Post on 31-May-2015
Imaging Department report
February 7th 2012
Reported by Dr. Le Giang
Name: Bui Trang AnhSex: FemaleAge: 22 monthsDept: Outpatient Dept.
Clinical Dx : Abdominal tumor . Dr. Hau (A14)
Clinical Symptoms
Swollen bellyConstipationPainless
US: Large heterogenous mass in the retroperitoneum
CT findings(Pre C+)
Large, heterogenous mass arises from left suprarenal
Volume: 122x120x82 mm.
CT findings(Pre C+)
Extension crossing the midline Irregular lobulated Coarse calcifications. Necrosis areas
CT findings(Pre C+)
Pleural effusion bilateralPleural effusion bilateral Hypodensity areas in liverHypodensity areas in liver
CT findings(Post C+)
Enhances heterogenously . Necrosis areas.. Surrounding and engulfing aorta, celiac artery, superior mesenteric artery.
CT findings(Post C+)
Surrounding and engulfing both renal artery Compressing & displacing IVC and both renal veins to the anterior
CT findings(Post C+)
2 masses are enhanced less than liver parenchyma
CT findings(Post C+)
Some lympho nodes arround the aorta Small amount ascite Bone & Lung metastase: NOT SEEN
Laboratery test: pending…
Diagnosis
Neuroblastoma with liver metastases ( Stage IV)
Neuroblastoma
NB is the most common extracranial solid cancer in childhood & infancy
Malignant tumor of primitive neural crest cells. Most common solid mass in ab of infancy ( 12,3 % of all
perinatal neoplasms) 3rd most common malignance tumor in infancy ( after
leukemia and cns tumor), 2nd most common in childhood ( wilm tumor more common in older children)
It is a Neuroendocrine tumor. Most commonly arises from adrenal gland but can arise anywhere along sympathetic chain from Neck to Pelvis
Age: neonatal 8y. Peak : 22months .Younger age with better prognosis.
M:F = 1:1
Neuroblastoma
CT finding:Mass often heterogeneous from necrosis,
hemorrhageCalcification seen on CT in up to 85% Invasive pattern of growth with engulfing
rather than displacing vessels
Neuroblastoma
Staging:
Anatomic staging (prognosis - % survival) 1: Confined to organ of interest (90%) 2: Extension beyond organ but not crossing
midline (75%) 3: Extension crossing midline (30%) 4: Distal metastasis (10%) 4S: Age < 1 year, metastatic disease confined to
skin, liver, and bone marrow (near 100%)
Thank youThank you