Oncology at Saint-Joseph Hospital

Prof. Eric Raymond, MD, PhD

eraymond@hpsj.fr

Cancer complexity from genetic to clinical levels

Basic issues in medical oncology

• Comprehensive evaluation at diagnostic and recurrences (chronic disease)

• Multidisciplinary care

• Patient pre-habilitation and re-habilitation prior to cancer therapy

• The constant progresses, the complexity of multidisciplinary medical care and long term follow up required for each cancer patient require continuous training for medical and paramedical professional

Saint-Joseph oncology background

• Organize quick and comprehensive workup to speed up patient care

• Take any decision for individual in a multidisciplinary manner, based on documented medical evidences

• Understand patient needs (nutrition, physical activities, psychological issues) to prepare for anticancer treatment appropriately

• Ensure continuous medical and paramedical trainings

Medical expertise: Type of tumors

• Thoracic oncology

• Breast cancer

• Gynecological cancer (GYN)• Uterine (cervix and corpus) • Ovarian carcinoma

• GI tumor (GI)• Colorectal cancer• Esophageal cancer• Gastric cancer• Anal margin• Pancreatic cancer• Primary liver tumors

• Hepatocellular carcinoma• Cholangiocarcinoma

• Urinary track cancers (GU)• Prostate adenocarcinoma• Bladder cancer• Kidney cancer• Testicular cancer

• Head and neck tumors• Squamous cell• Adenocarcinoma

• Rare tumor types• Neuroendocrine tumors• Sarcomas• Skin cancer (Melanoma and squamous)• Brain tumors• Carcinoma of unknown primary

• Lymphomas

Multidisciplinary evaluations and decisions

Imaging diagnostic

PathologyInterventional

radiology

Multidisciplinary decisions for therapySurgery

Radiotherapy

Interventional radiology

Chemotherapy

Targeted therapy

Immunotherapy

Radionuclide therapies

Clinical and translational cancer options

Rehabilitation and pre-habilitation therapy

Palliative care and pain therapy

Imaging (CT, MRI, PET)

Pathology

Molecular biology

Genetic counseling

Individualizedtreatment decision

& strategy

Surgery

• Pre-habilitation to optimize patient recovery and outcome

• Outpatient surgery

• Robotic surgery

• PIPAC : Pressurized Intraperitoneal Aerosol Chemotherapy

Interventional radiology

• Transcutaneous radiofrequency

• Chemoembolization

• Intra-arterial chemotherapy

• Per-operative radiofrequency and cryotherapy ablation

Medical oncology

• Chemotherapy

• Targeted therapy• Anti-oncogenic agents

• Antiangiogenic agents

• Immunotherapy• Checkpoint inhibitors

• Vaccination

Combined strategies

Combine multiple approaches to optimize the overall survival benefit and quality of life of patients

Clinical & Translational Cancer Research

• National and international networking for cancer research• France (INCa, FFCD, GERCOR, GETUG)

• European• EORTC (www.eortc.org)

• OncDistinct

• PAMM

• ENETS

• International• WIN (ASCO)

• AACR (ENA)

International patients

• Quick evaluation of treatment options (<3 days)

• Medical advise or proposal for care in Saint-Joseph

• Fair quotations of patient care

Medical and paramedical training

• Physicians in medical and scientific training (theoretical adn at patient bedside)

• MD and PhD formation

• Medical oncology specialization

• Paramedical formation

Areas of potential collaborations

• Medical and paramedical training

• Medical expertise

• Data mining

• Translational and Clinical Research

• Hospitality for selected cases requiring care in France

Conclusion

• Comprehensive multidisciplinary cancer care at Saint-Joseph Hospital to match medical needs

• Potential for collaborations in welcoming physicians in training for doctoral and post-doctoral positions (MD, PhD) for medicine and/or research

• Potential for collaboration for paramedical formation

• Interest for networking in clinical and translationalresearch

Thanks for your attention