Post on 08-Jun-2020
Modeling III Linear Stability Analysis
Nondimensional Equa9ons From previous lecture, we have a system of nondimensional PDEs:
(22.1)
(22.2)
(22.3)
where here the “*” sign has been dropped for convenience.
Parameters The parameter values:
Initial conditions:
Boundary conditions: zero-flux on all boundaries.
Homogeneous Steady States
leaving
A homogeneous steady state of a PDE model is a solution that is constant in space in time. For equations (22.1), (22.2), and (22.3) we take
(22.4)
(22.5)
(22.6)
Homogeneous Steady States
Hence, there are four possible steady state points:
Possibilities of steady state points:
(22.7)
Inhomogeneous Perturba9ons
• It is of interest to determine whether or not the steady states are stable.
• We analyze stability properties by considering the effect of small perturbations.
• To do this, we must look at spatially non-uniform (also called inhomogeneous) perturbations and explore whether they are amplified or attenuated.
• If an amplification occurs, then a situation close to the spatially uniform steady state will destabilize, leading to some new state in which spatial variations predominate.
Inhomogeneous Perturba9ons We take the distributions of the variables
where are small.
Using the facts that are constants and uniform, the temporal and spatial derivatives give
Inhomogeneous Perturba9ons The second-order spatial derivatives give:
For taxis terms: (22.8)
Inhomogeneous Perturba9ons The terms
are quadratic in the perturbations or their derivatives and consequently are of smaller magnitude than other terms, thus they can be omitted, leaving
and, similarly
(22.9)
(22.10)
Inhomogeneous Perturba9ons And for the reaction terms:
Inhomogeneous Perturba9ons Combining all together we rewrite the approximate linearized equations of (22.1) – (22.3) as
which are linear in the quantities
(22.11)
(22.12)
(22.13)
Finding Eigenvalues We find eigenvalues by setting the equations (22.11), (22.12), and (22.13) to have no spatial variations, or
Then let
(22.14)
(22.15)
(22.16)
Finding Eigenvalues Differentiating with respect to gives us a Jacobian matrix of the reaction terms:
Eigenvalues are obtained by taking (22.17)
(22.18)
Stability of the Steady States Steady states in (22.7) are linearly stable if Re λ < 0 since in this case the perturbations go to zero as time goes to infinity.
Using the parameter values given and substituting into (22.18), we obtain the stability of the steady state:
gives 2 λ > 0 and 1 λ < 0 : unstable
gives 1 λ > 0 and 2 λ < 0 : unstable
gives 3 λ < 0 : stable
gives 1 λ > 0 and 2 λ < 0 : unstable
Dispersion Rela9on Now we consider the full equations (22.11) – (22.13) and differentiate with respect to the second-order spatial derivatives
to get the transport Jacobian
(22.19)
Dispersion Rela9on The linearized system of equations (22.11) – (22.13) can now be represented in a compact form
to be solved in a domain with zero-flux boundary conditions
where
(22.20)
(22.21)
Dispersion Rela9on To solve the system of equations in (22.20) subject to the boundary conditions, we first define W(r) to be the time-independent solution of the spatial eigenvalue problem, defined by
where k is the eigenvalue. For example, if the domain is 1D, say , then
where n is an integer. This satisfies zero-flux boundary conditions at x = 0 and x = L.
(22.22)
Dispersion Rela9on The eigenvalue in this case is
So
We shall refer to k in this context as the wavenumber.
is a measure of the wavelike pattern: the eigenvalue k is called the wavenumber and 1/k is proportional to the wavelength ω:
Dispersion Rela9on With finite domains there is a discrete set of possible wavenumbers since n is an integer.
We now look for solutions of (22.20) in the form
Substituting (22.23) into (22.20) with (22.21) and canceling we get, for each k,
(22.23)
Dispersion Rela9on We require nontrivial solutions for Wk so the now the λ are determined by the roots of
Evaluating the determinant with JT and JR we get the eigenvalues λ(k) as functions of the wavenumber k.
(22.24)
Dispersion Rela9on Dispersion relation from steady state (0,0,0)
• Max real part (blue line) of eigenvalues is 0.25
• It means that the perturbation grows with time.
• Imaginary part (red line) is zero.
• With the max real part, there are a range of k where the eigenvalues are positive.
k
λ(k)
Dispersion Rela9on Dispersion relation from steady state (0,1,0)
• Max real part (blue line) of eigenvalues is 0.25.
• The perturbation grows with time.
• Imaginary part (red line) is zero.
• There are a range of k (between k=0 and k⋍30) where the eigenvalues are positive.
k
λ(k)
Dispersion Rela9on Dispersion relation from steady state
• Max real part (blue line) of eigenvalues is -0.0477.
• The perturbation is damped away.
• Imaginary part (red line) is zero.
k
λ(k)
Dispersion Rela9on Dispersion relation from steady state
• Max real part (blue line) of eigenvalues is 3.725.
• Max imaginary part (red line) is 2.1374.
• The perturbations grows with time.
• Imaginary part creates oscillating solutions.
k
λ(k)
Simula9on Results
References (1) Mathematical Biology II: Spatial Models and Biomedical
Applications, J.D. Murray, Springer, Third Edition.