia, red hepatization (Diagram)
Alveolar
capillary
Alveolar
wall
Alveolar
lumen
Alveolar
Lumen
Alveolar
wall Alveolar
Capillary
4- Lobar Pneumonia, red hepatization
(Low Power)
Alveolar
wall
Alveolar
Lumen
14- Chronic Venous Congestion, Lung (Diagram)
Congested Alveolar
capillaries
Heart Failure Cell
Red Cells
14- Chronic Venous Congestion, Lung
Low Power
Alveolar Wall
Alveolar Capillary
Alveolar Space
14- Chronic Venous Congestion, Lung
High Power
Heart Failure
cells
Thick Congested Alveolar wall
Brown Hemosiderin
Lobar Pneumonia, Grey Hepatization 1
2
3
4
1) Inflammatory cells 2) Clumps of fibrin and edema 3) Fragmented RBCs 4) Congested alveolar capillaries
Bronchopneumonia
Bronchopneumonia
Emphysema
1
2
3
1) Distended, distorted, thin-walled, and wide alveolar spaces 2) Intralveolar spur 3) Thick walled capillaries
Emphysema
1
2
3
1) Distended, distorted, thin-walled, and wide alveolar spaces 2) Thick walled capillaries 3) Inflamed alveolar speta with congested blood vessel
Infarction, Lung
Infarct
Congested lung tissue
Oat Cell Carcinoma
1
2
1) Lung tissue 2) Tumor showing peripheral infiltration of lung tissue (short arrows)
Oat Cell Carcinoma
Malignant cells
Acute Diffuse Glomerulonephritis
1) This glomerulus is enlarged, hypercellular and capillary loops are poorly defined. 2) Increased numbers of epithelial, endothelial, and mesangial cells as well as neutrophils in and around the glomerular capillary loops. 3) Tubule shows intraluminal casts
1
2
3
Rapidly Progressive Glomerulonephritis
1) Epithelial creascent 2) Compressed and distorted glomerular capillaries 3) Edematous stroma
1
2
3
Chronic Glomerulonephritis
1
2
3
4
1) Global glomerulosclerosis 2) Tubular thyroidization 3) Arteriolosclerosis 4) Interstitial chronic inflammatory cells
Infarction, Kidney High Power
Viable
Tissue
Inflammatory
Zone Infarct
Infarction, Kidney
High Power
Renal Cell Carcinoma
1
2
1) Sheets and cords of vacuolated malignant tumor cells 2) Thin vascularized connective tissue septa
Nephroblastoma
1
2
3
1) Blastema cells 2) Epithelial cells 3) Undifferentiated stroma cells
30- Bilharziasis, urinary bladder Diagram
Transitional epithelium
Calcified Ova Brun’s nest
Fresh Ova
Cystitis Cystica
Brun’s nest
Transitional
Epithelium
30- Bilhaarziasis . Urinary Bladder Epithelial Changes
Epithelial Hyperplasia
Cystitis
Glandularis
Epithelial
Hyperplasia
30- Bilhaarziasis . Urinary Bladder
Epithelial Changes
Prostatic Hyperplasia
2
1
1) Hyperplastic prostatic acini 2) Fibromuscular stroma
Prostatic Hyperplasia
1
2
1) Dilated acinus containing corpora amyllacae 2) Papillary formation
Seminoma
1
2
1) Benign-looking testicular tissue 2) Tumor tissue
Seminoma
1
2
1) Cords of seminoma cells 2) Vascularized fibrous septa
2- Acute Suppurative Appendicitis (Diagram)
2- Acute Suppurative Appendicitis
(Low Power)
2- Acute Suppurative Appendicitis
(Low power)
2- Acute Suppurative Appendicitis (Congested dilated Bl. Vs. with PNLs infiltration)
Amoebic Colitis
1
2
3
1) Flask-shaped ulcer 2) Undermined edge 3) Necrotic floor
Amoebic Colitis
1
2
1) Entamoeba histolytica 2) Inflammatory cells
29- Bilharzial Polyp, colon Diagram
Bilharzial
Ova
Vasular C. T. Core
Polyp
30- Bilharzial Polyp, colon Low Power
Colonic
mucosa
Calcjfied Bilharzial Ova
In C.T.Stroma Calcified Bilharzial Ova in C.T. Stroma
42- Adenoma, Intestine
56- Adenocarcinoma, Colon
adenocarcinoma
57- Mucoid Carcinoma, Colon
12- Fatty Change, liver Low Power
Signet ring
cells
12- Fatty Change, liver High Power
Signet ring cells
Normal Cells
15- Chronic Venous Congestion, liver (Diagram)
Degenerated liver cells
Congested Central
vein
Degenerated liver
cells
Portal Tract
15- Chronic Venous Congestion, liver Low Power
15- Chronic Venous Congestion, liver
High Power
Amoebic Liver Abscess 2
1
3
1) Necrotic liver cells 2) Entamoeba histolytica 3) Hepatocytes infiltrated with chronic inflammatory cells
Acute Yellow Atrophy 1
2
3
4
1) Necrotic hepatocytes + interstitial hemorrhage 2) Dilated congested sinusoid 3) Normal-looking bile ductule 4) Chronic inflammatory cells
31- Bilharzial Fibrosis, liver
Portal Cirrhosis 1
2
1) Cirrhotic nodules with absent central veins 2) Bands of vascularized fibrous tissue infiltrated with chronic
inflammatory cells
Portal Cirrhosis
1
2
1) Cirrhotic nodules showing fatty change with absent central veins 2) Bands of vascularized fibrous tissue infiltrated with chronic
inflammatory cells. Blood vessels are dilated
Portal Cirrhosis
Higher power of previous slide
Biliary Cirrhosis
1
2
1) Dilated bile ductules and canaliculi filled with brown bile pigment
2) Cholestasis
Biliary Cirrhosis 1
1) Bands of fibrous tissue surrounding cirrhotic nodule
Hepatocellular Carcinoma
1
1) Cords and clusters of malignant hepatocytes
Proliferative Phase
Glands are regular, round or elongated, Lined by columnar epithelium No secretion
Stroma is dense and cellular
Secretory Phase
Glands are dilated and tortuous Lined with col. Or cuboidal epith. Sub- or supranuclear vacuoles Luminal secretion
Stroma is edematous Cells are plump
Secretory Phase
1
2
Endometrial Hyperplasia
1
2
1) Glands 2) Stroma 3) Hemorrhage
3
Endometrial Hyperplasia
1
2
34- Leiomyoma
Adenocarcinoma, Uterus
1
2
1) Malignant glands 2) Desmoplastic stroma
Adenocarcinoma, Uterus
1
2
1) Malignant glands 2) Desmoplastic stroma 3) Invasion of myometrium
3
Complete Hydatidiform Mole
1
2
1) Chorionic villi 2) Trophoblast
Choriocarcinoma
1
2
1) Cytotrophoblasts (Langhans cells) 2) syncytiotrophoblasts
Fibrocystic changes of Breast 1
2
3
4
5
1) Epitheliosis 2) Cyst 3) Adenosis 4) Fibrosis 5) Apocrine metaplasia
43- Pericanalicular Fibroadenoma
44- Intracanalicular Fibroadenoma
Ductal Carcinoma-in-situ
1
3
2
1) Dilated breast duct filled with malignant cells 2) Central necrosis 3) Stromal fibrosis
54- Infiltrating Duct carcinoma
Rheumatic Myocarditis 1
2
3
1) Myocardium 2) Blood vessels 3) Perivascular Aschoff body
Rheumatic Myocarditis 1
2
1) Fibrinoid degeneration of collagen fibers and interstitial edema 2) Aschoff giant cell
Muscle
Bundles
Fibrous Tissue
Congested
Capillary
Bacterial Endocarditis
1
2
3
1) Ulcerated valve cusp 2) Bacterial colonies 3) Inflammatory cells
Bacterial Endocarditis 1
2
3
1) Sparse inflammatory cells 2) Fibrin 3) Colonies of bacteria
Atheroma
1
2
3
4
5
6
1) Focal calcification 2) Fibrosis 3) Ulcerated
endothelium 4) Foam cells 5) Cholesterol clefts 6) Recanalisation
Colloid Goitre
1
2
1) Acini 2) cyst
1
2
Toxic Goiter
1) Follicle 2) Inflammatory cells
Papillary Carcinoma
1
2
1) Tumor papillae lined by tumor cells 2) Psammoma body
Papillary Carcinoma
1
2
1) Tumor papillae lined by tumor cells 2) Tumor nuclei
18- Infarction, spleen Diagram
Hyperemic Zone
Capsule
Infarct
18- Infarction, spleen Low Power
Infarct
Capsule
Hyperemic Zone
21- T.B. Lymphadenitis Diagram
Langhan’s
Giant Cell
Tubercle
Lymphoid Tissue
21- T.B.Lymphadenitis Low power
Hodgkin’s Lymphoma (Mixed Cellularity Type)
58- Metastatic Carcinoma, Lymph Node
•Soft tissue
25- Rhinoscleroma Diagram
Stratified Squamous
Epithelium Mickulicz cell Lymphocyt
e Russle Body
25- Rhinoscleroma Low Power
26- Actinomycosis Diagram
Chronic inflammatory cells Colony
Multiple abscesses
Fibrous Tissue
Chronic
inflammatory
cells
Fungal Colonies
26- Actinomycosis LOW Power
35- Lipoma
39- Cavernous Lymphangioma
40- Cavernous Hemangioma
bone
37- Chondroma
45- Giant Cell Tumor, Bone
47- Chondrosarcoma
48- Osteosarcoma
Skin
41- Squamous Cell Papilloma
38- Capillary Hemangioma
51- Malignant Melanoma
52- Squamous Cell Carcinoma
53- Basal Cell Carcinoma
Meningioma 1
2
1) Whorls of round, spindle or oval cells 2) Central capillary with hyalinised wall
Meningioma
Multiple psammoma bodies
33- Schwanoma
Astrocytoma
1) Astrocytes with large nuclei and scanty cytoplasm 2) Network of interlacing fibrils
1
2